List of works - José M Fernández-Fernández

A Ca(v)3.2/syntaxin-1A signaling complex controls T-type channel activity and low-threshold exocytosis

scientific article

A Single Amino Acid Deletion (ΔF1502) in the S6 Segment of CaV2.1 Domain III Associated with Congenital Ataxia Increases Channel Activity and Promotes Ca2+ Influx

scientific journal article

A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia

scientific article published on 04 August 2009

A mutation in the first intracellular loop of CACNA1A prevents P/Q channel modulation by SNARE proteins and lowers exocytosis.

scientific article

Activation and inhibition of neuronal G protein-gated inwardly rectifying K(+) channels by P2Y nucleotide receptors

scientific article

BK channel activation by tungstate requires the β1 subunit extracellular loop residues essential to modulate voltage sensor function and channel gating.

scientific article published on 26 October 2013

Bradykinin, but not muscarinic, inhibition of M-current in rat sympathetic ganglion neurons involves phospholipase C-beta 4

scientific journal article

Cannabis Users Show Enhanced Expression of CB1-5HT2A Receptor Heteromers in Olfactory Neuroepithelium Cells

scientific article published on 2 January 2018

Constitutive activation of G-proteins by polycystin-1 is antagonized by polycystin-2

scientific article published on 10 January 2002

Contribution of syntaxin 1A to the genetic susceptibility to migraine: a case-control association study in the Spanish population

scientific article published on 6 March 2009

Cross talk between β subunits, intracellular Ca2+ signaling, and SNAREs in the modulation of CaV 2.1 channel steady-state inactivation.

scientific article

DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors

scientific article

Early-onset severe spinocerebellar ataxia 42 with neurodevelopmental deficits (SCA42ND): Case report, pharmacological trial, and literature review

scientific article published on 24 October 2020

Functional coupling of GABAA/B receptors and the channel TRPV4 mediates rapid progesterone signaling in the oviduct

scientific article published on 14 August 2018

Gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertension

scientific article

Genetic variation in the KCNMA1 potassium channel α subunit as risk factor for severe essential hypertension and myocardial infarction

scientific article published on 01 November 2008

Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking

scientific article

KCNE4 suppresses Kv1.3 currents by modulating trafficking, surface expression and channel gating

scientific article published on 22 September 2009

Late-onset episodic ataxia type 2 associated with a novel loss-of-function mutation in the CACNA1A gene.

scientific article

Missense mutations of CACNA1A are a frequent cause of autosomal dominant nonprogressive congenital ataxia

scientific article published on 30 November 2016

Multiple pertussis toxin-sensitive G-proteins can couple receptors to GIRK channels in rat sympathetic neurons when expressed heterologously, but only native G(i)-proteins do so in situ

scientific article

Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses.

scientific article published on 5 February 2018

Plasma membrane voltage-dependent anion channel mediates antiestrogen-activated maxi Cl- currents in C1300 neuroblastoma cells.

scientific article

Protective effect of the KCNMB1 E65K genetic polymorphism against diastolic hypertension in aging women and its relevance to cardiovascular risk.

scientific article

RING1B contributes to Ewing sarcoma development by repressing the NaV1.6 sodium channel and the NF-κB pathway, independently of the fusion oncoprotein

scientific article published on 15 June 2016

Rare CACNA1A mutations leading to congenital ataxia

scientific article published on 26 May 2020

SNP variants within the vanilloid TRPV1 and TRPV3 receptor genes are associated with migraine in the Spanish population.

scientific article published on 7 December 2011

Screening of CACNA1A and ATP1A2 genes in hemiplegic migraine: clinical, genetic, and functional studies.

scientific article published on 02 July 2013

Selective activation of heterologously expressed G protein-gated K+ channels by M2 muscarinic receptors in rat sympathetic neurones

scientific article

Stroke-Like Episodes and Cerebellar Syndrome in Phosphomannomutase Deficiency (PMM2-CDG): Evidence for Hypoglycosylation-Driven Channelopathy.

scientific article published on 22 February 2018

Structural determinants of 5',6'-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel.

scientific article

Swelling-activated Ca2+ entry via TRPV4 channel is defective in cystic fibrosis airway epithelia.

scientific article

TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells.

scientific article published on 28 May 2013

TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity

scientific article

The hemiplegic migraine-associated Y1245C mutation in CACNA1A results in a gain of channel function due to its effect on the voltage sensor and G-protein-mediated inhibition

scientific article

Tricyclic antidepressants block cholinergic nicotinic receptors and ATP secretion in bovine chromaffin cells

scientific article published on 01 November 1997

Tungstate activates BK channels in a β subunit- and Mg2+-dependent manner: relevance for arterial vasodilatation

Tungstate-targeting of BKαβ1 channels tunes ERK phosphorylation and cell proliferation in human vascular smooth muscle.

scientific article published on 6 February 2015

Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed.

scientific article published on 28 January 2016

omega-Agatoxin IVA blocks nicotinic receptor channels in bovine chromaffin cells

scientific article published on 01 March 1995

omega-Conotoxin GVIA blocks nicotine-induced catecholamine secretion by blocking the nicotinic receptor-activated inward currents in bovine chromaffin cells

scientific article published on 01 May 1995

List of works by José M Fernández-Fernández

A Ca(v)3.2/syntaxin-1A signaling complex controls T-type channel activity and low-threshold exocytosis

A Single Amino Acid Deletion (ΔF1502) in the S6 Segment of CaV2.1 Domain III Associated with Congenital Ataxia Increases Channel Activity and Promotes Ca2+ Influx

A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia

A mutation in the first intracellular loop of CACNA1A prevents P/Q channel modulation by SNARE proteins and lowers exocytosis.

Activation and inhibition of neuronal G protein-gated inwardly rectifying K(+) channels by P2Y nucleotide receptors

BK channel activation by tungstate requires the β1 subunit extracellular loop residues essential to modulate voltage sensor function and channel gating.

Bradykinin, but not muscarinic, inhibition of M-current in rat sympathetic ganglion neurons involves phospholipase C-beta 4

Cannabis Users Show Enhanced Expression of CB1-5HT2A Receptor Heteromers in Olfactory Neuroepithelium Cells

Constitutive activation of G-proteins by polycystin-1 is antagonized by polycystin-2

Contribution of syntaxin 1A to the genetic susceptibility to migraine: a case-control association study in the Spanish population

Cross talk between β subunits, intracellular Ca2+ signaling, and SNAREs in the modulation of CaV 2.1 channel steady-state inactivation.

DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors

Early-onset severe spinocerebellar ataxia 42 with neurodevelopmental deficits (SCA42ND): Case report, pharmacological trial, and literature review

Functional coupling of GABAA/B receptors and the channel TRPV4 mediates rapid progesterone signaling in the oviduct

Gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertension

Genetic variation in the KCNMA1 potassium channel α subunit as risk factor for severe essential hypertension and myocardial infarction

Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking

KCNE4 suppresses Kv1.3 currents by modulating trafficking, surface expression and channel gating

Late-onset episodic ataxia type 2 associated with a novel loss-of-function mutation in the CACNA1A gene.

Missense mutations of CACNA1A are a frequent cause of autosomal dominant nonprogressive congenital ataxia

Multiple pertussis toxin-sensitive G-proteins can couple receptors to GIRK channels in rat sympathetic neurons when expressed heterologously, but only native G(i)-proteins do so in situ

Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses.

Plasma membrane voltage-dependent anion channel mediates antiestrogen-activated maxi Cl- currents in C1300 neuroblastoma cells.

Protective effect of the KCNMB1 E65K genetic polymorphism against diastolic hypertension in aging women and its relevance to cardiovascular risk.

RING1B contributes to Ewing sarcoma development by repressing the NaV1.6 sodium channel and the NF-κB pathway, independently of the fusion oncoprotein

Rare CACNA1A mutations leading to congenital ataxia

SNP variants within the vanilloid TRPV1 and TRPV3 receptor genes are associated with migraine in the Spanish population.

Screening of CACNA1A and ATP1A2 genes in hemiplegic migraine: clinical, genetic, and functional studies.

Selective activation of heterologously expressed G protein-gated K+ channels by M2 muscarinic receptors in rat sympathetic neurones

Stroke-Like Episodes and Cerebellar Syndrome in Phosphomannomutase Deficiency (PMM2-CDG): Evidence for Hypoglycosylation-Driven Channelopathy.

Structural determinants of 5',6'-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel.

Swelling-activated Ca2+ entry via TRPV4 channel is defective in cystic fibrosis airway epithelia.

TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells.

TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity

The hemiplegic migraine-associated Y1245C mutation in CACNA1A results in a gain of channel function due to its effect on the voltage sensor and G-protein-mediated inhibition

Tricyclic antidepressants block cholinergic nicotinic receptors and ATP secretion in bovine chromaffin cells

Tungstate activates BK channels in a β subunit- and Mg2+-dependent manner: relevance for arterial vasodilatation

Tungstate-targeting of BKαβ1 channels tunes ERK phosphorylation and cell proliferation in human vascular smooth muscle.

Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed.

omega-Agatoxin IVA blocks nicotinic receptor channels in bovine chromaffin cells

omega-Conotoxin GVIA blocks nicotine-induced catecholamine secretion by blocking the nicotinic receptor-activated inward currents in bovine chromaffin cells