List of works - Gareth Leng

"Eating addiction", rather than "food addiction", better captures addictive-like eating behavior

scientific article

60 YEARS OF NEUROENDOCRINOLOGY: The posterior pituitary, from Geoffrey Harris to our present understanding

scientific article

A Direct Neurokinin B Projection from the Arcuate Nucleus Regulates Magnocellular Vasopressin Cells of the Supraoptic Nucleus

scientific article

A population model of vasopressin release

Actions of neuropeptide Y and growth hormone secretagogues in the arcuate nucleus and ventromedial hypothalamic nucleus

scientific article published in March 2003

An Implementation of a Spike-Response Model With Escape Noise Using an Avalanche Diode

scientific article published on 01 June 2011

An electrophysiological and morphological investigation of the projections of growth hormone-releasing peptide-6-responsive neurons in the rat arcuate nucleus to the median eminence and to the paraventricular nucleus

scientific article published in March 1999

An intrinsic vasopressin system in the olfactory bulb is involved in social recognition

scientific article

Bifurcations of emergent bursting in a neuronal network

scientific article

Bistability in the activity of vasopressin cells

Bistability with hysteresis in the activity of vasopressin cells

scientific article published in February 2007

Central release of oxytocin and the ventromedial hypothalamus.

scientific article published on November 2007

Circulating secretin activates supraoptic nucleus oxytocin and vasopressin neurons via noradrenergic pathways in the rat.

scientific article

Coding of odors in the anterior olfactory nucleus

scientific article published on 01 November 2019

Coherent peptide-mediated activity in a neuronal network controlled by subcellular signaling pathway: experiments and modeling

scientific article published on 20 January 2010

Dendritic peptide release and peptide-dependent behaviours

scientific article

Direct and indirect effects of cannabinoids on in vitro GABA release in the rat arcuate nucleus

scientific article published on 2 March 2010

Discharge patterning in rat olfactory bulb mitral cells in vivo

scientific article

Effect of progesterone on the activation of neurones of the supraoptic nucleus during parturition

scientific article published on 01 November 2000

Effects of alpha-melanocyte-stimulating hormone on magnocellular oxytocin neurones and their activation at intromission in male rats

scientific article published in September 2006

Effects of cholecystokinin in the supraoptic nucleus and paraventricular nucleus are negatively modulated by leptin in 24-h fasted lean male rats

scientific article

Effects of optogenetic stimulation of vasopressinergic retinal afferents on suprachiasmatic neurones

scientific article published on 01 December 2019

Emergent decision-making behaviour and rhythm generation in a computational model of the ventromedial nucleus of the hypothalamus.

scientific article published on 3 June 2019

Emergent synchronous bursting of oxytocin neuronal network

scientific article (publication date: 2008)

Endogenous activation of supraoptic nucleus kappa-opioid receptors terminates spontaneous phasic bursts in rat magnocellular neurosecretory cells

scientific article published on 22 February 2006

Endogenous prolactin-releasing peptide regulates food intake in rodents

scientific journal article

Estimation of parameters for a mathematical model of growth hormone secretion.

scientific article published in November 2004

Excitatory synaptic drive offsets opioid inhibition of oxytocin neurons

scientific article

GABAergic projection from the arcuate nucleus to the supraoptic nucleus in the rat

scientific article published on 01 March 2000

Ghrelin, reward and motivation

scientific article published on 25 April 2013

Growth hormone-releasing hormone and morphine attenuate growth hormone secretagogue-induced activation of the arcuate nucleus in the male rat.

scientific article published in August 1999

Gut instinct: body weight homeostasis in health and obesity

scientific article

Hypothalamic expression of NPY mRNA, vasopressin mRNA and CRF mRNA in response to food restriction and central administration of the orexigenic peptide GHRP-6

scientific article published on 01 March 2005

Increased sensitivity of monoamine release in the supraoptic nucleus in late pregnancy: region- and stimulus-dependent responses

scientific article published on 18 January 2010

Induction of c-fos in magnocellular neurosecretory neurons. A link between electrical activity and peptide synthesis?

scientific article

Information coding in vasopressin neurons--the role of asynchronous bistable burst firing

scientific article published on 14 March 2013

Intracellular calcium stores regulate activity-dependent neuropeptide release from dendrites

scientific article published in July 2002

Intranasal Oxytocin: Myths and Delusions

scientific article published on 11 May 2015

Intranasal application of vasopressin fails to elicit changes in brain immediate early gene expression, neural activity and behavioural performance of rats

scientific article published on July 2013

Jacques Benoit Lecture. Information processing in the hypothalamus: peptides and analogue computation

scientific article

Kappa-opioid restraint of oxytocin secretion: plasticity through pregnancy

scientific article published in December 1997

Mathematical modelling in neuroendocrinology

scientific article published on June 2008

Measuring Oxytocin and Vasopressin: Bioassays, Immunoassays and Random Numbers

scientific article

Metabolic and stress-related roles of prolactin-releasing peptide

scientific article published on February 2010

Modelling the hypothalamic control of growth hormone secretion

scientific article published in December 2005

Modelling the in vivo spike activity of phasically-firing vasopressin cells.

scientific article published in December 2010

Models of electrical activity: calibration and prediction testing on the same cell

scientific article

Morphine withdrawal increases intrinsic excitability of oxytocin neurons in morphine-dependent rats

scientific article published in January 2005

Naloxone-induced supersensitivity of oxytocin neurones to opioid antagonists.

scientific article published on July 1998

Neural Control of the Posterior Pituitary Gland (Neurohypophysis)

Neural substrates underlying interactions between appetite stress and reward

scientific article published on 19 April 2012

Neuroendocrine Networks

Neuroendocrine mechanisms of change in food intake during pregnancy: a potential role for brain oxytocin

scientific article published on 14 April 2007

Neuronal activation in the hypothalamus and brainstem during feeding in rats

scientific article published in October 2006

Neurotransmitters and peptides: whispered secrets and public announcements

scientific article published on 09 October 2008

Overactivation of corticotropin-releasing factor receptor type 1 and aquaporin-4 by hypoxia induces cerebral edema

scientific article

Oxytocin Neurones: Intrinsic Mechanisms Governing the Regularity of Spiking Activity

scientific article published on 30 December 2015

Oxytocin and Appetite

Oxytocin and appetite

scientific article published on January 2008

Oxytocin and the maternal brain

scientific article published on 06 August 2008

Oxytocin, feeding, and satiety

scientific article published on 20 March 2013

Oxytocin: A citation network analysis of 10 000 papers

scientific article published in 2021

Oxytocinase in the female rat hypothalamus: a novel mechanism controlling oxytocin neurones during lactation.

scientific article published in April 2014

Peripheral insulin administration enhances the electrical activity of oxytocin and vasopressin neurones in vivo

scientific article published on 27 February 2020

Phasic firing in vasopressin cells: understanding its functional significance through computational models

scientific article

Phasic spike patterning in rat supraoptic neurones in vivo and in vitro

scientific article

Polyuria, Polydipsia, and Poly(A) Tails: Insights into the Adaptive Nature of the Cellular Stress Response Pathways

scientific article published on 01 December 2011

Population dynamics in vasopressin cells

scientific article published on 30 July 2008

Presynaptic actions of endocannabinoids mediate alpha-MSH-induced inhibition of oxytocin cells

scientific article published on 3 November 2005

Priming in oxytocin cells and in gonadotrophs

scientific article published on 6 November 2007

Proteomics: inspiring new hypotheses in the vasopressin system

scientific article published in July 2007

Publishing the data behind the data (Show me yours, I'll show you mine)

scientific article

Regulation of activity-dependent dendritic vasopressin release from rat supraoptic neurones.

scientific article published on 24 February 2005

Regulation of neuronal nitric oxide synthase mRNA expression in the rat magnocellular neurosecretory system

scientific article published on 01 October 2004

Regulation of oxytocin secretion

scientific article

Reply to: Improving Research Standards to Restore Trust in Intranasal Oxytocin

scientific article published on 03 September 2015

Reply to: Intranasal Oxytocin Mechanisms Can Be Better Understood, but Its Effects on Social Cognition and Behavior Are Not to Be Sniffed At.

scientific article published on 2 July 2015

Sexual behaviour and neuronal activation in the vomeronasal pathway and hypothalamus of food-deprived male rats

scientific article published in April 2012

Social touch promotes interfemale communication via activation of parvocellular oxytocin neurons

scientific article published on 27 July 2020

Somatodendritic dynorphin release: orchestrating activity patterns of vasopressin neurons

scientific article published on November 2007

Spike patterning in oxytocin neurons: Capturing physiological behaviour with Hodgkin-Huxley and integrate-and-fire models.

scientific article

Spike triggered hormone secretion in vasopressin cells; a model investigation of mechanism and heterogeneous population function

scientific article

Spontaneous discharge characteristic of neurons in the ventromedial nucleus of the rat hypothalamus in vivo.

scientific article published on 30 July 2008

Steroidal influences on oxytocin neurones

Suppressed oxytocin neuron responses to immune challenge in late pregnant rats: a role for endogenous opioids

scientific article published in March 2006

Systemic leptin increases the electrical activity of supraoptic nucleus oxytocin neurones in virgin and late pregnant rats

scientific article

Temporal dissociation of the feedback effects of dendritically co-released peptides on rhythmogenesis in vasopressin cells.

scientific article published in January 2004

The Peptide Oxytocin Antagonist F-792, When Given Systemically, Does Not Act Centrally in Lactating Rats

scientific article published on 24 October 2015

The involvement of actin, calcium channels and exocytosis proteins in somato-dendritic oxytocin and vasopressin release

scientific article published in 2012

The involvement of voltage-operated calcium channels in somato-dendritic oxytocin release

scientific article

The magnocellular oxytocin system, the fount of maternity: adaptations in pregnancy

scientific article

The rat suprachiasmatic nucleus: the master clock ticks at 30 Hz

scientific article

The spiking and secretory activity of oxytocin neurones in response to osmotic stimulation: a computational model

scientific article published on 09 June 2019

c-jun mRNA expression in the hypothalamus of hypertensive rats

scientific article published in July 1993

List of works by Gareth Leng

"Eating addiction", rather than "food addiction", better captures addictive-like eating behavior

60 YEARS OF NEUROENDOCRINOLOGY: The posterior pituitary, from Geoffrey Harris to our present understanding

A Direct Neurokinin B Projection from the Arcuate Nucleus Regulates Magnocellular Vasopressin Cells of the Supraoptic Nucleus

A population model of vasopressin release

Actions of neuropeptide Y and growth hormone secretagogues in the arcuate nucleus and ventromedial hypothalamic nucleus

An Implementation of a Spike-Response Model With Escape Noise Using an Avalanche Diode

An electrophysiological and morphological investigation of the projections of growth hormone-releasing peptide-6-responsive neurons in the rat arcuate nucleus to the median eminence and to the paraventricular nucleus

An intrinsic vasopressin system in the olfactory bulb is involved in social recognition

Bifurcations of emergent bursting in a neuronal network

Bistability in the activity of vasopressin cells

Bistability with hysteresis in the activity of vasopressin cells

Central release of oxytocin and the ventromedial hypothalamus.

Circulating secretin activates supraoptic nucleus oxytocin and vasopressin neurons via noradrenergic pathways in the rat.

Coding of odors in the anterior olfactory nucleus

Coherent peptide-mediated activity in a neuronal network controlled by subcellular signaling pathway: experiments and modeling

Dendritic peptide release and peptide-dependent behaviours

Direct and indirect effects of cannabinoids on in vitro GABA release in the rat arcuate nucleus

Discharge patterning in rat olfactory bulb mitral cells in vivo

Effect of progesterone on the activation of neurones of the supraoptic nucleus during parturition

Effect of progesterone on the activation of neurones of the supraoptic nucleus during parturition

Effects of alpha-melanocyte-stimulating hormone on magnocellular oxytocin neurones and their activation at intromission in male rats

Effects of cholecystokinin in the supraoptic nucleus and paraventricular nucleus are negatively modulated by leptin in 24-h fasted lean male rats

Effects of optogenetic stimulation of vasopressinergic retinal afferents on suprachiasmatic neurones

Emergent decision-making behaviour and rhythm generation in a computational model of the ventromedial nucleus of the hypothalamus.

Emergent synchronous bursting of oxytocin neuronal network

Endogenous activation of supraoptic nucleus kappa-opioid receptors terminates spontaneous phasic bursts in rat magnocellular neurosecretory cells

Endogenous prolactin-releasing peptide regulates food intake in rodents

Estimation of parameters for a mathematical model of growth hormone secretion.

Excitatory synaptic drive offsets opioid inhibition of oxytocin neurons

GABAergic projection from the arcuate nucleus to the supraoptic nucleus in the rat

Ghrelin, reward and motivation

Growth hormone-releasing hormone and morphine attenuate growth hormone secretagogue-induced activation of the arcuate nucleus in the male rat.

Gut instinct: body weight homeostasis in health and obesity

Hypothalamic expression of NPY mRNA, vasopressin mRNA and CRF mRNA in response to food restriction and central administration of the orexigenic peptide GHRP-6

Increased sensitivity of monoamine release in the supraoptic nucleus in late pregnancy: region- and stimulus-dependent responses

Induction of c-fos in magnocellular neurosecretory neurons. A link between electrical activity and peptide synthesis?

Information coding in vasopressin neurons--the role of asynchronous bistable burst firing

Intracellular calcium stores regulate activity-dependent neuropeptide release from dendrites

Intranasal Oxytocin: Myths and Delusions

Intranasal application of vasopressin fails to elicit changes in brain immediate early gene expression, neural activity and behavioural performance of rats

Jacques Benoit Lecture. Information processing in the hypothalamus: peptides and analogue computation

Kappa-opioid restraint of oxytocin secretion: plasticity through pregnancy

Mathematical modelling in neuroendocrinology

Measuring Oxytocin and Vasopressin: Bioassays, Immunoassays and Random Numbers

Metabolic and stress-related roles of prolactin-releasing peptide

Modelling the hypothalamic control of growth hormone secretion

Modelling the in vivo spike activity of phasically-firing vasopressin cells.

Models of electrical activity: calibration and prediction testing on the same cell

Morphine withdrawal increases intrinsic excitability of oxytocin neurons in morphine-dependent rats

Naloxone-induced supersensitivity of oxytocin neurones to opioid antagonists.

Neural Control of the Posterior Pituitary Gland (Neurohypophysis)

Neural substrates underlying interactions between appetite stress and reward

Neuroendocrine Networks

Neuroendocrine mechanisms of change in food intake during pregnancy: a potential role for brain oxytocin

Neuronal activation in the hypothalamus and brainstem during feeding in rats

Neurotransmitters and peptides: whispered secrets and public announcements

Overactivation of corticotropin-releasing factor receptor type 1 and aquaporin-4 by hypoxia induces cerebral edema

Oxytocin Neurones: Intrinsic Mechanisms Governing the Regularity of Spiking Activity

Oxytocin and Appetite

Oxytocin and appetite

Oxytocin and the maternal brain

Oxytocin, feeding, and satiety

Oxytocin: A citation network analysis of 10 000 papers

Oxytocinase in the female rat hypothalamus: a novel mechanism controlling oxytocin neurones during lactation.

Peripheral insulin administration enhances the electrical activity of oxytocin and vasopressin neurones in vivo

Phasic firing in vasopressin cells: understanding its functional significance through computational models

Phasic spike patterning in rat supraoptic neurones in vivo and in vitro

Polyuria, Polydipsia, and Poly(A) Tails: Insights into the Adaptive Nature of the Cellular Stress Response Pathways

Population dynamics in vasopressin cells

Presynaptic actions of endocannabinoids mediate alpha-MSH-induced inhibition of oxytocin cells

Priming in oxytocin cells and in gonadotrophs

Proteomics: inspiring new hypotheses in the vasopressin system

Publishing the data behind the data (Show me yours, I'll show you mine)

Regulation of activity-dependent dendritic vasopressin release from rat supraoptic neurones.

Regulation of neuronal nitric oxide synthase mRNA expression in the rat magnocellular neurosecretory system

Regulation of oxytocin secretion

Reply to: Improving Research Standards to Restore Trust in Intranasal Oxytocin

Reply to: Intranasal Oxytocin Mechanisms Can Be Better Understood, but Its Effects on Social Cognition and Behavior Are Not to Be Sniffed At.

Sexual behaviour and neuronal activation in the vomeronasal pathway and hypothalamus of food-deprived male rats