Search filters

List of works by James Hamilton

13C MAS NMR studies of crystalline cholesterol and lipid mixtures modeling atherosclerotic plaques

scientific article published on November 1996

A 13C nuclear magnetic resonance study of free fatty acid incorporation in acylated lipids in differentiating preadipocytes

scientific article published on May 1998

A comparative study of the backbone dynamics of two closely related lipid binding proteins: bovine heart fatty acid binding protein and porcine ileal lipid binding protein.

scientific article

A model for fatty acid transport into the brain.

scientific article published on September 2007

A mouse model for pathogen-induced chronic inflammation at local and systemic sites

scientific article

A multinuclear solid-state NMR study of phospholipid-cholesterol interactions. Dipalmitoylphosphatidylcholine-cholesterol binary system

scientific article published on 01 October 1995

A solid-state NMR study of phospholipid-cholesterol interactions: sphingomyelin-cholesterol binary systems

scientific article

Acipimox, an inhibitor of lipolysis, attenuates atherogenesis in LDLR-null mice treated with HIV protease inhibitor ritonavir

scientific article published on 17 September 2009

Angiotensin receptor blockade with candesartan attenuates atherosclerosis, plaque disruption, and macrophage accumulation within the plaque in a rabbit model

scientific article

Application of MRI to detect high-risk atherosclerotic plaque

scientific article published on 01 May 2011

Binding of 13-HODE and 15-HETE to phospholipid bilayers, albumin, and intracellular fatty acid binding proteins. implications for transmembrane and intracellular transport and for protection from lipid peroxidation

scientific article

Brain uptake and utilization of fatty acids, lipids & lipoproteins: recommendations for future research

scientific article published on September 2007

Brain uptake and utilization of fatty acids, lipids and lipoproteins: application to neurological disorders

scientific article published on September 2007

Brain uptake and utilization of fatty acids: applications to peroxisomal biogenesis diseases.

scientific article

Brain uptake and utilization of fatty acids: recommendations for future research.

scientific article published in April 2001

CD36 binds oxidized low density lipoprotein (LDL) in a mechanism dependent upon fatty acid binding

scientific article

CD36 enhances fatty acid uptake by increasing the rate of intracellular esterification but not transport across the plasma membrane

scientific article published on 03 October 2013

CSF-1 and cell cycle control in macrophages

scientific article

Caveolins sequester FA on the cytoplasmic leaflet of the plasma membrane, augment triglyceride formation, and protect cells from lipotoxicity.

scientific article

Colony-stimulating factor-1 (CSF-1) receptor-mediated macrophage differentiation in myeloid cells: a role for tyrosine 559-dependent protein phosphatase 2A (PP2A) activity

scientific article

Conformation and inhibitory properties of peptides based on the tissue kallikrein-aprotinin complex

scientific article published on 01 June 1991

Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis

scientific article published on January 2008

Correspondence of fatty acid and drug binding sites on human serum albumin: a two-dimensional nuclear magnetic resonance study

scientific article published on 19 February 2013

Crystal structure of CETP: new hopes for raising HDL to decrease risk of cardiovascular disease?

scientific article

Cytokine regulation of granulocyte-macrophage colony stimulating factor and macrophage colony-stimulating factor production in human arterial smooth muscle cells

scientific article published in March 1993

Detection of thrombus size and protein content by ex vivo magnetization transfer and diffusion weighted MRI

scientific article

Direct effects of fatty acids and other charged lipids on ion channel activity in smooth muscle cells

scientific article published on February 1995

Dissociation of long and very long chain fatty acids from phospholipid bilayers

scientific article published on 01 December 1996

Distinct lipid a moieties contribute to pathogen-induced site-specific vascular inflammation

scientific article

Early-life sodium exposure unmasks susceptibility to stroke in hyperlipidemic, hypertensive heterozygous Tg25 rats transgenic for human cholesteryl ester transfer protein

scientific article

Effect of PEG molecular weight on stability, T₂ contrast, cytotoxicity, and cellular uptake of superparamagnetic iron oxide nanoparticles (SPIONs)

scientific article published on 12 May 2014

Effect of disease progression on liver apparent diffusion coefficient and T2 values in a murine model of hepatic fibrosis at 11.7 Tesla MRI

scientific article published on October 11, 2011

Effect of disease progression on liver apparent diffusion coefficient values in a murine model of NASH at 11.7 Tesla MRI.

scientific article

Effects of Acetaldehyde on Hepatocyte Glycerol Uptake and Cell Size: Implication of Aquaporin 9

scientific article published on February 5, 2011

Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes

scientific article

Effects of thiol antioxidant β-mercaptoethanol on diet-induced obese mice

scientific article

Eicosapentaenoic acid, but not oleic acid, stimulates beta-oxidation in adipocytes

scientific article published on August 2005

Energy translocation across cell membranes and membrane models

scientific article

Enhancement of macrophage survival and DNA synthesis by oxidized-low-density-lipoprotein (LDL)-derived lipids and by aggregates of lightly oxidized LDL

scientific article

Esterification of free fatty acids in adipocytes: a comparison between octanoate and oleate

scientific article published on July 2000

Ex vivo identification of atherosclerotic plaque calcification by a 31P solid-state magnetic resonance imaging technique

scientific article published in December 2006

Extracellular mutations of non-obese diabetic mouse FcgammaRI modify surface expression and ligand binding.

scientific article

Fast diffusion of very long chain saturated fatty acids across a bilayer membrane and their rapid extraction by cyclodextrins: implications for adrenoleukodystrophy

scientific article published on 28 September 2009

Fast flip-flop of cholesterol and fatty acids in membranes: implications for membrane transport proteins

scientific article

Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice

scientific article published on February 2008

Fat depot origin affects fatty acid handling in cultured rat and human preadipocytes

scientific article

Fatty acid binding proteins reduce 15-lipoxygenase-induced oxygenation of linoleic acid and arachidonic acid.

scientific article published in May 1997

Fatty acid flip-flop in a model membrane is faster than desorption into the aqueous phase

scientific article published on 12 August 2008

Fatty acid flip-flop in phospholipid bilayers is extremely fast

scientific article published on 01 September 1995

Fatty acid transport and metabolism in HepG2 cells.

scientific article published on 27 October 2005

Fatty acid transport: difficult or easy?

scientific article

Fatty acid transport: the diffusion mechanism in model and biological membranes

scientific article published on 01 April 2001

Fatty acids are rapidly delivered to and extracted from membranes by methyl-beta-cyclodextrin.

scientific article published on January 2010

Fatty-acid-binding protein from the flight muscle of Locusta migratoria: evolutionary variations in fatty acid binding.

scientific article

Fibroblast and neutrophil collagenases cleave at two sites in the cartilage aggrecan interglobular domain

scientific article

Flexibility is a likely determinant of binding specificity in the case of ileal lipid binding protein

scientific article

Free fatty acids modulate intermembrane trafficking of cholesterol by increasing lipid mobilities: novel 13C NMR analyses of free cholesterol partitioning

scientific article

G1 phase arrest of human smooth muscle cells by heparin, IL-4 and cAMP is linked to repression of cyclin D1 and cdk2

scientific article published in August 1997

Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis

scientific article

Glucagon-like peptide 1 stimulates lipolysis in clonal pancreatic beta-cells (HIT).

scientific article

Granulocyte colony-stimulating factor-stimulated proliferation of myeloid cells: mode of cell cycle control by a range of inhibitors

scientific article published on October 1996

Hapten-specific tolerance in mice. I. Induction with hapten-coupled syngeneic erythrocytes

scientific article published on 01 April 1974

Hapten-specific tolerance in mice. II. Adoptive transfer studies and evidence for unresponsiveness in the B cells

scientific article published on 01 April 1974

Hapten-specific tolerance: unresponsiveness in the T cell-depleted population

Healthy obese persons: how can they be identified and do metabolic profiles stratify risk?

scientific article published on October 2013

High-field 13C NMR Studies of certain normal and abnormal human plasma lipoproteins

scientific article published on December 1976

How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids?

scientific article

How fatty acids bind to proteins: the inside story from protein structures

scientific article

Hydrolysis of a phospholipid in an inert lipid matrix by phospholipase A2: a 13C NMR study

scientific article published on 01 August 1989

Identification of High-Risk Plaques by MRI and Fluorescence Imaging in a Rabbit Model of Atherothrombosis

scientific article published on 8 October 2015

Identification of atherosclerotic lipid deposits by diffusion-weighted imaging

scientific article

Identification of cholesteryl esters in human carotid atherosclerosis by ex vivo image-guided proton MRS.

scientific article

Identification of different lipid phases and calcium phosphate deposits in human carotid artery plaques by MAS NMR spectroscopy

scientific article published in February 1998

Identification of phosphoproteins specific to granulocyte colony-stimulating factor-mediated signaling using 2D-SDS-PAGE.

scientific article published on February 1997

In vivo detection of vulnerable atherosclerotic plaque by MRI in a rabbit model

scientific article published in March 2010

In vivo magnetic resonance imaging of experimental thrombosis in a rabbit model

scientific article

In vivo molecular imaging of acute and subacute thrombosis using a fibrin-binding magnetic resonance imaging contrast agent

scientific article

Incorporation of [1-13C]oleate into cellular triglycerides in differentiating 3T3L1 cells

scientific article published on August 1999

Insider access: pepducin symposium explores a new approach to GPCR modulation

scientific article published in November 2009

Interactions between fatty acids and alpha-synuclein

scientific article

Interactions of a very long chain fatty acid with model membranes and serum albumin. Implications for the pathogenesis of adrenoleukodystrophy

scientific article published on September 1995

Interactions of acyl carnitines with model membranes: a (13)C-NMR study

scientific article

Interactions of acyl-coenzyme A with phosphatidylcholine bilayers and serum albumin

scientific article published on 01 January 1992

Interactions of lyso 1-palmitoylphosphatidylcholine with phospholipids: a 13C and 31P NMR study

scientific article published on 01 April 1995

Interactions of myristic acid with bovine serum albumin: a 13C NMR study.

scientific article

Interactions of oleic acid with liver fatty acid binding protein: a carbon-13 NMR study

scientific article published on 01 January 1988

Interactions of triglycerides with phospholipids: incorporation into the bilayer structure and formation of emulsions

scientific article published on 01 March 1989

Interactions of very long-chain saturated fatty acids with serum albumin

article

Interfacial conformation of dipalmitoylglycerol and dipalmitoylphosphatidylcholine in phospholipid bilayers

scientific article published on 01 November 1992

Lipoprotein-X: carbon-13 nuclear magnetic resonance studies on native, reconstituted, and model systems

scientific article published on 01 September 1980

Locating high-affinity fatty acid-binding sites on albumin by x-ray crystallography and NMR spectroscopy

scientific article

Location of high and low affinity fatty acid binding sites on human serum albumin revealed by NMR drug-competition analysis

scientific article published on 30 June 2006

Locations of the three primary binding sites for long-chain fatty acids on bovine serum albumin

scientific article published on March 1991

MRI of atherothrombosis associated with plaque rupture

scientific article published on 4 November 2004

Magic-angle spinning and solution 13C nuclear magnetic resonance studies of medium- and long-chain cholesteryl esters in model bilayers

article

Magnetization transfer magnetic resonance of human atherosclerotic plaques ex vivo detects areas of high protein density

scientific article

Measuring the adsorption of Fatty acids to phospholipid vesicles by multiple fluorescence probes

scientific article

Mechanism of cellular uptake of long-chain fatty acids: Do we need cellular proteins?

scientific article

Medium-chain Fatty acids attenuate agonist-stimulated lipolysis, mimicking the effects of starvation

scientific article published on April 2004

Medium-chain fatty acid binding to albumin and transfer to phospholipid bilayers.

scientific article

Medium-chain oil reduces fat mass and down-regulates expression of adipogenic genes in rats

scientific article published on June 2003

Medium-chain versus long-chain triacylglycerol emulsion hydrolysis by lipoprotein lipase and hepatic lipase: implications for the mechanisms of lipase action

scientific article

Mice deficient in phosphofructokinase-M have greatly decreased fat stores

scientific article

Molecular organization and motions of cholesteryl esters in crystalline and liquid crystalline phases: a 13C and 1H magic angle spinning NMR study

article

Molecular organization and motions of crystalline monoacylglycerols and diacylglycerols: a C-13 MASNMR study

scientific article

NMR assignment and structural characterization of the fatty acid binding protein from the flight muscle of Locusta migratoria

scientific article published in April 2003

NMR reveals molecular interactions and dynamics of fatty acid binding to albumin

scientific article published on 09 August 2013

Natural abundance carbon-13 nuclear magnetic resonance spectra of human serum lipoproteins

scientific article published in April 1973

Natural abundance carbon-13 nuclear magnetic resonance spectra of the canine sciatic nerve

scientific article published on 01 August 1973

New insights into the roles of proteins and lipids in membrane transport of fatty acids.

scientific article

Oleate-induced formation of fat cells with impaired insulin sensitivity

scientific article

Oxidized LDL can induce macrophage survival, DNA synthesis, and enhanced proliferative response to CSF-1 and GM-CSF

scientific article published on 01 January 1999

Oxidized LDL can promote human monocyte survival

scientific article published in October 2000

Phase behavior and bilayer properties of fatty acids: hydrated 1:1 acid-soaps

scientific article published on 01 May 1986

Phase behavior and crystalline structures of cholesteryl ester mixtures: a C-13 MASNMR study

scientific article

Porphyromonas gingivalis accelerates inflammatory atherosclerosis in the innominate artery of ApoE deficient mice

scientific article

Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen

scientific article

Quantification in situ of crystalline cholesterol and calcium phosphate hydroxyapatite in human atherosclerotic plaques by solid-state magic angle spinning NMR.

scientific article

Quantification of cholesteryl esters in human and rabbit atherosclerotic plaques by magic-angle spinning (13)C-NMR

scientific article published on 01 December 2000

Rapid Flip-flop of Oleic Acid across the Plasma Membrane of Adipocytes

scientific article published in Journal of Biological Chemistry

Regeneration of antidigoxin binding activity in an antibody by changes surrounding the original binding defect

scientific article

Regions of low endothelial shear stress colocalize with positive vascular remodeling and atherosclerotic plaque disruption: an in vivo magnetic resonance imaging study.

scientific article

Regulation of Toll-like receptor (TLR)2 and TLR4 on CD14dimCD16+ monocytes in response to sepsis-related antigens

scientific article

Regulation of urokinase plasminogen activator gene transcription in the RAW264 murine macrophage cell line by macrophage colony-stimulating factor (CSF-1) is dependent upon the level of cell-surface receptor.

scientific article

Relationship of obesity with osteoporosis

scientific article published on 13 February 2007

Retinaldehyde represses adipogenesis and diet-induced obesity.

scientific article

Role of caveolin-1 and cholesterol in transmembrane fatty acid movement.

scientific article published on March 2006

Roundtable Discussion of Session 1: Mechanisms of Lipid Uptake and Transport in the Brain

scientific article published on 01 September 2007

Roundtable discussion of session 2: lipoproteins and polyunsaturated fatty acids

scientific article published on 01 September 2007

Roundtable discussion of session 3: eicosanoids in brain function

scientific article published on 01 September 2007

Roundtable discussion of session 4: fatty acids and lipids in brain disorders

scientific article published on 01 September 2007

Solution Structure and Backbone Dynamics of Human Liver Fatty Acid Binding Protein: Fatty Acid Binding Revisited

scientific article

Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid metabolism

scientific article

Solution structure of human intestinal fatty acid binding protein: implications for ligand entry and exit

scientific article

Solution structure of ileal lipid binding protein in complex with glycocholate

scientific article

Spatio-temporal texture (SpTeT) for distinguishing vulnerable from stable atherosclerotic plaque on dynamic contrast enhancement (DCE) MRI in a rabbit model

scientific article published on April 2014

Structural requirements for charged lipid molecules to directly increase or suppress K+ channel activity in smooth muscle cells. Effects of fatty acids, lysophosphatidate, acyl coenzyme A and sphingosine

scientific article

Study of the miscibility of cholesteryl oleate in a matrix of ceramide, cholesterol and fatty acid.

scientific article

Sulfonylureas rapidly cross phospholipid bilayer membranes by a free-diffusion mechanism

scientific article published in October 2003

Targeted binding of PLA microparticles with lipid-PEG-tethered ligands.

scientific article

Temperature-dependent molecular motions of cholesterol esters: a carbon-13 nuclear magnetic resonance study

scientific article published on 01 December 1982

The effect of free cholesterol on the solubilization of cholesteryl oleate in phosphatidylcholine bilayers: A 13C-NMR study

scientific article published on August 1986

The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease

scientific article published on February 2003

The influence of pericardial fat upon left ventricular function in obese females: evidence of a site-specific effect

scientific article

The ionization behavior of fatty acids and bile acids in micelles and membranes

scientific article published on 01 September 1984

The relationship of ectopic lipid accumulation to cardiac and vascular function in obesity and metabolic syndrome

scientific article published on 29 October 2009

The x-ray crystal structure refinements of normal human transthyretin and the amyloidogenic Val-30-->Met variant to 1.7-A resolution

scientific article

Thermotropic properties and molecular dynamics of cholesteryl ester rich very low density lipoproteins: effect of hydrophobic core on polar surface.

scientific article

Transbilayer movement of bile acids in model membranes.

scientific article

Transfer of oleic acid between albumin and phospholipid vesicles

scientific article published on January 1986

Transforming growth factor beta stimulates urokinase-type plasminogen activator and DNA synthesis, but not prostaglandin E2 production, in human synovial fibroblasts

scientific article published on August 1991

Transport of fatty acids across membranes by the diffusion mechanism.

scientific article

Transthyretin: a review from a structural perspective.

scientific article

c-fos antisense DNA inhibits proliferation of osteoclast progenitors in osteoclast development but not macrophage differentiation in vitro

scientific article published in June 1996