List of works - Zhihong Guo

A Thiamine-Dependent Enzyme Utilizes an Active Tetrahedral Intermediate in Vitamin K Biosynthesis

scientific article

A chemical approach to generate molecular diversity based on the scaffold of cyclic decapeptide antibiotic tyrocidine A

scientific article

A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition.

scientific article published on 12 May 2016

B-cell responses in patients who have recovered from severe acute respiratory syndrome target a dominant site in the S2 domain of the surface spike glycoprotein

scientific article

Biomimetic Synthesis of Gramicidin S and Analogues by Enzymatic Cyclization of Linear Precursors on Solid Support ⬇️

scientific article published on May 15, 2003

Cascade biocatalysis by multienzyme-nanoparticle assemblies

scientific article published on 16 July 2014

Catalytic mechanism of SHCHC synthase in the menaquinone biosynthesis of Escherichia coli: identification and mutational analysis of the active site residues.

scientific article

Chip-based CE coupled to a quadrupole TOF mass spectrometer for the analysis of a glycopeptide

scientific article

Combination of beta-elimination and liquid chromatography/quadrupole time-of-flight mass spectrometry for the determination of O-glycosylation sites

scientific article published on 27 November 2008

Conjugation of latent membrane protein (LMP)-2 epitope to gold nanoparticles as highly immunogenic multiple antigenic peptides for induction of Epstein-Barr virus-specific cytotoxic T-lymphocyte responses in vitro

scientific article published in January 2009

Crystal structure of the thioesterification conformation of Bacillus subtilis o-succinylbenzoyl-CoA synthetase reveals a distinct substrate-binding mode.

scientific article published on 30 May 2017

Crystal structures of E. coli native MenH and two active site mutants

scientific article published in 2013

Determination of the stereochemistry of 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate, a key intermediate in menaquinone biosynthesis.

scientific article

Discovery of pentacyclic triterpenoids as potential entry inhibitors of influenza viruses

scientific article

Dissociation of antibacterial and hemolytic activities of an amphipathic peptide antibiotic.

scientific article

Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles

scientific article

Effects of macromolecular crowding on the intrinsic catalytic efficiency and structure of enterobactin-specific isochorismate synthase.

scientific article published in January 2007

Identification and characterization of a methionine γ-lyase in the calicheamicin biosynthetic cluster of Micromonospora echinospora

scientific article

Identification of a hotdog fold thioesterase involved in the biosynthesis of menaquinone in Escherichia coli

scientific article

Identification of an amphipathic peptide sensor of the Bacillus subtilis fluid membrane microdomains

scientific article published on 20 August 2019

Induction of cytotoxic T cell response against HCA661 positive cancer cells through activation with novel HLA-A *0201 restricted epitopes

scientific article

Insights into the Branched-Chain Formation of Mycarose: Methylation Catalyzed by an (S)-Adenosylmethionine-Dependent Methyltransferase

scientific article published on 01 February 2001

Insights into the Branched-Chain Formation of Mycarose: Methylation Catalyzed by an (S)-Adenosylmethionine-Dependent Methyltransferase We are grateful to Dr. Eugene Seno and the Lilly Research Laboratories for their generous gift of the plasmid pHJL

scientific article published in February 2001

Ligand-dependent active-site closure revealed in the crystal structure of Mycobacterium tuberculosis MenB complexed with product analogues

scientific article

Menaquinone biosynthesis in Escherichia coli: identification of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a novel intermediate and re-evaluation of MenD activity

scientific article

Molecular Basis of the General Base Catalysis of an / -Hydrolase Catalytic Triad

scientific article

Nitrilotriacetic acid-modified magnetic nanoparticles as a general agent to bind histidine-tagged proteins

scientific article published in March 2004

Phenylacetyl pepstatin inhibitors of aspartyl proteases from Streptomyces varsoviensis

Single-Turnover Kinetics Reveal a Distinct Mode of Thiamine Diphosphate-Dependent Catalysis in Vitamin K Biosynthesis

scientific article published on 19 June 2018

Solid-phase total synthesis and antimicrobial activities of loloatins A-D

scientific article published on 01 December 2007

Stabilization of the Second Oxyanion Intermediate by 1,4-Dihydroxy-2-naphthoyl-Coenzyme A Synthase of the Menaquinone Pathway: Spectroscopic Evidence of the Involvement of a Conserved Aspartic Acid ⬇️

scientific article published on June 8, 2011

Structural Basis for the ATP-dependent Configuration of Adenylation Active Site in Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase

scientific article published on 14 August 2015

Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis

scientific article

Structural basis of the induced-fit mechanism of 1,4-dihydroxy-2-naphthoyl coenzyme A synthase from the crotonase fold superfamily

scientific article

Substrate Recognition and Catalytic Mechanism of the Phosphate Acyltransferase PlsX from Bacillus subtilis

scientific article published on 16 March 2020

Substrate spectrum of tyrocidine thioesterase probed with randomized peptide N-acetylcysteamine thioesters.

scientific article

Synthesis of gramicidin S and its analogues via an on-resin macrolactamization assisted by a predisposed conformation of the linear precursors.

scientific article published in April 2004

Synthesis of tyrocidine A and its analogues by spontaneous cyclization in aqueous solution

scientific article published on 01 August 2002

T-Cell Epitopes in Severe Acute Respiratory Syndrome (SARS) Coronavirus Spike Protein Elicit a Specific T-Cell Immune Response in Patients Who Recover from SARS.

scientific article published in July 2004

T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus spike protein elicit a specific T-cell immune response in patients who recover from SARS.

scientific article

The biosynthesis of GDP-L-colitose: C-3 deoxygenation is catalyzed by a unique coenzyme B6-dependent enzyme

scientific article published on May 2003

Two active site arginines are critical determinants of substrate binding and catalysis in MenD, a thiamine-dependent enzyme in menaquinone biosynthesis

scientific article published on 30 November 2018

Using β-Lactamase to Trigger Supramolecular Hydrogelation

scientific article published on 01 January 2007

List of works by Zhihong Guo

A Thiamine-Dependent Enzyme Utilizes an Active Tetrahedral Intermediate in Vitamin K Biosynthesis

A chemical approach to generate molecular diversity based on the scaffold of cyclic decapeptide antibiotic tyrocidine A

A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition.

B-cell responses in patients who have recovered from severe acute respiratory syndrome target a dominant site in the S2 domain of the surface spike glycoprotein

Biomimetic Synthesis of Gramicidin S and Analogues by Enzymatic Cyclization of Linear Precursors on Solid Support ⬇️

Cascade biocatalysis by multienzyme-nanoparticle assemblies

Catalytic mechanism of SHCHC synthase in the menaquinone biosynthesis of Escherichia coli: identification and mutational analysis of the active site residues.

Chip-based CE coupled to a quadrupole TOF mass spectrometer for the analysis of a glycopeptide

Combination of beta-elimination and liquid chromatography/quadrupole time-of-flight mass spectrometry for the determination of O-glycosylation sites

Conjugation of latent membrane protein (LMP)-2 epitope to gold nanoparticles as highly immunogenic multiple antigenic peptides for induction of Epstein-Barr virus-specific cytotoxic T-lymphocyte responses in vitro

Crystal structure of the thioesterification conformation of Bacillus subtilis o-succinylbenzoyl-CoA synthetase reveals a distinct substrate-binding mode.

Crystal structures of E. coli native MenH and two active site mutants

Determination of the stereochemistry of 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate, a key intermediate in menaquinone biosynthesis.

Discovery of pentacyclic triterpenoids as potential entry inhibitors of influenza viruses

Dissociation of antibacterial and hemolytic activities of an amphipathic peptide antibiotic.

Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles

Effects of macromolecular crowding on the intrinsic catalytic efficiency and structure of enterobactin-specific isochorismate synthase.

Identification and characterization of a methionine γ-lyase in the calicheamicin biosynthetic cluster of Micromonospora echinospora

Identification of a hotdog fold thioesterase involved in the biosynthesis of menaquinone in Escherichia coli

Identification of an amphipathic peptide sensor of the Bacillus subtilis fluid membrane microdomains

Induction of cytotoxic T cell response against HCA661 positive cancer cells through activation with novel HLA-A *0201 restricted epitopes

Insights into the Branched-Chain Formation of Mycarose: Methylation Catalyzed by an (S)-Adenosylmethionine-Dependent Methyltransferase

Insights into the Branched-Chain Formation of Mycarose: Methylation Catalyzed by an (S)-Adenosylmethionine-Dependent Methyltransferase We are grateful to Dr. Eugene Seno and the Lilly Research Laboratories for their generous gift of the plasmid pHJL

Ligand-dependent active-site closure revealed in the crystal structure of Mycobacterium tuberculosis MenB complexed with product analogues

Menaquinone biosynthesis in Escherichia coli: identification of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a novel intermediate and re-evaluation of MenD activity

Molecular Basis of the General Base Catalysis of an / -Hydrolase Catalytic Triad

Nitrilotriacetic acid-modified magnetic nanoparticles as a general agent to bind histidine-tagged proteins

Phenylacetyl pepstatin inhibitors of aspartyl proteases from Streptomyces varsoviensis

Single-Turnover Kinetics Reveal a Distinct Mode of Thiamine Diphosphate-Dependent Catalysis in Vitamin K Biosynthesis

Solid-phase total synthesis and antimicrobial activities of loloatins A-D

Stabilization of the Second Oxyanion Intermediate by 1,4-Dihydroxy-2-naphthoyl-Coenzyme A Synthase of the Menaquinone Pathway: Spectroscopic Evidence of the Involvement of a Conserved Aspartic Acid ⬇️

Structural Basis for the ATP-dependent Configuration of Adenylation Active Site in Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase

Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis

Structural basis of the induced-fit mechanism of 1,4-dihydroxy-2-naphthoyl coenzyme A synthase from the crotonase fold superfamily

Substrate Recognition and Catalytic Mechanism of the Phosphate Acyltransferase PlsX from Bacillus subtilis

Substrate spectrum of tyrocidine thioesterase probed with randomized peptide N-acetylcysteamine thioesters.

Synthesis of gramicidin S and its analogues via an on-resin macrolactamization assisted by a predisposed conformation of the linear precursors.

Synthesis of tyrocidine A and its analogues by spontaneous cyclization in aqueous solution

T-Cell Epitopes in Severe Acute Respiratory Syndrome (SARS) Coronavirus Spike Protein Elicit a Specific T-Cell Immune Response in Patients Who Recover from SARS.

T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus spike protein elicit a specific T-cell immune response in patients who recover from SARS.

The biosynthesis of GDP-L-colitose: C-3 deoxygenation is catalyzed by a unique coenzyme B6-dependent enzyme

Two active site arginines are critical determinants of substrate binding and catalysis in MenD, a thiamine-dependent enzyme in menaquinone biosynthesis

Using β-Lactamase to Trigger Supramolecular Hydrogelation