List of works - Sonia Levi

A human mitochondrial ferritin encoded by an intronless gene

scientific journal article

A mutational analysis of the epitopes of recombinant human H-ferritin

scientific article published on 01 June 1990

A new mutation (G51C) in the iron-responsive element (IRE) of l-ferritin associated with hyperferritinaemia-cataract syndrome decreases the binding affinity of the mutated IRE for iron-regulatory proteins

scientific article published on 01 March 2000

A novel deletion of the l-ferritin iron-responsive element responsible for severe hereditary hyperferritinaemia-cataract syndrome

scientific article published on 01 March 2002

A novel neuroferritinopathy mouse model (FTL 498InsTC) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits.

scientific article

Analysis of ferritin genes in Parkinson disease

article

Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin

scientific article published on 13 November 2003

C29G in the iron-responsive element of L-ferritin: a new mutation associated with hyperferritinemia-cataract

scientific article published in July 2004

Characteristics of ferritins in human milk secretions: Similarities to serum and tissue isoferritins

scientific article published on 01 December 1986

Characterization of human ferritin H chain synthetized in Escherichia coli.

scientific article

Characterization of human mitochondrial ferritin promoter: identification of transcription factors and evidences of epigenetic control

scientific article

Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder

scientific article published on 05 July 2006

Clinical, biochemical and molecular findings in a series of families with hereditary hyperferritinaemia-cataract syndrome

scientific article published on 01 November 2001

Coenzyme A corrects pathological defects in human neurons of PANK2-associated neurodegeneration

scientific article published on 11 August 2016

Crystal structure and biochemical properties of the human mitochondrial ferritin and its mutant Ser144Ala

scientific article

Crystallographic data for horse heart ferritin

scholarly article by Martino Bolognesi published in January 1984

Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage

scientific article published on 20 February 2010

Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis

scientific article published on 30 January 2007

Development of an immunoassay for all human isoferritins, and its application to serum ferritin evaluation

scientific article published on October 1989

Early embryonic lethality of H ferritin gene deletion in mice

scientific article published in February 2000

Effects of mitochondrial ferritin overexpression in normal and sideroblastic erythroid progenitors.

scientific article published on 10 April 2013

Ferroportin gene silencing induces iron retention and enhances ferritin synthesis in human macrophages

article

Flow cytometry evaluation of erythroid dysplasia in patients with myelodysplastic syndrome

scientific article published in April 2006

Functional and Immunological Analysis of Recombinant Mouse H- and L-Ferritins from Escherichia coli

scientific article published on 01 June 2000

Functional roles of the ferritin receptors of human liver, hepatoma, lymphoid and erythroid cells

scientific article published on August 1992

Genetic hyperferritinaemia and reticuloendothelial iron overload associated with a three base pair deletion in the coding region of the ferroportin gene (SLC11A3).

scientific article published in November 2002

H and L ferritins in myocardium in iron overload

scientific article published in November 1991

H ferritin silencing induces protein misfolding in K562 cells: A Raman analysis

scientific article published on 7 October 2015

Human L-ferritin deficiency is characterized by idiopathic generalized seizures and atypical restless leg syndrome.

scientific article published on 12 August 2013

Human ferritin H-chains can be obtained in non-assembled stable forms which have ferroxidase activity

scientific article published on 01 December 1993

Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism

scientific article published on 12 April 2002

Identification of the ferroxidase centre in ferritin

scientific article published on 01 August 1989

Immunochemical characterization of human liver and heart ferritins with monoclonal antibodies.

scientific article

Influence of site-directed modifications on the formation of iron cores in ferritin

scientific article published on 01 October 1991

Iron availability is increased in individual human ovarian follicles in close proximity to an endometrioma compared with distal ones

scientific article published on 15 January 2014

Iron detoxifying activity of ferritin

scientific article published on 01 December 1990

Iron homeostasis in peripheral nervous system, still a black box?

scientific article

Microelectronic DNA chip for hereditary hyperferritinemia cataract syndrome, a model for large-scale analysis of disorders of iron metabolism.

scientific article published in February 2006

Mitochondrial ferritin expression in adult mouse tissues

scientific article published on 11 July 2007

Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia

scientific article

Mitochondrial ferritin limits oxidative damage regulating mitochondrial iron availability: hypothesis for a protective role in Friedreich ataxia

scientific article

Mitochondrial ferritin.

scientific article published on October 2004

Mitochondrial iron and energetic dysfunction distinguish fibroblasts and induced neurons from pantothenate kinase-associated neurodegeneration patients

scientific article published on 30 March 2015

Multiple Pathways for Mineral Core Formation in Mammalian Apoferritin. The Role of Hydrogen Peroxide†

scientific article published on 01 March 2003

Multiple mechanisms of iron-induced ferritin synthesis in HeLa cells

scientific article published in 1985

Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation

scientific article

Neurodegeneration with brain iron accumulation: update on pathogenic mechanisms

scientific article published in 2014

Neuroferritinopathy: From ferritin structure modification to pathogenetic mechanism

scientific article

Neuronal Ablation of CoA Synthase Causes Motor Deficits, Iron Dyshomeostasis, and Mitochondrial Dysfunctions in a CoPAN Mouse Model

scientific article published on 19 December 2020

Over-expression of mitochondrial ferritin affects the JAK2/STAT5 pathway in K562 cells and causes mitochondrial iron accumulation

scientific article

Overexpression of the hereditary hemochromatosis protein, HFE, in HeLa cells induces an iron-deficient phenotype

scientific article published on 01 October 1999

Overexpression of wild type and mutated human ferritin H-chain in HeLa cells: in vivo role of ferritin ferroxidase activity.

scientific article

Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy

scientific article published on 23 September 2009

Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model

scientific journal article

RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload

scientific article published on 27 December 2006

Recombinant human hepcidin expressed in Escherichia coli isolates as an iron containing protein

scientific article published on 01 September 2005

Reconstitution of manganese oxide cores in horse spleen and recombinant ferritins.

scientific article published in April 1995

Regional and cellular distribution of mitochondrial ferritin in the mouse brain

scientific article published on 01 November 2010

Regulation of ferritin synthesis in malignant and non-malignant lymphoid cells

scientific article published on 01 September 1986

Relationship between TNF-alpha and iron metabolism in differentiating human monocytic THP-1 cells.

scientific article

Role of intracellular labile iron, ferritin, and antioxidant defence in resistance of chronically adapted Jurkat T cells to hydrogen peroxide

scientific article

Role of iron and ferritin in TNFalpha-induced apoptosis in HeLa cells

scientific article published in February 2003

Sequence variations in mitochondrial ferritin: distribution in healthy controls and different types of patients.

scientific article

Serum ferritin in type I diabetes

Skin fibroblasts from pantothenate kinase-associated neurodegeneration patients show altered cellular oxidative status and have defective iron-handling properties.

scientific article

Structure, function, and evolution of ferritins.

scientific article

Study of FTMT and ABCA4 genes in a patient affected by age-related macular degeneration: identification and analysis of new mutations.

scientific article published on 9 January 2012

The Role of the L-Chain in Ferritin Iron Incorporation

scientific article published on 01 May 1994

The dentate nucleus in Friedreich's ataxia: the role of iron-responsive proteins

scientific article

The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast

scientific article published on 28 July 2004

The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload.

scientific article

The pathogenesis of cardiomyopathy in Friedreich ataxia.

scientific article

The relevance of mitochondrial DNA variants fluctuation during reprogramming and neuronal differentiation of human iPSCs

scientific article published on 29 July 2021

Unexplained isolated hyperferritinemia without iron overload

scientific article

List of works by Sonia Levi

A human mitochondrial ferritin encoded by an intronless gene

A mutational analysis of the epitopes of recombinant human H-ferritin

A new mutation (G51C) in the iron-responsive element (IRE) of l-ferritin associated with hyperferritinaemia-cataract syndrome decreases the binding affinity of the mutated IRE for iron-regulatory proteins

A novel deletion of the l-ferritin iron-responsive element responsible for severe hereditary hyperferritinaemia-cataract syndrome

A novel neuroferritinopathy mouse model (FTL 498InsTC) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits.

Analysis of ferritin genes in Parkinson disease

Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin

C29G in the iron-responsive element of L-ferritin: a new mutation associated with hyperferritinemia-cataract

Characteristics of ferritins in human milk secretions: Similarities to serum and tissue isoferritins

Characterization of human ferritin H chain synthetized in Escherichia coli.

Characterization of human mitochondrial ferritin promoter: identification of transcription factors and evidences of epigenetic control

Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder

Clinical, biochemical and molecular findings in a series of families with hereditary hyperferritinaemia-cataract syndrome

Coenzyme A corrects pathological defects in human neurons of PANK2-associated neurodegeneration

Crystal structure and biochemical properties of the human mitochondrial ferritin and its mutant Ser144Ala

Crystallographic data for horse heart ferritin

Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage

Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis

Development of an immunoassay for all human isoferritins, and its application to serum ferritin evaluation

Early embryonic lethality of H ferritin gene deletion in mice

Effects of mitochondrial ferritin overexpression in normal and sideroblastic erythroid progenitors.

Ferroportin gene silencing induces iron retention and enhances ferritin synthesis in human macrophages

Flow cytometry evaluation of erythroid dysplasia in patients with myelodysplastic syndrome

Functional and Immunological Analysis of Recombinant Mouse H- and L-Ferritins from Escherichia coli

Functional roles of the ferritin receptors of human liver, hepatoma, lymphoid and erythroid cells

Genetic hyperferritinaemia and reticuloendothelial iron overload associated with a three base pair deletion in the coding region of the ferroportin gene (SLC11A3).

H and L ferritins in myocardium in iron overload

H ferritin silencing induces protein misfolding in K562 cells: A Raman analysis

Human L-ferritin deficiency is characterized by idiopathic generalized seizures and atypical restless leg syndrome.

Human ferritin H-chains can be obtained in non-assembled stable forms which have ferroxidase activity

Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism

Identification of the ferroxidase centre in ferritin

Immunochemical characterization of human liver and heart ferritins with monoclonal antibodies.

Influence of site-directed modifications on the formation of iron cores in ferritin

Iron availability is increased in individual human ovarian follicles in close proximity to an endometrioma compared with distal ones

Iron detoxifying activity of ferritin

Iron homeostasis in peripheral nervous system, still a black box?

Microelectronic DNA chip for hereditary hyperferritinemia cataract syndrome, a model for large-scale analysis of disorders of iron metabolism.

Mitochondrial ferritin expression in adult mouse tissues

Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia

Mitochondrial ferritin limits oxidative damage regulating mitochondrial iron availability: hypothesis for a protective role in Friedreich ataxia

Mitochondrial ferritin.

Mitochondrial iron and energetic dysfunction distinguish fibroblasts and induced neurons from pantothenate kinase-associated neurodegeneration patients

Multiple Pathways for Mineral Core Formation in Mammalian Apoferritin. The Role of Hydrogen Peroxide†

Multiple mechanisms of iron-induced ferritin synthesis in HeLa cells

Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation

Neurodegeneration with brain iron accumulation: update on pathogenic mechanisms

Neuroferritinopathy: From ferritin structure modification to pathogenetic mechanism

Neuronal Ablation of CoA Synthase Causes Motor Deficits, Iron Dyshomeostasis, and Mitochondrial Dysfunctions in a CoPAN Mouse Model

Over-expression of mitochondrial ferritin affects the JAK2/STAT5 pathway in K562 cells and causes mitochondrial iron accumulation

Overexpression of the hereditary hemochromatosis protein, HFE, in HeLa cells induces an iron-deficient phenotype

Overexpression of wild type and mutated human ferritin H-chain in HeLa cells: in vivo role of ferritin ferroxidase activity.

Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy

Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model

RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload

Recombinant human hepcidin expressed in Escherichia coli isolates as an iron containing protein

Reconstitution of manganese oxide cores in horse spleen and recombinant ferritins.

Regional and cellular distribution of mitochondrial ferritin in the mouse brain

Regulation of ferritin synthesis in malignant and non-malignant lymphoid cells

Relationship between TNF-alpha and iron metabolism in differentiating human monocytic THP-1 cells.

Role of intracellular labile iron, ferritin, and antioxidant defence in resistance of chronically adapted Jurkat T cells to hydrogen peroxide

Role of iron and ferritin in TNFalpha-induced apoptosis in HeLa cells

Sequence variations in mitochondrial ferritin: distribution in healthy controls and different types of patients.

Serum ferritin in type I diabetes

Skin fibroblasts from pantothenate kinase-associated neurodegeneration patients show altered cellular oxidative status and have defective iron-handling properties.

Structure, function, and evolution of ferritins.

Study of FTMT and ABCA4 genes in a patient affected by age-related macular degeneration: identification and analysis of new mutations.

The Role of the L-Chain in Ferritin Iron Incorporation

The dentate nucleus in Friedreich's ataxia: the role of iron-responsive proteins

The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast

The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload.

The pathogenesis of cardiomyopathy in Friedreich ataxia.

The relevance of mitochondrial DNA variants fluctuation during reprogramming and neuronal differentiation of human iPSCs

Unexplained isolated hyperferritinemia without iron overload