List of works - Tie-Lin Yang

A family-based association study identified CYP17 as a candidate gene for obesity susceptibility in Caucasians

scientific article

A follow-up association study of two genetic variants for bone mineral density variation in Caucasians.

scientific article published on 09 December 2011

A genome wide association study between copy number variation (CNV) and human height in Chinese population

scientific article published in December 2010

Association analyses of CYP19 gene polymorphisms with height variation in a large sample of Caucasian nuclear families

scientific article published on 30 May 2006

Bivariate genome linkage analysis suggests pleiotropic effects on chromosomes 20p and 3p for body fat mass and lean mass

scientific article

Bivariate genome-wide association analyses identified genes with pleiotropic effects for femoral neck bone geometry and age at menarche

scientific article

Comprehensive association analyses of IGF1, ESR2, and CYP17 genes with adult height in Caucasians

scientific article published on 18 June 2008

Comprehensive functional annotation of susceptibility SNPs prioritized 10 genes for schizophrenia

article

Comprehensive review and annotation of susceptibility SNPs associated with obesity-related traits

scientific article published on 12 March 2018

Copy number variation in CNP267 region may be associated with hip bone size

scientific article

Copy number variation on chromosome 10q26.3 for obesity identified by a genome-wide study

scientific article published on 21 November 2012

Copy number variations at the Prader-Willi syndrome region on chromosome 15 and associations with obesity in whites

scientific article published on 13 January 2011

Detecting epistasis within chromatin regulatory circuitry reveals CAND2 as a novel susceptibility gene for obesity

scientific article published on 01 May 2018

ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma.

scientific article published on 2 January 2018

Epistatic interactions between genomic regions containing the COL1A1 gene and genes regulating osteoclast differentiation may influence femoral neck bone mineral density

scientific article published in March 2007

Functional analyses reveal the essential role of SOX6 and RUNX2 in the communication of chondrocyte and osteoblast

scientific article published on 12 September 2014

Gene expression profiles indicate tissue-specific obesity regulation changes and strong obesity relevant tissues.

scientific article published on 20 November 2017

Gene-gene interaction between RBMS3 and ZNF516 influences bone mineral density

scientific article

Genetic analysis identifies DDR2 as a novel gene affecting bone mineral density and osteoporotic fractures in Chinese population

scientific article

Genetic and environmental correlations of bone mineral density at different skeletal sites in females and males

scientific article

Genetic association study of common mitochondrial variants on body fat mass

scientific article

Genetic variants in the SOX6 gene are associated with bone mineral density in both Caucasian and Chinese populations.

scientific article

Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups

scientific article published on 26 February 2009

Genome-wide association and replication studies identified TRHR as an important gene for lean body mass

scientific article published on 05 March 2009

Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci

scientific article

Genome-wide association study for femoral neck bone geometry

scientific article

Genome-wide association study identified CNP12587 region underlying height variation in Chinese females

scientific article

Genome-wide association study identified copy number variants important for appendicular lean mass

scientific article

Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis

scientific article

Genome-wide association study identifies HMGN3 locus for spine bone size variation in Chinese

scientific article published on 25 September 2011

Genome-wide association study identifies two novel loci containing FLNB and SBF2 genes underlying stature variation

scientific article

Genome-wide association study of copy number variants suggests LTBP1 and FGD4 are important for alcohol drinking

scientific article

Genome-wide association study of copy number variation identified gremlin1 as a candidate gene for lean body mass

scientific article

Genome-wide association study suggested copy number variation may be associated with body mass index in the Chinese population

scientific article published on 20 February 2009

Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis

scientific article

Genome-wide pathway-based association study implicates complement system in the development of Kashin-Beck disease in Han Chinese

scientific article published on 16 October 2014

Genomewide linkage scan for combined obesity phenotypes using principal component analysis

scientific article published on 6 January 2008

Genomewide linkage scan for quantitative trait loci underlying variation in age at menarche

scientific article published on 4 January 2006

HMGA2 is confirmed to be associated with human adult height

scientific article

IL21R and PTH may underlie variation of femoral neck bone mineral density as revealed by a genome-wide association study

scientific article

Impact of female cigarette smoking on circulating B cells in vivo: the suppressed ICOSLG, TCF3, and VCAM1 gene functional network may inhibit normal cell function

scientific article

In vivo genome-wide expression study on human circulating B cells suggests a novel ESR1 and MAPK3 network for postmenopausal osteoporosis

scientific article published on May 2008

Integrating regulatory features data for prediction of functional disease-associated SNPs.

scientific article published on 16 August 2017

Mendelian randomization analyses support causal relationships between brain imaging-derived phenotypes and risk of psychiatric disorders

scientific article published in 2022

Mitochondria-wide association study of common variants in osteoporosis

scientific article

Multiple functional variants at 13q14 risk locus for osteoporosis regulate RANKL expression through long-range super-enhancer.

scientific article published on 12 March 2018

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density

scientific article

Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD.

scientific article

Phenome-wide investigation of the causal associations between childhood BMI and adult trait outcomes: a two-sample Mendelian randomization study

scientific article published in 2021

Polymorphism in the insulin-like growth factor 1 gene is associated with age at menarche in caucasian females

scientific article published on 21 March 2007

Polymorphisms in the estrogen receptor genes are associated with hip fractures in Chinese

article

Polymorphisms of estrogen-biosynthesis genes CYP17 and CYP19 may influence age at menarche: a genetic association study in Caucasian females

scientific article published on 16 June 2006

Polymorphisms of the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study

scientific article published on 24 May 2006

Publisher Correction: ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma.

scientific article published on 6 April 2018

RTN4B-mediated suppression of Sirtuin 2 activity ameliorates β-amyloid pathology and cognitive impairment in Alzheimer's disease mouse model

scientific article published on 23 July 2020

Regulatory element-based prediction identifies new susceptibility regulatory variants for osteoporosis.

scientific article

Robust and comprehensive analysis of 20 osteoporosis candidate genes by very high-density single-nucleotide polymorphism screen among 405 white nuclear families identified significant association and gene-gene interaction

scientific article published on November 2006

Runs of homozygosity identify a recessive locus 12q21.31 for human adult height

scientific article

Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study

scientific article published on 30 October 2012

The Causal Relationships Between Gut Microbiota, Brain Volume, and Intelligence: A Two-Step Mendelian Randomization Analysis

scientific article published in 2024

The fat mass and obesity associated gene, FTO, is also associated with osteoporosis phenotypes

scientific article

The regulation-of-autophagy pathway may influence Chinese stature variation: evidence from elder adults

scientific article

Trans-omics pathway analysis suggests that eQTLs contribute to chondrocyte apoptosis of Kashin-Beck disease through regulating apoptosis pathway expression

scientific article published on 11 October 2014

Variations in RANK gene are associated with adult height in Caucasians

scientific article published in July 2007

Whole genome distribution and ethnic differentiation of copy number variation in Caucasian and Asian populations

scientific article

List of works by Tie-Lin Yang

A family-based association study identified CYP17 as a candidate gene for obesity susceptibility in Caucasians

A follow-up association study of two genetic variants for bone mineral density variation in Caucasians.

A genome wide association study between copy number variation (CNV) and human height in Chinese population

Association analyses of CYP19 gene polymorphisms with height variation in a large sample of Caucasian nuclear families

Bivariate genome linkage analysis suggests pleiotropic effects on chromosomes 20p and 3p for body fat mass and lean mass

Bivariate genome-wide association analyses identified genes with pleiotropic effects for femoral neck bone geometry and age at menarche

Comprehensive association analyses of IGF1, ESR2, and CYP17 genes with adult height in Caucasians

Comprehensive functional annotation of susceptibility SNPs prioritized 10 genes for schizophrenia

Comprehensive review and annotation of susceptibility SNPs associated with obesity-related traits

Copy number variation in CNP267 region may be associated with hip bone size

Copy number variation on chromosome 10q26.3 for obesity identified by a genome-wide study

Copy number variations at the Prader-Willi syndrome region on chromosome 15 and associations with obesity in whites

Detecting epistasis within chromatin regulatory circuitry reveals CAND2 as a novel susceptibility gene for obesity

ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma.

Epistatic interactions between genomic regions containing the COL1A1 gene and genes regulating osteoclast differentiation may influence femoral neck bone mineral density

Functional analyses reveal the essential role of SOX6 and RUNX2 in the communication of chondrocyte and osteoblast

Gene expression profiles indicate tissue-specific obesity regulation changes and strong obesity relevant tissues.

Gene-gene interaction between RBMS3 and ZNF516 influences bone mineral density

Genetic analysis identifies DDR2 as a novel gene affecting bone mineral density and osteoporotic fractures in Chinese population

Genetic and environmental correlations of bone mineral density at different skeletal sites in females and males

Genetic association study of common mitochondrial variants on body fat mass

Genetic variants in the SOX6 gene are associated with bone mineral density in both Caucasian and Chinese populations.

Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups

Genome-wide association and replication studies identified TRHR as an important gene for lean body mass

Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci

Genome-wide association study for femoral neck bone geometry

Genome-wide association study identified CNP12587 region underlying height variation in Chinese females

Genome-wide association study identified copy number variants important for appendicular lean mass

Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis

Genome-wide association study identifies HMGN3 locus for spine bone size variation in Chinese

Genome-wide association study identifies two novel loci containing FLNB and SBF2 genes underlying stature variation

Genome-wide association study of copy number variants suggests LTBP1 and FGD4 are important for alcohol drinking

Genome-wide association study of copy number variation identified gremlin1 as a candidate gene for lean body mass

Genome-wide association study suggested copy number variation may be associated with body mass index in the Chinese population

Genome-wide copy-number-variation study identified a susceptibility gene, UGT2B17, for osteoporosis

Genome-wide pathway-based association study implicates complement system in the development of Kashin-Beck disease in Han Chinese

Genomewide linkage scan for combined obesity phenotypes using principal component analysis

Genomewide linkage scan for quantitative trait loci underlying variation in age at menarche

HMGA2 is confirmed to be associated with human adult height

IL21R and PTH may underlie variation of femoral neck bone mineral density as revealed by a genome-wide association study

Impact of female cigarette smoking on circulating B cells in vivo: the suppressed ICOSLG, TCF3, and VCAM1 gene functional network may inhibit normal cell function

In vivo genome-wide expression study on human circulating B cells suggests a novel ESR1 and MAPK3 network for postmenopausal osteoporosis

Integrating regulatory features data for prediction of functional disease-associated SNPs.

Mendelian randomization analyses support causal relationships between brain imaging-derived phenotypes and risk of psychiatric disorders

Mitochondria-wide association study of common variants in osteoporosis

Multiple functional variants at 13q14 risk locus for osteoporosis regulate RANKL expression through long-range super-enhancer.

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density

Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD.

Phenome-wide investigation of the causal associations between childhood BMI and adult trait outcomes: a two-sample Mendelian randomization study

Polymorphism in the insulin-like growth factor 1 gene is associated with age at menarche in caucasian females

Polymorphisms in the estrogen receptor genes are associated with hip fractures in Chinese

Polymorphisms of estrogen-biosynthesis genes CYP17 and CYP19 may influence age at menarche: a genetic association study in Caucasian females

Polymorphisms of the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study

Publisher Correction: ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma.

RTN4B-mediated suppression of Sirtuin 2 activity ameliorates β-amyloid pathology and cognitive impairment in Alzheimer's disease mouse model

Regulatory element-based prediction identifies new susceptibility regulatory variants for osteoporosis.

Robust and comprehensive analysis of 20 osteoporosis candidate genes by very high-density single-nucleotide polymorphism screen among 405 white nuclear families identified significant association and gene-gene interaction

Runs of homozygosity identify a recessive locus 12q21.31 for human adult height

Suggestion of GLYAT gene underlying variation of bone size and body lean mass as revealed by a bivariate genome-wide association study

The Causal Relationships Between Gut Microbiota, Brain Volume, and Intelligence: A Two-Step Mendelian Randomization Analysis

The fat mass and obesity associated gene, FTO, is also associated with osteoporosis phenotypes

The regulation-of-autophagy pathway may influence Chinese stature variation: evidence from elder adults

Trans-omics pathway analysis suggests that eQTLs contribute to chondrocyte apoptosis of Kashin-Beck disease through regulating apoptosis pathway expression

Variations in RANK gene are associated with adult height in Caucasians

Whole genome distribution and ethnic differentiation of copy number variation in Caucasian and Asian populations