List of works - Thomas Flatt

A Bit of Sex Stabilizes Host–Parasite Dynamics

article

A New Definition of Aging? ⬇️

scientific article published on August 23, 2012

A clinal polymorphism in the insulin signaling transcription factor foxo contributes to life-history adaptation in Drosophila

scientific article published on 29 May 2019

A role for genetic accommodation in evolution?

scientific article

Adaptation of Drosophila to a novel laboratory environment reveals temporally heterogeneous trajectories of selected alleles

scientific article

Adaptation to developmental diet influences the response to selection on age at reproduction in the fruit fly

scientific article published on 27 February 2019

Adaptation to fluctuating environments in a selection experiment with Drosophila melanogaster

scientific article published on 18 April 2017

Ageing: Diet and longevity in the balance

scientific article published in December 2009

Allelic polymorphism at foxo contributes to local adaptation in Drosophila melanogaster

article published in 2018

Allelic polymorphism at foxo contributes to local adaptation in Drosophila melanogaster

scientific article published on 18 May 2021

Altering the Temporal Regulation of One Transcription Factor Drives Evolutionary Trade-Offs between Head Sensory Organs

scientific article published on 22 August 2019

Altering the Temporal Regulation of One Transcription Factor Drives Sensory Trade-Offs

scientific article published in 2018

Altering the temporal regulation of one transcription factor drives sensory trade-offs

Aminergic Signaling Controls Ovarian Dormancy in Drosophila

scientific article

An inversion supergene in Drosophila underpins latitudinal clines in survival traits

scientific article published on 28 June 2018

Assessing natural variation in genes affecting Drosophila lifespan

scientific article published in March 2004

Broad geographic sampling reveals predictable and pervasive seasonal adaptation in Drosophila

Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila

scientific article published in 2021

Comparing thyroid and insect hormone signaling ⬇️

scientific article published on September 7, 2006

Counting calories in Drosophila diet restriction

scientific article

Distinct genomic signals of lifespan and life history evolution in response to postponed reproduction and larval diet in Drosophila

scientific article published on 02 October 2019

Drosophila germ-line modulation of insulin signaling and lifespan

scholarly article

Ecdysone triggered PGRP-LC expression controls Drosophila innate immunity

scientific article published on 7 May 2013

Endocrine uncoupling of the trade-off between reproduction and somatic maintenance in eusocial insects

scientific article

Evolution in group-structured populations can resolve the tragedy of the commons

scientific article published in June 2006

Evolution of longevity improves immunity in

scientific article published on 12 November 2018

Evolutionary genomics can improve prediction of species' responses to climate change

scientific article published on 14 January 2020

Gene Coexpression Network Reveals Highly Conserved, Well-Regulated Anti-Ageing Mechanisms in Old Ant Queens

scientific article published on 01 June 2021

Genome-wide patterns of latitudinal differentiation among populations of Drosophila melanogaster from North America

scientific article

Genomic Evidence for Adaptive Inversion Clines in Drosophila melanogaster.

scientific article

Genomic analysis of European Drosophila melanogaster populations reveals longitudinal structure, continent-wide selection, and previously unknown DNA viruses

scientific article published on 15 May 2020

Genomic analysis of European Drosophila populations reveals longitudinal structure and continent-wide selection

scientific article published on 3 May 2018

Genomics of clinal variation in Drosophila: disentangling the interactions of selection and demography

scientific article published in March 2016

Hormonal pleiotropy and the juvenile hormone regulation of Drosophila development and life history

scientific article

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster

scientific article published on August 2008

Host range and specificity of the Drosophila C virus

scientific article

How flies turn food into progeny

scientific article published on 01 October 2019

Inference of chromosomal inversion dynamics from Pool-Seq data in natural and laboratory populations of Drosophila melanogaster

scientific article

Integrating evolutionary and molecular genetics of aging.

scientific article

Juvenile hormone as a regulator of the trade-off between reproduction and life span in Drosophila melanogaster

scientific article published in August 2007

Life-History Evolution and the Genetics of Fitness Components in Drosophila melanogaster

scientific article published on 01 January 2020

Life-history evolution and the polyphenic regulation of somatic maintenance and survival

scientific article

Living Long and Well: Prospects for a Personalized Approach to the Medicine of Ageing

scientific article published on 17 December 2015

Mark-Recapture Estimates of Survival in Populations of the Asp Viper, Vipera aspis aspis

article

Neuronal inputs and outputs of aging and longevity

scientific article published on 6 May 2013

Parallel effects of the inversion In(3R)Payne on body size across the North American and Australian clines in Drosophila melanogaster

scientific article published on 16 February 2016

Paying the costs of reproduction.

scientific article published on 28 July 2015

Physiology. Still pondering an age-old question

scientific article published in November 2007

Plasticity of lifespan: a reaction norm perspective

scientific article

Pleiotropic effects of methoprene-tolerant (Met), a gene involved in juvenile hormone metabolism, on life history traits in Drosophila melanogaster

scientific article published in October 2004

Reproduction, fat metabolism, and life span: what is the connection?

scientific article published on January 2013

Reproductive and post-reproductive life history of wild-caught Drosophila melanogaster under laboratory conditions.

scientific article

Similarities and differences in altitudinal versus latitudinal variation for morphological traits in Drosophila melanogaster

scientific article published on 4 March 2014

Size and shape: the developmental regulation of static allometry in insects.

scientific article published on June 2007

Spatially varying selection shapes life history clines among populations of Drosophila melanogaster from sub-Saharan Africa

scientific article published on 13 March 2015

Stabilizing factors interact in promoting host–parasite coexistence

scientific article published on 01 May 2004

Steroid hormone regulation of C. elegans and Drosophila aging and life history

scientific article published on 17 September 2010

Survival costs of reproduction in Drosophila ⬇️

scientific article published on October 21, 2010

The adaptive significance of chromosomal inversion polymorphisms in Drosophila melanogaster

scientific article published in 2018

The adaptive significance of chromosomal inversion polymorphisms in Drosophila melanogaster

The diversity of population responses to environmental change.

scientific article

The evolutionary genetics of canalization

scientific article

The genomic and physiological basis of life history variation in a butterfly metapopulation

scientific article published on May 2011

The interplay between immunity and aging in Drosophila.

scientific article published on 7 February 2018

The role of the nervous system in aging and longevity

scientific article published on 27 June 2013

Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes

scientific article

Ubiquitous overexpression of the DNA repair factor dPrp19 reduces DNA damage and extends Drosophila life span

scientific article

Variation in thermal performance and reaction norms among populations of Drosophila melanogaster

scientific article published on 26 August 2013

What is Aging?

scientific article published in 2012

What is metamorphosis?

scientific article published on 6 June 2006

Winter weather affects asp viper Vipera aspis population dynamics through susceptible juveniles

article

Winter weather affects asp viper Vipera aspis population dynamics through susceptible juveniles

scientific article published in 2005

dSir2 and Dmp53 interact to mediate aspects of CR-dependent lifespan extension in D. melanogaster

scientific article published on January 2009

List of works by Thomas Flatt

A Bit of Sex Stabilizes Host–Parasite Dynamics

A New Definition of Aging? ⬇️

A clinal polymorphism in the insulin signaling transcription factor foxo contributes to life-history adaptation in Drosophila

A clinal polymorphism in the insulin signaling transcription factor foxo contributes to life-history adaptation in Drosophila

A role for genetic accommodation in evolution?

Adaptation of Drosophila to a novel laboratory environment reveals temporally heterogeneous trajectories of selected alleles

Adaptation to developmental diet influences the response to selection on age at reproduction in the fruit fly

Adaptation to fluctuating environments in a selection experiment with Drosophila melanogaster

Ageing: Diet and longevity in the balance

Allelic polymorphism at foxo contributes to local adaptation in Drosophila melanogaster

Allelic polymorphism at foxo contributes to local adaptation in Drosophila melanogaster

Altering the Temporal Regulation of One Transcription Factor Drives Evolutionary Trade-Offs between Head Sensory Organs

Altering the Temporal Regulation of One Transcription Factor Drives Sensory Trade-Offs

Altering the temporal regulation of one transcription factor drives sensory trade-offs

Aminergic Signaling Controls Ovarian Dormancy in Drosophila

An inversion supergene in Drosophila underpins latitudinal clines in survival traits

Assessing natural variation in genes affecting Drosophila lifespan

Broad geographic sampling reveals predictable and pervasive seasonal adaptation in Drosophila

Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila

Comparing thyroid and insect hormone signaling ⬇️

Counting calories in Drosophila diet restriction

Distinct genomic signals of lifespan and life history evolution in response to postponed reproduction and larval diet in Drosophila

Drosophila germ-line modulation of insulin signaling and lifespan

Ecdysone triggered PGRP-LC expression controls Drosophila innate immunity

Endocrine uncoupling of the trade-off between reproduction and somatic maintenance in eusocial insects

Evolution in group-structured populations can resolve the tragedy of the commons

Evolution of longevity improves immunity in

Evolutionary genomics can improve prediction of species' responses to climate change

Gene Coexpression Network Reveals Highly Conserved, Well-Regulated Anti-Ageing Mechanisms in Old Ant Queens

Genome-wide patterns of latitudinal differentiation among populations of Drosophila melanogaster from North America

Genomic Evidence for Adaptive Inversion Clines in Drosophila melanogaster.

Genomic analysis of European Drosophila melanogaster populations reveals longitudinal structure, continent-wide selection, and previously unknown DNA viruses

Genomic analysis of European Drosophila populations reveals longitudinal structure and continent-wide selection

Genomics of clinal variation in Drosophila: disentangling the interactions of selection and demography

Hormonal pleiotropy and the juvenile hormone regulation of Drosophila development and life history

Hormonal regulation of the humoral innate immune response in Drosophila melanogaster

Host range and specificity of the Drosophila C virus

How flies turn food into progeny

Inference of chromosomal inversion dynamics from Pool-Seq data in natural and laboratory populations of Drosophila melanogaster

Integrating evolutionary and molecular genetics of aging.

Juvenile hormone as a regulator of the trade-off between reproduction and life span in Drosophila melanogaster

Life-History Evolution and the Genetics of Fitness Components in Drosophila melanogaster

Life-history evolution and the polyphenic regulation of somatic maintenance and survival

Living Long and Well: Prospects for a Personalized Approach to the Medicine of Ageing

Mark-Recapture Estimates of Survival in Populations of the Asp Viper, Vipera aspis aspis

Neuronal inputs and outputs of aging and longevity

Parallel effects of the inversion In(3R)Payne on body size across the North American and Australian clines in Drosophila melanogaster

Paying the costs of reproduction.

Physiology. Still pondering an age-old question

Plasticity of lifespan: a reaction norm perspective

Pleiotropic effects of methoprene-tolerant (Met), a gene involved in juvenile hormone metabolism, on life history traits in Drosophila melanogaster

Reproduction, fat metabolism, and life span: what is the connection?

Reproductive and post-reproductive life history of wild-caught Drosophila melanogaster under laboratory conditions.

Similarities and differences in altitudinal versus latitudinal variation for morphological traits in Drosophila melanogaster

Size and shape: the developmental regulation of static allometry in insects.

Spatially varying selection shapes life history clines among populations of Drosophila melanogaster from sub-Saharan Africa

Stabilizing factors interact in promoting host–parasite coexistence

Steroid hormone regulation of C. elegans and Drosophila aging and life history

Survival costs of reproduction in Drosophila ⬇️

The adaptive significance of chromosomal inversion polymorphisms in Drosophila melanogaster

The adaptive significance of chromosomal inversion polymorphisms in Drosophila melanogaster

The diversity of population responses to environmental change.

The evolutionary genetics of canalization

The genomic and physiological basis of life history variation in a butterfly metapopulation

The interplay between immunity and aging in Drosophila.

The role of the nervous system in aging and longevity

Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes

Ubiquitous overexpression of the DNA repair factor dPrp19 reduces DNA damage and extends Drosophila life span

Variation in thermal performance and reaction norms among populations of Drosophila melanogaster

What is Aging?

What is metamorphosis?

Winter weather affects asp viper Vipera aspis population dynamics through susceptible juveniles

Winter weather affects asp viper Vipera aspis population dynamics through susceptible juveniles

dSir2 and Dmp53 interact to mediate aspects of CR-dependent lifespan extension in D. melanogaster