List of works - Roberto Piva

15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis in human malignant B cells: an effect associated with inhibition of NF-kappa B activity and down-regulation of antiapoptotic proteins.

scientific article

A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation

scientific article published on 23 December 2014

ALK Signaling and Target Therapy in Anaplastic Large Cell Lymphoma

scientific article published in 2012

ALK expression favorably impacts the prognosis of NRAS-mutated metastatic melanomas

scientific article published on 09 October 2018

ALK-dependent control of hypoxia-inducible factors mediates tumor growth and metastasis.

scientific article published on 5 September 2014

Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas

scientific article published on 27 September 2005

Anaplastic large cell lymphoma: one or more entities among T-cell lymphoma?

scientific article published on December 2009

Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death

scientific article (publication date: 7 February 2002)

Author Correction: Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension

scientific article published on 30 June 2020

CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib

scientific article published on 5 December 2007

Cell-cycle inhibitor p27/Kip-1 expression in non-astrocytic and non-oligodendrocytic human nervous system tumors.

scientific article published in April 1999

Characterization of murine Girk2 transcript isoforms: structure and differential expression

scientific article published in August 1998

Convergent Mutations and Kinase Fusions Lead to Oncogenic STAT3 Activation in Anaplastic Large Cell Lymphoma

Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.

scientific article

Cyclin D1 expression in gliomas

scientific article published in February 1998

Deregulation of ETS1 and FLI1 contributes to the pathogenesis of diffuse large B-cell lymphoma

scientific article

Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes.

scientific article

Gelsius: a literature-based workflow for determining quantitative associations between genes and biological processes

scientific article published on May 2013

Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms

scientific article

Heat stress triggers apoptosis by impairing NF-kappaB survival signaling in malignant B cells

scientific article

Hypoxia transcriptionally induces macrophage-inflammatory protein-3alpha/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kappaB.

scientific article published on 18 December 2007

IDH2 inhibition enhances proteasome inhibitor responsiveness in hematological malignancies

scientific article published on 19 November 2018

IL-6, but not IFN-gamma, triggers apoptosis and inhibits in vivo growth of human malignant T cells on STAT3 silencing.

scientific article

IRF4 Mediates the Oncogenic Effects of STAT3 in Anaplastic Large Cell Lymphomas.

scientific article published on 18 January 2018

Identification and Validation of the Anaplastic Large Cell Lymphoma Signature

scientific article published on 01 January 2007

Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma

scientific article

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

scientific article

Induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: role of the IkappaB kinase/nuclear factor-kappaB pathway

scientific article published on 14 August 2006

Integrated DNA copy number and methylation profiling of lymphoid neoplasms using a single array

scientific article published on 25 November 2011

Inverse relationship between p27/Kip.1 and the F-box protein Skp2 in human astrocytic gliomas by immunohistochemistry and Western blot

scientific article

Lack of apoptosis in mice with ALS

scientific article published on 01 September 1999

Lentiviral vectors carrying enhancer elements of Hb9 promoter drive selective transgene expression in mouse spinal cord motor neurons.

scientific article published on 8 January 2012

Low expression of p27 and low proliferation index do not correlate in hairy cell leukaemia

scientific article published on 01 October 2000

MicroRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma

scientific article published on 25 June 2013

Molecular events underlying interleukin-6 independence in a subclone of the CMA-03 multiple myeloma cell line

scientific article published on 5 November 2013

Molecular profiling improves classification and prognostication of nodal peripheral T-cell lymphomas: results of a phase III diagnostic accuracy study.

scientific article published on 15 July 2013

Mutations in NOTCH1 PEST-domain orchestrate CCL19-driven homing of Chronic Lymphocytic Leukemia cells by modulating the tumor suppressor gene DUSP22.

scientific article published on 26 December 2016

NAMPT Over-Expression Recapitulates the BRAF Inhibitor Resistant Phenotype Plasticity in Melanoma

scientific article published on 20 December 2020

NF-kappaB: a stress-regulated switch for cell survival.

scientific article

NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors.

scientific article published on 7 November 2002

Nuclear Akt2 opposes limbal keratinocyte stem cell self-renewal by repressing a FOXO-mTORC1 signaling pathway.

scientific article published on March 2014

PD-L1 up-regulation in melanoma increases disease aggressiveness and is mediated through miR-17-5p

scientific article published on 09 February 2017

PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas

scientific article

PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma

scientific article published on 4 September 2013

Pathobiology of anaplastic large cell lymphoma

scientific article published on January 2010

Role of apoptosis in the prognosis of oligodendrogliomas

scientific article published in August 1997

S-100β protein is upregulated in astrocytes and motor neurons in the spinal cord of patients with amyotrophic lateral sclerosis

scientific article published on 01 February 1999

SLAMF1 regulation of chemotaxis and autophagy determines CLL patient response

scientific article published on 30 November 2015

STAT3-mediated activation of microRNA cluster 17~92 promotes proliferation and survival of ALK-positive anaplastic large cell lymphoma

scientific article published on 23 August 2013

Specific induction of Akt3 in spinal cord motor neurons is neuroprotective in a mouse model of familial amyotrophic lateral sclerosis.

scientific article

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.

scientific article published on 28 March 2018

The Krüppel-like factor 2 transcription factor gene is recurrently mutated in splenic marginal zone lymphoma.

scientific article published on 6 October 2014

The RNA-binding protein ESRP1 promotes human colorectal cancer progression

scientific article published on 28 December 2016

The anaplastic lymphoma kinase in the pathogenesis of cancer

scientific article published on January 2008

The heterogeneous landscape of ALK negative ALCL.

scientific article

Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension

scientific article published on 04 March 2020

Transposable elements: The enemies within.

scientific article

Wild-Type IDH Enzymes as Actionable Targets for Cancer Therapy

scientific article published on 19 April 2019

bcl-2 protein expression in aged brain and neurodegenerative diseases

scientific article published on 01 October 1994

p130Cas mediates the transforming properties of the anaplastic lymphoma kinase

scientific article

p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity

scientific article

p27/kip1 expression in human astrocytic gliomas.

scientific article published in October 1997

p27/kip1 expression in oligodendrogliomas and its possible prognostic role.

scientific article published in December 1999

List of works by Roberto Piva

15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis in human malignant B cells: an effect associated with inhibition of NF-kappa B activity and down-regulation of antiapoptotic proteins.

A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation

ALK Signaling and Target Therapy in Anaplastic Large Cell Lymphoma

ALK expression favorably impacts the prognosis of NRAS-mutated metastatic melanomas

ALK-dependent control of hypoxia-inducible factors mediates tumor growth and metastasis.

Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas

Anaplastic large cell lymphoma: one or more entities among T-cell lymphoma?

Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death

Author Correction: Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension

CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib

Cell-cycle inhibitor p27/Kip-1 expression in non-astrocytic and non-oligodendrocytic human nervous system tumors.

Characterization of murine Girk2 transcript isoforms: structure and differential expression

Convergent Mutations and Kinase Fusions Lead to Oncogenic STAT3 Activation in Anaplastic Large Cell Lymphoma

Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma.

Cyclin D1 expression in gliomas

Deregulation of ETS1 and FLI1 contributes to the pathogenesis of diffuse large B-cell lymphoma

Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes.

Gelsius: a literature-based workflow for determining quantitative associations between genes and biological processes

Gene expression profiling uncovers molecular classifiers for the recognition of anaplastic large-cell lymphoma within peripheral T-cell neoplasms

Heat stress triggers apoptosis by impairing NF-kappaB survival signaling in malignant B cells

Hypoxia transcriptionally induces macrophage-inflammatory protein-3alpha/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kappaB.

IDH2 inhibition enhances proteasome inhibitor responsiveness in hematological malignancies

IL-6, but not IFN-gamma, triggers apoptosis and inhibits in vivo growth of human malignant T cells on STAT3 silencing.

IRF4 Mediates the Oncogenic Effects of STAT3 in Anaplastic Large Cell Lymphomas.

Identification and Validation of the Anaplastic Large Cell Lymphoma Signature

Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

Induction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: role of the IkappaB kinase/nuclear factor-kappaB pathway

Integrated DNA copy number and methylation profiling of lymphoid neoplasms using a single array

Inverse relationship between p27/Kip.1 and the F-box protein Skp2 in human astrocytic gliomas by immunohistochemistry and Western blot

Lack of apoptosis in mice with ALS

Lentiviral vectors carrying enhancer elements of Hb9 promoter drive selective transgene expression in mouse spinal cord motor neurons.

Low expression of p27 and low proliferation index do not correlate in hairy cell leukaemia

MicroRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma

Molecular events underlying interleukin-6 independence in a subclone of the CMA-03 multiple myeloma cell line

Molecular profiling improves classification and prognostication of nodal peripheral T-cell lymphomas: results of a phase III diagnostic accuracy study.

Mutations in NOTCH1 PEST-domain orchestrate CCL19-driven homing of Chronic Lymphocytic Leukemia cells by modulating the tumor suppressor gene DUSP22.

NAMPT Over-Expression Recapitulates the BRAF Inhibitor Resistant Phenotype Plasticity in Melanoma

NF-kappaB: a stress-regulated switch for cell survival.

NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors.

Nuclear Akt2 opposes limbal keratinocyte stem cell self-renewal by repressing a FOXO-mTORC1 signaling pathway.

PD-L1 up-regulation in melanoma increases disease aggressiveness and is mediated through miR-17-5p

PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas

PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma

Pathobiology of anaplastic large cell lymphoma

Role of apoptosis in the prognosis of oligodendrogliomas

S-100β protein is upregulated in astrocytes and motor neurons in the spinal cord of patients with amyotrophic lateral sclerosis

SLAMF1 regulation of chemotaxis and autophagy determines CLL patient response

STAT3-mediated activation of microRNA cluster 17~92 promotes proliferation and survival of ALK-positive anaplastic large cell lymphoma

Specific induction of Akt3 in spinal cord motor neurons is neuroprotective in a mouse model of familial amyotrophic lateral sclerosis.

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.

The Krüppel-like factor 2 transcription factor gene is recurrently mutated in splenic marginal zone lymphoma.

The RNA-binding protein ESRP1 promotes human colorectal cancer progression

The anaplastic lymphoma kinase in the pathogenesis of cancer

The heterogeneous landscape of ALK negative ALCL.

Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension

Transposable elements: The enemies within.

Wild-Type IDH Enzymes as Actionable Targets for Cancer Therapy

bcl-2 protein expression in aged brain and neurodegenerative diseases

p130Cas mediates the transforming properties of the anaplastic lymphoma kinase

p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity

p27/kip1 expression in human astrocytic gliomas.

p27/kip1 expression in oligodendrogliomas and its possible prognostic role.