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List of works by Mark Rubin

"Lineage addiction" in human cancer: lessons from integrated genomics

scientific article published on January 2005

A Comparative Study of ERG Status Assessment on DNA, mRNA, and Protein Levels Using Unique Samples from a Swedish Biopsy Cohort

article

A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors

scientific article published on 31 May 2016

A Germline DNA Polymorphism Enhances Alternative Splicing of theKLF6Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk

article

A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers

scientific article published on 19 September 2018

A Preliminary Study of JM-27: A Serum Marker That Can Specifically Identify Men With Symptomatic Benign Prostatic Hyperplasia

article

A Working Group Classification of Focal Prostate Atrophy Lesions

article

A comprehensive approach toward novel serum biomarkers for benign prostatic hyperplasia: the MPSA Consortium

scientific article

A functional thrombin receptor (PAR1) is expressed on bone-derived prostate cancer cell lines.

scientific article published on November 2002

A germline FANCA alteration that is associated with increased sensitivity to DNA damaging agents

scientific article published on 3 May 2017

A hierarchical Naïve Bayes Model for handling sample heterogeneity in classification problems: an application to tissue microarrays.

scientific article

A phase II trial of gefitinib in patients with non-metastatic hormone-refractory prostate cancer

scientific article published in October 2007

A variant TMPRSS2 isoform and ERG fusion product in prostate cancer with implications for molecular diagnosis

scientific article published in August 2008

ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease

scientific article

APC/CTNNB1 (?-catenin) pathway alterations in human prostate cancers

article

Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance

scientific article published on 3 November 2017

Aberrant cytoplasmic expression of p63 and prostate cancer mortality

scientific article published on 20 January 2009

Abnormal prostate development in C3(1)-bcl-2 transgenic mice

article

Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction

scientific article published on February 2006

Active surveillance for prostate cancer: the role of the pathologist

article

Aggressive variants of castration-resistant prostate cancer

scientific article

AlleleSeq: analysis of allele-specific expression and binding in a network framework

scientific article published on 2 August 2011

Alpha-Methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions

scientific article

Alterations in homologous recombination repair genes in prostate cancer brain metastases

scientific article published on 03 May 2022

Amplification and overexpression of prosaposin in prostate cancer

scientific article published in December 2005

An emerging role for cytopathology in precision oncology.

scientific article published on 7 December 2015

An illustration of the potential for mapping MRI/MRS parameters with genetic over-expression profiles in human prostate cancer

scientific article published on 28 August 2008

An oncogenic role for ETV1 in melanoma

scientific article

An oncogenic role for the multiple endocrine neoplasia type 1 gene in prostate cancer.

scientific article

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

scientific article published on 05 February 2020

Anatomical retro-apical technique of synchronous (posterior and anterior) urethral transection: a novel approach for ameliorating apical margin positivity during robotic radical prostatectomy

scientific article published in November 2010

Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

scientific article published on July 2009

Androgen-Independent Prostate Cancer Is a Heterogeneous Group of Diseases

article

Antibody-based detection of ERG rearrangement-positive prostate cancer

scientific article

Antibody-independent targeted quantification of TMPRSS2-ERG fusion protein products in prostate cancer.

scientific article

Apoptosis and expression of Bcl-2, Bcl-XL, and Bax in renal cell carcinomas.

scientific article

Application of oligonucleotide microarrays to assess the biological effects of neoadjuvant imatinib mesylate treatment for localized prostate cancer

scientific article published in January 2006

Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma

scientific article (publication date: 11 December 2007)

Assessment of a fragment of e-cadherin as a serum biomarker with predictive value for prostate cancer.

scientific article published on June 2005

Association of oncofetal protein expression with clinical outcomes in patients with urothelial carcinoma of the bladder

scientific article

Autoantibody signatures in prostate cancer

scientific article published in September 2005

Automated immunofluorescence analysis defines microvessel area as a prognostic parameter in clear cell renal cell cancer

article

BPH gene expression profile associated to prostate gland volume

scientific article published on December 2008

Basal cell cocktail (34betaE12 + p63) improves the detection of prostate basal cells

scientific article published on March 2003

Benign positive margins after radical prostatectomy means a poor prognosis--con

scientific article published in February 2005

Benign prostatic glands at surgical margins of radical prostatectomy specimens: frequency and associated risk factors

scientific article published on 01 November 2000

Beyond PSA: the next generation of prostate cancer biomarkers

scientific article published on March 2012

Biobanking after robotic-assisted radical prostatectomy: a quality assessment of providing prostate tissue for RNA studies

scientific article

Bioinformatics approach leads to the discovery of the TMPRSS2:ETS gene fusion in prostate cancer

scientific article published on 18 September 2006

Biologic classification as an alternative to anatomic staging for clinically localized prostate cancer: a proposal based on patients treated with external beam radiotherapy

scientific article published on 01 February 1998

Biology and evolution of poorly differentiated neuroendocrine tumors

scientific article published in June 2017

Bladder neck-sparing modification of radical prostatectomy adversely affects surgical margins in pathologic T3a prostate cancer

article

Bone biopsy protocol for advanced prostate cancer in the era of precision medicine.

scientific article published on 19 December 2017

Bringing Pathobiology into Focus

CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis

scientific article published on 01 May 2019

CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis

scientific article published on 28 March 2019

COMPLETE TRANSURETHRAL RESECTION OF BLADDER ENDOCERVICOSIS

scientific article published on 01 February 2001

Can perineural invasion on prostate needle biopsy predict prostate specific antigen recurrence after radical prostatectomy?

scientific article published on July 1999

Challenges in Recognizing Treatment-Related Neuroendocrine Prostate Cancer

scientific article published on 19 November 2012

Changes in biochemical disease-free survival rates as a result of adoption of the consensus conference definition in patients with clinically localized prostate cancer treated with external-beam radiotherapy

scientific article published in June 1998

Characterization of KRAS rearrangements in metastatic prostate cancer

scientific article published on June 2011

Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications

scientific article published on June 2008

Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer

scientific article

Characterization of ZAG protein expression in prostate cancer using a semi-automated microscope system

scientific article published in July 2006

Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target

scientific article published on 20 March 2019

Characterization of the leiomyomatous variant of myofibroblastoma: a rare subset distinct from other smooth muscle tumors of the breast.

scientific article published on 3 August 2016

Characterizing the cancer genome in lung adenocarcinoma

scientific article

Chromatin to Clinic: The Molecular Rationale for PARP1 Inhibitor Function

scientific article published on June 2015

Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study

scientific article published on 09 July 2018

Clinical significance of TTF-1 protein expression and TTF-1 gene amplification in lung adenocarcinoma

scientific article

Clonal evaluation of prostate cancer foci in biopsies with discontinuous tumor involvement by dual ERG/SPINK1 immunohistochemistry

scientific article published on 8 January 2016

Clonal evolution of chemotherapy-resistant urothelial carcinoma.

scientific article published on 17 October 2016

Collagen XXIII expression is associated with prostate cancer recurrence and distant metastases

scientific article

Combining urinary detection of TMPRSS2:ERG and PCA3 with serum PSA to predict diagnosis of prostate cancer

scientific article published on 19 May 2011

Common gene rearrangements in prostate cancer

scientific article published on 22 August 2011

Common germline-somatic variant interactions in advanced urothelial cancer

scientific article published on 03 December 2020

Common structural and epigenetic changes in the genome of castration-resistant prostate cancer

scientific article published on 7 December 2011

Comparison of external radiation therapy vs radical prostatectomy in lymph node positive prostate cancer patients.

scientific article

Comparison of the basal cell-specific markers, 34betaE12 and p63, in the diagnosis of prostate cancer

scientific article

Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer

article

Concurrent AURKA and MYCN gene amplifications are harbingers of lethal treatment-related neuroendocrine prostate cancer

scientific article published on January 2013

Consensus statement with recommendations on active surveillance inclusion criteria and definition of progression in men with localized prostate cancer: the critical role of the pathologist

scientific article

Contemporary grading for prostate cancer: implications for patient care

scientific article published on 17 October 2012

Cribriform carcinoma of the prostate and cribriform prostatic intraepithelial neoplasia: incidence and clinical implications

scientific article published on July 1998

Current Thoughts on the Role of the Androgen Receptor and Prostate Cancer Progression

scientific article published on 01 September 2005

Cyclin D1 expression in human prostate carcinoma cell lines and primary tumors

scientific article published on May 1998

Cytogenetic alterations in renal tumors. Applications for comparative genomic hybridization and fluorescence in situ hybridization

scientific article

DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns

scientific article published on 01 February 2019

DNA Repair in Prostate Cancer: Biology and Clinical Implications

scientific article

DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA alkylation repair and cancer cell proliferation

scientific article

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer ⬇️

scientific article

Decreased alpha-methylacyl CoA racemase expression in localized prostate cancer is associated with an increased rate of biochemical recurrence and cancer-specific death

scientific article

Defining aggressive prostate cancer using a 12-gene model

scientific article

Detection of TMPRSS2-ERG fusion gene expression in prostate cancer specimens by a novel assay using branched DNA.

scientific article published on 3 August 2009

Detection of circulating prostate carcinoma cells via an enhanced reverse transcriptase-polymerase chain reaction assay in patients with early stage prostate carcinoma. Independence from other pretreatment characteristics

scientific article published on 01 June 1997

Detection of early prostate cancer using a hepsin-targeted imaging agent

scientific article

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

scientific article published on 20 October 2013

Development and validation of a whole-exome sequencing test for simultaneous detection of point mutations, indels and copy-number alterations for precision cancer care

scientific article published on 20 July 2016

Development of an integrated prostate cancer research information system.

scientific article

Diagnosis of NUT midline carcinoma using a NUT-specific monoclonal antibody

scientific article

Diagnosis of melanoma aspirates on ThinPrep®: The University of Michigan experience

scientific article published on 01 May 2002

Diagnostic Usefulness of Monoclonal Antibody P504S in the Workup of Atypical Prostatic Glandular Proliferations ⬇️

scientific article published on November 1, 2003

Diagnostic utility of MYC amplification and anti-MYC immunohistochemistry in atypical vascular lesions, primary or radiation-induced mammary angiosarcomas, and primary angiosarcomas of other sites.

scientific article

Die TMPRSS2-ETS-Genfusion beim Prostatakarzinom

Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing

scientific article

Distinct ERG rearrangement prevalence in prostate cancer: higher frequency in young age and in low PSA prostate cancer.

scientific article published on 5 February 2013

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

scientific article published on August 2007

Distinct genomic aberrations associated with ERG rearranged prostate cancer

scientific article published on April 2009

Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer

scientific article published on 8 February 2016

Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer

scientific article published on 02 February 2021

Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression

scientific article published on 02 December 2021

E-cadherin expression in prostate cancer: a broad survey using high-density tissue microarray technology.

scientific article

EML4-ALK fusion lung cancer: a rare acquired event

scientific article

ERG cooperates with androgen receptor in regulating trefoil factor 3 in prostate cancer disease progression

scientific article

ERG induces taxane resistance in castration-resistant prostate cancer

scientific article

ERG rearrangement is present in a subset of transition zone prostatic tumors

scientific article published on 06 August 2010

ERG rearrangement is specific to prostate cancer and does not occur in any other common tumor

scientific article published on 14 May 2010

ERG rearrangement metastasis patterns in locally advanced prostate cancer

scientific article published on April 2010

ETS gene fusions in prostate cancer: from discovery to daily clinical practice

scientific article published on 24 April 2009

ETS rearrangements in prostate cancer

scientific article published on 16 April 2012

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells ⬇️

scientific article published on September 19, 2003

Effect of finasteride on risk of prostate cancer: how little we really know.

scientific article published on February 2004

Effects of long-term finasteride treatment on prostate cancer morphology and clinical outcome

scientific article

Elevated E2F1 inhibits transcription of the androgen receptor in metastatic hormone-resistant prostate cancer

scientific article published in December 2006

Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression

scientific article published on 11 December 2012

Epigenomic alterations in localized and advanced prostate cancer

scientific article published on April 2013

Erratum: Corrigendum: High-throughput oncogene mutation profiling in human cancer

article

Erstellung eines molekularen Markerprofils zur Prognose des Verlaufs bei der benignen Prostatahyperplasie

scientific article published on 01 September 2007

Establishment of a living biobank : Improved guidance of precision cancer care with in vitro and in vivo cancer models

scientific article published on 27 September 2017

Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer

scientific article

Evaluating localized prostate cancer and identifying candidates for focal therapy

scientific article published in December 2008

Evaluation of the interobserver reproducibility of Gleason grading of prostatic adenocarcinoma using tissue microarrays

scientific article published in May 2003

Evidence for molecular differences in prostate cancer between African American and Caucasian men

scientific article

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

scientific article

Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo

scientific article published in June 2003

Expression of the platelet-derived growth factor receptor in prostate cancer and treatment implications with tyrosine kinase inhibitors

scientific article

Expression profiling of human renal carcinomas with functional taxonomic analysis.

scientific article

Focal therapy for localized prostate cancer: a critical appraisal of rationale and modalities

scientific article published on 15 October 2007

Frequency and clinicopathologic correlates of KRAS amplification in non-small cell lung carcinoma

scientific article published on 08 April 2011

Frequent truncating mutations of STAG2 in bladder cancer

scientific article published on 13 October 2013

From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer

scientific article published on July 2012

Functional characterization of BC039389-GATM and KLK4-KRSP1 chimeric read-through transcripts which are up-regulated in renal cell cancer

scientific article published on 27 March 2015

FusionSeq: a modular framework for finding gene fusions by analyzing Paired-End RNA-Sequencing data

scientific article (publication date: 2010)

G3BP1 inhibits Cul3<sup>SPOP</sup> to amplify AR signaling and promote prostate cancer

scientific article published on 18 November 2021

Gene-expression profiles in hereditary breast cancer.

scientific article

Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer

scientific article

Genome-Wide Linkage Analysis of TMPRSS2-ERG Fusion in Familial Prostate Cancer

article

Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation

scientific article published on 28 August 2012

Genomic Correlates to the Newly Proposed Grading Prognostic Groups for Prostate Cancer

scientific article published on 9 November 2015

Genomic rearrangements in prostate cancer

scientific article

Gleason score and lethal prostate cancer: does 3 + 4 = 4 + 3?

scientific article published on 11 May 2009

Golgi protein GOLM1 is a tissue and urine biomarker of prostate cancer

scientific article

Haploinsufficiency and reduced expression of genes localized to the 8p chromosomal region in human prostate tumors

article

Health: Make precision medicine work for cancer care

scientific article

Heterogeneous nuclear ribonucleoprotein K is a novel regulator of androgen receptor translation

scientific article

High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development

scientific article published on 19 December 2013

High-density tissue microarray

scientific article published in September 2002

High-throughput oncogene mutation profiling in human cancer

article

Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis

scientific article published on July 2005

How Well Does the Gleason Score Predict Prostate Cancer Death? A 20-Year Followup of a Population Based Cohort in Sweden

scientific article published in April 2006

Human bladder cancer diagnosis using Multiphoton microscopy

scientific article

Human prostate sphere-forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo

scientific article

Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma

scientific article

Identification of functionally active, low frequency copy number variants at 15q21.3 and 12q21.31 associated with prostate cancer risk

scientific article published on 10 April 2012

Identification of molecular tumor markers in renal cell carcinomas with TFE3 protein expression by RNA sequencing

scientific article

Identification of novel prostate cancer drivers using RegNetDriver: a framework for integration of genetic and epigenetic alterations with tissue-specific regulatory network

scientific article

Identification of the transcription factor single-minded homologue 2 as a potential biomarker and immunotherapy target in prostate cancer

scientific article

Identification of two molecular groups of seminomas by using expression and tissue microarrays

scientific article

Identifying an ERG-positive Subclass with Clinical Progression Using Expression Profiling

scientific article published on 26 March 2013

Image-based computational quantification and visualization of genetic alterations and tumour heterogeneity

scientific article published on 7 April 2016

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

scientific article published on 01 November 2018

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

scientific article published on 04 September 2018

Immunohistochemical and clinicopathological correlation of the metastasis-associated gene 1 (MTA1) expression in benign and malignant pancreatic endocrine tumors

scientific article published on 17 April 2009

Impact of constitutional copy number variants on biological pathway evolution

scientific article

Impact of the SPOP Mutant Subtype on the Interpretation of Clinical Parameters in Prostate Cancer

scientific article published on 24 July 2018

Inadequate formalin fixation decreases reliability of p27Kip1 immunohistochemical staining: Probing optimal fixation time using high-density tissue microarrays

scientific article published on 01 July 2002

Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer

scientific article published in March 2006

Inferring loss-of-heterozygosity from unpaired tumors using high-density oligonucleotide SNP arrays

scientific article

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

scientific article published on 06 July 2016

Inherited determinants of early recurrent somatic mutations in prostate cancer.

scientific article

Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET-rearranged thyroid cancer

scientific article published on 05 May 2022

Insights into the mechanism of organ-specific cancer metastasis

scientific article published on November 2014

Integrative Clinical Genomics of Advanced Prostate Cancer

scientific article

Integrative analysis of genomic aberrations associated with prostate cancer progression

scientific article

Integrative annotation of variants from 1092 humans: application to cancer genomics

scientific article

Integrative clinical genomics of advanced prostate cancer

scientific article

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

scientific article (publication date: 7 July 2005)

Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression

article

Integrative microarray analysis of pathways dysregulated in metastatic prostate cancer

scientific article published in November 2007

Integrative molecular concept modeling of prostate cancer progression.

scientific article

Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes

scientific article published on 24 April 2020

Internet-based Profiler system as integrative framework to support translational research

scientific article

Interobserver reproducibility of Gleason grading: evaluation using prostate cancer tissue microarrays

scientific article published on 8 April 2008

Intertubular growth in pure seminomas: associations with poor prognostic parameters

scientific article published on 01 June 2005

Intravascular Large Cell Lymphoma Coexisting Within Hemangiomas of the Skin

scientific article published on 01 July 1997

JAGGED1 expression is associated with prostate cancer metastasis and recurrence

scientific article

KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis.

scientific article

Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease

scientific article

Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses

scientific article published in Nature Communications

Loss of SLC45A3 protein (prostein) expression in prostate cancer is associated with SLC45A3-ERG gene rearrangement and an unfavorable clinical course.

scientific article published on 30 August 2012

Loss of SPINK1 expression is associated with unfavorable outcomes in urothelial carcinoma of the bladder after radical cystectomy

scientific article published in September 2012

Loss of an Androgen-Inactivating and Isoform-Specific HSD17B4 Splice Form Enables Emergence of Castration-Resistant Prostate Cancer.

scientific article published in January 2018

MAGI3–AKT3 fusion in breast cancer amended

scientific article published in Nature

MUC-1 gene is associated with prostate cancer death: a 20-year follow-up of a population-based study in Sweden

scientific article published on 28 August 2007

MYB-NFIB gene fusion in adenoid cystic carcinoma of the breast with special focus paid to the solid variant with basaloid features

article

Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015.

scientific article published on 3 June 2015

Mediastinal seminoma in a patient with Wiskott-Aldrich syndrome

scientific article

Molecular Characterization of Prostate Cancer Following Androgen Deprivation: The Devil in the Details

scientific article published on 30 August 2013

Molecular and cytogenetic characterization of plexiform leiomyomata provide further evidence for genetic heterogeneity underlying uterine fibroids

scientific article published on 10 April 2008

Molecular archeology: unearthing androgen-induced structural rearrangements in prostate cancer genomes

scientific article

Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model.

scientific article

Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets

scientific article

Molecular genetics of human prostate cancer.

scientific article

Molecular genetics of prostate cancer: emerging appreciation of genetic complexity ⬇️

scientific article published on January 1, 2012

Molecular profiling and the identification of genes associated with metastatic oral cavity/pharynx squamous cell carcinoma

scientific article published in March 2004

Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty.

scientific article published on 17 November 2004

Molecular prostate cancer pathology: current issues and achievements.

scientific article

Molecular sampling of prostate cancer: a dilemma for predicting disease progression

scientific article

Morphological features of TMPRSS2-ERG gene fusion prostate cancer

scientific article published in May 2007

Multicenter Evaluation of the Prostate Health Index to Detect Aggressive Prostate Cancer in Biopsy Naïve Men.

scientific article

Multiphoton microscopy for structure identification in human prostate and periprostatic tissue: implications in prostate cancer surgery

scientific article

Multiphoton microscopy in the evaluation of human bladder biopsies

scientific article published on May 2012

N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer

scientific journal article

N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer

scientific article

NSD2 is a conserved driver of metastatic prostate cancer progression

scientific article published in Nature Communications

New strategies in prostate cancer: translating genomics into the clinic

scientific article

Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor target

scientific article

Next-generation prostate cancer biobanking: toward a processing protocol amenable for the International Cancer Genome Consortium

scientific article

Nine-gene molecular signature is not associated with prostate cancer death in a watchful waiting cohort

scientific article published in January 2008

Non-coding genetic variation in cancer

scientific article published on 01 February 2017

Novel MIR143-NOTCH fusions in benign and malignant glomus tumors

scientific article published on 2 September 2013

Novel YAP1-TFE3 fusion defines a distinct subset of epithelioid hemangioendothelioma

scientific article

Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma

scientific article published on 25 January 2013

On-site Cytology for Development of Patient-Derived Three-dimensional Organoid Cultures - A Pilot Study

scientific article published in April 2017

Oncogene-mediated alterations in chromatin conformation

scientific article

Oncogenic transcription factors as master regulators of chromatin topology: a new role for ERG in prostate cancer

scientific article

Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease

scientific article

Organoid cultures derived from patients with advanced prostate cancer

scientific article

Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer

scientific article published in June 2004

PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer

scientific article

Partially circumventing peripheral tolerance for oncogene-specific prostate cancer immunotherapy

scientific article

Pathway and network analysis of more than 2500 whole cancer genomes

scientific article published on 05 February 2020

Pathway biomarker profiling of localized and metastatic human prostate cancer reveal metastatic and prognostic signatures

scientific article

Patient derived organoids to model rare prostate cancer phenotypes.

scientific article

Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney

scientific article published on June 2009

Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

scientific article

Platelet-Derived Growth Factor Receptor Inhibitor Imatinib Mesylate and Docetaxel: A Modular Phase I Trial in Androgen-Independent Prostate Cancer

scientific article published on 01 February 2005

Postprostatectomy cancer-free survival of African Americans is similar to non-African Americans after adjustment for baseline cancer severity

scientific article published in January 2004

Predictors of short postoperative prostate-specific antigen doubling time for patients diagnosed during PSA era

scientific article published on 01 March 2005

Predisposition for TMPRSS2-ERG Fusion in Prostate Cancer by Variants in DNA Repair Genes

article

Preoperative parameters for predicting early prostate cancer recurrence after radical prostatectomy

scientific article published on 01 May 2002

Prevalence and Location of Peripheral Nerve Found on Prostate Needle Biopsy

scientific article published on 01 January 2001

Prevalence of TMPRSS2-ERG and SLC45A3-ERG gene fusions in a large prostatectomy cohort

scientific article

Prevalence of TMPRSS2-ERG fusion prostate cancer among men undergoing prostate biopsy in the United States

scientific article published on 7 July 2009

Profiling critical cancer gene mutations in clinical tumor samples

scientific article

Prognostic factors in lymph node-positive prostate cancer

scientific article published on 01 May 2006

Proposed morphologic classification of prostate cancer with neuroendocrine differentiation

scientific article published on June 2014

Prospective evaluation of AMACR (P504S) and basal cell markers in the assessment of routine prostate needle biopsy specimens

scientific article published on December 2004

Prostate Power Play: Does Pik3ca Accelerate Pten-Deficient Cancer Progression?

scientific article published on 01 June 2018

Prostate cancer involving the bladder neck: recurrence-free survival and implications for AJCC staging modification

scientific article published on 01 August 2002

Prostate cancer with Paneth cell-like neuroendocrine differentiation has recognizable histomorphology and harbors AURKA gene amplification

scientific article published on 26 June 2014

Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4.

scientific article published on 14 August 2017

Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover

scientific article published on 4 April 2013

Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer

scientific article

Prostate needle biopsy reporting: how are the surgical members of the Society of Urologic Oncology using pathology reports to guide treatment of prostate cancer patients?

scientific article

Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee.

scientific article published on March 2004

Prostate-specific membrane antigen expression as a predictor of prostate cancer progression

scientific article

Publisher Correction: Suppression of insulin feedback enhances the efficacy of PI3K inhibitors

scientific article published in Nature

Publisher Correction: The long tail of oncogenic drivers in prostate cancer

scientific article published on 01 July 2019

Punctuated evolution of prostate cancer genomes

scientific article published on April 2013

Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics

scientific article published on 15 August 2017

RHAMM (CD168) is overexpressed at the protein level and may constitute an immunogenic antigen in advanced prostate cancer disease

scientific article

Racial Variation in the Utility of Urinary Biomarkers PCA3 and T2ERG in a Large Multicenter Study.

scientific article published on 20 January 2017

Rapid autopsy of a patient with recurrent anaplastic ependymoma

scientific article

Re: Stoehr et al. Lack of evidence for frequent MED12 p.L1224F mutation in prostate tumours from Caucasian patients. J Pathol 2013; 230: 453-456.

scientific article published in October 2013

Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

scientific article

Recurrent NCOA2 gene rearrangements in congenital/infantile spindle cell rhabdomyosarcoma

scientific article published on 05 March 2013

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

scientific article

Recurrent prostate cancer genomic alterations predict response to brachytherapy treatment

scientific article

Relationship and significance of greatest percentage of tumor and perineural invasion on needle biopsy in prostatic adenocarcinoma

scientific article published on February 2000

Relevance of cohort design for studying the frequency of the ERG rearrangement in prostate cancer

scholarly article by Martin Braun et al published June 2011 in Histopathology

Renal Oncocytosis

article

Report From the International Society of Urological Pathology (ISUP) Consultation Conference on Molecular Pathology of Urogenital Cancers. I. Molecular Biomarkers in Prostate Cancer

scientific article published on 10 February 2020

Response to ‘TMPRSS2-ERG gene fusions are infrequent in prostatic ductal adenocarcinomas’

article

Retinoid metabolism and ALDH1A2 (RALDH2) expression are altered in the transgenic adenocarcinoma mouse prostate model

scientific article published on 21 June 2009

Role of non-coding sequence variants in cancer

scientific article

Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity

scientific article published on 03 November 2020

Role of the TMPRSS2-ERG gene fusion in prostate cancer

scientific article

Role of transcriptional corepressor CtBP1 in prostate cancer progression

scientific article

SLC45A3-ELK4 is a novel and frequent erythroblast transformation-specific fusion transcript in prostate cancer

scientific article

SNP panel identification assay (SPIA): a genetic-based assay for the identification of cell lines

scientific article published on 27 February 2008

SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer

article

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas ⬇️

scientific article

SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling.

scientific article published in March 2017

SPOP mutation drives prostate neoplasia without stabilizing oncogenic transcription factor ERG.

scientific article published on 4 December 2017

SPOP mutation leads to genomic instability in prostate cancer.

scientific article

SPOP mutations in prostate cancer across demographically diverse patient cohorts.

scientific article published on January 2014

SPOP-Mutated/CHD1-Deleted Lethal Prostate Cancer and Abiraterone Sensitivity

scientific article published on 01 August 2018

Saturation biopsy protocol enhances prediction of pT3 and surgical margin status on prostatectomy specimen

scientific article published on 07 November 2006

Scaffold attachment factor B1 regulates the androgen receptor in concert with the growth inhibitory kinase MST1 and the methyltransferase EZH2

scientific article published on 29 July 2013

Selective detection of histologically aggressive prostate cancer: an Early Detection Research Network Prediction model to reduce unnecessary prostate biopsies with validation in the Prostate Cancer Prevention Trial

scientific article

Serum Autoantibodies in Chronic Prostate Inflammation in Prostate Cancer Patients

scientific article published on 10 February 2016

Should a Gleason score be assigned to a minute focus of carcinoma on prostate biopsy?

scientific article published on December 2000

Signal-to-noise ratio in squeezed-light laser radar ⬇️

scientific article

Single focus prostate cancer: pathological features and ERG fusion status.

scientific article published on 17 December 2010

Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) beyond SMARCA4 Mutations: A Comprehensive Genomic Analysis

scientific article published on 19 June 2020

Somatic copy number alterations by whole-exome sequencing implicates YWHAZ and PTK2 in castration-resistant prostate cancer.

scientific article

Suppression of insulin feedback enhances the efficacy of PI3K inhibitors

scientific article published in Nature

TET2 deficiency causes germinal center hyperplasia, impairs plasma cell differentiation and promotes B-cell lymphomagenesis

scientific article published on 01 October 2018

TMPRSS2-ERG Fusion Prostate Cancer: An Early Molecular Event Associated With Invasion

scientific article published on 01 June 2007

TMPRSS2-ERG fusion heterogeneity in multifocal prostate cancer: clinical and biologic implications

scientific article published on October 2007

TMPRSS2-ERG gene fusion prevalence and class are significantly different in prostate cancer of Caucasian, African-American and Japanese patients

scientific article

TMPRSS2-ETS fusion prostate cancer: biological and clinical implications

scientific article published on November 2007

TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer

scientific article published on September 2006

TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort.

scientific article published on 22 January 2007

TMPRSS2:ERG gene fusion predicts subsequent detection of prostate cancer in patients with high-grade prostatic intraepithelial neoplasia

scientific article published on 02 December 2013

TTF1 expression in non-small cell lung carcinoma: association with TTF1 gene amplification and improved survival

scientific article published in January 2009

Targeted genomic sequencing of pediatric Burkitt lymphoma identifies recurrent alterations in antiapoptotic and chromatin-remodeling genes

scientific article published on 22 October 2012

Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity

scientific article published on 05 September 2012

Targeted therapy of cancer: new roles for pathologists--prostate cancer

scientific article published on May 2008

Tech.Sight. Understanding disease cell by cell.

scientific article

Testing a multigene signature of prostate cancer death in the Swedish Watchful Waiting Cohort

scientific article published on 26 June 2008

Testing mutual exclusivity of ETS rearranged prostate cancer

scientific article

The Genomics of Prostate Cancer: emerging understanding with technologic advances

scientific article published in January 2018

The Lethal Clone in Prostate Cancer: Redefining the Index

scientific article published on 02 January 2014

The Molecular Evolution of Castration-resistant Prostate Cancer

scientific article published on 09 December 2016

The Placental Gene PEG10 Promotes Progression of Neuroendocrine Prostate Cancer

scientific article published on 29 July 2015

The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance

scientific article published on 30 July 2019

The critical role of the pathologist in determining eligibility for active surveillance as a management option in patients with prostate cancer: consensus statement with recommendations supported by the College of American Pathologists, Internationa

scientific article published on 05 August 2014

The detection of renal carcinoma cells in the peripheral blood with an enhanced reverse transcriptase-polymerase chain reaction assay for MN/CA9

scientific article published on 01 August 1999

The diagnostic utility of novel immunohistochemical marker ERG in the workup of prostate biopsies with "atypical glands suspicious for cancer".

scientific article published on April 2011

The genomic complexity of primary human prostate cancer

scientific article

The landscape of somatic copy-number alteration across human cancers

scientific article

The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer

scientific article published on 21 December 2021

The long tail of oncogenic drivers in prostate cancer.

scientific article published on 2 April 2018

The mutational landscape of prostate cancer

scientific article

The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer

scientific article

The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus

scientific article

The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1

scientific article

The role of SPINK1 in ETS rearrangement-negative prostate cancers

scientific article

The role of calpain in the proteolytic cleavage of E-cadherin in prostate and mammary epithelial cells

scientific article published on 19 October 2002

The role of metastasis-associated protein 1 in prostate cancer progression

scientific article published in February 2004

The role of the reverse-transcriptase polymerase chain reaction assay for prostate-specific antigen in the selection of patients for radical prostatectomy

scientific article

Tissue microarray sampling strategy for prostate cancer biomarker analysis

scientific article published on March 2002

Tissue-preserving approach to extracting DNA from paraffin-embedded specimens using tissue microarray technology

scientific article

Tissue-print and print-phoresis as platform technologies for the molecular analysis of human surgical specimens: mapping tumor invasion of the prostate capsule

scientific article

Toward a prostate cancer precision medicine

scientific article published on 20 November 2014

Transcriptomic heterogeneity in multifocal prostate cancer

scientific article

Transforming growth factor β-receptor II protein expression in benign prostatic hyperplasia is associated with prostate volume and inflammation

scientific article published on 14 September 2010

Translational crossroads for biomarkers

scientific article

Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer

scientific article

Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy

scientific article published on 14 April 2009

Truncation of the beta-catenin binding domain of E-cadherin precedes epithelial apoptosis during prostate and mammary involution

scientific article

Turkey must end violent response to protests

scientific article

Unraveling the clonal hierarchy of somatic genomic aberrations.

scientific article

Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling

scientific article published on 05 July 2019

Urine TMPRSS2:ERG fusion transcript stratifies prostate cancer risk in men with elevated serum PSA.

scientific article published on August 2011

Use of fine needle aspiration for solid breast lesions is accurate and cost-effective.

scientific article published in December 1997

Usefulness of basal cell cocktail (34betaE12 + p63) in the diagnosis of atypical prostate glandular proliferations

scientific article

Using molecular markers to predict outcome.

scientific article

V-ets erythroblastosis virus E26 oncogene homolog (avian)/Trefoil factor 3/high-molecular-weight cytokeratin triple immunostain: a novel tissue-based biomarker in prostate cancer with potential clinical application

scientific article published on 12 July 2013

Validation in a multiple urology practice cohort of the Prostate Cancer Prevention Trial calculator for predicting prostate cancer detection

scientific article

Validation of a TFE3 break-apart FISH assay for Xp11.2 translocation renal cell carcinomas

scientific article published in September 2011

Variants at IRX4 as prostate cancer expression quantitative trait loci

scientific article published on 11 September 2013

Visual cues as a surrogate for tactile feedback during robotic-assisted laparoscopic prostatectomy: posterolateral margin rates in 1340 consecutive patients

scientific article

Web-based tissue microarray image data analysis: initial validation testing through prostate cancer Gleason grading.

scientific article

What Information are Urologists Extracting from Prostate Needle Biopsy Reports and What do They Need for Clinical Management of Prostate Cancer?

scientific article published on 09 August 2005

Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors

scientific article

Whole transcriptome amplification for gene expression profiling and development of molecular archives

scientific article published in February 2006

mRNA expression signature of Gleason grade predicts lethal prostate cancer

scientific article published on 2 May 2011

α-Methylacyl-CoA racemase expression and lethal prostate cancer in the Physicians' Health Study and Health Professionals Follow-up Study

scientific article published on 28 June 2011

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