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List of works by Licia Rivoltini

A large de novo 9p21.3 deletion in a girl affected by astrocytoma and multiple melanoma

scientific article

A phase II trial of vaccination with autologous, tumor-derived heat-shock protein peptide complexes Gp96, in combination with GM-CSF and interferon-α in metastatic melanoma patients

article by Lorenzo Pilla et al published 8 October 2005 in Cancer Immunology, Immunotherapy

A systematic approach to biomarker discovery; preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers".

scientific article

A variant in FTO shows association with melanoma risk not due to BMI

scientific article

Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment.

scientific article published on 5 September 2016

Adaptive immune contexture at the tumour site and downmodulation of circulating myeloid-derived suppressor cells in the response of solitary fibrous tumour patients to anti-angiogenic therapy

scientific article

Adoptive immunotherapy of advanced melanoma patients with interleukin-2 (IL-2) and tumor-infiltrating lymphocytes selected in vitro with low doses of IL-2

scientific article published on 01 May 1993

Adoptive transfer of an anti-MART-12735-specific CD8+ T cell clone leads to immunoselection of human melanoma antigen-loss variants in SCID mice

scientific article published on 01 February 2003

Alternative activation of human plasmacytoid DCs in vitro and in melanoma lesions: involvement of LAG-3.

scientific article

Amino Acid Substitutions in the Melanoma Antigen Recognized by T Cell 1 Peptide Modulate Cytokine Responses in Melanoma-Specific T Cells

article

Antitumor activity of delimotecan against human metastatic melanoma: pharmacokinetics and molecular determinants.

scientific article

Biologic agents as modifiers of chemotherapeutic effects

scientific article published on December 1, 1991

Cancer acidity: An ultimate frontier of tumor immune escape and a novel target of immunomodulation.

scientific article published on 3 March 2017

Cancer immunotherapy with peptide-based vaccines: what have we achieved? Where are we going?

scientific article

Cannibalism of live lymphocytes by human metastatic but not primary melanoma cells

scientific article published on April 2006

Chemokine Receptor 7, A New Player in Regulating Apoptosis of CD8+ T Cells in Cancer Patients

scientific article published on 01 November 2005

Class I HLA folding and antigen presentation in beta 2-microglobulin-defective Daudi cells

scientific article

Clinical and immunologic responses in melanoma patients vaccinated with MAGE-A3-genetically modified lymphocytes

scientific article published on 13 December 2012

Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor

scientific article

Cutaneous Melanoma in Childhood and Adolescence Shows Frequent Loss of INK4A and Gain of KIT

article

Cytokines in cancer therapy.

scientific article

Cytotoxic T-lymphocyte responses in melanoma through in vitro stimulation with the Melan-A peptide analogue A27L: a qualitative analysis

article

DHCR24 gene expression is upregulated in melanoma metastases and associated to resistance to oxidative stress-induced apoptosis

scientific article

Defining the critical hurdles in cancer immunotherapy

scientific article published on 14 December 2011

Detection of mutated BRAFV600E variant in circulating DNA of stage III–IV melanoma patients

scientific article published on 01 June 2007

Development of a molecular blood-based immune signature classifier as biomarker for risks assessment in Lung Cancer screening

scientific article published in 2022

Don't run before you can walk

scientific article published on 25 September 2012

Dose-finding/phase II trial: bevacizumab, immunotherapy, and chemotherapy (BIC) in metastatic renal cell cancer (mRCC). Antitumor effects and variations of circulating T regulatory cells (Treg).

scientific article

Effect of human natural killer and gammadelta T cells on the growth of human autologous melanoma xenografts in SCID mice

scientific article published in January 2004

Effects of cyclophosphamide and IL-2 on regulatory CD4+ T cell frequency and function in melanoma patients vaccinated with HLA-class I peptides: impact on the antigen-specific T cell response

scientific article published on 16 April 2013

Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology

scientific article

Enhanced antitumour efficacy of gimatecan in combination with Bcl-2 antisense oligonucleotide in human melanoma xenografts.

scientific article

Escape strategies and reasons for failure in the interaction between tumour cells and the immune system: how can we tilt the balance towards immune-mediated cancer control?

scientific article

Exploiting liver immunity for the prevention of hepatic metastases

scientific article published on 11 June 2010

Factors, including transforming growth factor beta, released in the glioblastoma residual cavity, impair activity of adherent lymphokine-activated killer cells.

scientific article published in June 1993

Frequency of Circulating Tregs with Demethylated FOXP3 Intron 1 in Melanoma Patients Receiving Tumor Vaccines and Potentially Treg-Depleting Agents

scientific article published on 21 December 2010

Future perspectives in melanoma research. Meeting report from the "Melanoma Research: a bridge Naples-USA. Naples, December 6th-7th 2010"

scientific article published on 26 March 2011

HLA associations in the antitumor response against malignant melanoma.

scientific article published on November 1995

Heat shock proteins and their use as anticancer vaccines.

scientific article

Heat shock proteins gp96 as immunogens in cancer patients

scientific article published on 01 May 2006

Heat shock proteins: biological functions and clinical application as personalized vaccines for human cancer.

scientific article published on 19 December 2003

Hepatocellular Carcinoma is Associated with Gut Microbiota Profile and Inflammation in Non-Alcoholic Fatty Liver Disease.

scientific article

Heterogeneous phenotype of human melanoma cells with in vitro and in vivo features of tumor-initiating cells

scientific article published on 8 April 2010

High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients

scientific article

Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals

scientific article

Human Colorectal Cancer Cells Induce T-Cell Death Through Release of Proapoptotic Microvesicles: Role in Immune Escape

scientific article published on 01 June 2005

Human plasmacytoid dendritic cells interact with gp96 via CD91 and regulate inflammatory responses

scientific article

Human tumor-derived heat shock protein 96 mediates in vitro activation and in vivo expansion of melanoma- and colon carcinoma-specific T cells.

scientific article published on October 2003

Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-beta-mediated suppressive activity on T lymphocytes

scientific article published on September 2006

IFNalpha-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells

scientific article

Identification of MET and SRC activation in melanoma cell lines showing primary resistance to PLX4032.

scientific article published on December 2011

Identification of a New Subset of Myeloid Suppressor Cells in Peripheral Blood of Melanoma Patients With Modulation by a Granulocyte-Macrophage Colony-Stimulation Factor–Based Antitumor Vaccine

scientific article published on 01 June 2007

Immune cells in the melanoma microenvironment hold information for prediction of the risk of recurrence and response to treatment

scientific article published on 10 June 2014

Immune response markers in sentinel nodes may predict melanoma progression

scientific article

Immune surveillance properties of human NK cell-derived exosomes.

scientific article published on 17 August 2012

Immunity to cancer: attack and escape in T lymphocyte-tumor cell interaction

scientific article

Immunization of stage IV melanoma patients with Melan-A/MART-1 and gp100 peptides plus IFN-alpha results in the activation of specific CD8(+) T cells and monocyte/dendritic cell precursors.

scientific article published in May 2006

Immuno-oncology in head and neck squamous cell cancers: News from clinical trials, emerging predictive factors and unmet needs.

scientific article published on 20 March 2018

Immunogenicity of the ALLAVGATK (gp10017 – 25) peptide in HLA-A3.1 melanoma patients

scientific article published on April 1, 1998

Immunomodulatory Factors Control the Fate of Melanoma Tumor Initiating Cells.

scientific article published on 14 June 2016

Immunotherapy of melanoma

scientific article published on 01 December 2003

In Reply

In vitro anti-tumor activity of eosinophils from cancer patients treated with subcutaneous administration of interleukin 2. Role of interleukin 5

scientific article published on 01 April 1993

Increased susceptibility to lymphokine activated killer (LAK) lysis of relapsing vs. newly diagnosed acute leukemic cells without changes in drug resistance or in the expression of adhesion molecules.

scientific article

Induction of both CD8+ and CD4+ T-cell-mediated responses in colorectal cancer patients by colon antigen-1.

scientific article published on 30 October 2008

Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles.

scientific article

Interferon-activated neutrophils store a TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) intracellular pool that is readily mobilizable following exposure to proinflammatory mediators

scientific article published on 21 October 2005

Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): an open-label, single-arm phase 2 trial

scientific article

LAG-3 expression defines a subset of CD4(+)CD25(high)Foxp3(+) regulatory T cells that are expanded at tumor sites

scientific article

Limited induction of tumor cross-reactive T cells without a measurable clinical benefit in early melanoma patients vaccinated with human leukocyte antigen class I-modified peptides

scientific article published on 2 October 2012

Loco-regional immunotherapy with recombinant interleukin-2 and adherent lymphokine-activated killer cells (A-LAK) in recurrent glioblastoma patients.

scientific article published in September 1994

Longitudinal study of recurrent metastatic melanoma cell lines underscores the individuality of cancer biology.

scientific article

Low TCR avidity and lack of tumor cell recognition in CD8+ T cells primed with the CEA-analogue CAP1-6D peptide

scientific article published on 13 June 2007

Lymphocyte activation gene-3 (LAG-3, CD223) in plasmacytoid dendritic cells (pDCs): a molecular target for the restoration of active antitumor immunity

scientific article published on November 2014

MIAQuant, a novel system for automatic segmentation, measurement, and localization comparison of different biomarkers from serialized histological slices.

scientific article published in October 2017

Melan-A/MART-1 immunity in a EWS-ATF1 translocated clear cell sarcoma patient treated with sunitinib: a case report

scientific article

Melanoma cells homing to the brain: an in vitro model

scientific article published on 26 January 2015

Melanoma immunology: past, present and future.

scientific article published on March 2007

Melanoma-specific CD4+ T lymphocytes recognize human melanoma antigens processed and presented by Epstein-Barr virus-transformed B cells

scientific article

Modified peptides in anti-cancer vaccines: are we eventually improving anti-tumour immunity?

scientific article published on 08 November 2008

Modulation of microenvironment acidity reverses anergy in human and murine tumor-infiltrating T lymphocytes.

scientific article

Modulation of multidrug resistance by verapamil or mdr1 anti-sense oligodeoxynucleotide does not change the high susceptibility to lymphokine-activated killers in mdr-resistant human carcinoma (LoVo) line.

scientific article published in October 1990

Modulation of the myeloid compartment of the immune system by angiogenic- and kinase inhibitor-targeted anti-cancer therapies.

scientific article published on 04 July 2014

Molecular and functional bases of self-antigen recognition in long-term persistent melanocyte-specific CD8+ T cells in one vitiligo patient

scientific article published in August 2003

Monitoring the Frequency and Function of Regulatory T Cells and Summary of the Approaches Currently Used to Inhibit Regulatory T Cells in Cancer Patients

scientific article published on 01 January 2014

More insights into the immunosuppressive potential of tumor exosomes.

scientific article published on 30 October 2008

Multipeptide vaccination in cancer patients.

scientific article published on August 2009

Murine granulocytes control human tumor growth in SCID mice.

scientific article published in August 2000

NKG2D-mediated antitumor activity by tumor-infiltrating lymphocytes and antigen-specific T-cell clones isolated from melanoma patients

scientific article published on December 2007

Natural Killer andNK-LikeT-Cell Activation in Colorectal Carcinoma Patients Treated with Autologous Tumor-Derived Heat Shock Protein 96

scientific article published on 01 May 2005

Neuropsychological and neurophysiological assessment of the central effects of interleukin-2 administration

scientific article published on 01 January 1993

New common variants affecting susceptibility to basal cell carcinoma

scientific article

Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b

scientific article published on 14 December 2015

Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients

scientific article

Phenotypic and functional analysis of lymphocytes infiltrating paediatric tumours, with a characterization of the tumour phenotype

article

Potent phagocytic activity discriminates metastatic and primary human malignant melanomas: a key role of ezrin

scientific article published on November 2003

Potential role of HER2-overexpressing exosomes in countering trastuzumab-based therapy

scientific article published on February 2012

Promoter methylation of aminopeptidase N/CD13 in malignant melanoma.

scientific article

Proton dynamics in cancer

scientific article published on 15 June 2010

Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells

scientific article

Quantitation of antigen-reactive T cells in peripheral blood by IFNgamma-ELISPOT assay and chromium-release assay: a four-centre comparative trial

scientific article published in October 2000

Recent advances on the role of tumor exosomes in immunosuppression and disease progression

scientific article published on 19 February 2012

Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers

scientific article

Reconstitution of human telomerase reverse transcriptase expression rescues colorectal carcinoma cells from in vitro senescence: evidence against immortality as a constitutive trait of tumor cells

scientific article published in March 2005

Response to Griewank and Bastian

Role of cross-talk between IFN-alpha-induced monocyte-derived dendritic cells and NK cells in priming CD8+ T cell responses against human tumor antigens.

scientific article published on May 2004

Safety and immunogenicity of the PRAME cancer immunotherapeutic in metastatic melanoma: results of a phase I dose escalation study.

scientific article

Salivary Cytokine Levels and Oral Mucositis in Head and Neck Cancer Patients Treated With Chemotherapy and Radiation Therapy

scientific article published on 6 September 2016

Simultaneous transduction of B7-1 and IL-2 genes into human melanoma cells to be used as vaccine: enhancement of stimulatory activity for autologous and allogeneic lymphocytes

article

Soluble human LAG-3 molecule amplifies the in vitro generation of type 1 tumor-specific immunity

scientific article

Spheres of Influence in Cancer Stem Cell Biology

scientific article published on 21 October 2010

Structured myeloid cells and anti-angiogenic therapy in alveolar soft part sarcoma.

scientific article published on 27 September 2013

Susceptibility of human and murine drug-resistant tumor cells to the lytic activity of rIL2-activated lymphocytes (LAK).

scientific article published on December 1988

T-cell recognition of melanoma antigens and its therapeutic applications

scientific article published on January 1, 1997

TNF-Related Apoptosis-Inducing Ligand (TRAIL)-Armed Exosomes Deliver Proapoptotic Signals to Tumor Site

scientific article published on 4 March 2016

Targeting Immune Regulatory Networks to Counteract Immune Suppression in Cancer

scientific article

The Detection and Biological Activity of Human Antibodies to IL-2 in Normal Donors

scientific article published on 01 November 1993

The acidity of the tumor microenvironment is a mechanism of immune escape that can be overcome by proton pump inhibitors.

scientific article published on January 2013

The neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios predict efficacy of platinum-based chemotherapy in patients with metastatic triple negative breast cancer.

scientific article

Transcriptional profiling of melanoma sentinel nodes identify patients with poor outcome and reveal an association of CD30(+) T lymphocytes with progression

scientific article published on January 2014

Tumor Exosomes and Their Impact on Immunity and Cancer Progression

Tumor necrosis factor-alpha induces coordinated changes in major histocompatibility class I presentation pathway, resulting in increased stability of class I complexes at the cell surface

scientific article published in August 2001

Tumor-Derived Exosomes as Dendritic Cell Modulators

Tumor-released microvesicles as vehicles of immunosuppression.

scientific article

Tumour-released exosomes and their implications in cancer immunity.

scientific article published on 12 October 2007

Universal and Stemness-Related Tumor Antigens: Potential Use in Cancer Immunotherapy

scientific article published on 01 October 2007

Vaccination of Metastatic Melanoma Patients With Autologous Tumor-Derived Heat Shock Protein gp96-Peptide Complexes: Clinical and Immunologic Findings

scientific article published on 01 October 2002

Vaccination of melanoma patients with interleukin 4 gene-transduced allogeneic melanoma cells

scientific article published on December 1999

Vaccination therapy in prostate cancer.

scientific article published on 10 October 2006

Vaccination: role in metastatic melanoma.

scientific article published on August 2006

beta2-Microglobulin mutations, HLA class I antigen loss, and tumor progression in melanoma.

scientific article published on June 1998

microRNA Expression in Sentinel Nodes from Progressing Melanoma Patients Identifies Networks Associated with Dysfunctional Immune Response

scientific article published on 14 December 2016

pH regulators to target the tumor immune microenvironment in human hepatocellular carcinoma.

scientific article

pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity

scientific article published on July 2010