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List of works by James Bain

"Prediction is very hard, especially about the future": new biomarkers for type 2 diabetes?

scientific article published on May 2013

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

scientific article (publication date: April 2009)

A cell non-autonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism

scientific article published on 26 November 2020

A lipidomics analysis of the relationship between dietary fatty acid composition and insulin sensitivity in young adults

scientific article published on 13 December 2012

Adverse Effects of Fenofibrate in Mice Deficient in the Protein Quality Control Regulator, CHIP

article

An adenovirus vector for efficient RNA interference-mediated suppression of target genes in insulinoma cells and pancreatic islets of langerhans

scientific article published on September 2004

Analysis of serum metabolic profiles in women with endometrial cancer and controls in a population-based case-control study

scientific article

Association of Plasma Small-Molecule Intermediate Metabolites With Age and Body Mass Index Across Six Diverse Study Populations.

scientific article

Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events

scientific article published on 19 February 2010

Baseline metabolomic profiles predict cardiovascular events in patients at risk for coronary artery disease

scientific article published in May 2012

Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness

scientific article published on February 2013

Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss ⬇️

scientific article published on November 8, 2011

Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export

scientific article (publication date: July 2016)

Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial

scientific article

Cardiomyocyte-Specific Human Bcl2-Associated Anthanogene 3 P209L Expression Induces Mitochondrial Fragmentation, Bcl2-Associated Anthanogene 3 Haploinsufficiency, and Activates p38 Signaling

scientific article

Cessation of biomechanical stretch model of C2C12 cells models myocyte atrophy and anaplerotic changes in metabolism using non-targeted metabolomics analysis

scientific article published on 8 August 2016

Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis

scientific article published in March 2007

Correction: Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling

scientific article

Daily Variation of Serum Acylcarnitines and Amino Acids

scientific article

Dietary intake of palmitate and oleate has broad impact on systemic and tissue lipid profiles in humans

scientific article published on 15 January 2014

Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss

scientific article published on April 2011

Disrupted Maturation of the Microbiota and Metabolome among Extremely Preterm Infants with Postnatal Growth Failure.

scientific article published on 3 June 2019

Dissecting the in vivo metabolic potential of two human gut acetogens

scientific article

Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver

article

Effect of aerobic training on the host systemic milieu in patients with solid tumours: an exploratory correlative study.

scientific article published on 13 January 2015

Effect of caloric restriction with and without exercise on metabolic intermediates in nonobese men and women

scientific article

Effect of heparin administration on metabolomic profiles in samples obtained during cardiac catheterization

scientific article

Exercise-Induced Alterations in Skeletal Muscle, Heart, Liver, and Serum Metabolome Identified by Non-Targeted Metabolomics Analysis.

scientific article published on 8 August 2017

Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity. ⬇️

scientific article

Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice

scientific article

Feasibility of Localized Metabolomics in the Study of Pancreatic Islets and Diabetes

scientific article published on 29 September 2019

Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling

scientific article

Glycophase glass revisited: protein adsorption and cell growth on glass surfaces bearing immobilized glycerol monosaccharides

scientific article published in August 2002

Growth and Function of Transgenic Endocrine Cells on Silanized Surfaces ⬇️

doctoral thesis by James Raymond Bain, University of Washington, 2001

Gut microbiota from twins discordant for obesity modulate metabolism in mice

scientific article (publication date: 6 September 2013)

High heritability of metabolomic profiles in families burdened with premature cardiovascular disease

scientific article published on 07 April 2009

Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans

scientific article published on 9 August 2015

Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle

scientific article

Leptin therapy in insulin-deficient type I diabetes

scientific article

Loss of SIRT3 leads to a compensatory shift in cellular metabolism promoting cancer cell growth.

scientific article published on 28 May 2014

Marginal vitamin B-6 deficiency decreases plasma (n-3) and (n-6) PUFA concentrations in healthy men and women

scientific article

Metabolic Networks and Metabolites Underlie Associations Between Maternal Glucose During Pregnancy and Newborn Size at Birth.

scientific article published on 05 April 2016

Metabolic profiling in Prader-Willi syndrome and nonsyndromic obesity: sex differences and the role of growth hormone

scientific article

Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure

scientific article published on 29 July 2016

Metabolomic Quantitative Trait Loci (mQTL) Mapping Implicates the Ubiquitin Proteasome System in Cardiovascular Disease Pathogenesis

scientific article published on 5 November 2015

Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion.

scientific article published on 23 March 2009

Metabolomics applied to diabetes research: moving from information to knowledge

scientific article

Metabolomics reveals broad-scale metabolic perturbations in hyperglycemic mothers during pregnancy

scientific article published on 29 August 2013

Metabolomics reveals unexpected responses to oral glucose

scientific article published on August 2013

Metabomxtr: an R package for mixture-model analysis of non-targeted metabolomics data

scientific article

Mig-6 plays a critical role in the regulation of cholesterol homeostasis and bile acid synthesis.

scientific article

Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance

scientific article published on January 2008

MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet

scientific article published on 5 August 2015

Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet.

scientific article published on 28 July 2015

Non-Targeted Metabolomics Analysis of the Effects of Tyrosine Kinase Inhibitors Sunitinib and Erlotinib on Heart, Muscle, Liver and Serum Metabolism In Vivo.

scientific article published on 22 June 2017

Non-targeted metabolomics of Brg1/Brm double-mutant cardiomyocytes reveals a novel role for SWI/SNF complexes in metabolic homeostasis

scientific article

Non-targeted urinary metabolomics in pregnancy and associations with fetal growth restriction

scientific article published on 24 March 2020

Pathogenesis of A⁻β⁺ ketosis-prone diabetes

scientific article published on 16 November 2012

Plasma acylcarnitines are associated with physical performance in elderly men

scientific article

Proteomic Profiling Reveals Adaptive Responses to Surgical Myocardial Ischemia-Reperfusion in Hibernating Arctic Ground Squirrels Compared to Rats

scientific article published on June 2016

Race and sex differences in small-molecule metabolites and metabolic hormones in overweight and obese adults

scientific article published on 11 October 2013

Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium.

scientific article

Recommendations for Improving Identification and Quantification in Non-Targeted, GC-MS-Based Metabolomic Profiling of Human Plasma

scientific article published on 25 August 2017

Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women

scientific article published on 05 June 2009

Research Resource: Roles for Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) in Systems Metabolism

scientific article published on 22 March 2016

Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family

scientific article published on 11 January 2013

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

scientific article

Severe acute malnutrition in childhood: hormonal and metabolic status at presentation, response to treatment, and predictors of mortality

scientific article

Sex differences in biomarkers associated with insulin resistance in obese adolescents: metabolomic profiling and principal components analysis

scientific article

Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition.

scientific article published on 17 February 2016

Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation

scientific article published on 08 July 2013

Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization

scientific article

TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism

scientific article

Targeted Metabolomics Finds Its Mark in Diabetes Research ⬇️

scientific article published on February 1, 2013

The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain

scientific article published on February 2009

The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) weight loss project: Rationale and design

scientific article published on 18 October 2005

The coactivator SRC-1 is an essential coordinator of hepatic glucose production.

scientific article published on December 2010

The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins

scientific article published in October 2011

Tissue-culture surfaces with mixtures of aminated and fluorinated functional groups. Part 1. Synthesis and characterization

scientific article published in January 2003

Tissue-culture surfaces with mixtures of aminated and fluorinated functional groups. Part 2. Growth and function of transgenic rat insulinoma cells (betaG I/17).

scientific article published in January 2003

Validation of the association between a branched chain amino acid metabolite profile and extremes of coronary artery disease in patients referred for cardiac catheterization

scientific article published on 12 November 2013

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