Advanced search

Authors whose works are in public domain in at least one jurisdiction

List of works by Eric Verdin

'Candidatus phytoplasma phoenicium' sp. nov., a novel phytoplasma associated with an emerging lethal disease of almond trees in Lebanon and Iran

scientific article

50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond

scientific article published on 30 December 2014

A Novel Sirtuin-3 Inhibitor, LC-0296, Inhibits Cell Survival and Proliferation, and Promotes Apoptosis of Head and Neck Cancer Cells

scientific article

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

scientific article published on 30 April 2020

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

scientific article

A genetically novel, narrow-host-range isolate of cucumber mosaic virus (CMV) from rosemary

scientific article

A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein

scientific article

A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP.

scientific article published on 22 March 2007

A point mutation in the HIV-1 Tat responsive element is associated with postintegration latency

scientific article published on June 1996

AROuSing SIRT1: identification of a novel endogenous SIRT1 activator.

scientific article published on November 2007

Acetate metabolism and aging: An emerging connection

scientific article published on 15 May 2010

Acetylation of Tat defines a cyclinT1-independent step in HIV transactivation

scientific article published in July 2003

Acetylation of mitochondrial proteins

scientific article published on January 2009

Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity

article

Acetylphosphate: a novel link between lysine acetylation and intermediary metabolism in bacteria

scientific article published in July 2013

Activation of SIRT3 by the NAD⁺ precursor nicotinamide riboside protects from noise-induced hearing loss

scientific article

Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition

scientific article published on December 2006

Adipsic hypernatremia in a patient with pseudotumor cerebri and the primary empty sella syndrome

scholarly article

An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients

scientific article (publication date: 2013)

Angiopoietin-1 and vascular endothelial growth factor regulation of leukocyte adhesion to endothelial cells: role of nuclear receptor-77

scientific article

Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4.

scientific article published in September 1998

Author Correction: Senescent cells promote tissue NAD<sup>+</sup> decline during ageing via the activation of CD38<sup>+</sup> macrophages

scientific article published on 10 December 2020

BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.

scientific article published on February 2012

Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases

scientific article

CNS SIRT3 expression is altered by reactive oxygen species and in Alzheimer's disease

scientific article

Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation

scientific article (publication date: December 2010)

Cell biology. Stress response and aging

scientific article published in February 2009

Characterization of a human RPD3 ortholog, HDAC3 ⬇️

scientific article published on March 17, 1998

Chronic inflammation in the etiology of disease across the life span

scientific article published on 05 December 2019

Circadian profiles of blood glucose and plasma free insulin during treatment with semisynthetic and biosynthetic human insulin, and comparison with conventional monocomponent preparations

scientific article published on 01 January 1983

Class II histone deacetylases: versatile regulators

scientific article

Combination of biological screening in a cellular model of viral latency and virtual screening identifies novel compounds that reactivate HIV-1

scientific article

Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription

scientific article

Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases

scientific article (publication date: 12 April 2002)

Conserved metabolic regulatory functions of sirtuins

scientific article

Control of cytomegalovirus lytic gene expression by histone acetylation

scientific article published on March 2002

Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7.

scholarly article

CpG methylation controls reactivation of HIV from latency

scientific article published on 21 August 2009

CpG methylation controls reactivation of HIV from latency

Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

scientific article

Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors

scientific article published on 25 February 2007

Destabilization of ERBB2 transcripts by targeting 3' untranslated region messenger RNA associated HuR and histone deacetylase-6

scientific article published on July 2008

Dietary restriction: standing up for sirtuins

scientific article published on August 2010

Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T Cells.

scientific article

Dual-color HIV reporters trace a population of latently infected cells and enable their purification

scientific article published on 6 September 2013

Duration of nuclear NF-kappaB action regulated by reversible acetylation

scientific article (publication date: 31 August 2001)

Effect of inhibitors of histone deacetylase on the induction of cell differentiation in murine and human erythroleukemia cell lines

scientific article published on July 2005

Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR

scientific article

Epigenetic regulation of HIV latency

scientific article published on January 2011

Epigenetic regulation of HIV-1 latency by cytosine methylation

scientific article

Expression of histone deacetylase 8, a class I histone deacetylase, is restricted to cells showing smooth muscle differentiation in normal human tissues

scientific article

FOXO1 promotes HIV latency by suppressing ER stress in T cells

scientific article published on 15 June 2020

Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription.

scientific article published on June 2005

HAT trick: p300, small molecule, inhibitor

scientific article published in May 2010

HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism

scientific article

HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells.

scientific article

HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis

scientific article (publication date: May 2003)

HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells.

scientific article published on 11 June 2015

HIV latency: experimental systems and molecular models.

scientific article published on May 2012

HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals

scientific article published on July 2010

HIV reproducibly establishes a latent infection after acute infection of T cells in vitro.

scientific article

HIV-1 chromatin, transcription, and the regulatory protein Tat.

scientific article published on January 2014

Histone Deacetylase 7 mediates tissue-specific autoimmunity via control of innate effector function in invariant Natural Killer T Cells.

scientific article

Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM

scientific article

Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytes

scientific article

Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes

scientific article published on 11 March 2011

Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility.

scientific article

Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo

scientific article (publication date: 21 September 2001)

Identification and characterization of an enhancer in the coding region of the genome of human immunodeficiency virus type 1.

scientific article

Immune Hyperactivation of HIV-1-Infected T Cells Mediated by Tat and the CD28 Pathway

article

Immunosenescence and HIV.

scientific article published on 02 June 2012

Impact papers on aging in 2009.

scientific article

In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus.

scientific article published on 2 June 2010

Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies.

scientific article

Inhibitors of the NAD(+)-Dependent Protein Desuccinylase and Demalonylase Sirt5

scientific article

Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis

scientific article

Ketone bodies as signaling metabolites.

scientific article

Knockdown of XAB2 enhances all-trans retinoic acid-induced cellular differentiation in all-trans retinoic acid-sensitive and -resistant cancer cells.

scientific article published in February 2007

Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy

scientific article published on 02 October 2019

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

scientific journal article

Measurement of mammalian histone deacetylase activity

scientific article published in January 2004

Metabolic regulation, mitochondria and the life-prolonging effect of rapamycin: a mini-review

scientific article published on 30 August 2012

MicroRNA-155 Reinforces HIV Latency.

scientific article published on 14 April 2015

MicroRNAs of the miR-17∼92 family are critical regulators of T(FH) differentiation

scientific article published on 30 June 2013

Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype

scientific article published on 9 December 2015

Mitochondrial Protein Acylation and Intermediary Metabolism: Regulation by Sirtuins and Implications for Metabolic Disease ⬇️

scientific article published on October 18, 2012

Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases

scientific article published on 21 February 2013

Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice

scientific article

Mitochondrial sirtuins

scientific article published on 07 January 2010

Mitochondrial sirtuins: regulators of protein acylation and metabolism

scientific article published on 16 August 2012

Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation

scientific article

Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes

scientific journal article

NAD⁺ in aging, metabolism, and neurodegeneration.

scientific article

NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation

scientific article published on December 2005

Nonisotopic substrate for assaying both human zinc and NAD+-dependent histone deacetylases

scientific article published on 01 August 2003

Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance.

scientific article

Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors

scientific article published on November 2006

Partial chromosome sequence of Spiroplasma citri reveals extensive viral invasion and important gene decay.

scientific article

Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs)

scientific article

Platform-independent and label-free quantitation of proteomic data using MS1 extracted ion chromatograms in skyline: application to protein acetylation and phosphorylation

scientific article

Preparation of enzymatically active recombinant class III protein deacetylases.

scientific article

Prostratin antagonizes HIV latency by activating NF-kappaB.

scientific article

Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation

scientific article

Pyridylalanine-containing hydroxamic acids as selective HDAC6 inhibitors

scientific article

Reactivation of latent HIV by histone deacetylase inhibitors.

scientific article published on 18 March 2013

Reactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation

scientific article published on 24 October 2013

Receptor‐interacting protein (RIP) and Sirtuin‐3 (SIRT3) are on opposite sides of anoikis and tumorigenesis ⬇️

scientific article published on June 6, 2012

Regulation of global acetylation in mitosis through loss of histone acetyltransferases and deacetylases from chromatin.

scientific article

Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase

scientific article

Regulatory signal transduction pathways for class IIa histone deacetylases

scientific article published on 04 May 2010

Rejuvenating SIRT1 activators

scientific article published in May 2013

Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency

scientific article

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

scientific article

SIRT1 and SIRT3 Deacetylate Homologous Substrates: AceCS1,2 and HMGCS1,2 ⬇️

scientific article published on June 1, 2011

SIRT1 deacetylates RORγt and enhances Th17 cell generation

scientific article published on 27 April 2015

SIRT1 deacetylates RORγt and enhances Th17 cell generation

scientific article published on 18 May 2015

SIRT1 regulates HIV transcription via Tat deacetylation

scientific article

SIRT3 and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase

scientific article

SIRT3 and cancer: tumor promoter or suppressor?

scientific article

SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production

scientific article

SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome

scientific article

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

scientific article

SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism

scientific article

SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK ⬇️

scientific article published on November 1, 2013

SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target

scientific article

SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks

scientific journal article

SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease

scientific article published on 23 November 2020

Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity

scientific article

Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages

scientific article published on 16 November 2020

Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation

scientific article published on 08 July 2013

Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site

scientific article published on 11 October 2013

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

scientific article published on 20 September 2010

Sirtuin-3 (SIRT3) and the Hallmarks of Cancer

scientific article published on March 2013

Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer.

scientific article

Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production

scientific article

Sirtuins: Sir2-related NAD-dependent protein deacetylases

scientific article

Stable integrant-specific differences in bimodal HIV-1 expression patterns revealed by high-throughput analysis

scientific article published on 04 October 2019

Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain

scientific article

Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode

scientific article published on 13 February 2008

Subtype selective substrates for histone deacetylases

scientific article published in October 2004

Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor

scientific article

Tat Acetylation: A Regulatory Switch between Early and Late Phases in HIV Transcription Elongation

article

Tat acetylation: a regulatory switch between early and late phases in HIV transcription elongation

scientific article

The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription.

scientific article published in March 2010

The Longevity of Sirtuins ⬇️

scientific article published on December 27, 2012

The Nef protein of HIV-1 associates with rafts and primes T cells for activation

scientific article

The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter

scientific article

The emerging role of class II histone deacetylases

scientific article published in 2001

The first identification of lysine malonylation substrates and its regulatory enzyme ⬇️

scientific article

The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases

scientific article

The growing landscape of lysine acetylation links metabolism and cell signalling

scientific article

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

scientific article

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase

scientific article

The many faces of sirtuins: Coupling of NAD metabolism, sirtuins and lifespan

scientific article

The nexus of chromatin regulation and intermediary metabolism.

scientific article

The restricted nature of HIV-1 tropism for cultured neural cells

scientific article published on December 1992

The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons.

scientific article

The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation

scientific article

Therapy for latent HIV-1 infection: the role of histone deacetylase inhibitors

scientific article published on 29 January 2014

Thiobarbiturates as sirtuin inhibitors: virtual screening, free-energy calculations, and biological testing

scientific article

Three Rules for HIV Latency: Location, Location, and Location ⬇️

scientific article published on June 12, 2013

Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells

scientific article published on 6 February 2012

Tissue-resident macrophages are productively infected ex vivo by primary X4 isolates of human immunodeficiency virus type 1.

scientific article published on April 2005

Towards an HIV cure: a global scientific strategy

scientific article

Transcriptional suppression of in vitro-integrated human immunodeficiency virus type 1 does not correlate with proviral DNA methylation

scientific article

Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain

scientific article

Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes.

scientific article published on 14 November 2011

Understanding HIV latency: the road to an HIV cure

scientific article

Viral gene drive in herpesviruses

scientific article published on 28 September 2020

Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism.

scientific article published on 2 December 2012

Zmynd15 encodes a histone deacetylase-dependent transcriptional repressor essential for spermiogenesis and male fertility

scientific journal article

β-hydroxybutyrate: much more than a metabolite

scientific article published on 19 August 2014

Paulina is supported by:

About Paulina

Help