List of works - David A Long

Abnormal angiogenesis in diabetic nephropathy.

scientific article published on July 2009

Aging-associated renal disease in mice is fructokinase dependent.

scientific article published on 27 July 2016

Albuminuria is associated with too few glomeruli and too much testosterone

scientific article published on 27 February 2013

Angiogenesis and autosomal dominant polycystic kidney disease.

scientific article published on 19 September 2012

Angiopoietin correlates with glomerular capillary loss in anti-glomerular basement membrane glomerulonephritis

scientific article published in June 2002

Angiopoietin-1 therapy enhances fibrosis and inflammation following folic acid-induced acute renal injury.

scientific article published on 14 May 2008

Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism.

scientific article published on 29 October 2008

Arterial "inflammaging" drives vascular calcification in children on dialysis

scientific article published on 01 March 2019

Beyond a Passive Conduit: Implications of Lymphatic Biology for Kidney Diseases

scientific article published on 15 April 2020

Blood vessels and the aging kidney

scientific article published on 22 July 2005

Circulating angiopoietin-2 is a marker for early cardiovascular disease in children on chronic dialysis

scientific article

Corticosteroid-induced kidney dysmorphogenesis is associated with deregulated expression of known cystogenic molecules, as well as Indian hedgehog

scientific article published on 9 December 2009

Diabetic Nephropathy: Perspective on Novel Molecular Mechanisms.

scientific article

Experimental long-term diabetes mellitus alters the transcriptome and biomechanical properties of the rat urinary bladder

scientific article published on 30 July 2021

Experimental short-term fetal bladder outflow obstruction: I. Morphology and cell biology associated with urinary flow impairment

scientific article published on 17 April 2006

Expression of Fraser syndrome genes in normal and polycystic murine kidneys.

scientific article published on 13 October 2011

Free 25-hydroxyvitamin-D concentrations are lower in children with renal transplant compared with chronic kidney disease

scientific article published on 22 January 2020

Generating Mutant Renal Cell Lines Using CRISPR Technologies

scientific article published on 01 January 2020

HDL in children with CKD promotes endothelial dysfunction and an abnormal vascular phenotype

scientific article

HNF1B mutations associate with hypomagnesemia and renal magnesium wasting

scientific article

Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair

scientific article

How does angiotensin II cause renal injury?

scientific article published on 16 February 2004

Human vascular smooth muscle cells express a urate transporter

scientific article

IL-10 suppresses chemokines, inflammation, and fibrosis in a model of chronic renal disease

scientific journal article

Imaging intact human organs with local resolution of cellular structures using hierarchical phase-contrast tomography

scientific article published on 04 November 2021

In vivo 3-dimensional photoacoustic imaging of the renal vasculature in preclinical rodent models.

scientific article published on 20 December 2017

Increased renal angiopoietin-1 expression in folic acid-induced nephrotoxicity in mice

scientific article published in December 2001

Kidney organoids recapitulate human basement membrane assembly in health and disease

scientific article published on 25 January 2022

Lithium induces mesenchymal-epithelial differentiation during human kidney development by activation of the Wnt signalling system

scientific article published on 7 February 2018

Loss of endogenous thymosin β4 accelerates glomerular disease.

scientific article published on 26 August 2016

Loss of nitric oxide and endothelial-derived hyperpolarizing factor-mediated responses in aging.

scientific article

Mechanistic Insights into Vascular Calcification in CKD ⬇️

scientific article published on November 8, 2012

Microarray interrogation of human metanephric mesenchymal cells highlights potentially important molecules in vivo.

scientific article published on 19 September 2006

Mutations in HPSE2 cause urofacial syndrome

scientific article

Overexpression of Circulating Soluble Nogo-B Improves Diabetic Kidney Disease by Protecting the Vasculature

scientific article published on 19 June 2019

Peritubular capillary loss after mouse acute nephrotoxicity correlates with down-regulation of vascular endothelial growth factor-A and hypoxia-inducible factor-1 alpha.

scientific article published in December 2003

Planar cell polarity and the kidney

scientific article

Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning

scientific article published on 02 September 2016

Planar cell polarity in organ formation

scientific article published on 14 July 2018

Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia

scientific article published on 11 July 2007

Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis

scientific article published on 17 June 2020

Restoring the renal microvasculature to treat chronic kidney disease

scientific article published on 7 February 2012

Selective stimulation of VEGFR2 accelerates progressive renal disease

scientific article

Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease

scientific article published on 06 December 2019

Sphingosine kinase-1: a potential mediator of renal fibrosis

scientific article published in October 2009

Targeted glomerular angiopoietin-1 therapy for early diabetic kidney disease.

scientific article published on 5 September 2013

Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4

scientific journal article

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

scientific journal article

The renal archaeologist: digging for clues in archived tissues to understand diabetic kidney disease

scientific article published on 15 February 2012

The role of thymosin-β4 in kidney disease

scientific article published on 22 June 2015

The timing of auditory sensory deficits in Norrie disease has implications for therapeutic intervention

scientific article published in 2022

Thymosin-β4: A key modifier of renal disease

scientific article published on 09 May 2018

Tissue Clearing and Deep Imaging of the Kidney Using Confocal and Two-Photon Microscopy

scientific article published on 01 January 2020

Unraveling the genetic landscape of bladder development in mice.

scientific article published on 19 March 2009

Vangl2, a planar cell polarity molecule, is implicated in irreversible and reversible kidney glomerular injury

scientific article published on 01 December 2018

Vascular Endothelial Growth Factor C for Polycystic Kidney Diseases

scientific article

Vascular endothelial growth factor administration does not improve microvascular disease in the salt-dependent phase of post-angiotensin II hypertension

scientific article published on 27 June 2006

Vascular endothelial growth factor stimulates embryonic urinary bladder development in organ culture

scientific article published on 01 July 2006

Vascular growth factors play critical roles in kidney glomeruli

scientific article published on December 2015

List of works by David A Long

Abnormal angiogenesis in diabetic nephropathy.

Aging-associated renal disease in mice is fructokinase dependent.

Albuminuria is associated with too few glomeruli and too much testosterone

Angiogenesis and autosomal dominant polycystic kidney disease.

Angiopoietin correlates with glomerular capillary loss in anti-glomerular basement membrane glomerulonephritis

Angiopoietin-1 therapy enhances fibrosis and inflammation following folic acid-induced acute renal injury.

Angiostatin overexpression is associated with an improvement in chronic kidney injury by an anti-inflammatory mechanism.

Arterial "inflammaging" drives vascular calcification in children on dialysis

Beyond a Passive Conduit: Implications of Lymphatic Biology for Kidney Diseases

Blood vessels and the aging kidney

Circulating angiopoietin-2 is a marker for early cardiovascular disease in children on chronic dialysis

Corticosteroid-induced kidney dysmorphogenesis is associated with deregulated expression of known cystogenic molecules, as well as Indian hedgehog

Diabetic Nephropathy: Perspective on Novel Molecular Mechanisms.

Experimental long-term diabetes mellitus alters the transcriptome and biomechanical properties of the rat urinary bladder

Experimental short-term fetal bladder outflow obstruction: I. Morphology and cell biology associated with urinary flow impairment

Expression of Fraser syndrome genes in normal and polycystic murine kidneys.

Free 25-hydroxyvitamin-D concentrations are lower in children with renal transplant compared with chronic kidney disease

Generating Mutant Renal Cell Lines Using CRISPR Technologies

HDL in children with CKD promotes endothelial dysfunction and an abnormal vascular phenotype

HNF1B mutations associate with hypomagnesemia and renal magnesium wasting

Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair

How does angiotensin II cause renal injury?

Human vascular smooth muscle cells express a urate transporter

IL-10 suppresses chemokines, inflammation, and fibrosis in a model of chronic renal disease

Imaging intact human organs with local resolution of cellular structures using hierarchical phase-contrast tomography

In vivo 3-dimensional photoacoustic imaging of the renal vasculature in preclinical rodent models.

Increased renal angiopoietin-1 expression in folic acid-induced nephrotoxicity in mice

Kidney organoids recapitulate human basement membrane assembly in health and disease

Lithium induces mesenchymal-epithelial differentiation during human kidney development by activation of the Wnt signalling system

Loss of endogenous thymosin β4 accelerates glomerular disease.

Loss of nitric oxide and endothelial-derived hyperpolarizing factor-mediated responses in aging.

Mechanistic Insights into Vascular Calcification in CKD ⬇️

Microarray interrogation of human metanephric mesenchymal cells highlights potentially important molecules in vivo.

Mutations in HPSE2 cause urofacial syndrome

Overexpression of Circulating Soluble Nogo-B Improves Diabetic Kidney Disease by Protecting the Vasculature

Peritubular capillary loss after mouse acute nephrotoxicity correlates with down-regulation of vascular endothelial growth factor-A and hypoxia-inducible factor-1 alpha.

Planar cell polarity and the kidney

Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning

Planar cell polarity in organ formation

Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia

Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis

Restoring the renal microvasculature to treat chronic kidney disease

Selective stimulation of VEGFR2 accelerates progressive renal disease

Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease

Sphingosine kinase-1: a potential mediator of renal fibrosis

Targeted glomerular angiopoietin-1 therapy for early diabetic kidney disease.

Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

The renal archaeologist: digging for clues in archived tissues to understand diabetic kidney disease

The role of thymosin-β4 in kidney disease

The timing of auditory sensory deficits in Norrie disease has implications for therapeutic intervention

Thymosin-β4: A key modifier of renal disease

Tissue Clearing and Deep Imaging of the Kidney Using Confocal and Two-Photon Microscopy

Unraveling the genetic landscape of bladder development in mice.

Vangl2, a planar cell polarity molecule, is implicated in irreversible and reversible kidney glomerular injury

Vascular Endothelial Growth Factor C for Polycystic Kidney Diseases

Vascular endothelial growth factor administration does not improve microvascular disease in the salt-dependent phase of post-angiotensin II hypertension

Vascular endothelial growth factor stimulates embryonic urinary bladder development in organ culture

Vascular growth factors play critical roles in kidney glomeruli