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List of works by Don J. Diamond

A functional recombinant single-chain T cell receptor fragment capable of selectively targeting antigen-presenting cells.

scientific article published on 13 September 2002

A fusion protein of HCMV IE1 exon4 and IE2 exon5 stimulates potent cellular immunity in an MVA vaccine vector.

scientific article published on 5 June 2008

A novel approach to evaluate the immunogenicity of viral antigens of clinical importance in HLA transgenic murine models

scientific article published on 13 August 2008

A road less traveled paved by IDO silencing: Harnessing the antitumor activity of neutrophils

scientific article published on March 2013

A vaccine based on the rhesus cytomegalovirus UL128 complex induces broadly neutralizing antibodies in rhesus macaques.

scientific article published on 14 November 2012

Adaptive NK cell reconstitution is associated with better clinical outcomes

scholarly article by Frank Cichocki et al published 24 January 2019 in JCI insight

Adaptive Natural Killer Cell and Killer Cell Immunoglobulin-Like Receptor-Expressing T Cell Responses are Induced by Cytomegalovirus and Are Associated with Protection against Cytomegalovirus Reactivation after Allogeneic Donor Hematopoietic Cell Tr

scientific article

An HLA-restricted, p53 specific immune response from HLA transgenic p53 knockout mice ⬇️

scientific article published on January 1, 1998

An MVA vaccine overcomes tolerance to human p53 in mice and humans

scientific article published on 12 January 2007

Assessment of cellular immunity to human cytomegalovirus in recipients of allogeneic stem cell transplants.

scientific article published on July 2004

Attenuated poxvirus expressing three immunodominant CMV antigens as a vaccine strategy for CMV infection.

scientific article

Attenuated poxviruses generate clinically relevant frequencies of CMV-specific T cells.

scientific article

CD154 expression is associated with neutralizing antibody titer levels postinfluenza vaccination in stem cell transplant patients and healthy adults

scientific article

CD56dimCD57+NKG2C+ NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT.

scientific article published on 29 September 2015

CMVpp65 Vaccine Enhances the Antitumor Efficacy of Adoptively Transferred CD19-Redirected CMV-Specific T Cells.

scientific article published on 2 April 2015

CTLA-4 blockade enhances the therapeutic effect of an attenuated poxvirus vaccine targeting p53 in an established murine tumor model

scientific article published on March 2003

Carbon nanotubes enhance CpG uptake and potentiate antiglioma immunity

scientific article

Characterization of cytotoxic function of CMV-pp65-specific CD8+ T-lymphocytes identified by HLA tetramers in recipients and donors of stem-cell transplants

scientific article

Characterization of host immunity to cytomegalovirus pp150 (UL32).

scientific article

Characterization of immunologic properties of a second HLA-A2 epitope from a granule protease in CML patients and HLA-A2 transgenic mice

scientific article

Characterization of nuclear protein binding to the interferon-gamma promoter in quiescent and activated human T cells.

scientific article

Chimeric Antigen Receptors Targeting Human Cytomegalovirus

scientific article published on 13 April 2020

Clinical evaluation of safety and immunogenicity of PADRE-cytomegalovirus (CMV) and tetanus-CMV fusion peptide vaccines with or without PF03512676 adjuvant

scientific article published on 7 March 2012

Comparison of homologous and heterologous prime-boost vaccine approaches using Modified Vaccinia Ankara and soluble protein to induce neutralizing antibodies by the human cytomegalovirus pentamer complex in mice

scientific article published on 16 August 2017

Comparison of monovalent glycoprotein B with bivalent gB/pp65 (GP83) vaccine for congenital cytomegalovirus infection in a guinea pig model: Inclusion of GP83 reduces gB antibody response but both vaccine approaches provide equivalent protection aga

scientific article published on 13 June 2015

Complete regression of cutaneous metastases with systemic immune response in a patient with triple negative breast cancer receiving p53MVA vaccine with pembrolizumab.

scientific article published on 11 August 2017

Correction for Chiuppesi et al., "Multiantigenic Modified Vaccinia Virus Ankara Vaccine Vectors To Elicit Potent Humoral and Cellular Immune Responses against Human Cytomegalovirus in Mice"

scientific article published on 13 November 2019

Cross-reactive CTL recognizing two HLA-A*02-restricted epitopes within the BK virus and JC virus VP1 polypeptides are frequent in immunocompetent individuals

scientific article published on 5 April 2006

Cross-reactivity of T lymphocytes recognizing a human cytotoxic T-lymphocyte epitope within BK and JC virus VP1 polypeptides.

scientific article

Cytomegalovirus immune reconstitution occurs in recipients of allogeneic hematopoietic cell transplants irrespective of detectable cytomegalovirus infection.

scientific article published in November 2005

Cytomegalovirus-vectored vaccines for HIV and other pathogens

scientific article published on 01 March 2020

DNA and low titer, helper-free, recombinant AAV prime-boost vaccination for cytomegalovirus induces an immune response to CMV-pp65 and CMV-IE1 in transgenic HLA A*0201 mice

scientific article

DNA vaccine prime followed by boost with live attenuated virus significantly improves antigen-specific T cell responses against human cytomegalovirus.

scientific article published on 25 July 2013

Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice

scientific article published on 06 September 2019

Detection and preliminary characterization of CD8+T lymphocytes specific for Wilms' tumor antigen in patients with non-Hodgkin lymphoma.

scientific article

Developing Effective Salmonella-based Approaches to Treat Pancreatic Cancer

scientific article published on January 2016

Development of a Multi-Antigenic SARS-CoV-2 Vaccine Using a Synthetic Poxvirus Platform

scientific article published on 17 July 2020

Development of a Synthetic Poxvirus-Based SARS-CoV-2 Vaccine

scientific article published on 02 July 2020

Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform

scientific article published on 30 November 2020

Development of a novel, guinea pig-specific IFN-γ ELISPOT assay and characterization of guinea pig cytomegalovirus GP83-specific cellular immune responses following immunization with a modified vaccinia virus Ankara (MVA)-vectored GP83 vaccine

scientific article

Effective cancer vaccine platform based on attenuated salmonella and a type III secretion system

scientific article

Effects of rat growth hormone (rGH)-releasing factor and somatostatin on the release and synthesis of rGH in dispersed pituitary cells.

scientific article

Enhancement of cancer vaccine therapy by systemic delivery of a tumor-targeting Salmonella-based STAT3 shRNA suppresses the growth of established melanoma tumors

scientific article published on 28 April 2011

Evaluation of innate and adaptive immunity contributing to the antitumor effects of PD1 blockade in an orthotopic murine model of pancreatic cancer

scientific article published on 16 March 2016

Evaluation of recombinant modified vaccinia Ankara virus-based rhesus cytomegalovirus vaccines in rhesus macaques

scientific article published on 15 January 2008

Evaluation of safety and efficacy of p53MVA vaccine combined with pembrolizumab in patients with advanced solid cancers

scientific article published on 09 August 2018

Ex vivo detection of CD8 T cells specific for H-Y minor histocompatibility antigens in allogeneic hematopoietic stem cell transplant recipients

scientific article

Exciting Times for Cytomegalovirus (CMV) Vaccine Development: Navigating the Pathways toward the Goal of Protecting Infants against Congenital CMV Infection

scientific article published on 14 September 2020

Exploiting 2A Peptides to Elicit Potent Neutralizing Antibodies by a Multi-Subunit Herpesvirus Glycoprotein Complex

scientific article published on 6 October 2017

Functional characterization of BK virus-specific CD4+ T cells with cytotoxic potential in seropositive adults

scientific article published in September 2007

Functional comparison of T cells recognizing cytomegalovirus pp65 and intermediate-early antigen polypeptides in hematopoietic stem-cell transplant and solid organ transplant recipients

scientific article published on 11 October 2006

Heterologous prime/boost immunization with p53-based vaccines combined with toll-like receptor stimulation enhances tumor regression.

scientific article

Human cytomegalovirus proteins pp65 and immediate early protein 1 are common targets for CD8+ T cell responses in children with congenital or postnatal human cytomegalovirus infection

scientific article published on February 2004

Human cytomegalovirus vaccine based on the envelope gH/gL pentamer complex

scientific article published on 20 November 2014

Human cytomegalovirus vaccine: time to look for alternative options.

scientific article

Human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy maintain activated CD8+ T cell subsets as a strong adaptive immune response to cytomegalovirus.

scientific article published on 10 July 2001

Identification of a Continuous Neutralizing Epitope within UL128 of Human Cytomegalovirus

scientific article published on 11 January 2017

Immunization with Th-CTL Fusion Peptide and Cytosine-Phosphate-Guanine DNA in Transgenic HLA-A2 Mice Induces Recognition of HIV-Infected T Cells and Clears Vaccinia Virus Challenge ⬇️

scientific article published on October 15, 2003

Impact of donor CMV status on viral infection and reconstitution of multifunction CMV-specific T cells in CMV-positive transplant recipients

scientific article published on 15 April 2009

In vitro expansion of polyclonal T-cell subsets for adoptive immunotherapy by recombinant modified vaccinia Ankara

scientific article published on April 2006

Increased programmed death-1 molecule expression in cytomegalovirus disease and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation

scientific article published on July 2009

Induction of CTL response by a minimal epitope vaccine in HLA A*0201/DR1 transgenic mice: dependence on HLA class II restricted T(H) response.

scientific article published on August 2000

Infrequent occurrence of natural mutations in the pp65(495-503) epitope sequence presented by the HLA A*0201 allele among human cytomegalovirus isolates

scientific article

Intergenic region 3 of modified vaccinia ankara is a functional site for insert gene expression and allows for potent antigen-specific immune responses

scientific article

Intracerebral CpG immunotherapy with carbon nanotubes abrogates growth of subcutaneous melanomas in mice

scientific article

La Rosa C et al (J Infect Dis 2012; 205:1294–304).

scientific article published in September 2013

Lack of association of cytomegalovirus with human brain tumors.

scientific article

Longitudinal assessment of cytomegalovirus (CMV)-specific immune responses in liver transplant recipients at high risk for late CMV disease

scientific article published on 22 January 2007

MVA vaccine encoding CMV antigens safely induces durable expansion of CMV-specific T cells in healthy adults

scientific article

MVA-Vectored Pentameric Complex (PC) and gB Vaccines Improve Pregnancy Outcome after Guinea Pig CMV Challenge, but Only gB Vaccine Reduces Vertical Transmission

scientific article published on 14 November 2019

Mamu-A01/K(b) transgenic and MHC Class I knockout mice as a tool for HIV vaccine development

scientific article published on 27 February 2009

Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission

scientific article

Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids

scientific article published on 25 March 2020

Modified H5 promoter improves stability of insert genes while maintaining immunogenicity during extended passage of genetically engineered MVA vaccines

scientific article

Modified vaccinia Ankara expressing survivin combined with gemcitabine generates specific antitumor effects in a murine pancreatic carcinoma model.

scientific article

Multiantigenic Modified Vaccinia Virus Ankara Vaccine Vectors To Elicit Potent Humoral and Cellular Immune Reponses against Human Cytomegalovirus in Mice

scholarly article by Flavia Chiuppesi et al published 1 October 2018 in Journal of Virology

Neutralization of Human Cytomegalovirus Entry into Fibroblasts and Epithelial Cells

scientific article published on 31 October 2017

Novel conjugates of epitope fusion peptides with CpG-ODN display enhanced immunogenicity and HIV recognition.

scientific article published in May 2005

Oblimersen and alpha-interferon in metastatic renal cancer: a phase II study of the California Cancer Consortium.

scientific article published on 17 May 2007

Open reading frames carried on UL/b' are implicated in shedding and horizontal transmission of rhesus cytomegalovirus in rhesus monkeys.

scientific article

Overcoming immunosuppression to enhance a p53MVA vaccine.

scientific article

Patterns of acute rhesus cytomegalovirus (RhCMV) infection predict long-term RhCMV infection.

scientific article

Plasma IL-10 Levels to Guide Antiviral Prophylaxis Prevention of Late-Onset Cytomegalovirus Disease, in High Risk Solid Kidney and Liver Transplant Recipients

scientific article

Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission

scientific article published on 15 March 2017

Population coverage by HLA class-I restricted cytotoxic T-lymphocyte epitopes.

scientific article published in January 2001

Poxvirus Vectored Cytomegalovirus Vaccine to Prevent Cytomegalovirus Viremia in Transplant Recipients: A Phase 2, Randomized Clinical Trial

scientific article published on 11 February 2020

Preclinical development of an adjuvant-free peptide vaccine with activity against CMV pp65 in HLA transgenic mice.

scientific article published on 12 July 2002

Predictors of reported influenza vaccination in HIV-infected women in the United States, 2006-2007 and 2007-2008 seasons

scientific article

Predominant type 1 CMV-specific memory T-helper response in humans: evidence for gender differences in cytokine secretion

scientific article published in May 2004

Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys.

scientific article

Primary response against cytomegalovirus during antiviral prophylaxis with valganciclovir, in solid organ transplant recipients

scientific article

Programmed death-1 expression in liver transplant recipients as a prognostic indicator of cytomegalovirus disease.

scientific article

Programmed death-1 receptor and interleukin-10 in liver transplant recipients at high risk for late cytomegalovirus disease

scientific article

Rapid Acquisition of Cytomegalovirus-Specific T Cells with a Differentiated Phenotype, in Nonviremic Hematopoietic Stem Transplant Recipients Vaccinated with CMVPepVax

scientific article published on 16 December 2018

Real-time assessment of relapse risk based on the WT1 marker in acute leukemia and myelodysplastic syndrome patients after hematopoietic cell transplantation

scientific article

Recombinant modified vaccinia virus Ankara expressing a soluble form of glycoprotein B causes durable immunity and neutralizing antibodies against multiple strains of human cytomegalovirus

scientific article published on April 2004

Recombinant modified vaccinia virus ankara (MVA) expressing wild-type human p53 induces specific antitumor CTL expansion.

scientific article published on 15 August 2011

Reduced frequencies of polyfunctional CMV-specific T cell responses in infants with congenital CMV infection

scientific article

Reduced type 1 and type 2 cytokines in antiviral memory T helper function among women coinfected with HIV and HCV.

scientific article

Regulation of growth hormone messenger RNA synthesis by dexamethasone and triiodothyronine. Transcriptional rate and mRNA stability changes in pituitary tumor cells

scientific article published on 01 January 1985

Relative dominance of HLA-B*07 restricted CD8+ T-lymphocyte immune responses to human cytomegalovirus pp65 in persons sharing HLA-A*02 and HLA-B*07 alleles

scientific article published in April 2003

Relevance of peptide avidity to the T cell receptor for cytomegalovirus-specific ex vivo CD8 T cell cytotoxicity

scientific article published on 9 September 2003

Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Coupled with Enzymatic Depletion of Tumor Hyaluronan Induces Complete Regression of Aggressive Pancreatic Tumors

scientific article

Salmonella-mediated therapy targeting indoleamine 2, 3-dioxygenase 1 (IDO) activates innate immunity and mitigates colorectal cancer growth

scientific article published on 01 March 2019

Simultaneous reconstitution of multiple cytomegalovirus-specific CD8+ cell populations with divergent functionality in hematopoietic stem-cell transplant recipients.

scientific article published on 9 February 2005

Site-directed mutation in a conserved kinase domain of human cytomegalovirus-pp65 with preservation of cytotoxic T lymphocyte targeting.

scientific article

Status of Cytomegalovirus Prevention and Treatment in 2000.

scientific article

Survivin the battle against immunosuppression.

scientific article published on March 2012

Systemic delivery of Salmonella typhimurium transformed with IDO shRNA enhances intratumoral vector colonization and suppresses tumor growth

scientific article

TLR9 signaling in the tumor microenvironment initiates cancer recurrence after radiotherapy

scientific article published on 23 October 2013

The effect of single and combined activating killer immunoglobulin-like receptor genotypes on cytomegalovirus infection and immunity after hematopoietic cell transplantation

scientific article published on March 2009

The immune response to human CMV

scientific article published on March 2012

The susceptibility of primary cultured rhesus macaque kidney epithelial cells to rhesus cytomegalovirus strains.

scientific article published on 14 March 2016

The use of transgenic mice to generate high affinity p53 specific cytolytic T cells.

scientific article published on May 1997

Tumor growth control with IDO-silencing Salmonella--reply

scientific article published on 5 July 2013

Two distinct pathways of immuno-modulation improve potency of p53 immunization in rejecting established tumors.

scientific article

Unusual organization and diversity of T-cell receptor alpha-chain genes.

scientific article published in August 1985

Vaccine properties of a novel marker gene-free recombinant modified vaccinia Ankara expressing immunodominant CMV antigens pp65 and IE1.

scientific article published on 6 October 2006

Vaccine-Derived Neutralizing Antibodies to the Human Cytomegalovirus gH/gL Pentamer Potently Block Primary Cytotrophoblast Infection

scientific article

Vaccine-induced control of viral shedding following rhesus cytomegalovirus challenge in rhesus macaques.

scientific article

Viraemia, immunogenicity, and survival outcomes of cytomegalovirus chimeric epitope vaccine supplemented with PF03512676 (CMVPepVax) in allogeneic haemopoietic stem-cell transplantation: randomised phase 1b trial

scientific article

p53-reactive T cells are associated with clinical benefit in patients with platinum-resistant epithelial ovarian cancer after treatment with a p53 vaccine and gemcitabine chemotherapy

scientific article published on 4 January 2018

p53MVA therapy in patients with refractory gastrointestinal malignancies elevates p53-specific CD8+ T-cell responses

scientific article

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