List of works - Josep Vendrell i Roca

A functional and structural study of the major metalloprotease secreted by the pathogenic fungus Aspergillus fumigatus

scientific article

A new type of five-membered heterocyclic inhibitors of basic metallocarboxypeptidases.

scientific article published on 5 April 2009

AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides

scientific article

Amyloid fibril formation by a partially structured intermediate state of alpha-chymotrypsin.

scientific article

Analysis of a new crystal form of procarboxypeptidase B: further insights into the catalytic mechanism

scientific article

Aromatic organic compounds as scaffolds for metallocarboxypeptidase inhibitor design.

scientific article published in January 2009

Carboxypeptidase B

Caught after the Act: a human A-type metallocarboxypeptidase in a product complex with a cleaved hexapeptide

scientific article

Crystal structure of a novel mid-gut procarboxypeptidase from the cotton pest Helicoverpa armigera

scientific article

Cyclobutane-containing peptides: evaluation as novel metallocarboxypeptidase inhibitors and modelling of their mode of action

scientific article published on 23 April 2009

Design, selection, and characterization of thioflavin-based intercalation compounds with metal chelating properties for application in Alzheimer's disease

scientific article published in February 2009

Detailed molecular comparison between the inhibition mode of A/B-type carboxypeptidases in the zymogen state and by the endogenous inhibitor latexin

scientific article

Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid)

scientific article

Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library.

scientific article published on 22 September 2017

Human kallikrein 6 activity is regulated via an autoproteolytic mechanism of activation/inactivation.

scientific article published in June 2004

Human procarboxypeptidase B: three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI)

scientific article

Identification and characterization of three members of the human metallocarboxypeptidase gene family

scientific article

Ile-phe dipeptide self-assembly: clues to amyloid formation

scientific article published on 15 December 2006

Insect Gut Carboxypeptidase 3

scholarly article published 2013

Linking amyloid protein aggregation and yeast survival

scientific article

Major kinetic traps for the oxidative folding of leech carboxypeptidase inhibitor

scientific article

Mutagenesis of the central hydrophobic cluster in Abeta42 Alzheimer's peptide. Side-chain properties correlate with aggregation propensities

scientific article published on February 2006

NMR solution structure of the activation domain of human procarboxypeptidase A2

scientific article

Prediction of "hot spots" of aggregation in disease-linked polypeptides

scientific article

Procarboxypeptidase A from the insect pest Helicoverpa armigera and its derived enzyme. Two forms with new functional properties.

scientific article

Progress in metallocarboxypeptidases and their small molecular weight inhibitors

scientific article published on 11 May 2010

Response of the digestive system of Helicoverpa zea to ingestion of potato carboxypeptidase inhibitor and characterization of an uninhibited carboxypeptidase B.

scientific article published on 26 May 2006

Secondary binding site of the potato carboxypeptidase inhibitor. Contribution to its structure, folding, and biological properties

scientific article published in June 2004

Self-assembly of human latexin into amyloid-like oligomers.

scientific article

Structural and Functional Analysis of the Complex between Citrate and the Zinc Peptidase Carboxypeptidase A

scientific article

Structural and functional characterization of binding sites in metallocarboxypeptidases based on Optimal Docking Area analysis

scientific article published in July 2007

Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors

scientific article

Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin

scientific article

The X-Ray Structure of Carboxypeptidase A Inhibited by a Thiirane Mechanism-Based Inhibitor

scientific article

The crystal structure of thrombin-activable fibrinolysis inhibitor (TAFI) provides the structural basis for its intrinsic activity and the short half-life of TAFIa

scientific article published on 31 July 2008

The unfolding pathway of leech carboxypeptidase inhibitor

scientific article published on 13 March 2002

Thioxophosphoranyl aryl- and heteroaryloxiranes as the representants of a new class of metallocarboxypeptidase inhibitors

scientific article published on 23 March 2008

List of works by Josep Vendrell i Roca

A functional and structural study of the major metalloprotease secreted by the pathogenic fungus Aspergillus fumigatus

A new type of five-membered heterocyclic inhibitors of basic metallocarboxypeptidases.

AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides

Amyloid fibril formation by a partially structured intermediate state of alpha-chymotrypsin.

Analysis of a new crystal form of procarboxypeptidase B: further insights into the catalytic mechanism

Aromatic organic compounds as scaffolds for metallocarboxypeptidase inhibitor design.

Carboxypeptidase B

Caught after the Act: a human A-type metallocarboxypeptidase in a product complex with a cleaved hexapeptide

Crystal structure of a novel mid-gut procarboxypeptidase from the cotton pest Helicoverpa armigera

Cyclobutane-containing peptides: evaluation as novel metallocarboxypeptidase inhibitors and modelling of their mode of action

Design, selection, and characterization of thioflavin-based intercalation compounds with metal chelating properties for application in Alzheimer's disease

Detailed molecular comparison between the inhibition mode of A/B-type carboxypeptidases in the zymogen state and by the endogenous inhibitor latexin

Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid)

Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library.

Human kallikrein 6 activity is regulated via an autoproteolytic mechanism of activation/inactivation.

Human procarboxypeptidase B: three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI)

Identification and characterization of three members of the human metallocarboxypeptidase gene family

Ile-phe dipeptide self-assembly: clues to amyloid formation

Insect Gut Carboxypeptidase 3

Linking amyloid protein aggregation and yeast survival

Major kinetic traps for the oxidative folding of leech carboxypeptidase inhibitor

Mutagenesis of the central hydrophobic cluster in Abeta42 Alzheimer's peptide. Side-chain properties correlate with aggregation propensities

NMR solution structure of the activation domain of human procarboxypeptidase A2

Prediction of "hot spots" of aggregation in disease-linked polypeptides

Procarboxypeptidase A from the insect pest Helicoverpa armigera and its derived enzyme. Two forms with new functional properties.

Progress in metallocarboxypeptidases and their small molecular weight inhibitors

Response of the digestive system of Helicoverpa zea to ingestion of potato carboxypeptidase inhibitor and characterization of an uninhibited carboxypeptidase B.

Secondary binding site of the potato carboxypeptidase inhibitor. Contribution to its structure, folding, and biological properties

Self-assembly of human latexin into amyloid-like oligomers.

Structural and Functional Analysis of the Complex between Citrate and the Zinc Peptidase Carboxypeptidase A

Structural and functional characterization of binding sites in metallocarboxypeptidases based on Optimal Docking Area analysis

Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors

Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin

The X-Ray Structure of Carboxypeptidase A Inhibited by a Thiirane Mechanism-Based Inhibitor

The crystal structure of thrombin-activable fibrinolysis inhibitor (TAFI) provides the structural basis for its intrinsic activity and the short half-life of TAFIa

The unfolding pathway of leech carboxypeptidase inhibitor

Thioxophosphoranyl aryl- and heteroaryloxiranes as the representants of a new class of metallocarboxypeptidase inhibitors