Search filters

List of works by Paolo Pinton

17β-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells

scientific article

A calcium signaling defect in the pathogenesis of a mitochondrial DNA inherited oxidative phosphorylation deficiency

scientific article published on August 1999

A family with paroxysmal nonkinesigenic dyskinesias (PNKD): evidence of mitochondrial dysfunction

scientific article published on 18 October 2014

A mitochondrial drug to treat AML.

scientific article published in May 2017

A novel Ca²⁺-mediated cross-talk between endoplasmic reticulum and acidic organelles: implications for NAADP-dependent Ca²⁺ signalling

scientific article published on 21 January 2015

A novel chimeric aequorin fused with caveolin-1 reveals a sphingosine kinase 1-regulated Ca²⁺ microdomain in the caveolar compartment.

scientific article published on 16 April 2015

A novel recombinant plasma membrane-targeted luciferase reveals a new pathway for ATP secretion

scientific article published on 8 June 2005

A role for calcium in Bcl-2 action?

scientific article

A unified nomenclature and amino acid numbering for human PTEN.

scientific article

ATP synthesis and storage

scientific article

Accelerated Tumor Progression in Mice Lacking the ATP Receptor P2X7

Adipose tissue regeneration: a state of the art.

scientific article

Aequorin chimeras as valuable tool in the measurement of Ca2+ concentration during cadmium injury

scientific article published on March 2005

Age-related changes in levels of p66Shc and serine 36-phosphorylated p66Shc in organs and mouse tissues

scientific article

Akt kinase reducing endoplasmic reticulum Ca2+ release protects cells from Ca2+-dependent apoptotic stimuli

scientific article published on 22 August 2008

Akt-mediated phosphorylation of MICU1 regulates mitochondrial Ca2+ levels and tumor growth

scientific article published on 30 November 2018

Alterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 Mutants

scientific article

Alterations of calcium homeostasis in cancer cells

scientific article published on April 2016

Amyloid-beta disrupts calcium and redox homeostasis in brain endothelial cells

scientific article published on 16 May 2014

An expanded palette of improved SPLICS reporters detects multiple organelle contacts in vitro and in vivo

scientific article published on 27 November 2020

Aortic Valve Stenosis and Mitochondrial Dysfunctions: Clinical and Molecular Perspectives

scientific article published on 11 July 2020

Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy

scientific article published on 30 September 2020

Aspirin delays mesothelioma growth by inhibiting HMGB1-mediated tumor progression

scientific article

Autophagy and mitophagy biomarkers are reduced in sera of patients with Alzheimer's disease and mild cognitive impairment

scientific article published on 27 December 2019

Autophagy and mitophagy elements are increased in body fluids of multiple sclerosis-affected individuals

scientific article published on 2 September 2017

Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth

scientific article

Bcl-2 and Bax exert opposing effects on Ca2+ signaling, which do not depend on their putative pore-forming region

scientific article published on 12 October 2004

Bcl-2 and Ca2+ homeostasis in the endoplasmic reticulum

scientific article

Berberine slows cell growth in autosomal dominant polycystic kidney disease cells

scientific article published on 31 October 2013

Biosensors for the detection of calcium and pH.

scientific article published on January 2007

Ca(2+) transfer from the ER to mitochondria: when, how and why

scientific article

Ca2+ signaling, mitochondria and cell death

scientific article published on March 2008

Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

scientific article published on October 2008

Calcium and apoptosis: facts and hypotheses

scientific article published on November 2003

Calcium levels in the Golgi complex regulate clustering and apical sorting of GPI-APs in polarized epithelial cells

scientific article published in 2021

Calcium regulates cell death in cancer: Roles of the mitochondria and mitochondria-associated membranes (MAMs).

scientific article published on 10 January 2017

Calcium signaling around Mitochondria Associated Membranes (MAMs). ⬇️

scientific article published on 22 September 2011

Cancer therapy: Altering mitochondrial properties

scientific article published on 01 February 2014

Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function

scientific article

Cardiac mitochondrial dysfunction during hyperglycemia--the role of oxidative stress and p66Shc signaling

scientific article published on 07 July 2012

Cellular processes underlying cerebral cavernous malformations: Autophagy as another point of view

scientific article published on February 2016

Chemoresistance and Cancer-Related Inflammation: Two Hallmarks of Cancer Connected by an Atypical Link, PKCζ

scientific article

Chondrocyte protein with a poly-proline region (CHPPR) is a novel mitochondrial protein and promotes mitochondrial fission

scientific article published on 01 December 2004

Chronic pro-oxidative state and mitochondrial dysfunctions are more pronounced in fibroblasts from Down syndrome foeti with congenital heart defects

scientific article published on 20 December 2012

Clinical benefit of drugs targeting mitochondrial function as an adjunct to reperfusion in ST-segment elevation myocardial infarction: A meta-analysis of randomized clinical trials.

scientific article

Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca 2+ Responses ⬇️

scientific article (publication date: 12 June 1998)

Comprehensive analysis of mitochondrial permeability transition pore activity in living cells using fluorescence-imaging-based techniques

scientific article

Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine

article

Constitutive IP signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP receptor disruptor BIRD-2

scientific article published on 13 June 2018

Controlling metabolism and cell death: at the heart of mitochondrial calcium signalling

scientific article published on 12 March 2009

Correlation between auto/mitophagic processes and magnetic resonance imaging activity in multiple sclerosis patients

scientific article published on 27 June 2019

Data on administration of cyclosporine, nicorandil, metoprolol on reperfusion related outcomes in ST-segment Elevation Myocardial Infarction treated with percutaneous coronary intervention

scientific article published on 18 July 2017

Defective autophagy is a key feature of cerebral cavernous malformations

scientific article

Defective endoplasmic reticulum-mitochondria contacts and bioenergetics in SEPN1-related myopathy

scientific article published on 13 July 2020

Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo

scientific article published on 11 September 2019

Dense core secretory vesicles revealed as a dynamic Ca(2+) store in neuroendocrine cells with a vesicle-associated membrane protein aequorin chimaera.

scientific article

Differential expression of microRNA501-5p affects the aggressiveness of clear cell renal carcinoma

scientific article published on 4 November 2014

Differential recruitment of PKC isoforms in HeLa cells during redox stress

scientific article

Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction

scientific article published on 09 August 2018

Disrupted ATP synthase activity and mitochondrial hyperpolarisation-dependent oxidative stress is associated with p66Shc phosphorylation in fibroblasts of NARP patients

scientific article published on 31 July 2012

Donor age-related biological properties of human dental pulp stem cells change in nanostructured scaffolds

scientific article

Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson's disease

scientific article published on 12 February 2018

Double inhibition of cAMP and mTOR signalling may potentiate the reduction of cell growth in ADPKD cells

scientific article published on 9 June 2016

Downregulation of the mitochondrial calcium uniporter by cancer-related miR-25

scientific article published on 13 December 2012

Dynamics of glucose-induced membrane recruitment of protein kinase C beta II in living pancreatic islet beta-cells

scientific article

ER functions of oncogenes and tumor suppressors: Modulators of intracellular Ca(2+) signaling

scientific article

Editorial overview: Cancer

scientific article published on 29 July 2016

Efficacy of magnesium chloride in the treatment of Hailey-Hailey disease: from serendipity to evidence of its effect on intracellular Ca2+homeostasis

scientific article published on 28 November 2014

Efficacy of magnesium chloride in the treatment of Hailey-Hailey disease: some further considerations

scientific article published on 31 October 2015

Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

article

Emerging molecular mechanisms in chemotherapy: Ca2+ signaling at the mitochondria-associated endoplasmic reticulum membranes

scientific article published on 28 February 2018

Endoplasmic Reticulum-Mitochondria Communication Through Ca2+ Signaling: The Importance of Mitochondria-Associated Membranes (MAMs).

scientific article published in January 2017

Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosis

scientific article published on 22 June 2007

Endoplasmic reticulum, Bcl-2 and Ca2+ handling in apoptosis

scientific article

Ero1α regulates Ca(2+) fluxes at the endoplasmic reticulum-mitochondria interface (MAM).

scientific article

Erratum: The metabolic co-regulator PGC1α suppresses prostate cancer metastasis

scientific article published on 01 June 2017

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

scientific article

Expression of polycystin-1 C-terminal fragment enhances the ATP-induced Ca2+ release in human kidney cells

scientific article published on February 2003

Expression of the P2X7 receptor increases the Ca2+ content of the endoplasmic reticulum, activates NFATc1, and protects from apoptosis

scientific article

Extracellular ATP causes ROCK I-dependent bleb formation in P2X7-transfected HEK293 cells

scientific journal article

Fo ATP synthase C subunit serum levels in patients with ST-segment Elevation Myocardial Infarction: Preliminary findings

scientific article published on 9 July 2016

Functional and structural alterations in the endoplasmic reticulum and mitochondria during apoptosis triggered by C2-ceramide and CD95/APO-1/FAS receptor stimulation

scientific article published on 24 November 2009

Germline BAP1 mutations induce a Warburg effect

scientific article

Guanosine diphosphate exerts a lower effect on superoxide release from mitochondrial matrix in the brains of uncoupling protein-2 knockout mice: new evidence for a putative novel function of uncoupling proteins as superoxide anion transporters

scientific article published on 12 October 2012

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

H-Ras-driven tumoral maintenance is sustained through caveolin-1-dependent alterations in calcium signaling.

scientific article published on 3 June 2013

High IGFBP2 expression correlates with tumor severity in pediatric rhabdomyosarcoma

scientific article

High glucose induces adipogenic differentiation of muscle-derived stem cells

scholarly article

High mitochondrial Ca2+ content increases cancer cell proliferation upon inhibition of mitochondrial permeability transition pore (mPTP)

scientific article published on 07 April 2019

Hyaluronan and fibrin biomaterial as scaffolds for neuronal differentiation of adult stem cells derived from adipose tissue and skin

scientific article published on 12 October 2011

Hyaluronic acid induces activation of the κ-opioid receptor

scientific article

Identification of PTEN at the ER and MAMs and its regulation of Ca(2+) signaling and apoptosis in a protein phosphatase-dependent manner

scientific article published on 28 June 2013

In vitro concurrent endothelial and osteogenic commitment of adipose-derived stem cells and their genomical analyses through comparative genomic hybridization array: novel strategies to increase the successful engraftment of tissue-engineered bone g

scientific article published on 10 June 2011

Increased reactive oxygen species (ROS) production and low catalase level in fibroblasts of a girl with MEGDEL association (Leigh syndrome, deafness, 3-methylglutaconic aciduria).

scientific article published in January 2011

Inhibitory interaction of the 14-3-3{epsilon} protein with isoform 4 of the plasma membrane Ca(2+)-ATPase pump

scientific article published on 26 August 2005

Inside the tumor: p53 modulates calcium homeostasis

scientific article published in January 2015

Interaction of Mitochondria with the Endoplasmic Reticulum and Plasma Membrane in Calcium Homeostasis, Lipid Trafficking and Mitochondrial Structure

scientific article

Intersection of mitochondrial fission and fusion machinery with apoptotic pathways: Role of Mcl-1.

scientific article published on 28 May 2016

Intracellular evaluation of ER targeting elucidates a mild form of inherited coagulation deficiency

scientific article

Intracellular readthrough of nonsense mutations by aminoglycosides in coagulation factor VII.

scientific article published on June 2006

Intramitochondrial calcium regulation by the FHIT gene product sensitizes to apoptosis

scientific article published on 21 July 2009

Intravital imaging reveals p53-dependent cancer cell death induced by phototherapy via calcium signaling

scientific article

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

scientific article published on 08 October 2009

Isolation of plasma membrane–associated membranes from rat liver

scientific article published on 16 January 2014

KRIT1 regulates the homeostasis of intracellular reactive oxygen species

scientific article

LonP1 Differently Modulates Mitochondrial Function and Bioenergetics of Primary Versus Metastatic Colon Cancer Cells

scientific article published on 09 July 2018

Long-term modulation of mitochondrial Ca2+ signals by protein kinase C isozymes

scientific article published on 19 April 2004

Mcl-1 involvement in mitochondrial dynamics is associated with apoptotic cell death

scientific article

Mechanistic Role of mPTP in Ischemia-Reperfusion Injury.

scientific article published on January 2017

Melatonin as a master regulator of cell death and inflammation: molecular mechanisms and clinical implications for newborn care

scientific article published on 08 April 2019

Metformin prevents glucose-induced protein kinase C-beta2 activation in human umbilical vein endothelial cells through an antioxidant mechanism

scientific article published in April 2005

Methods to Assess Mitochondrial Morphology in Mammalian Cells Mounting Autophagic or Mitophagic Responses.

scientific article published on 12 November 2016

Methods to monitor ROS production by fluorescence microscopy and fluorometry.

scientific article published in January 2014

Methods to monitor and compare mitochondrial and glycolytic ATP production

scientific article published in January 2014

Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases

scientific article published on 22 June 2018

Mitochondria as biosensors of calcium microdomains

scientific article

Mitochondria associated membranes (MAMs) as critical hubs for apoptosis

scientific article published on May 2011

Mitochondria in Multiple Sclerosis: Molecular Mechanisms of Pathogenesis

scientific article published on 28 September 2016

Mitochondria, calcium and cell death: a deadly triad in neurodegeneration

scientific article

Mitochondria-associated endoplasmic reticulum membranes in insulin signaling

scientific article published on 01 October 2014

Mitochondria-associated membranes (MAMs) and pathologies

scientific article published on 16 March 2018

Mitochondria-associated membranes (MAMs) as hotspot Ca(2+) signaling units

scientific article published on January 2012

Mitochondria-associated membranes: composition, molecular mechanisms, and physiopathological implications

scientific article published on 13 March 2015

Mitochondria-ros crosstalk in the control of cell death and aging

scientific article

Mitochondrial Ca(2+) Remodeling is a Prime Factor in Oncogenic Behavior

scientific article published on 25 June 2015

Mitochondrial Ca(2+) and apoptosis

scientific article published on 03 April 2012

Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis.

scientific article

Mitochondrial DNA keeps you young

scientific article published on 24 September 2018

Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death.

scientific article

Mitochondrial calcium homeostasis as potential target for mitochondrial medicine

scientific article published on 21 July 2011

Mitochondrial calcium uniporter complex modulation in cancerogenesis

scientific article published on 10 May 2019

Mitochondrial calcium uniporter, MiRNA and cancer: Live and let die.

scientific article

Mitochondrial functionality and metabolism in T cells from progressive multiple sclerosis patients

scientific article published on 16 August 2019

Mitochondrial permeability transition involves dissociation of F1FO ATP synthase dimers and C-ring conformation

scientific article published on 31 May 2017

Mitochondrial reactive oxygen species and inflammation: Molecular mechanisms, diseases and promising therapies

scientific article

Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation

scientific article published on 09 August 2011

Mitochondrial tolerance to drugs and toxic agents in ageing and disease

scientific article published on June 2011

Mitophagy and mitochondrial balance

scientific article

Mitophagy in Cardiovascular Diseases

scientific article published on 24 March 2020

Molecular Characterization of the Dominant-Negative Role of Cancer-Associated PTEN: Sometimes, Null is Better

scientific article published on 10 October 2014

Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury

scientific article

Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition

scientific article published on 14 April 2014

Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition.

scientific article

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

Mutations of C19orf12, coding for a transmembrane glycine zipper containing mitochondrial protein, cause mis-localization of the protein, inability to respond to oxidative stress and increased mitochondrial Ca²⁺.

scientific article

NF-kappaB activation is required for apoptosis in fibrocystin/polyductin-depleted kidney epithelial cells

scientific article

NRIP1/RIP140 siRNA-mediated attenuation counteracts mitochondrial dysfunction in Down syndrome

scientific article published on 3 April 2014

Nanoscale particle therapies for wounds and ulcers

scientific article published on June 2010

Nanotechnology to drive stem cell commitment

scientific article published on March 2013

Novel frontiers in calcium signaling: A possible target for chemotherapy

scientific article published on 29 May 2015

Novel insights into the mitochondrial permeability transition

scientific article published on January 2014

Novel role for polycystin-1 in modulating cell proliferation through calcium oscillations in kidney cells

scientific article published on 15 April 2008

Oncogenic and oncosuppressive signal transduction at mitochondria-associated endoplasmic reticulum membranes

scientific article published on April 2014

Osteogenic differentiation of human MSCs: Specific occupancy of the mitochondrial DNA by NFATc1 transcription factor

scientific article published on 5 May 2015

Overexpression of adenine nucleotide translocase reduces Ca2+ signal transmission between the ER and mitochondria.

scientific article published on 25 July 2006

Oxidative stress in cardiovascular diseases and obesity: role of p66Shc and protein kinase C.

scientific article published on 27 March 2013

Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders

scientific article published on 10 March 2010

PKC-β activation and pharmacologically induced weight gain during antipsychotic treatment

scientific article published in April 2011

PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia

scientific article published on 19 October 2020

PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development

scientific article published on 18 August 2016

PML regulates apoptosis at endoplasmic reticulum by modulating calcium release

scientific journal article

PRKCB/protein kinase C, beta and the mitochondrial axis as key regulators of autophagy

scientific article published on 11 June 2013

Peroxisomes as novel players in cell calcium homeostasis

scientific article

Perturbed mitochondrial Ca2+ signals as causes or consequences of mitophagy induction

scientific article published on 21 May 2013

Pharmacological Profile of Nociceptin/Orphanin FQ Receptors Interacting with G-Proteins and β-Arrestins 2.

scientific article published on 6 August 2015

Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis

scientific article published on 06 May 2020

Phospholipase C-β3 is a key modulator of IL-8 expression in cystic fibrosis bronchial epithelial cells

scientific article published on 16 March 2011

Physiopathology of the Permeability Transition Pore: Molecular Mechanisms in Human Pathology

scientific article published on 04 July 2020

Plasma membrane associated membranes (PAM) from Jurkat cells contain STIM1 protein is PAM involved in the capacitative calcium entry?

scientific article published on 19 July 2009

Polycystin-1 promotes PKCalpha-mediated NF-kappaB activation in kidney cells

scientific article published on 18 September 2006

Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc

scientific article published on 01 February 2007

Protein kinases and phosphatases in the control of cell fate

scientific article

Publisher Correction: The machineries, regulation and cellular functions of mitochondrial calcium.

scientific article published in November 2018

Recombinant aequorin and green fluorescent protein as valuable tools in the study of cell signalling

scientific article

Recombinant aequorin as tool for monitoring calcium concentration in subcellular compartments.

scientific article

Recombinant expression of the Ca(2+)-sensitive aspartate/glutamate carrier increases mitochondrial ATP production in agonist-stimulated Chinese hamster ovary cells

scientific article

Redox control of protein kinase C: cell- and disease-specific aspects

scientific article published on October 2010

Reduced loading of intracellular Ca(2+) stores and downregulation of capacitative Ca(2+) influx in Bcl-2-overexpressing cells.

scientific article published on March 2000

Regulation of Endoplasmic Reticulum-Mitochondria Ca2+ Transfer and Its Importance for Anti-Cancer Therapies

scientific article published on 31 August 2017

Regulation of autophagy by cytoplasmic p53

scientific article

Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic priming

scientific article published on November 1999

Rehabilitation Improves Mitochondrial Energetics in Progressive Multiple Sclerosis: The Significant Role of Robot-Assisted Gait Training and of the Personalized Intensity

scientific article published on 17 October 2020

Relation Between Mitochondrial Membrane Potential and ROS Formation

scientific article published on 01 January 2018

Relation between mitochondrial membrane potential and ROS formation.

scientific article

Reticulon 3-dependent ER-PM contact sites control EGFR nonclathrin endocytosis.

scientific article published in May 2017

Reversal of the glycolytic phenotype of primary effusion lymphoma cells by combined targeting of cellular metabolism and PI3K/Akt/ mTOR signaling.

scientific article published on 6 November 2015

Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings.

scientific article

Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition

scientific article

SEPN1, an endoplasmic reticulum-localized selenoprotein linked to skeletal muscle pathology, counteracts hyperoxidation by means of redox-regulating SERCA2 pump activity

scientific journal article

STAT3 Activities and Energy Metabolism: Dangerous Liaisons.

scientific article published on 31 July 2014

STAT3 can serve as a hit in the process of malignant transformation of primary cells

scientific article

STAT3 localizes to the ER, acting as a gatekeeper for ER-mitochondrion Ca2+ fluxes and apoptotic responses

scientific article published on 24 July 2018

Selective augmentation of stem cell populations in structural fat grafts for maxillofacial surgery

scientific article

Selective modulation of subtype III IP₃R by Akt regulates ER Ca²⁺ release and apoptosis

scientific article published on 3 May 2012

Shedding light on molecular mechanisms and identity of mPTP.

scientific article published on 12 October 2014

Silencing of mitochondrial Lon protease deeply impairs mitochondrial proteome and function in colon cancer cells

scientific article published on 25 August 2014

Sphingosine 1-phosphate receptors modulate intracellular Ca2+ homeostasis

scientific article published on 11 December 2006

Structural and functional link between the mitochondrial network and the endoplasmic reticulum

scientific article published on 21 April 2009

Subcellular calcium measurements in mammalian cells using jellyfish photoprotein aequorin-based probes.

scientific article

Susceptibility to cellular stress in PS1 mutant N2a cells is associated with mitochondrial defects and altered calcium homeostasis

scientific article published on 15 April 2020

Syndromic parkinsonism and dementia associated with OPA1 missense mutations

scientific article

Systemic elevation of PTEN induces a tumor-suppressive metabolic state

scientific article published on 6 March 2012

TFG binds LC3C to regulate ULK1 localization and autophagosome formation

scientific article published on 01 May 2021

Targeted recombinant aequorins: tools for monitoring [Ca2+] in the various compartments of a living cell

scientific article

Targeting the NLRP3 Inflammasome as a New Therapeutic Option for Overcoming Cancer

scientific article published in 2021

The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action

scientific article

The Golgi Ca2+-ATPase KlPmr1p function is required for oxidative stress response by controlling the expression of the heat-shock element HSP60 in Kluyveromyces lactis

scientific article

The Golgi apparatus is an inositol 1,4,5-trisphosphate-sensitive Ca2+ store, with functional properties distinct from those of the endoplasmic reticulum

scientific article published on September 1998

The P2X7 receptor directly interacts with the NLRP3 inflammasome scaffold protein

scientific article

The RED light is on! New tools for monitoring Ca2+ dynamics in the endoplasmic reticulum and mitochondria

scientific article published in November 2014

The coxsackievirus 2B protein suppresses apoptotic host cell responses by manipulating intracellular Ca2+ homeostasis.

scientific article published on 19 February 2004

The cytoplasmic C-terminus of polycystin-1 increases cell proliferation in kidney epithelial cells through serum-activated and Ca(2+)-dependent pathway(s).

scientific article published on 15 December 2004

The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition

scientific article published on 19 June 2015

The endoplasmic reticulum-mitochondria connection: one touch, multiple functions.

scientific article

The interplay between p66Shc, reactive oxygen species and cancer cell metabolism

scientific article

The machineries, regulation and cellular functions of mitochondrial calcium

scientific article published on 01 November 2018

The metabolic co-regulator PGC1α suppresses prostate cancer metastasis.

scientific article published on 23 May 2016

The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications

scientific article

The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation

scientific article

The mitochondrial permeability transition pore and cancer: molecular mechanisms involved in cell death

scientific article

The mitochondrial permeability transition pore is a dispensable element for mitochondrial calcium efflux

scientific article

The p13 protein of human T cell leukemia virus type 1 (HTLV-1) modulates mitochondrial membrane potential and calcium uptake

scientific article published on 25 February 2010

The prolyl-isomerase Pin1 activates the mitochondrial death program of p53

scientific article published on 31 August 2012

The role of PML in the control of apoptotic cell fate: a new key player at ER–mitochondria sites ⬇️

scientific article published on 08 April 2011

The selective inhibition of nuclear PKCζ restores the effectiveness of chemotherapeutic agents in chemoresistant cells

scientific article published on March 2012

The versatility of mitochondrial calcium signals: from stimulation of cell metabolism to induction of cell death

scientific article published on July 2008

Transglutaminase 2 contributes to apoptosis induction in Jurkat T cells by modulating Ca2+ homeostasis via cross-linking RAP1GDS1

scientific article

Translational readthrough of GLA nonsense mutations suggests dominant-negative effects exerted by the interaction of wild-type and missense variants

scientific article published on 15 October 2019

Translocation of signalling proteins to the plasma membrane revealed by a new bioluminescent procedure

scientific article

Tumor necrosis factor-α impairs oligodendroglial differentiation through a mitochondria-dependent process

scientific article

Use of luciferase probes to measure ATP in living cells and animals

scientific article

VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria.

scientific article published on July 2011

Various Aspects of Calcium Signaling in the Regulation of Apoptosis, Autophagy, Cell Proliferation, and Cancer

scientific article published on 06 November 2020

Vav1 is a crucial molecule in monocytic/macrophagic differentiation of myeloid leukemia-derived cells

scientific article published on 7 June 2011

Weight gain related to treatment with atypical antipsychotics is due to activation of PKC-β.

scientific article published on 22 December 2009

p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner

scientific article

p66Shc aging protein in control of fibroblasts cell fate

scientific article

pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant

scientific article

Paulina is supported by:

About Paulina

Help