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List of works by Saverio Francesco Retta

A de novo X;8 translocation creates a PTK2-THOC2 gene fusion with THOC2 expression knockdown in a patient with psychomotor retardation and congenital cerebellar hypoplasia

scientific journal article

A unique interplay between Rap1 and E-cadherin in the endocytic pathway regulates self-renewal of human embryonic stem cells

scientific article

Altered expression of integrins in RSV-transformed chick epiphyseal chondrocytes.

scientific article published in May 2003

Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies.

scientific article published on 25 January 2016

Biological Activities, Health Benefits, and Therapeutic Properties of Avenanthramides: From Skin Protection to Prevention and Treatment of Cerebrovascular Diseases

article

Cellular processes underlying cerebral cavernous malformations: Autophagy as another point of view

scientific article published on February 2016

Cerebral cavernous malformation (CCM) disease: from monogenic forms to genetic susceptibility factors

scientific article published on 21 April 2015

Combined pulldown and time-lapse microscopy studies for determining the role of Rap1 in the crosstalk between integrins and cadherins

scientific article published on January 2014

Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1.

scientific article published on 18 January 2016

Defective autophagy is a key feature of cerebral cavernous malformations

scientific article

Dicarbonyl Stress and S-Glutathionylation in Cerebrovascular Diseases: A Focus on Cerebral Cavernous Malformations

scientific article published on 01 February 2020

E-cadherin endocytosis regulates the activity of Rap1: a traffic light GTPase at the crossroads between cadherin and integrin function

scientific article published on October 2005

EndMT contributes to the onset and progression of cerebral cavernous malformations

scientific article published on 9 June 2013

Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast.

scientific article

Expression of beta 1B integrin isoform in CHO cells results in a dominant negative effect on cell adhesion and motility

scientific article

Fluorescence microscopy study of Rap1 subcellular localization

scientific article published on January 2014

Genetic and cellular basis of cerebral cavernous malformations: implications for clinical management

scientific article published on 08 May 2012

Helicobacter pylori type IV secretion apparatus exploits beta1 integrin in a novel RGD-independent manner

scientific article

Identification of Krit1B: a novel alternative splicing isoform of cerebral cavernous malformation gene-1.

scientific article published on January 2004

Identification of the Kelch family protein Nd1-L as a novel molecular interactor of KRIT1

scientific journal article

Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines

scientific article

Intracellular Antioxidant Activity of Biocompatible Citrate-Capped Palladium Nanozymes

scientific article published on 03 January 2020

KRIT1 Deficiency Promotes Aortic Endothelial Dysfunction

scientific article published on 05 October 2019

KRIT1 Loss-Of-Function Associated with Cerebral Cavernous Malformation Disease Leads to Enhanced -Glutathionylation of Distinct Structural and Regulatory Proteins

scientific article published on 17 January 2019

KRIT1 loss of function causes a ROS-dependent upregulation of c-Jun

scientific article published on 28 November 2013

KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease

scientific article published on 20 November 2017

KRIT1 regulates the homeostasis of intracellular reactive oxygen species

scientific article

Molecular Crosstalk between Integrins and Cadherins: Do Reactive Oxygen Species Set the Talk?

scientific article

Multifunctional Platinum@BSA–Rapamycin Nanocarriers for the Combinatorial Therapy of Cerebral Cavernous Malformation

scientific article published on 13 November 2018

Muscle beta1D integrin reinforces the cytoskeleton-matrix link: modulation of integrin adhesive function by alternative splicing.

scientific article published in December 1997

Mutation analysis of CCM1, CCM2 and CCM3 genes in a cohort of Italian patients with cerebral cavernous malformation

scientific article

Nuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation.

scientific article

Oxidative stress and inflammation in cerebral cavernous malformation disease pathogenesis: Two sides of the same coin.

scientific article published on 14 September 2016

Platinum nanozymes recover cellular ROS homeostasis in an oxidative stress-mediated disease model

scientific article published on 27 January 2016

Production of novel antioxidative phenolic amides through heterologous expression of the plant's chlorogenic acid biosynthesis genes in yeast.

scientific article published on 24 November 2009

Professional athletes and cerebral cavernomas: an obstacle to overcome

scientific article published on 18 March 2014

Protein kinase Cα regulates the nucleocytoplasmic shuttling of KRIT1

scientific article published on 04 February 2021

Ras GTPases are both regulators and effectors of redox agents

scientific article published on January 2014

Reactive oxygen species: friends and foes of signal transduction

scientific article published on 11 March 2012

RhoA activity is required for fibronectin assembly and counteracts beta1B integrin inhibitory effect in FRT epithelial cells.

scientific article published on March 1999

Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation.

scientific article

Structural and functional differences between KRIT1A and KRIT1B isoforms: a framework for understanding CCM pathogenesis.

scientific article

The Interplay between ROS and Ras GTPases: Physiological and Pathological Implications.

scientific article published on 30 November 2011

The Ras superfamily of small GTPases: the unlocked secrets

scientific article

The integrin cytoplasmic domain-associated protein ICAP-1 binds and regulates Rho family GTPases during cell spreading

scientific article

The muscle-specific laminin receptor alpha7 beta1 integrin negatively regulates alpha5 beta1 fibronectin receptor function

scientific article published on February 1999

Towards precision nanomedicine for cerebrovascular diseases with emphasis on Cerebral Cavernous Malformation (CCM)

scientific article published on 06 January 2021

Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium.

scientific article

Vitamin D Deficiency and the Risk of Cerebrovascular Disease

scientific article published on 17 April 2020

Yeast-Derived Recombinant Avenanthramides Inhibit Proliferation, Migration and Epithelial Mesenchymal Transition of Colon Cancer Cells

scientific article published on 24 August 2018

Yersinia enterocolitica exploits different pathways to accomplish adhesion and toxin injection into host cells.

scientific article published on 20 March 2015

beta1D integrin inhibits cell cycle progression in normal myoblasts and fibroblasts

scientific article published on June 1998

miR-21 coordinates tumor growth and modulates KRIT1 levels

scientific article published on 18 July 2013

p125FAK tyrosine phosphorylation and focal adhesion assembly: studies with phosphotyrosine phosphatase inhibitors

scientific article published in November 1995

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