List of works by Kam W. Leong

3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures

scientific article

A CRISPR/Cas9-based system for reprogramming cell lineage specification.

scientific article

A Versatile Nonviral Delivery System for Multiplex Gene-Editing in the Liver

scientific article published on 14 October 2020

A dual-functional fibrous scaffold enhances P450 activity of cultured primary rat hepatocytes

scientific article published on 25 May 2007

A mineralizing pool of Gli1-expressing progenitors builds the tendon enthesis and demonstrates therapeutic potential

scientific article published in December 2022

A multifunctional mesoporous silica–gold nanocluster hybrid platform for selective breast cancer cell detection using a catalytic amplification-based colorimetric assay

scientific article published in 2019

A new nerve guide conduit material composed of a biodegradable poly(phosphoester).

scientific article

A nonlinear hyperelastic mixture theory model for anisotropy, transport, and swelling of annulus fibrosus.

scientific article published in January 2004

A novel biodegradable gene carrier based on polyphosphoester

scientific article

A novel immune competent murine hypertrophic scar contracture model: a tool to elucidate disease mechanism and develop new therapies

scientific article

A programmable microenvironment for cellular studies via microfluidics-generated double emulsions.

scientific article published on 21 March 2013

A robust strategy for negative selection of Cre-loxP recombination-based excision of transgenes in induced pluripotent stem cells

scientific article

A versatile platform for surface modification of microfluidic droplets

scientific article

Adhesion contact dynamics of HepG2 cells on galactose-immobilized substrates

scientific article

Adhesion contact dynamics of primary hepatocytes on poly(ethylene terephthalate) surface.

scientific article published in March 2005

Aligned Protein-Polymer Composite Fibers Enhance Nerve Regeneration: A Potential Tissue-Engineering Platform

scientific article published on January 2007

Aligned core-shell nanofibers delivering bioactive proteins.

scientific article published in December 2006

An implantable blood clot-based immune niche for enhanced cancer vaccination

scientific article published on 25 September 2020

Antigen-specific induction of peripheral T cell tolerance in vivo by codelivery of DNA vectors encoding antigen and Fas ligand

scientific article published on April 2000

Aptamer nanomedicine for cancer therapeutics: barriers and potential for translation.

scientific article

Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery.

scientific article published on 04 September 2009

Bioadhesive characterization of poly(methylidene malonate 2.12) microparticle on model extracellular matrix

scientific article published on August 2004

Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site

scientific article

Biodegradable and photocrosslinkable polyphosphoester hydrogel

scientific article published on 24 August 2005

Biodegradable poly(terephthalate-co-phosphate)s: synthesis, characterization and drug-release properties

scientific article published on January 2005

Biodegradable polyphosphoester micelles for gene delivery.

scientific article published on August 2004

Bioerodible polyanhydrides as drug-carrier matrices. I: Characterization, degradation, and release characteristics

scientific article published in October 1985

Bioerodible polyanhydrides as drug-carrier matrices. II. Biocompatibility and chemical reactivity

scientific article published in January 1986

Bioinspired Diselenide-Bridged Mesoporous Silica Nanoparticles for Dual-Responsive Protein Delivery

scientific article published on 28 May 2018

Biomaterials approach to expand and direct differentiation of stem cells

scientific article

Biomimetic Diselenide-Bridged Mesoporous Organosilica Nanoparticles as an X-ray-Responsive Biodegradable Carrier for Chemo-Immunotherapy

scientific article published on 09 November 2020

Bioreactor model of neuromuscular junction with electrical stimulation for pharmacological potency testing

scientific article published on 23 November 2017

Biostable electrospun microfibrous scaffolds mitigate hypertrophic scar contraction in an immune-competent murine model

scientific article published on 17 December 2015

Block-selected molecular recognition and formation of polypseudorotaxanes between poly(propylene oxide)-poly(ethylene oxide)-poly(propylene oxide) triblock copolymers and alpha-cyclodextrin

scientific article published in January 2003

Block-selected molecular recognition and formation of polypseudorotaxanes between poly(propylene oxide)-poly(ethylene oxide)-poly(propylene oxide) triblock copolymers and alpha-cyclodextrin

scientific article

CNS gene transfer mediated by a novel controlled release system based on DNA complexes of degradable polycation PPE-EA: a comparison with polyethylenimine/DNA complexes

scientific article published on January 2004

CRISPR/Cas9-mediated mutagenesis to validate the synergy between PARP1 inhibition and chemotherapy in BRCA1-mutated breast cancer cells

scientific article published on 02 January 2020

Can microfluidics address biomanufacturing challenges in drug/gene/cell therapies?

scientific article

Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells.

scientific article

Cationic nanoparticle as an inhibitor of cell-free DNA-induced inflammation

scientific article published in Nature Communications

Cell-laden microfluidic microgels for tissue regeneration

scientific article published on 31 October 2016

Chaperoning vaccines

scientific article published in July 2010

Characterization of topographical effects on macrophage behavior in a foreign body response model

scientific article

Chemical modification of collagen improves glycosaminoglycan retention of their co-precipitates

scientific article published in January 2013

Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice

scientific article

Chitosan nanoparticles for oral drug and gene delivery

scientific article published on January 2006

Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency

scientific article

Chitosan-DNA nanoparticles delivered by intrabiliary infusion enhance liver-targeted gene delivery

scientific article published on January 2006

Chitosan-g-PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions

scientific article published on April 2006

Co-culture of Umbilical Cord Blood CD34þ Cells with Human Mesenchymal Stem Cells

scientific article published in August 2006

Coculture of mesenchymal stem cells and respiratory epithelial cells to engineer a human composite respiratory mucosa

scientific article published in September 2004

Codelivery of CRISPR-Cas9 and chlorin e6 for spatially controlled tumor-specific gene editing with synergistic drug effects

scientific article published on 15 July 2020

Collagen-based fibrous scaffold for spatial organization of encapsulated and seeded human mesenchymal stem cells.

scientific article

Combining QD-FRET and microfluidics to monitor DNA nanocomplex self-assembly in real-time

scientific article published on 26 August 2009

Comparative study of nanoparticle-mediated transfection in different GI epithelium co-culture models

scientific article published on 3 February 2012

Comparison of mixed and lamellar coculture spatial arrangements for tissue engineering capillary networks in vitro

scientific article published on 21 November 2012

Controlled delivery of antigens and adjuvants in vaccine development

scientific article published on December 1996

Controlled gene delivery by DNA-gelatin nanospheres

scientific article published on August 1998

Controlled local delivery of interleukin-2 by biodegradable polymers protects animals from experimental brain tumors and liver tumors.

scientific article

Controlled release from fibers of polyelectrolyte complexes.

scientific article published on 7 April 2005

Controlled release of heparin from poly(epsilon-caprolactone) electrospun fibers

scientific article published on 21 November 2005

Core Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell Lineage

scientific article

Coupling spatial segregation with synthetic circuits to control bacterial survival

scientific article published on 29 February 2016

Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate

scientific article

DNA-polycation nanospheres as non-viral gene delivery vehicles

scientific article published on April 1998

Deformation of stem cell nuclei by nanotopographical cues

scientific article

Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing

scientific article

Design of polyphosphoester-DNA nanoparticles for non-viral gene delivery.

scientific article

Designing zonal organization into tissue-engineered cartilage

scientific article published in February 2007

Detection of single enzymatic events in rare or single cells using microfluidics

scientific article published on 28 September 2011

Deterministic transfection drives efficient nonviral reprogramming and uncovers reprogramming barriers

scientific article published on 19 December 2015

Development of bioabsorbable glass fibres

scientific article published in October 1994

Development of universal antidotes to control aptamer activity.

scientific article

Differentiation of mouse induced pluripotent stem cells (iPSCs) into nucleus pulposus-like cells in vitro

scientific article (publication date: 2013)

Diverse Applications of Nanomedicine

scientific article published on 14 March 2017

Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics

scientific article

Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing Plasmodium parasites based on enzyme activity measurement

scientific article

Dual-sensitive micellar nanoparticles regulate DNA unpacking and enhance gene-delivery efficiency.

scientific article

Dynamic and static light scattering studies on self-aggregation behavior of biodegradable amphiphilic poly(ethylene oxide)-poly[(R)-3-hydroxybutyrate]-poly(ethylene oxide) triblock copolymers in aqueous solution

scientific article

Dynamic control and quantification of bacterial population dynamics in droplets

scientific article published on 19 May 2015

Dynamic topographical control of mesenchymal stem cells by culture on responsive poly(ε-caprolactone) surfaces

scientific article published on 30 May 2011

Dynamics of smooth muscle cell deadhesion from thermosensitive hydroxybutyl chitosan.

scientific article published on 08 December 2006

Editorial

scientific article published on 08 November 2014

Effect of Electromechanical Stimulation on the Maturation of Myotubes on Aligned Electrospun Fibers

scientific article published on September 2008

Effect of side-chain structures on gene transfer efficiency of biodegradable cationic polyphosphoesters.

scientific article published in October 2003

Effects of nanoimprinted patterns in tissue-culture polystyrene on cell behavior.

scientific article published on November 2005

Effects of topographical and mechanical property alterations induced by oxygen plasma modification on stem cell behavior

scientific article published on 20 September 2012

Efficacy of engineered FVIII-producing skeletal muscle enhanced by growth factor-releasing co-axial electrospun fibers

scientific article published on 16 November 2010

Efficacy of paclitaxel released from bio-adhesive polymer microspheres on model superficial bladder cancer

scientific article published on March 2004

Efficient One-Step Production of Microencapsulated Hepatocyte Spheroids with Enhanced Functions.

scientific article published on April 2016

Electrohydrodynamics: A facile technique to fabricate drug delivery systems

scientific article published on 03 August 2009

Electrosprayed core–shell microspheres for protein delivery

scientific article published in 2010

Emerging links between surface nanotechnology and endocytosis: impact on nonviral gene delivery

scientific article published on December 2010

Encapsulation of biologics in self-assembled fibers as biostructural units for tissue engineering

scientific article published in December 2004

Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain

scientific article published on 16 June 2020

Engineered Mesenchymal Stem Cell/Nanomedicine Spheroid as an Active Drug Delivery Platform for Combinational Glioblastoma Therapy

scientific article published on 21 February 2019

Engineering Cell Membrane-Based Nanotherapeutics to Target Inflammation

scientific article published on 22 May 2019

Engineering liver microtissues for disease modeling and regenerative medicine

scientific article published on 19 February 2020

Engineering mesenchymal stem cells for regenerative medicine and drug delivery

scientific article

Engineering microenvironment for expansion of sensitive anchorage-dependent mammalian cells

scientific article published in September 2005

Engineering of a microfluidic cell culture platform embedded with nanoscale features.

scientific article published on 25 March 2011

Engineering of a sugar-derivatized porous network for hepatocyte culture

scientific article published in January 1996

Engineering strategies to enhance nanoparticle-mediated oral delivery.

scientific article published on January 2008

Enhanced extracellular matrix production and differentiation of human embryonic germ cell derivatives in biodegradable poly(epsilon-caprolactone-co-ethyl ethylene phosphate) scaffold.

scientific article published on 18 May 2006

Enhanced gene expression in mouse muscle by sustained release of plasmid DNA using PPE-EA as a carrier.

scientific article published on September 2002

Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET

scientific article published on 22 September 2006

Evaluation of collagen and methylated collagen as gene carriers.

scientific article published on July 2004

Evaluation of hyperbranched poly(amino ester)s of amine constitutions similar to polyethylenimine for DNA delivery

scientific article

Evaluation of polyphosphates and polyphosphonates as degradable biomaterials

scientific article published in September 1991

Expanding Nanopatterned Substrates Using Stitch Technique for Nanotopographical Modulation of Cell Behavior

scientific article published on 8 December 2016

Expansion of engrafting human hematopoietic stem/progenitor cells in three-dimensional scaffolds with surface-immobilized fibronectin.

scientific article published on September 2006

Fabrication of Controlled Release Biodegradable Foams by Phase Separation

scientific article published in March 1995

Fabrication of poly(phosphoester) nerve guides by immersion precipitation and the control of porosity

scientific article

Fibroblast and hepatocyte behavior on synthetic polymer surfaces

scientific article published on June 1991

Flash Fabrication of Orally Targeted Nanocomplexes for Improved Transport of Salmon Calcitonin across the Intestine

scientific article published on 10 February 2020

Folding artificial mucosa with cell-laden hydrogels guided by mechanics models

article published in the Proceedings of the National Academy of Sciences of the United States of America

Formation of Highly Porous Polymeric Foams with Controlled Release Capability: A Phase-Separation Technique

scientific article published on 01 January 1999

Formulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expression.

scientific article

Functional nanofiber scaffolds with different spacers modulate adhesion and expansion of cryopreserved umbilical cord blood hematopoietic stem/progenitor cells.

scientific article published on May 2007

Galactosylated PVDF membrane promotes hepatocyte attachment and functional maintenance

scientific article published in December 2003

Galactosylated poly(vinylidene difluoride) hollow fiber bioreactor for hepatocyte culture

scientific article published on November 2005

Galactosylated ternary DNA/polyphosphoramidate nanoparticles mediate high gene transfection efficiency in hepatocytes.

scientific article published on February 2005

Gelatin/chondroitin 6-sulfate microspheres for the delivery of therapeutic proteins to the joint

scientific article published on December 1998

Gene transfer by DNA-gelatin nanospheres.

scientific article published on January 1999

Gene transfer to hemophilia A mice via oral delivery of FVIII-chitosan nanoparticles

scientific article published on 27 June 2008

Glaucoma Filtration Surgery in Monkeys Using 5-Fluorouridine in Polyanhydride Disks

scientific article published in March 1990

Growth inhibition of the 9L glioma using polymers to release heparin and cortisone acetate

scientific article published in October 1990

Guidance of stem cell fate on 2D patterned surfaces

scientific article published on 28 June 2012

HPV Oncogene Manipulation Using Nonvirally Delivered CRISPR/Cas9 or Natronobacterium gregoryi Argonaute

scientific article published on 18 May 2018

Harnessing localized ridges for high-aspect-ratio hierarchical patterns with dynamic tunability and multifunctionality

scientific article published on 12 December 2013

Hepatic differentiation potential of commercially available human mesenchymal stem cells

scientific article published in December 2006

Hepatocyte Encapsulation for Enhanced Cellular Functions

scientific article published in October 2000

High density of immobilized galactose ligand enhances hepatocyte attachment and function ⬇️

scientific article published on December 15, 2003

High-throughput screening of microchip-synthesized genes in programmable double-emulsion droplets

scientific article

High-throughput screening of microscale pitted substrate topographies for enhanced nonviral transfection efficiency in primary human fibroblasts.

scientific article

Highly Aligned Nanofibrous Scaffold Derived from Decellularized Human Fibroblasts

scientific article

Hydrogen-Bonded Tannic Acid-Based Anticancer Nanoparticle for Enhancement of Oral Chemotherapy

scientific article published on 16 November 2018

Hyperbranched poly(amino ester)s with different terminal amine groups for DNA delivery

scientific article

Immobilization of galactose ligands on acrylic acid graft-copolymerized poly(ethylene terephthalate) film and its application to hepatocyte culture

scientific article published in January 2003

Implantation of mouse embryonic stem cell-derived cardiac progenitor cells preserves function of infarcted murine hearts

scientific article

Improvements in Solubility and Stability of Thalidomide upon Complexation with Hydroxypropyl-β-Cyclodextrin

scientific article published in July 1992

In vitro and in vivo studies of subcutaneous hydromorphone implants designed for the treatment of cancer pain

scientific article published in May 1996

In vitro chondrogenesis of mesenchymal stem cells in recombinant silk-elastinlike hydrogels.

scientific article published on 3 April 2007

In vitro gene delivery using polyamidoamine dendrimers with a trimesyl core.

scientific article

In vitro release of vascular endothelial growth factor from gadolinium-doped biodegradable microspheres.

scientific article published on June 2004

In vivo US monitoring of catheter-based vascular delivery of gene microspheres in pigs: feasibility.

scientific article published in August 2003

In vivo evaluation of plasmid DNA encoding OP-1 protein for spine fusion

scientific article published on September 2006

In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF).

scientific article published on 7 November 2007

Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues

scientific article

Inducing enhanced immunogenic cell death with nanocarrier-based drug delivery systems for pancreatic cancer therapy

scientific article published on 18 June 2016

Inducing hepatic differentiation of human mesenchymal stem cells in pellet culture

scientific article published on 17 April 2006

Injectable drug-delivery systems based on supramolecular hydrogels formed by poly(ethylene oxide)s and alpha-cyclodextrin.

scientific article published in May 2003

Integration of drug, protein, and gene delivery systems with regenerative medicine

scientific article

Interaction of human mesenchymal stem cells with disc cells: changes in extracellular matrix biosynthesis

scientific article published in August 2006

Interactions of phospholipid bilayer with chitosan: effect of molecular weight and pH.

scientific article published in January 2001

Intranasal gene transfer by chitosan-DNA nanospheres protects BALB/c mice against acute respiratory syncytial virus infection

scientific article

Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity

scientific article

Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells.

scientific article

Low oxygen tension and synthetic nanogratings improve the uniformity and stemness of human mesenchymal stem cell layer

scientific article published on 23 February 2010

MR imaging of biodegradable polymeric microparticles: a potential method of monitoring local drug delivery

scientific article published in March 2005

Magnetoactive sponges for dynamic control of microfluidic flow patterns in microphysiological systems.

scientific article

Mast cell-derived particles deliver peripheral signals to remote lymph nodes

scientific article published on 05 October 2009

Materials innovation for co-delivery of diverse therapeutic cargos

scientific article published on December 2013

Mechanical behavior of human embryonic stem cell pellet under unconfined compression

scientific article published on 21 August 2011

Messenger RNA (mRNA) nanoparticle tumour vaccination

scientific article

Micellization phenomena of biodegradable amphiphilic triblock copolymers consisting of poly(beta-hydroxyalkanoic acid) and poly(ethylene oxide).

scientific article published in September 2005

MicroRNA delivery for regenerative medicine

scientific article published on 27 May 2015

Microcapsules with improved mechanical stability for hepatocyte culture

scientific article published in May 2003

Microfluidic Isolation and Enrichment of Nanoparticles

scientific article published on 30 November 2020

Microfluidic preparation of polymer-nucleic acid nanocomplexes improves nonviral gene transfer

scientific article published on 6 November 2013

Microfluidic synthesis of multifunctional Janus particles for biomedical applications.

scientific article published on 14 May 2012

Microfluidics-mediated isothermal detection of enzyme activity at the single molecule level

scientific article published on January 2011

Microscale oral delivery devices incorporating nanoparticles.

scientific article published on February 2010

Microwave tumour coagulation plus in situ treatment with cytokine-microparticles: induction of potent anti-residual tumour immunity

scientific article published on May 2005

Mitigation of hypertrophic scar contraction via an elastomeric biodegradable scaffold

scientific article published on 7 January 2015

Modeling SARS-CoV-2 infection in individuals with opioid use disorder with brain organoids

scientific article published in 2021

Morphology, Migration, and Transcriptome Analysis of Schwann Cell Culture on Butterfly Wings with Different Surface Architectures

article

Multi-layered microcapsules for cell encapsulation

scientific article published in February 2002

Multifunctional nanorods for gene delivery

scientific article published on 14 September 2003

Multifunctional nanorods serving as nanobridges to modulate T cell-mediated immunity

scientific article published on 09 October 2013

Musculoskeletal differentiation of cells derived from human embryonic germ cells

scientific article

Myogenic Induction of Aligned Mesenchymal Stem Cell Sheets by Culture on Thermally Responsive Electrospun Nanofibers

scientific article published on January 2007

N-acetylglucosamine and adenosine derivatized surfaces for cell culture: 3T3 fibroblast and chicken hepatocyte response

scientific article published on April 1994

NanoCluster Beacons as reporter probes in rolling circle enhanced enzyme activity detection

scientific article

Nanografted Substrata and Triculture of Human Pericytes, Fibroblasts, and Endothelial Cells for Studying the Effects on Angiogenesis

scientific article published on 28 March 2016

Nanograting structure promotes lamellipodia-based cell collective migration and wound healing

scientific article

Nanoparticle- and biomaterials-mediated oral delivery for drug, gene, and immunotherapy.

scientific article published on 19 February 2013

Nanoparticle-mediated inhibition of survivin to overcome drug resistance in cancer therapy

scientific article published on 15 April 2016

Nanopattern-induced changes in morphology and motility of smooth muscle cells.

scientific article published on September 2005

Nanoscale surfacing for regenerative medicine

scientific article published on September 2010

Nanotopography alters nuclear protein expression, proliferation and differentiation of human mesenchymal stem/stromal cells

scientific article published on 18 December 2014

Nanotopography as modulator of human mesenchymal stem cell function.

scientific article published on 18 April 2012

Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells

scientific article

Natural polymers for gene delivery and tissue engineering

scientific article published on 9 June 2006

New polyphosphoramidate with a spermidine side chain as a gene carrier.

scientific article published on September 2002

Nonendocytic delivery of lipoplex nanoparticles into living cells using nanochannel electroporation

scientific article published on 29 August 2013

Nonviral direct conversion of primary mouse embryonic fibroblasts to neuronal cells.

scientific article

Nonviral gene delivery from nonwoven fibrous scaffolds fabricated by interfacial complexation of polyelectrolytes

scientific article published on 23 February 2006

Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide.

scientific article published on 23 April 2018

Novel anisotropic engineered cardiac tissues: studies of electrical propagation.

scientific article published on 2 August 2007

Nucleic acid scavengers inhibit thrombosis without increasing bleeding.

scientific article

Nucleic acid scavenging microfiber mesh inhibits trauma-induced inflammation and thrombosis

scientific article

Nucleic acid-based nanoengineering: novel structures for biomedical applications

scientific article published on 28 June 2011

Nucleic acid-binding polymers as anti-inflammatory agents

scientific article

Nucleic acid-binding polymers as anti-inflammatory agents: reducing the danger of nuclear attack

scientific article published in January 2012

Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium

scientific article published on 18 July 2008

Oral Nonviral Gene Delivery for Chronic Protein Replacement Therapy

scientific article published in August 2018

Oral gene delivery with chitosan--DNA nanoparticles generates immunologic protection in a murine model of peanut allergy.

scientific article published in April 1999

Peripheral nerve regeneration by microbraided poly(L-lactide-co-glycolide) biodegradable polymer fibers.

scientific article published in February 2004

Phase II Randomized Trial of Autologous Formalin-Fixed Tumor Vaccine for Postsurgical Recurrence of Hepatocellular Carcinoma

scientific article published in March 2004

Photo-crosslinkable microcapsules formed by polyelectrolyte copolymer and modified collagen for rat hepatocyte encapsulation

scientific article published in August 2004

Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP+CD4+ T cells

scientific article

Pluripotent stem cell-derived cardiac tissue patch with advanced structure and function

scientific article

Poly(D,L-lactide-co-ethyl ethylene phosphate)s as new drug carriers

scientific article

Poly(L-lactic acid) foams with cell seeding and controlled-release capacity

scientific article published in April 1996

Poly(alpha-hydroxy acids): carriers for bone morphogenetic proteins

scientific article published on January 1996

Poly(ethylene glycol) Hydrogel Scaffolds Containing Cell-Adhesive and Protease-Sensitive Peptides Support Microvessel Formation by Endothelial Progenitor Cells

scientific article published on 20 October 2015

Poly(ethylene imine)-g-chitosan using EX-810 as a spacer for nonviral gene delivery vectors.

scientific article

Poly(phosphoester) ionomers as tissue-engineering scaffolds.

scientific article published in July 2004

Polyanhydrides for controlled release of bioactive agents

scientific article published on September 1986

Polycationic Nanofibers for Nucleic Acid Scavenging.

scientific article

Polyelectrolyte complex films derived from polyethyleneoxide-maleic acid copolymer and chitosan: preparation and characterization

scientific article published in May 2004

Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA.

scientific article published on July 2005

Polyphosphoester microspheres for sustained release of biologically active nerve growth factor

scientific article

Polyphosphoesters in drug and gene delivery ⬇️

scientific article published on April 25, 2003

Polyphosphoramidate gene carriers: effect of charge group on gene transfer efficiency.

scientific article published on June 2004

Preparation and characterization of polypseudorotaxanes based on block-selected inclusion complexation between poly(propylene oxide)-poly(ethylene oxide)-poly(propylene oxide) triblock copolymers and alpha-cyclodextrin

scientific article

Proliferation and differentiation of human embryonic germ cell derivatives in bioactive polymeric fibrous scaffold.

scientific article published on January 2005

Proliferation and differentiation of human mesenchymal stem cell encapsulated in polyelectrolyte complexation fibrous scaffold

scientific article published on 21 August 2006

Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum dot-FRET.

scientific article published on 8 January 2008

Quantum dot-based theranostics

scientific article published on 06 October 2009

Quantum-dots-FRET nanosensors for detecting unamplified nucleic acids by single molecule detection

scientific article published in June 2006

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

scientific article

Radiation-inducible caspase-8 gene therapy for malignant brain tumors

scientific article published on 11 April 2008

Radio-responsive gene therapy for malignant glioma cells without the radiosensitive promoter: Caspase-3 gene therapy combined with radiation

scientific article published on 27 April 2006

Radioresponsive tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene therapy for malignant brain tumors

scientific article published on June 2007

Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment

scientific article

Rat hepatocyte morphology and function on lactose-derivatized polystyrene surfaces

scientific article published in February 1996

Recent advances in nanoparticle-mediated siRNA delivery

scientific article

Repeated intrathecal administration of plasmid DNA complexed with polyethylene glycol-grafted polyethylenimine led to prolonged transgene expression in the spinal cord

scientific article published in July 2003

Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels

scientific article

Scalable Manufacturing of Enteric Encapsulation Systems for Site-Specific Oral Insulin Delivery

scientific article published on 11 December 2018

Scalable production of core-shell nanoparticles by flash nanocomplexation to enhance mucosal transport for oral delivery of insulin.

scientific article published on 31 January 2018

Self-assembled supramolecular hydrogels formed by biodegradable PEO-PHB-PEO triblock copolymers and alpha-cyclodextrin for controlled drug delivery

scientific article

Shape-controlled synthesis of hybrid nanomaterials via three-dimensional hydrodynamic focusing

scientific article

Signal-on Protein Detection via Dye Translocation between Aptamer and Quantum Dot.

scientific article published on 21 April 2016

Significance of synthetic nanostructures in dictating cellular response.

scientific article published on March 2005

Simultaneous Non-invasive Analysis of DNA Condensation and Stability by Two-step QD-FRET

scientific article published on April 2009

Simultaneous delivery of siRNA and paclitaxel via a "two-in-one" micelleplex promotes synergistic tumor suppression

scientific article published on 4 January 2011

Small intestinal submucosa as a potential bioscaffold for intervertebral disc regeneration.

scientific article published in October 2006

Smart multifunctional drug delivery towards anticancer therapy harmonized in mesoporous nanoparticles

scientific article published on 11 August 2015

Spatial profiling of chromatin accessibility in mouse and human tissues

scientific article published in September 2022

Stable immobilization of rat hepatocyte spheroids on galactosylated nanofiber scaffold.

scientific article published in May 2005

Stem cell differentiation indicated by noninvasive photonic characterization and fractal analysis of subcellular architecture

scientific article published on 22 June 2011

Surface-aminated electrospun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cells.

scientific article published on 18 July 2006

Surface-immobilization of adhesion peptides on substrate for ex vivo expansion of cryopreserved umbilical cord blood CD34+ cells

scientific article published on 10 January 2006

Sustained release of papaverine for the treatment of cerebral vasospasm: in vitro evaluation of release kinetics and biological activity

scientific article published in November 1992

Sustained release of proteins from electrospun biodegradable fibers.

scientific article published in July 2005

Sustained viral gene delivery through core-shell fibers

scientific article published on 17 June 2009

Synthesis and characterization of putrescine-based poly(phosphoester-urethanes)

scientific article published on 01 January 1993

Synthesis of fluorosurfactants for emulsion-based biological applications.

scientific article

Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes

scientific article published on 22 January 2012

Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage.

scientific article published on 12 March 2007

Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells

scientific article published on 9 August 2016

Targeted tumor cell death induced by autologous tumor-specific T lymphocyte recognition of wild-type p53-derived peptides

scientific article published on January 2006

Temperature-Controlled Encapsulation and Release of an Active Enzyme in the Cavity of a Self-Assembled DNA Nanocage

scientific article published on 01 November 2013

Temperature-responsive hydroxybutyl chitosan for the culture of mesenchymal stem cells and intervertebral disk cells

scientific article published on 22 August 2005

Ternary complexes comprising polyphosphoramidate gene carriers with different types of charge groups improve transfection efficiency.

scientific article

The convergence of quantum-dot-mediated fluorescence resonance energy transfer and microfluidics for monitoring DNA polyplex self-assembly in real time

scientific article

The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons

scientific article

The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation.

scientific article

The effect of the degree of chitosan deacetylation on the efficiency of gene transfection

scientific article published on October 2004

The inhibition of anti-DNA binding to DNA by nucleic acid binding polymers.

scientific article

The role of electrospinning in the emerging field of nanomedicine.

scientific article published on January 2006

The use of magnetic resonance imaging to track controlled drug release and transport in the brain.

scientific article published in January 1993

Thermally responsive polymeric micellar nanoparticles self-assembled from cholesteryl end-capped random poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide): synthesis, temperature-sensitivity, and morphologies.

scientific article

Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance.

scientific article published on 13 June 2005

Three-dimensional culture of rabbit nucleus pulposus cells in collagen microspheres.

scientific article published on 16 August 2011

Three-dimensional hydrodynamic focusing method for polyplex synthesis.

scientific article

Tissue compatibility of interfacial polyelectrolyte complexation fibrous scaffold: evaluation of blood compatibility and biocompatibility.

scientific article published on February 2007

Tissue-engineered bone formation with gene transfer and mesenchymal stem cells in a minimally invasive technique

scientific article published on July 2007

Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming

scientific article

Transdifferentiation of human endothelial progenitors into smooth muscle cells

scientific article published on 03 February 2016

Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format.

scientific article published on 7 January 2013

Transgene expression in the brain stem effected by intramuscular injection of polyethylenimine/DNA complexes

scientific article

Transient Depletion of Kupffer Cells Leads to Enhanced Transgene Expression in Rat Liver Following Retrograde Intrabiliary Infusion of Plasmid DNA and DNA Nanoparticles ⬇️

scientific article published on March 4, 2011

Transport of chitosan-DNA nanoparticles in human intestinal M-cell model versus normal intestinal enterocytes

scientific article

Treatment of severe sepsis with nanoparticulate cell-free DNA scavengers

scientific article published on 29 May 2020

Tuning physical properties of nanocomplexes through microfluidics-assisted confinement

scientific article

Understanding nonviral nucleic acid delivery with quantum dot-FRET nanosensors

scientific article published on April 2012

Uptake and intracellular fate of multifunctional nanoparticles: a comparison between lipoplexes and polyplexes via quantum dot mediated Förster resonance energy transfer

scientific article

Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening.

scientific article

Use of ultrathin shell microcapsules of hepatocytes in bioartificial liver-assist device.

scientific article published in January 2003

Vector modifications to eliminate transposase expression following piggyBac-mediated transgenesis

scientific article published on 10 December 2014

Viscoelastic behaviour of human mesenchymal stem cells.

scientific article published on 22 July 2008

Water-soluble and nonionic polyphosphoester: synthesis, degradation, biocompatibility and enhancement of gene expression in mouse muscle

scientific article published in March 2004

Whole blood cells loaded with messenger RNA as an anti-tumor vaccine.

scientific article

pH responsive adhesion of phospholipid vesicle on poly(acrylic acid) cushion grafted to poly(ethylene terephthalate) surface

scientific article published in May 2005

Paulina is supported by:

About Paulina

Help