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List of works by Charles V. Mobbs

Acute induction of gene expression in brain and liver by insulin-induced hypoglycemia

scientific article published in April 2005

Adrenal neuropeptide Y mRNA but not preproenkephalin mRNA induction by stress is impaired by aging in Fischer 344 rats

scientific article published in April 1998

Alterations in hypothalamic serotonergic-catecholaminergic relationships in aging C57BL/6J female mice

scientific article

Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals

scientific article published on 31 December 2006

Block the FAS, lose the fat.

scientific article

Cell-specific expression of preproenkephalin intronic heteronuclear RNA in the rat forebrain

scientific article

Central pro-opiomelanocortin gene delivery results in hypophagia, reduced visceral adiposity, and improved insulin sensitivity in genetically obese Zucker rats

scientific article published on August 2003

Changes in estrogenic regulation of estrogen receptor alpha mRNA and progesterone receptor mRNA in the female rat hypothalamus during aging: an in situ hybridization study

scientific article published on 01 September 2000

Changes in neurotensin mRNA by estrogen in the female rat preoptic area during aging: an in situ hybridization histochemistry study

scientific article published in December 1998

Changes in preproenkephalin messenger RNA level in the rat ventromedial hypothalamus during the estrous cycle

scientific article published on 01 January 1995

Chemosensory and caloric mechanisms influence distinct components of mortality rate

scientific article published on 28 August 2008

Comparative proteomic analysis of the ATP-sensitive K+ channel complex in different tissue types

scientific article published on 03 January 2013

Comprehensive polypeptide analysis of microdissected rat brain areas: combining 2-dimensional gel electrophoresis with 2-dimensional HPLC and immunoanalysis and sequencing procedures

scientific article published on 01 July 1989

Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology

scientific article published on 26 September 2005

Considerations in the quantitative analysis of autoradiograms from 2-dimensional gels

scientific article published on 01 July 1989

Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

scientific article published on 21 January 2016

D-chiro-Inositol enhances effects of hypothalamic toxin gold-thioglucose

scientific article

DNA Methylation and DNase-Hypersensitive Sites in the 5' Flanking and Transcribed Regions of the Rat Preproenkephalin Gene: Studies of Mediobasal Hypothalamus

scientific article published on 01 December 1993

Daily nasal inoculation with the insulin gene ameliorates diabetes in mice

scientific article published in January 2004

Differential regulation of proenkephalin gene expression by estrogen in the ventromedial hypothalamus of male and female rats: implications for the molecular basis of a sexually differentiated behavior

scientific article published on December 1990

Estradiol Regulation of Estrogen Receptor Messenger Ribonucleic Acid in Rat Mediobasal Hypothalamus: An in situ Hybridization Study

scientific article

Estradiol impairs hypothalamic molecular responses to hypoglycemia.

scientific article published on 13 May 2009

Estradiol induction of proenkephalin messenger RNA in hypothalamus: dose-response and relation to reproductive behavior in the female rat.

scientific article published in June 1990

Estrogen increases HIP-70/PLC-alpha messenger ribonucleic acid in the rat uterus and hypothalamus

scientific article

Estrogen regulation of proenkephalin gene expression in the ventromedial hypothalamus of the rat: temporal qualities and synergism with progesterone

scientific article published in January 1989

Estrogenic regulation of heat shock protein 90 kDa in the rat ventromedial hypothalamus and uterus

scientific article published in April 1992

Evidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans

scientific article

Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes

scientific article

Fathead: the gain in brain falls mainly with leptin wane

scientific article published in February 2006

Genetic influences on glucose neurotoxicity, aging, and diabetes: a possible role for glucose hysteresis

scientific article published on January 1993

Glucokinase regulates reproductive function, glucocorticoid secretion, food intake, and hypothalamic gene expression

scientific article published on 11 January 2007

Glucose-induced metabolic memory in Schwann cells: prevention by PPAR agonists

scientific article

Hyperphagia and weight gain after gold-thioglucose: relation to hypothalamic neuropeptide Y and proopiomelanocortin

scientific article

Hyperprolactinemia fails to increase striatal dopamine receptors in male and female C57BL/6J mice

scientific article published in December 1984

Hypothalamic BDNF and obesity: found in translation

scientific article

Hypothalamic Fkbp51 is induced by fasting, and elevated hypothalamic expression promotes obese phenotypes

scientific article published on 7 February 2012

Hypothalamic Responses to Fasting Indicate Metabolic Reprogramming Away from Glycolysis Toward Lipid Oxidation ⬇️

scientific article published on September 29, 2010

Hypothalamic agouti-related protein messenger ribonucleic acid is inhibited by leptin and stimulated by fasting

scientific article

Hypothalamic glucose sensor: similarities to and differences from pancreatic beta-cell mechanisms.

scientific article

Impaired glucose signaling as a cause of obesity and the metabolic syndrome: the glucoadipostatic hypothesis.

scientific article

Impaired hypothalamic Fto expression in response to fasting and glucose in obese mice

scientific article published on 31 October 2011

Inhibition of agouti-related peptide expression by glucose in a clonal hypothalamic neuronal cell line is mediated by glycolysis, not oxidative phosphorylation

scientific article published on November 2007

Injection with gold thioglucose impairs sensitivity to glucose: evidence that glucose-responsive neurons are important for long-term regulation of body weight

scientific article published in September 1996

Laparotomy in mice induces blood cell expression of inflammatory and stress genes

scientific article

Lifespan is not determined by metabolic rate: evidence from fishes and C. elegans

scientific article published on 01 June 2004

Lobotomy of genes: use of RNA interference in neuroscience.

scientific article published on January 2004

Low-carbohydrate diets cause obesity, low-carbohydrate diets reverse obesity: a metabolic mechanism resolving the paradox

scientific article published on December 2006

Metabolic mystery: aging, obesity, diabetes, and the ventromedial hypothalamus.

scientific article published on 20 June 2013

Metabolic pathways that mediate inhibition of hypothalamic neurons by glucose.

scientific article published in January 2004

Mining microarrays for metabolic meaning: nutritional regulation of hypothalamic gene expression

scientific article published on 01 June 2004

Molecular hysteresis: residual effects of hormones and glucose on genes during aging

scientific article published on 01 July 1994

Naloxone, but not valsartan, preserves responses to hypoglycemia after antecedent hypoglycemia: role of metabolic reprogramming in counterregulatory failure.

scientific article

Obese gene expression: reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity

scientific article published on April 1996

PLC-alpha: a common mediator of the action of estrogen and other hormones?

scientific article published on September 1991

Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity

scientific article

Phorbol esters and forskolin infused into midbrain central gray facilitate lordosis

scientific article published on 01 November 1989

Prolactin receptor messenger RNA is synthesized by the epithelial cells of the choroid plexus

scientific article published in November 1992

Protection against hypoxic-ischemic injury in transgenic mice overexpressing Kir6.2 channel pore in forebrain

scientific article published in April 2004

Protection by dietary restriction in the YAC128 mouse model of Huntington's disease: Relation to genes regulating histone acetylation and HTT.

scientific article published on 16 October 2015

Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

scientific article

Regulation of peripheral metabolism by substrate partitioning in the brain.

scientific article

Resistance to diet-induced obesity is associated with increased proopiomelanocortin mRNA and decreased neuropeptide Y mRNA in the hypothalamus

scientific article published on 01 December 1999

Reversal of diabetic nephropathy by a ketogenic diet.

scientific article

Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling

scientific article published in November 2009

Roles of second-messenger systems and neuronal activity in the regulation of lordosis by neurotransmitters, neuropeptides, and estrogen: a review

scientific article published on January 1994

SOD isoforms play no role in lifespan in ad lib or dietary restricted conditions, but mutational inactivation of SOD-1 reduces life extension by cold

scientific article

Secrets of the lac operon. Glucose hysteresis as a mechanism in dietary restriction, aging and disease

scientific article published on January 2007

Sex differences in the regulation of heat shock protein 70 kDa and 90 kDa in the rat ventromedial hypothalamus by estrogen

scientific article published in November 1992

Sex steroids and fos expression in rat brain and uterus

scientific article published in August 1990

Sexual stimulation activates c-fos within estrogen-concentrating regions of the female rat forebrain

scientific article published on 01 October 1993

Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome.

scholarly article

Similarity of an estrogen-induced protein and a luteinizing hormone releasing hormone-induced protein.

scientific article published in April 1989

Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

scientific article

T lymphopenia in genetically obese-diabetic Wistar fatty rats: effects of body weight reduction on T cells

scientific article published in October 2000

Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance

scientific journal article

Temporal actions of 16 alpha-hydroxyestrone in the rat: comparisons of lordosis dynamics with other estrogen metabolites and between sexes

scientific article published on 01 September 1989

The "domino theory" of hunger: the hypothalamus is hot.

scientific article published in January 2007

The bradykinin BK2 receptor mediates angiotensin II receptor type 2 stimulated rat duodenal mucosal alkaline secretion

scientific article

The fatty acid synthase inhibitor cerulenin and feeding, like leptin, activate hypothalamic pro-opiomelanocortin (POMC) neurons

scientific article

The physiological function of the agouti-related peptide gene: the control of weight and metabolic rate

scientific article published in January 2003

Transgenic neuronal expression of proopiomelanocortin attenuates hyperphagic response to fasting and reverses metabolic impairments in leptin-deficient obese mice

scientific article published in November 2003

Treatment of Diabetes and Diabetic Complications With a Ketogenic Diet

scientific article

VGF ablation blocks the development of hyperinsulinemia and hyperglycemia in several mouse models of obesity

scientific journal article

Validated analysis of mortality rates demonstrates distinct genetic mechanisms that influence lifespan

scientific article published on 14 September 2008

Validated genomic approach to study differentially expressed genes in complex tissues.

scientific article published on October 2002

Ventromedial hypothalamic lesions produced by gold thioglucose do not impair induction of NPY mRNA in the arcuate nucleus by fasting

scientific article published in January 1996

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