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List of works by Andrew D Krystal

A WASO sub-group analysis of a 6-month study of eszopiclone 3 mg.

scientific article published on 31 March 2012

A comparison of rates of residual insomnia symptoms following pharmacotherapy or cognitive-behavioral therapy for major depressive disorder.

scientific article published in February 2007

A compendium of placebo-controlled trials of the risks/benefits of pharmacological treatments for insomnia: the empirical basis for U.S. clinical practice

scientific article published on 18 January 2009

A double-blind, placebo-controlled study of armodafinil for excessive sleepiness in patients with treated obstructive sleep apnea and comorbid depression

scientific article published on 29 December 2009

A polysomnography study of eszopiclone in elderly patients with insomnia

scientific article published in September 2006

A randomized proof-of-mechanism trial applying the 'fast-fail' approach to evaluating κ-opioid antagonism as a treatment for anhedonia

scientific article published on 30 March 2020

An evaluation of the efficacy and safety of eszopiclone over 12 months in patients with chronic primary insomnia

scientific article

Antidepressant and Antipsychotic Drugs ⬇️

scientific article published on December 1, 2010

Assessing depression symptoms in those with insomnia: an examination of the beck depression inventory second edition (BDI-II).

scientific article published on 26 October 2008

Associations of a regulatory polymorphism of monoamine oxidase-A gene promoter (MAOA-uVNTR) with symptoms of depression and sleep quality

scientific article published on June 2007

Behavioral insomnia therapy for fibromyalgia patients: a randomized clinical trial

scientific article published in November 2005

Case report: Successful riluzole augmentation therapy in treatment-resistant bipolar depression following the development of rash with lamotrigine

scientific article

Comparison of diary-derived bladder and sleep measurements across OAB individuals, primary insomniacs, and healthy controls

scientific article published on 2 August 2012

Comparison of polysomnographic data in age-, sex- and Axis I psychiatric diagnosis matched HIV-seropositive and HIV-seronegative insomnia patients

scientific article

Comparison of seizure duration, ictal EEG, and cognitive effects of ketamine and methohexital anesthesia with ECT.

scientific article

Daily left prefrontal repetitive transcranial magnetic stimulation in the acute treatment of major depression: clinical predictors of outcome in a multisite, randomized controlled clinical trial

scientific article published on 13 August 2008

Depression and insomnia in women

scientific article published in January 2004

Detrusor overactivity persisting at night and preceding nocturia in patients with overactive bladder syndrome: a nocturnal cystometrogram and polysomnogram study

scientific article

Does physiological hyperarousal enhance error rates among insomnia sufferers?

scientific article published on August 2013

Durability of clinical benefit with transcranial magnetic stimulation (TMS) in the treatment of pharmacoresistant major depression: assessment of relapse during a 6-month, multisite, open-label study

scientific article

Effects of antipsychotic medications on sleep in schizophrenia

scientific article published on May 2008

Efficacy and Safety of Doxepin 1 mg and 3 mg in a 12-week Sleep Laboratory and Outpatient Trial of Elderly Subjects with Chronic Primary Insomnia.

scientific article

Efficacy and safety of doxepin 3 and 6 mg in a 35-day sleep laboratory trial in adults with chronic primary insomnia

scientific article

Eszopiclone co-administered with fluoxetine in patients with insomnia coexisting with major depressive disorder

scientific article published on 3 April 2006

Eszopiclone coadministered with escitalopram in patients with insomnia and comorbid generalized anxiety disorder

scientific article published on May 2008

Eszopiclone treatment for insomnia: effect size comparisons in patients with primary insomnia and insomnia with medical and psychiatric comorbidity

scientific article

Evaluation of eszopiclone discontinuation after cotherapy with fluoxetine for insomnia with coexisting depression

scientific article published in February 2007

Feasibility and Acceptability of Wearable Sleep Electroencephalogram Device Use in Adolescents: Observational Study

scientific article published on 01 October 2020

How the circadian rhythm affects sleep, wakefulness, and overall health: background for understanding shift work disorder

scientific article published in February 2012

Hypnotics should be considered for the initial treatment of chronic insomnia. Pro.

scientific article published in April 2005

In vivo evidence of the specificity of effects of GABA(A) receptor modulating medications.

scientific article published on July 2010

Individualized Low-Amplitude Seizure Therapy: Minimizing Current for Electroconvulsive Therapy and Magnetic Seizure Therapy

scientific article published on 28 April 2015

Insomnia in women

scientific article published on January 2003

Insomnia is frequent in schizophrenia and associated with night eating and obesity

scientific article

Introduction: Definitions, measurements, and management in insomnia.

scientific article published in January 2004

Is cellular energy monitoring more responsive to hypoxia than pulse oximetry?

scientific article published on 26 May 2020

It is time to take a stand for medical research and against terrorism targeting medical scientists

scientific article

Left dorsolateral prefrontal transcranial magnetic stimulation (TMS): sleep factor changes during treatment in patients with pharmacoresistant major depressive disorder

scientific article published on 25 September 2012

Long-term efficacy and safety of zolpidem extended-release 12.5 mg, administered 3 to 7 nights per week for 24 weeks, in patients with chronic primary insomnia: a 6-month, randomized, double-blind, placebo-controlled, parallel-group, multicenter stu

scientific article

Long-term issues in the treatment of sleep disorders

scientific article published in July 2007

Loop diuretics have anxiolytic effects in rat models of conditioned anxiety

scientific article

Low-Frequency Ictal EEG Activity and ECT Therapeutic Impact

scientific article published on 01 January 1993

Measuring sleep quality

scientific article published on September 2008

Modeling slow-wave activity dynamics: does an exponentially dampened periodic function really fit a single night of normal human sleep?

scientific article published on 4 November 2008

Multifactorial determinants of the neurocognitive effects of electroconvulsive therapy

scientific article

NREM sleep EEG frequency spectral correlates of sleep complaints in primary insomnia subtypes.

scientific article published in September 2002

Novel sublingual low-dose zolpidem tablet reduces latency to sleep onset following spontaneous middle-of-the-night awakening in insomnia in a randomized, double-blind, placebo-controlled, outpatient study

scientific article published on February 2013

Obstructive sleep apnea and delirium: exploring possible mechanisms

scientific article published on 14 April 2013

Obstructive sleep apnea and incidence of postoperative delirium after elective knee replacement in the nondemented elderly

scientific article published in April 2012

Optimizing the Pharmacologic Treatment of Insomnia: Current Status and Future Horizons

scientific article published on September 2013

Panel discussion: changing how we think about insomnia

scientific article published in January 2004

Pharmacological advances in the treatment of insomnia

scientific article published on January 2011

Psychiatric disorders and sleep

scientific article

Psychotic disorder in a patient with central and extrapontine myelinolysis

Repetitive transcranial magnetic stimulation of the superior frontal gyrus modulates craving for cigarettes

scientific article published on 18 July 2011

Report of two cases where sleep related eating behavior occurred with the extended-release formulation but not the immediate-release formulation of a sedative-hypnotic agent.

scientific article published on April 2008

Review of the histamine system and the clinical effects of H1 antagonists: basis for a new model for understanding the effects of insomnia medications

scientific article published on 26 January 2013

Selective kappa-opioid antagonism ameliorates anhedonic behavior: evidence from the Fast-fail Trial in Mood and Anxiety Spectrum Disorders (FAST-MAS)

scientific article published on 16 June 2020

Shift work disorder case studies: applying management principles in clinical practice

scientific article published in August 2012

Should we be anxious when assessing anxiety using the Beck Anxiety Inventory in clinical insomnia patients?

scientific article

Sleep and psychiatric disorders: future directions

scientific article published on December 2006

Sleep and residual sedation after administration of zaleplon, zolpidem, and placebo during experimental middle-of-the-night awakening.

scientific article

Sleep disturbance in psychiatric disorders: effects on function and quality of life in mood disorders, alcoholism, and schizophrenia

scientific article published on January 2008

Sleep quality varies as a function of 5-HTTLPR genotype and stress

scientific article published on 31 August 2007

Sleep-wake functioning along the cancer continuum: focus group results from the Patient-Reported Outcomes Measurement Information System (PROMIS(®))

scientific article

Subtyping primary insomnia: is sleep state misperception a distinct clinical entity?

scientific article

Sustained efficacy of eszopiclone over 6 months of nightly treatment: results of a randomized, double-blind, placebo-controlled study in adults with chronic insomnia

scientific article

Testing the reliability and validity of DSM-IV-TR and ICSD-2 insomnia diagnoses. Results of a multitrait-multimethod analysis

scientific article

The association of fatigue with depression and insomnia in HIV-seropositive patients: a pilot study

scientific article published on December 2011

The changing perspective on chronic insomnia management.

scientific article published on January 2004

The consensus sleep diary: standardizing prospective sleep self-monitoring

scientific article published on February 2012

The effect of insomnia definitions, terminology, and classifications on clinical practice

scientific article

The effect of vestibular stimulation in a four-hour sleep phase advance model of transient insomnia ⬇️

scientific article published on August 15, 2010

The pharmacologic management of insomnia in patients with HIV.

scientific article published on June 2009

The possibility of preventing functional impairment due to sleep loss by pharmacologically enhancing sleep.

scientific article published in January 2005

The relationship of sleep with temperature and metabolic rate in a hibernating primate

scientific article published in 2013

The treatment of primary insomnia.

scientific article published in December 2009

The use of prazosin for the treatment of trauma nightmares and sleep disturbance in combat veterans with post-traumatic stress disorder

scientific article published in April 2007

Tiagabine increases slow-wave sleep in a dose-dependent fashion without affecting traditional efficacy measures in adults with primary insomnia.

scientific article published in January 2006

Treatment of insomnia in depressed insomniacs: effects on health-related quality of life, objective and self-reported sleep, and depression ⬇️

scientific article published on August 15, 2010

Using difficulty resuming sleep to define nocturnal awakenings

scientific article

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