List of works by Alpha Yap

A Mechanosensitive RhoA Pathway that Protects Epithelia against Acute Tensile Stress

scientific article published on 11 October 2018

A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens.

scientific article

A bigger picture: classical cadherins and the dynamic actin cytoskeleton.

scientific article published on 30 August 2012

A dileucine motif targets E-cadherin to the basolateral cell surface in Madin-Darby canine kidney and LLC-PK1 epithelial cells.

scientific article published on 18 April 2001

A mechanobiological perspective on cadherins and the actin-myosin cytoskeleton

scientific article published on 02 September 2013

Acromegaly first diagnosed in pregnancy: the role of bromocriptine therapy.

scientific article published in August 1990

Active contractility at E-cadherin junctions and its implications for cell extrusion in cancer

scientific article

Active tension: the role of cadherin adhesion and signaling in generating junctional contractility

scientific article

Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking

scientific article published on 24 February 2015

Adherens Junctions Revisualized: Organizing Cadherins as Nanoassemblies

scientific article published on October 2015

An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions

scientific article published on 28 January 2015

An α-catenin déjà vu.

scientific article published in March 2013

Anillin: The First Proofreading-like Scaffold?

scientific article published on 31 July 2020

Another Job for the Talented p120-Catenin

scientific article published on 01 December 2006

Arp2/3 activity is necessary for efficient formation of E-cadherin adhesive contacts

scientific article

Autosomal dominant primary hyperparathyroidism and jaw tumor syndrome associated with renal hamartomas and cystic kidney disease: linkage to 1q21-q32 and loss of the wild type allele in renal hamartomas

scientific article published in December 1996

Biomechanical guidance helps elongate a lumen.

scientific article published in February 2016

Bistable front dynamics in a contractile medium: Travelling wave fronts and cortical advection define stable zones of RhoA signaling at epithelial adherens junctions

scientific article

Blunted Parathyroid Response to Correction of Hypercalcemia in Subjects with Squamous Cell Carcinoma

article

Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epithelia

scientific article

Cadherin junctions and their cytoskeleton(s).

scientific article

Cadherin-directed actin assembly: E-cadherin physically associates with the Arp2/3 complex to direct actin assembly in nascent adhesive contacts

scientific article

Cadherin-mediated adhesion and apical membrane assembly define distinct steps during thyroid epithelial polarization and lumen formation

scientific article published on October 1995

Cadherins and cancer: how does cadherin dysfunction promote tumor progression?

scientific article

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.

scientific article published on 6 February 2018

Caveolae Protect Notochord Cells against Catastrophic Mechanical Failure during Development.

scientific article published on 14 June 2017

Cell-cell contact: cooperating clusters of actin and cadherin.

scientific article published in August 2008

Cell-to-cell contact and extracellular matrix

Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens

scientific article published on July 2012

Characterization of E-cadherin endocytosis in isolated MCF-7 and chinese hamster ovary cells: the initial fate of unbound E-cadherin.

scientific article published on 25 March 2003

Characterization of cell polarity and epithelial junctions in the choriocarcinoma cell line, JAR.

scientific article published on January 1995

Cinderella no longer: alpha-catenin steps out of cadherin's shadow

scientific article published on November 2006

Classical cadherin adhesion molecules: coordinating cell adhesion, signaling and the cytoskeleton

scientific article

Contact inhibition (of proliferation) redux

scientific article

Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates

scientific article

Contextual binding of p120ctn to E-cadherin at the basolateral plasma membrane in polarized epithelia

scientific article published on 14 August 2003

Coordinating Rho and Rac: the regulation of Rho GTPase signaling and cadherin junctions

scientific article published on January 2013

Coronin 1B Reorganizes the Architecture of F-Actin Networks for Contractility at Steady-State and Apoptotic Adherens Junctions

scientific article published on April 2016

Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II

scientific article published on 20 September 2016

Cortactin is a functional target of E-cadherin-activated Src family kinases in MCF7 epithelial monolayers

scientific article published on 19 May 2009

Cortactin is necessary for E-cadherin-mediated contact formation and actin reorganization

scientific article

Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens

scientific article published on 27 January 2014

Cortactin: Coordinating adhesion and the actin cytoskeleton at cellular protrusions

scientific article published on October 2009

Cortical F-actin stabilization generates apical-lateral patterns of junctional contractility that integrate cells into epithelia.

scientific article published on 12 January 2014

Coupling adhesion to actin bundles in the inner ear. Novel functions for novel cadherins

scientific article

Current perspectives on cadherin-cytoskeleton interactions and dynamics

Differential regulation of thyroid cell-cell and cell-substrate adhesion by thyrotropin

scientific article published on October 1992

Direct cadherin-activated cell signaling: a view from the plasma membrane

scientific article (publication date: 6 January 2003)

Doing cell biology in embryos: regulated membrane traffic and its implications for cadherin biology

scientific article

Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries

scientific article

Dynamic microtubules regulate the local concentration of E-cadherin at cell-cell contacts

scientific article published on 11 April 2006

E-cadherin adhesion activates c-Src signaling at cell-cell contacts

scientific article

E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts

scientific article published on 13 December 2001

E-cadherin junctions as active mechanical integrators in tissue dynamics

scientific article published on May 2015

E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transition

scientific article

E-cadherin supports steady-state Rho signaling at the epithelial zonula adherens

scientific article published on 2 May 2013

Ena/VASP proteins can regulate distinct modes of actin organization at cadherin-adhesive contacts

scientific article

Endocytic crosstalk: cavins, caveolins, and caveolae regulate clathrin-independent endocytosis

scientific article

Endocytosis, cadherins and tissue dynamics

scientific article published on 07 January 2020

Endothelial cell-cell adhesion during zebrafish vascular development

scientific article

Epstein-Barr virus associated modulation of Wnt pathway is not dependent on latent membrane protein-1.

scientific article

Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions.

scientific article

Gab2 and Src co-operate in human mammary epithelial cells to promote growth factor independence and disruption of acinar morphogenesis.

scientific article published on 12 November 2007

Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion

scientific article

HOXA1 is required for E-cadherin-dependent anchorage-independent survival of human mammary carcinoma cells

scientific article published on 22 December 2005

Hepatocyte Growth Factor Acutely Perturbs Actin Filament Anchorage at the Epithelial Zonula Adherens

scientific article published on 01 March 2011

Initiation of cell locomotility is a morphogenetic checkpoint in thyroid epithelial cells regulated by ERK and PI3-kinase signals

scientific article published in June 2001

Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers

scientific article published on 18 February 2021

Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis

scientific article

Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish

scientific article published on 10 November 2017

Making a Choice: How Cadherin Switching Controls Cell Migration

scientific article published in August 2015

Making and breaking contacts: the cellular biology of cadherin regulation

scientific article published on October 2007

Mammalian Diaphanous 1 Mediates a Pathway for E-cadherin to Stabilize Epithelial Barriers through Junctional Contractility.

scientific article published in March 2017

Mammalian farnesyltransferase α subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A)--dependent intracellular trafficking through recycling endosomes.

scientific article

Mechanosensing and Mechanotransduction at Cell-Cell Junctions.

scientific article published on 4 August 2017

Minimal mutation of the cytoplasmic tail inhibits the ability of E-cadherin to activate Rac but not phosphatidylinositol 3-kinase: direct evidence of a role for cadherin-activated Rac signaling in adhesion and contact formation

scientific article published on 2 April 2003

Modelling wound closure in an epithelial cell sheet using the cellular Potts model

scientific article published on 29 June 2015

Molecular analyses of tight junction physiology: insights and paradoxes

scientific article published in June 1998

Molecular and functional analysis of cadherin-based adherens junctions

scientific article published on January 1997

Morphogenesis in Kyoto: a confluence of cell and developmental biology

scientific article published on 20 January 2010

Multicomponent analysis of junctional movements regulated by myosin II isoforms at the epithelial zonula adherens

scientific article

Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization

scientific journal article

Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contacts

scientific article

Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens

scientific article

Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cells

scientific article

N-WASP regulates the epithelial junctional actin cytoskeleton through a non-canonical post-nucleation pathway.

scientific article published on 24 July 2011

Neighborly relations: cadherins and mechanotransduction.

scientific article published on June 2010

Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension.

scientific article

Not so simple: the complexity of phosphotyrosine signaling at cadherin adhesive contacts

scientific article published on 11 April 2007

Notching a New Pathway in Vascular Flow Sensing

scientific article published on 2 January 2018

On giant's shoulders: an interview with Masatoshi Takeichi (RIKEN Center for Developmental Biology, Kobe).

scientific article published on 29 October 2013

Organizing Junctions at the Cell-Cell Interface

scientific article published on 01 November 2008

Patterns in space: coordinating adhesion and actomyosin contractility at E-cadherin junctions.

scientific article

Phosphatidylinositol 3'-kinase signalling supports cell height in established epithelial monolayers.

scientific article published in October 2009

Pli Selon Pli: Mechanochemical Feedback and the Morphogenetic Role of Contractility at Cadherin Cell-Cell Junctions

scientific article published on 7 January 2016

Preface. Cellular adhesion in development and disease

scientific article

Productive tension: force-sensing and homeostasis of cell-cell junctions

scientific article published on 15 July 2011

Protein tyrosine phosphatase activity is necessary for E-cadherin-activated Src signaling

scientific article published on 29 November 2010

Protein tyrosine phosphorylation influences adhesive junction assembly and follicular organization of cultured thyroid epithelial cells

scientific article published on 01 June 1997

Pulsatile contractility of actomyosin networks organizes the cellular cortex at lateral cadherin junctions

scientific article published on 16 September 2014

ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens

scientific article

RPTPα controls epithelial adherens junctions, linking E-cadherin engagement to c-Src-mediated phosphorylation of cortactin.

scientific article published on 20 March 2014

Rac is a dominant regulator of cadherin-directed actin assembly that is activated by adhesive ligation independently of Tiam1.

scientific article published on 4 October 2006

Recruitment of phosphoinositide 3-kinase defines a positive contribution of tyrosine kinase signaling to E-cadherin function

scientific article published on 19 November 2004

Regulated recruitment of SRGAP1 modulates RhoA signaling for contractility during epithelial junction maturation.

scientific article published on 21 November 2017

Regulation of thyroid follicular volume by bidirectional transepithelial ion transport

scientific article

Remodeling the zonula adherens in response to tension and the role of afadin in this response

scientific article

Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling

scientific article published on 3 June 2016

Role of contact inhibition of locomotion and junctional mechanics in epithelial collective responses to injury.

scientific article

Seeing and believing: recent advances in imaging cell-cell interactions

scientific article

Selective liquid chromatographic assay for propylthiouracil in plasma ⬇️

scientific article published on 01 March 1991

Self-organizing actomyosin patterns on the cell cortex at epithelial cell-cell junctions

scientific article

Single-dose intravenous pamidronate is effective alternative therapy for Paget's disease refractory to calcitonin.

scientific article

Targeted Genome Editing via CRISPR in the Pathogen Cryptococcus neoformans.

scientific article

Tensile Forces and Mechanotransduction at Cell-Cell Junctions.

scientific article published in April 2018

Tension-sensitive actin assembly supports contractility at the epithelial zonula adherens

scientific article published on 24 July 2014

The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling

scientific article published on 26 May 2016

The Nuclear Receptor, RORγ, Regulates Pathways Necessary for Breast Cancer Metastasis

scientific article published on 18 February 2016

The SNX-PX-BAR family in macropinocytosis: the regulation of macropinosome formation by SNX-PX-BAR proteins

scientific article published in 2010

The challenges of abundance: epithelial junctions and small GTPase signalling.

scientific article

The cytoskeleton and classical cadherin adhesions

scientific article published on January 2012

The effect of time-dependent deformation of viscoelastic hydrogels on myogenic induction and Rac1 activity in mesenchymal stem cells

scientific article published on 9 December 2013

The membrane environment of cadherin adhesion receptors: a working hypothesis

scientific article published on 05 July 2019

The regulation and functional impact of actin assembly at cadherin cell-cell adhesions.

scientific article published on 16 January 2013

The web and the rock: cell adhesion and the ARP2/3 complex

scientific article

Thyroid Cell Spreading and Focal Adhesion Formation Depend upon Protein Tyrosine Phosphorylation and Actin Microfilaments

scientific article published on 01 February 1994

Thyrotropin inhibits the intrinsic locomotility of thyroid cells organized as follicles in primary culture.

scientific article

Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation

scientific article published on April 2011

Tmem2 Regulates Embryonic Vegf Signaling by Controlling Hyaluronic Acid Turnover

scientific article published on 01 February 2017

Touch, grasp, deliver and control: functional cross-talk between microtubules and cell adhesions

scientific article published on 17 January 2009

Towards a Dynamic Understanding of Cadherin-Based Mechanobiology

scientific article

Traffic control: p120-catenin acts as a gatekeeper to control the fate of classical cadherins in mammalian cells

scientific article published on November 2003

Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherens

scientific article published on 01 December 2014

Tuba and N-WASP function cooperatively to position the central lumen during epithelial cyst morphogenesis

scientific article published on July 2011

Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1.

scientific article published on 5 October 2017

Vegfc Regulates Bipotential Precursor Division and Prox1 Expression to Promote Lymphatic Identity in Zebrafish.

scientific article

Versatile Scaffold: Extrajunctional Roles for α-Catenin.

scientific article published in November 2017

Vinculin localization and actin stress fibers differ in thyroid cells organized as monolayers or follicles

scientific article

Vinculin, cadherin mechanotransduction and homeostasis of cell-cell junctions

scientific article published on 29 December 2012

When domestiques rebel: kinesins, cadherins and neuronal proliferation

scientific article published in May 2005

α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction

scientific article published on 12 February 2014

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