List of works - Adriano Angelucci

"Vessels in the Storm": Searching for Prognostic and Predictive Angiogenic Factors in Colorectal Cancer.

scientific article

A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors.

scientific article published on March 2013

Additive antitumor effects of the epidermal growth factor receptor tyrosine kinase inhibitor, gefitinib (Iressa), and the nonsteroidal antiandrogen, bicalutamide (Casodex), in prostate cancer cells in vitro.

scientific article published on July 2005

An overview of the effect of linoleic and conjugated-linoleic acids on the growth of several human tumor cell lines

scientific article published on December 2004

Antiproliferative and pro-apoptotic effects afforded by novel Src-kinase inhibitors in human neuroblastoma cells

scientific article published on 4 November 2010

Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells

scientific article

Arachidonic acid modulates the crosstalk between prostate carcinoma and bone stromal cells

scientific article

Body mass index represents a good predictor of vitamin D status in women independently from age.

scientific article published on 2 March 2018

Bombesin-dependent pro-MMP-9 activation in prostatic cancer cells requires beta1 integrin engagement

scientific article published on October 2002

Bone-targeted doxorubicin-loaded nanoparticles as a tool for the treatment of skeletal metastases.

scientific article published on November 2010

Cancer multitarget pharmacology in prostate tumors: tyrosine kinase inhibitors and beyond.

scientific article published on January 2011

Cellular and Molecular Mechanisms Mediated by recPrP Involved in the Neuronal Differentiation Process of Mesenchymal Stem Cells

scientific article published on 16 January 2019

Chemically stable inhibitors of 14-3-3 protein-protein interactions derived from BV02

scientific article published on 01 December 2019

Combining X-ray crystallography and molecular modeling toward the optimization of pyrazolo[3,4-d]pyrimidines as potent c-Src inhibitors active in vivo against neuroblastoma

scientific article

Crocetin Extracted from Saffron Shows Antitumor Effects in Models of Human Glioblastoma

scientific article published on 09 January 2020

Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant.

scientific article

Detection of telomerase activity in prostate massage samples improves differentiating prostate cancer from benign prostatic hyperplasia

scientific article published on 29 January 2004

Effects of 5 alpha reductase inhibitors on androgen-dependent human prostatic carcinoma cells.

scientific article published on 14 January 2005

Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases.

scientific article

Effects of dutasteride on prostate carcinoma primary cultures: a comparative study with finasteride and MK386.

scientific article published on 22 May 2008

EphA2 induces metastatic growth regulating amoeboid motility and clonogenic potential in prostate carcinoma cells

scientific article published on 4 January 2011

Epidermal growth factor modulates prostate cancer cell invasiveness regulating urokinase-type plasminogen activator activity. EGF-receptor inhibition may prevent tumor cell dissemination.

scientific article

Extracellular Vesicles: New Endogenous Shuttles for miRNAs in Cancer Diagnosis and Therapy?

scientific article published on 04 September 2020

Hypoxia Induces DPSC Differentiation versus a Neurogenic Phenotype by the Paracrine Mechanism

scientific article published on 03 May 2022

Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction

scientific article published on 20 March 2020

Identification of a novel pyrazolo[3,4-d]pyrimidine able to inhibit cell proliferation of a human osteogenic sarcoma in vitro and in a xenograft model in mice

scientific article

Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells.

scientific article

Increased expression of a set of genes enriched in oxygen binding function discloses a predisposition of breast cancer bone metastases to generate metastasis spread in multiple organs

scientific article

Indolyl-pyrrolone as a new scaffold for Pim1 inhibitors

scientific article

Inhibition of angiogenesis mediated by extremely low-frequency magnetic fields (ELF-MFs)

scientific article

Inhibition of protein kinase c-Src reduces the incidence of breast cancer metastases and increases survival in mice: implications for therapy

scientific article published on 20 April 2006

Kinase-dependent and -independent roles of EphA2 in the regulation of prostate cancer invasion and metastasis

scientific article

Leptin contributes to long-term stabilization of HIF-1α in cancer cells subjected to oxygen limiting conditions

scientific article published on 17 March 2016

Mechanisms underlying the anti-tumoral effects of Citrus Bergamia juice

scientific article published in 2013

Molecular aspects of gefitinib antiproliferative and pro-apoptotic effects in PTEN-positive and PTEN-negative prostate cancer cell lines.

scientific article published on December 2005

Molecular pathogenesis of bone metastases in breast cancer: Proven and emerging therapeutic targets

scientific article

Neuroendocrine transdifferentiation induced by VPA is mediated by PPARgamma activation and confers resistance to antiblastic therapy in prostate carcinoma

scientific article published on May 2008

New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells

scientific article

Optimization of Aminoimidazole Derivatives as Src Family Kinase Inhibitors

scientific article published on 17 September 2018

Osteoblast-derived TGF-beta1 modulates matrix degrading protease expression and activity in prostate cancer cells

scientific article published on February 2000

Osteoblast-derived TGFbeta-1 modulates matrix degrading protease expression and activity in prostate cancer cells

scientific article published on 01 June 2000

Osteopontin enhances the cell proliferation induced by the epidermal growth factor in human prostate cancer cells

scientific article published on May 2004

Osteopontin modulates prostate carcinoma invasive capacity through RGD-dependent upregulation of plasminogen activators

scientific article

Plasma brain-derived neurotrophic factor in earthquake survivors with full and partial post-traumatic stress disorder

scientific article published in July 2013

Proline/arginine-rich end leucine-rich repeat protein N-terminus is a novel osteoclast antagonist that counteracts bone loss

scientific article published on September 2013

Prostate cancer and bone: the elective affinities.

scientific article

Prostate cancer cell proliferation is strongly reduced by the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in vitro on human cell lines and primary cultures

scientific article published on 4 March 2003

Pyrazolo[3,4-d]pyrimidine Prodrugs: Strategic Optimization of the Aqueous Solubility of Dual Src/Abl Inhibitors

scientific article published on 20 May 2013

Pyrazolo[3,4-d]pyrimidines c-Src inhibitors reduce epidermal growth factor-induced migration in prostate cancer cells

scientific article published on 14 September 2006

Receptor activator of NF-kappaB ligand enhances breast cancer-induced osteolytic lesions through upregulation of extracellular matrix metalloproteinase inducer/CD147.

scientific article published on 14 July 2010

Reduction of glutamate levels in HIV-infected subjects treated with acetylcarnitine

scientific article published on 01 January 1999

Roles of metalloproteases in metastatic niche

scientific article

Serum 25(OH)D seasonality in urologic patients from central Italy

scientific article published on 9 July 2016

Src Family Kinases as Therapeutic Targets in Advanced Solid Tumors: What We Have Learned so Far

scientific article published on 02 June 2020

Src inhibition potentiates antitumoral effect of paclitaxel by blocking tumor-induced angiogenesis

scientific article published on 14 August 2014

Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors

scientific article published on 29 April 2015

Suberoylanilide hydroxamic acid partly reverses resistance to paclitaxel in human ovarian cancer cell lines

scientific article published on 9 September 2010

Suppression of EGF-R signaling reduces the incidence of prostate cancer metastasis in nude mice

scientific article published on March 2006

Surgical and biologic outcomes after neoadjuvant bicalutamide treatment in prostate cancer

scientific article published in October 2007

Tamsulosin treatment increases clinical success rate of single extracorporeal shock wave lithotripsy of renal stones

scientific article published in July 2005

Targeting ERBB receptors to inhibit metastasis: old hopes and new certainties

scientific article published on February 2009

Targeting Tyrosine Kinases in Cancer: Lessons for an Effective Targeted Therapy in the Clinic

scientific article published on 06 April 2019

Targeting vascular cell migration as a strategy for blocking angiogenesis: the central role of focal adhesion protein tyrosine kinase family.

scientific article published on January 2007

Tau oligomers accumulation sensitizes prostate cancer cells to docetaxel treatment

scientific article published on 02 April 2021

The growth arrest and downregulation of c-myc transcription induced by ceramide are related events dependent on p21 induction, Rb underphosphorylation and E2F sequestering

scientific article published on May 1998

Tissue print of prostate biopsy: a novel tool in the diagnostic procedure of prostate cancer

scientific article published on 13 April 2011

Tumor-stroma metabolic relationship based on lactate shuttle can sustain prostate cancer progression

scientific article

Valproic acid induces apoptosis in prostate carcinoma cell lines by activation of multiple death pathways

scientific article published on November 2006

Vesicle-associated urokinase plasminogen activator promotes invasion in prostate cancer cell lines

scientific article published on January 2000

List of works by Adriano Angelucci

"Vessels in the Storm": Searching for Prognostic and Predictive Angiogenic Factors in Colorectal Cancer.

A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors.

Additive antitumor effects of the epidermal growth factor receptor tyrosine kinase inhibitor, gefitinib (Iressa), and the nonsteroidal antiandrogen, bicalutamide (Casodex), in prostate cancer cells in vitro.

An overview of the effect of linoleic and conjugated-linoleic acids on the growth of several human tumor cell lines

Antiproliferative and pro-apoptotic effects afforded by novel Src-kinase inhibitors in human neuroblastoma cells

Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells

Arachidonic acid modulates the crosstalk between prostate carcinoma and bone stromal cells

Body mass index represents a good predictor of vitamin D status in women independently from age.

Bombesin-dependent pro-MMP-9 activation in prostatic cancer cells requires beta1 integrin engagement

Bone-targeted doxorubicin-loaded nanoparticles as a tool for the treatment of skeletal metastases.

Cancer multitarget pharmacology in prostate tumors: tyrosine kinase inhibitors and beyond.

Cellular and Molecular Mechanisms Mediated by recPrP Involved in the Neuronal Differentiation Process of Mesenchymal Stem Cells

Chemically stable inhibitors of 14-3-3 protein-protein interactions derived from BV02

Combining X-ray crystallography and molecular modeling toward the optimization of pyrazolo[3,4-d]pyrimidines as potent c-Src inhibitors active in vivo against neuroblastoma

Crocetin Extracted from Saffron Shows Antitumor Effects in Models of Human Glioblastoma

Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant.

Detection of telomerase activity in prostate massage samples improves differentiating prostate cancer from benign prostatic hyperplasia

Effects of 5 alpha reductase inhibitors on androgen-dependent human prostatic carcinoma cells.

Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases.

Effects of dutasteride on prostate carcinoma primary cultures: a comparative study with finasteride and MK386.

EphA2 induces metastatic growth regulating amoeboid motility and clonogenic potential in prostate carcinoma cells

Epidermal growth factor modulates prostate cancer cell invasiveness regulating urokinase-type plasminogen activator activity. EGF-receptor inhibition may prevent tumor cell dissemination.

Extracellular Vesicles: New Endogenous Shuttles for miRNAs in Cancer Diagnosis and Therapy?

Hypoxia Induces DPSC Differentiation versus a Neurogenic Phenotype by the Paracrine Mechanism

Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction

Identification of a novel pyrazolo[3,4-d]pyrimidine able to inhibit cell proliferation of a human osteogenic sarcoma in vitro and in a xenograft model in mice

Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells.

Increased expression of a set of genes enriched in oxygen binding function discloses a predisposition of breast cancer bone metastases to generate metastasis spread in multiple organs

Indolyl-pyrrolone as a new scaffold for Pim1 inhibitors

Inhibition of angiogenesis mediated by extremely low-frequency magnetic fields (ELF-MFs)

Inhibition of protein kinase c-Src reduces the incidence of breast cancer metastases and increases survival in mice: implications for therapy

Kinase-dependent and -independent roles of EphA2 in the regulation of prostate cancer invasion and metastasis

Leptin contributes to long-term stabilization of HIF-1α in cancer cells subjected to oxygen limiting conditions

Mechanisms underlying the anti-tumoral effects of Citrus Bergamia juice

Molecular aspects of gefitinib antiproliferative and pro-apoptotic effects in PTEN-positive and PTEN-negative prostate cancer cell lines.

Molecular pathogenesis of bone metastases in breast cancer: Proven and emerging therapeutic targets

Neuroendocrine transdifferentiation induced by VPA is mediated by PPARgamma activation and confers resistance to antiblastic therapy in prostate carcinoma

New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells

Optimization of Aminoimidazole Derivatives as Src Family Kinase Inhibitors

Osteoblast-derived TGF-beta1 modulates matrix degrading protease expression and activity in prostate cancer cells

Osteoblast-derived TGFbeta-1 modulates matrix degrading protease expression and activity in prostate cancer cells

Osteopontin enhances the cell proliferation induced by the epidermal growth factor in human prostate cancer cells

Osteopontin modulates prostate carcinoma invasive capacity through RGD-dependent upregulation of plasminogen activators

Plasma brain-derived neurotrophic factor in earthquake survivors with full and partial post-traumatic stress disorder

Proline/arginine-rich end leucine-rich repeat protein N-terminus is a novel osteoclast antagonist that counteracts bone loss

Prostate cancer and bone: the elective affinities.

Prostate cancer cell proliferation is strongly reduced by the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in vitro on human cell lines and primary cultures

Pyrazolo[3,4-d]pyrimidine Prodrugs: Strategic Optimization of the Aqueous Solubility of Dual Src/Abl Inhibitors

Pyrazolo[3,4-d]pyrimidines c-Src inhibitors reduce epidermal growth factor-induced migration in prostate cancer cells

Receptor activator of NF-kappaB ligand enhances breast cancer-induced osteolytic lesions through upregulation of extracellular matrix metalloproteinase inducer/CD147.

Reduction of glutamate levels in HIV-infected subjects treated with acetylcarnitine

Roles of metalloproteases in metastatic niche

Serum 25(OH)D seasonality in urologic patients from central Italy

Src Family Kinases as Therapeutic Targets in Advanced Solid Tumors: What We Have Learned so Far

Src inhibition potentiates antitumoral effect of paclitaxel by blocking tumor-induced angiogenesis

Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors

Suberoylanilide hydroxamic acid partly reverses resistance to paclitaxel in human ovarian cancer cell lines

Suppression of EGF-R signaling reduces the incidence of prostate cancer metastasis in nude mice

Surgical and biologic outcomes after neoadjuvant bicalutamide treatment in prostate cancer

Tamsulosin treatment increases clinical success rate of single extracorporeal shock wave lithotripsy of renal stones

Targeting ERBB receptors to inhibit metastasis: old hopes and new certainties

Targeting Tyrosine Kinases in Cancer: Lessons for an Effective Targeted Therapy in the Clinic

Targeting vascular cell migration as a strategy for blocking angiogenesis: the central role of focal adhesion protein tyrosine kinase family.

Tau oligomers accumulation sensitizes prostate cancer cells to docetaxel treatment

The growth arrest and downregulation of c-myc transcription induced by ceramide are related events dependent on p21 induction, Rb underphosphorylation and E2F sequestering

Tissue print of prostate biopsy: a novel tool in the diagnostic procedure of prostate cancer

Tumor-stroma metabolic relationship based on lactate shuttle can sustain prostate cancer progression

Valproic acid induces apoptosis in prostate carcinoma cell lines by activation of multiple death pathways

Vesicle-associated urokinase plasminogen activator promotes invasion in prostate cancer cell lines