List of works - Cristina Muñoz-Pinedo

"(Not) all (dead) things share the same breath": identification of cell death mechanisms in anticancer therapy

scientific article

2-deoxyglucose induces Noxa-dependent apoptosis in alveolar rhabdomyosarcoma

scientific article published on 12 September 2011

A role for caspase-8 and TRAIL-R2/DR5 in ER-stress-induced apoptosis

scientific article published on 6 October 2017

ATF4 mediates necrosis induced by glucose deprivation and apoptosis induced by 2-deoxyglucose in the same cells

scientific article published on 14 July 2015

Analysis of BH3-only proteins upregulated in response to oxygen/glucose deprivation in cortical neurons identifies Bmf but not Noxa as potential mediator of neuronal injury

scientific article

Apolipoprotein L2 contains a BH3-like domain but it does not behave as a BH3-only protein

scientific article published on 5 June 2014

Autosis: a new addition to the cell death Tower of Babel

scientific article published on 10 July 2014

Cancer metabolism: current perspectives and future directions

scientific article published on 12 January 2012

Cell death induced by endoplasmic reticulum stress.

scientific article

Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress

scientific article (publication date: 13 June 2016)

Confocal restricted-height imaging of suspension cells (CRISC) in a PDMS microdevice during apoptosis

scientific article published on 9 May 2005

Correlated three-dimensional light and electron microscopy reveals transformation of mitochondria during apoptosis

scientific article

Cytochrome c is released in a single step during apoptosis

scientific article published in May 2005

Death on the beach: a rosy forecast for the 21st century

scientific article published on 01 September 2002

DeathBase: a database on structure, evolution and function of proteins involved in apoptosis and other forms of cell death

scholarly article by J Díez et al published 12 April 2010 in Cell Death & Differentiation

Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration

scientific article

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

scientific article

Disruption of the M80-Fe ligation stimulates the translocation of cytochrome c to the cytoplasm and nucleus in nonapoptotic cells

scientific article

Emerging concepts: linking hypoxic signaling and cancer metabolism.

scientific article published on 3 May 2012

Emerging concepts: linking hypoxic signaling and cancer metabolism.

scientific article published on 21 June 2012

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications

scientific article published on 04 August 2018

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

scientific article

Exploiting tumor vulnerabilities: epigenetics, cancer metabolism and the mTOR pathway in the era of personalized medicine

scientific article published on 17 May 2013

Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors

scientific article

Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells.

scientific article

Glucose-starved cells do not engage in prosurvival autophagy

scientific article published on 6 September 2013

Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.

scientific article published on 7 December 2009

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

In the Hunger Games, the Winner Takes Everything

scientific article published on 28 August 2017

Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing

scientific article published on 29 January 2003

Interferon-γ Sensitizes Human Myeloid Leukemia Cells to Death Receptor-mediated Apoptosis by a Pleiotropic Mechanism

scientific article published on 14 February 2001

Measuring apoptosis at the single cell level

scientific article published on March 2008

Measuring the Activation of Cell Death Pathways upon Inhibition of Metabolism

scientific article published on 01 January 2019

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy

scientific article

Regulation of cancer metabolism by oncogenes and tumor suppressors

scientific article published on January 2014

Resistance to caspase-independent cell death requires persistence of intact mitochondria

scientific article published on May 2010

Signaling pathways that regulate life and cell death: evolution of apoptosis in the context of self-defense

scientific article published on January 2012

Stalling the engine of resistance: targeting cancer metabolism to overcome therapeutic resistance

scientific article published on 22 April 2013

Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells

scientific article published on 20 April 2020

Sugar-free approaches to cancer cell killing

scientific article published on 25 October 2010

The differential sensitivity of Bc1-2-overexpressing human breast tumor cells to TRAIL or doxorubicin-induced apoptosis is dependent on Bc1-2 protein levels.

scientific article

The importance of being dead: cell death mechanisms assessment in anti-sarcoma therapy.

scientific article published on 07 April 2015

Thymidylate synthase inhibition triggers glucose-dependent apoptosis in p53-negative leukemic cells

scientific article published on July 2004

Transmissible cytotoxicity of multiple myeloma cells by cord blood-derived NK cells is mediated by vesicle trafficking

scientific article

List of works by Cristina Muñoz-Pinedo

"(Not) all (dead) things share the same breath": identification of cell death mechanisms in anticancer therapy

2-deoxyglucose induces Noxa-dependent apoptosis in alveolar rhabdomyosarcoma

A role for caspase-8 and TRAIL-R2/DR5 in ER-stress-induced apoptosis

ATF4 mediates necrosis induced by glucose deprivation and apoptosis induced by 2-deoxyglucose in the same cells

Analysis of BH3-only proteins upregulated in response to oxygen/glucose deprivation in cortical neurons identifies Bmf but not Noxa as potential mediator of neuronal injury

Apolipoprotein L2 contains a BH3-like domain but it does not behave as a BH3-only protein

Autosis: a new addition to the cell death Tower of Babel

Cancer metabolism: current perspectives and future directions

Cell death induced by endoplasmic reticulum stress.

Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress

Confocal restricted-height imaging of suspension cells (CRISC) in a PDMS microdevice during apoptosis

Correlated three-dimensional light and electron microscopy reveals transformation of mitochondria during apoptosis

Cytochrome c is released in a single step during apoptosis

Death on the beach: a rosy forecast for the 21st century

DeathBase: a database on structure, evolution and function of proteins involved in apoptosis and other forms of cell death

Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

Disruption of the M80-Fe ligation stimulates the translocation of cytochrome c to the cytoplasm and nucleus in nonapoptotic cells

Emerging concepts: linking hypoxic signaling and cancer metabolism.

Emerging concepts: linking hypoxic signaling and cancer metabolism.

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

Exploiting tumor vulnerabilities: epigenetics, cancer metabolism and the mTOR pathway in the era of personalized medicine

Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors

Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells.

Glucose-starved cells do not engage in prosurvival autophagy

Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

In the Hunger Games, the Winner Takes Everything

Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing

Interferon-γ Sensitizes Human Myeloid Leukemia Cells to Death Receptor-mediated Apoptosis by a Pleiotropic Mechanism

Measuring apoptosis at the single cell level

Measuring the Activation of Cell Death Pathways upon Inhibition of Metabolism

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy

Regulation of cancer metabolism by oncogenes and tumor suppressors

Resistance to caspase-independent cell death requires persistence of intact mitochondria

Signaling pathways that regulate life and cell death: evolution of apoptosis in the context of self-defense

Stalling the engine of resistance: targeting cancer metabolism to overcome therapeutic resistance

Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells

Sugar-free approaches to cancer cell killing

The differential sensitivity of Bc1-2-overexpressing human breast tumor cells to TRAIL or doxorubicin-induced apoptosis is dependent on Bc1-2 protein levels.

The importance of being dead: cell death mechanisms assessment in anti-sarcoma therapy.

Thymidylate synthase inhibition triggers glucose-dependent apoptosis in p53-negative leukemic cells

Transmissible cytotoxicity of multiple myeloma cells by cord blood-derived NK cells is mediated by vesicle trafficking