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List of works by John L. Bixby

96-well electroporation method for transfection of mammalian central neurons

scientific article published on November 2006

A chemical genetic approach identifies piperazine antipsychotics as promoters of CNS neurite growth on inhibitory substrates.

scientific article

A neuronal inhibitory domain in the N-terminal half of agrin

scientific article published on 01 February 2002

A new in vitro model of the glial scar inhibits axon growth

scientific article

A novel substrate of receptor tyrosine phosphatase PTPRO is required for nerve growth factor-induced process outgrowth

scientific journal article

Agrin orchestrates synaptic differentiation at the vertebrate neuromuscular junction

scientific article published on January 1998

BMP growth factors and Phox2 transcription factors can induce synaptotagmin I and neurexin I during sympathetic neuron development

scientific article

CRYP-2: a receptor-type tyrosine phosphatase selectively expressed by developing vertebrate neurons

scientific article

Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models

scientific article published on 01 April 2019

Challenges in Small Screening Laboratories: Implementing an On-Demand Laboratory Information Management System ⬇️

scientific article published on November 1, 2011

Chemical interrogation of the neuronal kinome using a primary cell-based screening assay

scientific article

Collagen synthesis inhibition reduces clustering of heparan sulfate proteoglycan and acetylcholine receptors but not agrin or p65, at neuromuscular contacts in vitro

scientific article published in February 1995

Differential activities in adhesion and neurite growth of fibronectin type III repeats in the PTP-delta extracellular domain

scientific article

Distinct neurite outgrowth signaling pathways converge on ERK activation

scientific article published on May 1999

Dyrk kinases regulate phosphorylation of doublecortin, cytoskeletal organization, and neuronal morphology

scientific article

EST Express: PHP/MySQL based automated annotation of ESTs from expression libraries

scientific article

Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling

scientific article published on 21 December 2020

Exploiting kinase polypharmacology for nerve regeneration.

scientific article published on January 2016

Expression of PTPRO during mouse development suggests involvement in axonogenesis and differentiation of NT-3 and NGF-dependent neurons

scientific article published in February 2003

Expression of PTPRO in the interneurons of adult mouse olfactory bulb

scientific journal article

Expression of neuronal markers suggests heterogeneity of chick sympathoadrenal cells prior to invasion of the adrenal anlagen

scientific article published on 25 November 2004

Facilitating transparency in spinal cord injury studies using data standards and ontologies

scientific article

Fibroblast growth factor receptor signaling in Xenopus retinal axon extension

scientific article published in December 1998

Glycosaminoglycan-dependent and -independent inhibition of neurite outgrowth by agrin

scientific article published in July 2004

Growth cone steering by receptor tyrosine phosphatase delta defines a distinct class of guidance cue

scientific article published on 01 November 2000

High content screening of cortical neurons identifies novel regulators of axon growth

scientific article

High-content analysis of proapoptotic EphA4 dependence receptor functions using small-molecule libraries.

scientific article

Inhibition of GCK-IV kinases dissociates cell death and axon regeneration in CNS neurons

scientific article published on 14 December 2020

Inhibition of tyrosine phosphorylation potentiates substrate-induced neurite growth

scientific article published in July 1992

Interaction of an intracellular pentraxin with a BTB-Kelch protein is associated with ubiquitylation, aggregation and neuronal apoptosis

scientific journal article

Isoform diversity and its importance for axon regeneration.

scientific article published on 13 December 2011

Isoform diversity and regulation in peripheral and central neurons revealed through RNA-Seq

scientific article published in 2012

KLF family members regulate intrinsic axon regeneration ability.

scientific article

Kinase/phosphatase overexpression reveals pathways regulating hippocampal neuron morphology.

scientific article

Krüppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract ⬇️

scientific article published on April 23, 2012

MicroRNAs and neuronal development

scientific article

Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury ⬇️

scientific article published on January 27, 2011

Motor neurite outgrowth is selectively inhibited by cell surface MuSK and agrin.

scientific article published on February 2005

Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism.

scientific article

Neuronal pentraxin with chromo domain (NPCD) is a novel class of protein expressed in multiple neuronal domains

scientific journal article

Patterns of presynaptic gene expression define two stages of synaptic differentiation

scientific article

Paxillin phosphorylation counteracts proteoglycan-mediated inhibition of axon regeneration

scientific article published on 21 June 2013

Peripheral nervous system genes expressed in central neurons induce growth on inhibitory substrates.

scientific article

Protein Tyrosine Phosphatase Receptor Type O Inhibits Trigeminal Axon Growth and Branching by Repressing TrkB and Ret Signaling ⬇️

scientific article published on March 20, 2013

Receptor tyrosine phosphatase-delta is a homophilic, neurite-promoting cell adhesion molecular for CNS neurons

scientific article published in October 1999

Receptor tyrosine phosphatases guide vertebrate motor axons during development.

scientific article published in April 2005

Regulation of retinal neurite growth by alterations in MAPK/ERK kinase (MEK) activity

scientific article published on 01 March 2000

SHP-2 mediates target-regulated axonal termination and NGF-dependent neurite growth in sympathetic neurons

scientific journal article

Stress Increases Peripheral Axon Growth and Regeneration through Glucocorticoid Receptor-Dependent Transcriptional Programs.

scientific article

Target contact regulates expression of synaptotagmin genes in spinal motor neurons in vivo

scientific article published in January 1997

Tetraspanins expressed in the embryonic chick nervous system

scientific article published in November 1999

The mTOR Substrate S6 Kinase 1 (S6K1) Is a Negative Regulator of Axon Regeneration and a Potential Drug Target for Central Nervous System Injury

scientific article published on 16 June 2017

Tissue specific expression of Yrk kinase: implications for differentiation and inflammation

scientific article published on March 2000

Transcriptional profiling of intrinsic PNS factors in the postnatal mouse.

scientific article

Ultrastructural observations on synapse elimination in neonatal rabbit skeletal muscle ⬇️

scientific article published on 01 February 1981

cJun promotes CNS axon growth

scientific article

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