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List of works by Paulo A. Ferreira

Bovine phospholipase C highly homologous to the norpA protein of Drosophila is expressed specifically in cones.

scientific article published in February 1994

Characterization of RanBP2-associated molecular components in neuroretina

scientific article published on 01 January 2000

Correction to: The coming-of-age of nucleocytoplasmic transport in motor neuron disease and neurodegeneration

scientific article published on 01 June 2019

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis

scientific article published on 08 January 2014

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

scientific article

Evidence for RPGRIP1 gene as risk factor for primary open angle glaucoma

scientific article

FromDrosophilato Humans: Reflections on the Roles of the Prolyl Isomerases and Chaperones, Cyclophilins, in Cell Function and Disease ⬇️

scientific article published on February 14, 2012

Gene and protein expression pilot profiling and biomarkers in an experimental mouse model of hypertensive glaucoma

scientific article published on 2 June 2009

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons

scientific article

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization

scientific article

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I

scientific article published on 6 September 2017

Insights into X-linked retinitis pigmentosa type 3, allied diseases and underlying pathomechanisms

scientific article

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2

scientific article

Isolation of retinal proteins that interact with retinitis pigmentosa GTPase regulator by interaction trap screen in yeast

scientific article published on 01 January 2000

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

scientific article published on 27 March 2013

Limited proteolysis differentially modulates the stability and subcellular localization of domains of RPGRIP1 that are distinctly affected by mutations in Leber's congenital amaurosis

scientific article

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes

scientific article

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons

scientific article published on 03 April 2019

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress

scientific article

RANBP2 is an allosteric activator of the conventional kinesin-1 motor protein, KIF5B, in a minimal cell-free system

scientific article

RPGRIP1 is essential for normal rod photoreceptor outer segment elaboration and morphogenesis

scientific article published on 13 August 2009

RPGRIP1s with distinct neuronal localization and biochemical properties associate selectively with RanBP2 in amacrine neurons

scientific article published in August 2003

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism ⬇️

scientific article

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

scientific article

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

scientific article

Selective loss of RPGRIP1-dependent ciliary targeting of NPHP4, RPGR and SDCCAG8 underlies the degeneration of photoreceptor neurons

scientific article

Species-specific subcellular localization of RPGR and RPGRIP isoforms: implications for the phenotypic variability of congenital retinopathies among species

scientific article

Structural and functional plasticity of subcellular tethering, targeting and processing of RPGRIP1 by RPGR isoforms ⬇️

scientific article published on December 30, 2011

Targeting the cyclophilin domain of Ran-binding protein 2 (Ranbp2) with novel small molecules to control the proteostasis of STAT3, hnRNPA2B1 and M-opsin.

scientific article

The coming-of-age of nucleocytoplasmic transport in motor neuron disease and neurodegeneration

scientific article published on 11 February 2019

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

scientific article published in September 1998

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

scientific article published on 11 September 2001

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1

scientific article (publication date: 24 December 1999)

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

scientific article published on 26 November 2015

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