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List of works by Carlos J Ciudad

A genomics approach identifies selective effects of trans-resveratrol in cerebral cortex neuron and glia gene expression

scientific article

A highly efficient electroporation method for the transfection of endothelial cells

scientific article published in January 2004

A novel DNA-binding motif in prostate tumor overexpressed-1 (PTOV1) required for the expression of ALDH1A1 and CCNG2 in cancer cells

scientific article published on 25 March 2019

A novel muscle DNA-binding activity in the GLUT1 promoter

scientific article published in March 2004

Activation of hepatocyte glycogen synthase by metabolic inhibitors

scientific article published on 01 November 1986

Alcohol enhances the psychostimulant and conditioning effects of mephedrone in adolescent mice; postulation of unique roles of D3 receptors and BDNF in place preference acquisition.

scientific article published on 30 July 2015

An intron is required for dihydrofolate reductase protein stability

scientific article

Anti-migratory and anti-angiogenic effect of p16: a novel localization at membrane ruffles and lamellipodia in endothelial cells

scientific article published in January 2004

Atorvastatin reduces CD68, FABP4, and HBP expression in oxLDL-treated human macrophages

scientific article published on May 2004

CD4 expression decrease by antisense oligonucleotides: inhibition of rat T CD4+ cell reactivity

scientific journal article

CYP1A1 is overexpressed upon incubation of breast cancer cells with a polyphenolic cocoa extract

scientific article

Cancer immunotherapy using PolyPurine Reverse Hoogsteen hairpins targeting the PD-1/PD-L1 pathway in human tumor cells

scientific article published in PLoS ONE

Cell-growth regulation of the hamster dihydrofolate reductase gene promoter by transcription factor Sp1.

scientific article

Characterization of the 5′-flanking region of the human transcription factor Sp3 gene

scientific article published in August 2005

Cloning and characterization of the 5'-flanking region of the human transcription factor Sp1 gene.

scientific article published on 9 April 2001

Cocoa flavanol metabolites activate HNF‐3β, Sp1, and NFY‐mediated transcription of apolipoprotein AI in human cells ⬇️

scientific article published on January 7, 2013

Coding polypurine hairpins cause target-induced cell death in breast cancer cells.

scientific article

Coffee Polyphenols Change the Expression of STAT5B and ATF-2 Modifying Cyclin D1 Levels in Cancer Cells ⬇️

scientific article published on August 7, 2012

Complexes of Pd(II) and Pt(II) with 9-aminoacridine: reactions with DNA and study of their antiproliferative activity.

scientific article published on January 2007

Control of glycogen synthase phosphorylation in isolated rat hepatocytes by epinephrine, vasopressin and glucagon

scientific article published on 01 August 1984

Correction of point mutations at the endogenous locus of the dihydrofolate reductase gene using repair-PolyPurine Reverse Hoogsteen hairpins in mammalian cells

scientific article published on 7 April 2016

Correction of the aprt Gene Using Repair-Polypurine Reverse Hoogsteen Hairpins in Mammalian Cells

scientific article published on 24 December 2019

Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins

scientific article published on 16 July 2020

Determination of Dihydrofolate Reductase Gene Amplification from Single Cell Colonies by Quantitative Polymerase Chain Reaction

scientific article published in January 1995

Determination of glucose-6-phosphatase activity using the glucose dehydrogenase-coupled reaction

scientific article published on 01 August 1988

Development and effects of immunoliposomes carrying an antisense oligonucleotide against DHFR RNA and directed toward human breast cancer cells overexpressing HER2.

scientific article

Different effects of glucagon and epinephrine on the kinetic properties of liver glycogen synthase

scientific article published on 01 January 1983

Differential induction of stearoyl-CoA desaturase and acyl-CoA oxidase genes by fibrates in HepG2 cells.

scientific article

Differentially expressed genes between high-risk human papillomavirus types in human cervical cancer cells

scientific article published on 14 February 2007

Effect of Differential Polyadenylation and Cell Growth Phase on Dihydrofolate Reductase mRNA Stability

scientific article published in Journal of Biological Chemistry

Effect of Polypurine Reverse Hoogsteen Hairpins on Relevant Cancer Target Genes in Different Human Cell Lines.

scientific article

Effects of glucagon and insulin on the cyclic AMP binding capacity of hepatocyte cyclic AMP-dependent protein kinase

scientific article published on 01 January 1987

Epicatechin and a cocoa polyphenolic extract modulate gene expression in human Caco-2 cells.

scientific article

Expression profiles of a human pancreatic cancer cell line upon induction of apoptosis search for modulators in cancer therapy

scientific article

Functional pharmacogenomics and toxicity of PolyPurine Reverse Hoogsteen hairpins directed against survivin in human cells

scientific article published on 22 June 2018

Gene expression profiles in rat mesenteric lymph nodes upon supplementation with conjugated linoleic acid during gestation and suckling

scientific article

Gene identification by cDNA arrays in HPV-positive cervical cancer.

scientific article published on September 2005

Glucose 6-phosphate plays a central role in the activation of glycogen synthase by glucose in hepatocytes

scientific article published on 01 December 1986

Glucose-6-phosphate dehydrogenase and transketolase modulate breast cancer cell metabolic reprogramming and correlate with poor patient outcome

scientific article published on 7 October 2017

Glycogen synthase activation by sugars in isolated hepatocytes

scientific article published on 01 July 1988

Glycogen synthase: a new activity ratio assay expressing a high sensitivity to the phosphorylation state

scientific article published on October 1979

Glycogen synthesis from glucose and fructose in hepatocytes from diabetic rats

scientific article

Health benefits of walnut polyphenols: An exploration beyond their lipid profile

scientific article published on 29 December 2015

Identification of novel Sp1 targets involved in proliferation and cancer by functional genomics.

scientific article

Improved design of PPRHs for gene silencing

scientific article

Inactivation of basal glycogen synthase by glucagon and epinephrine in hepatocytes from fed rats

scientific article published on 01 May 1986

Inhibition of CD4 expression by antisense oligonucleotides in PMA-treated lymphocytes

scientific article

Inhibition of cancer cell growth by ruthenium(II) cyclopentadienyl derivative complexes with heteroaromatic ligands.

scientific article

Insulin activation of basal hepatic glycogen synthase

scientific article published on 01 June 1981

Insulin inactivation of rat hepatocyte cyclic AMP-dependent protein kinase

scientific article published on 01 December 1981

Modulation of IMPDH2, survivin, topoisomerase I and vimentin increases sensitivity to methotrexate in HT29 human colon cancer cells

scientific article

Molecular and functional characterization of LRP1 promoter polymorphism c.1-25 C>G (rs138854007).

scientific article published on 8 January 2014

Networking of differentially expressed genes in human cancer cells resistant to methotrexate.

scientific article published on 4 September 2009

New π-arene ruthenium(II) piano-stool complexes with nitrogen ligands

scientific article

Overexpression of S100A4 in human cancer cell lines resistant to methotrexate

scientific article

Pentose phosphate cycle oxidative and nonoxidative balance: A new vulnerable target for overcoming drug resistance in cancer

scientific article published on December 2006

Phosphorylation of glycogen synthase in isolated rabbit hepatocytes

scientific article published on 01 June 1984

Polypurine Reverse Hoogsteen Hairpins as a Gene Silencing Tool for Cancer.

scientific article published in March 2017

Polypurine reverse Hoogsteen hairpins as a gene therapy tool against survivin in human prostate cancer PC3 cells in vitro and in vivo.

scientific article

Polypurine reverse-Hoogsteen (PPRH) oligonucleotides can form triplexes with their target sequences even under conditions where they fold into G-quadruplexes

scientific article

Protein kinase C inhibitors reduce phorbol ester-induced resistance to methotrexate in Chinese hamster ovary cells ⬇️

scientific article published on July 31, 1995

Purine enzyme profile in human colon-carcinoma cell lines and differential sensitivity to deoxycoformycin and 2'-deoxyadenosine in combination

scientific article published in July 1995

Regulation of Sp1 by cell cycle related proteins.

scientific article

Regulation of mitochondrial 3-hydroxy-3-methylglutaryl-coenzyme A synthase protein by starvation, fat feeding, and diabetes

scientific journal article

Repair of single-point mutations by polypurine reverse Hoogsteen hairpins

scientific article published on 14 October 2014

Retinoblastoma protein associates with SP1 and activates the hamster dihydrofolate reductase promoter

scientific article published in April 1998

Role of caveolin 1, E-cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells

scientific article

Rosiglitazone upregulates caveolin-1 expression in THP-1 cells through a PPAR-dependent mechanism

scientific article published on 16 August 2004

Sensitization of human erythroleukemia K562 cells resistant to methotrexate by inhibiting IMPDH.

scientific article published in January 2005

Short-term oleoyl-estrone treatment affects capacity to manage lipids in rat adipose tissue

scientific article

Silencing PD-1 and PD-L1: the potential of PolyPurine Reverse Hoogsteen hairpins for the elimination of tumor cells

scientific article published on 01 April 2019

Silencing of CD47 and SIRPα by Polypurine reverse Hoogsteen hairpins to promote MCF-7 breast cancer cells death by PMA-differentiated THP-1 cells

scientific article

Silencing of Foxp3 enhances the antitumor efficacy of GM-CSF genetically modified tumor cell vaccine against B16 melanoma.

scientific article

Sp1 involvement in the 4beta-phorbol 12-myristate 13-acetate (TPA)-mediated increase in resistance to methotrexate in Chinese hamster ovary cells

scientific article

Stability and immunogenicity properties of the gene-silencing polypurine reverse Hoogsteen hairpins.

scientific article

Strand displacement of double-stranded DNA by triplex-forming antiparallel purine-hairpins

scientific article

Synthesis of glycogen from fructose in the presence of elevated levels of glycogen phosphorylase a in rat hepatocytes

scientific article published on 01 March 1980

Targeting of sterically stabilised pH-sensitive liposomes to human T-leukaemia cells.

scientific article published on February 2005

The expression of retinoblastoma and Sp1 is increased by low concentrations of cyclin-dependent kinase inhibitors

scientific article

The inactivation of glycogen phosphorylase is not a prerequisite for the activation of liver glycogen synthase

scientific article published on March 1979

The redox state of cytochrome c modulates resistance to methotrexate in human MCF7 breast cancer cells

scientific article

Therapeutic targeting of tumor growth and angiogenesis with a novel anti-S100A4 monoclonal antibody

scientific article published on 4 September 2013

Transcriptional profiling of striatal neurons in response to single or concurrent activation of dopamine D2, adenosine A(2A) and metabotropic glutamate type 5 receptors: focus on beta-synuclein expression

scientific article published on 7 August 2012

Transcriptional regulation of aldo-keto reductase 1C1 in HT29 human colon cancer cells resistant to methotrexate: role in the cell cycle and apoptosis

scientific article published on 8 September 2007

Transcriptional regulation of the 5'-flanking region of the human transcription factor Sp3 gene by NF-1, c-Myb, B-Myb, AP-1 and E2F.

scientific article published on 10 March 2008

Transcriptional regulation of the human Sp1 gene promoter by the specificity protein (Sp) family members nuclear factor Y (NF-Y) and E2F.

scientific article

UDP-glucuronosyltransferase 1A6 overexpression in breast cancer cells resistant to methotrexate

scientific article published on 18 September 2010

Underexpression of miR-224 in methotrexate resistant human colon cancer cells.

scientific article

Up-regulation of the Kv3.4 potassium channel subunit in early stages of Alzheimer's disease.

scientific article

Urolithin A causes p21 up-regulation in prostate cancer cells.

scientific article published on 12 May 2015

Use of siRNAs and Antisense Oligonucleotides Against Survivin RNA to Inhibit Steps Leading to Tumor Angiogenesis

scientific article published in April 2004

Validation of miRNA-mRNA interactions by electrophoretic mobility shift assays

scientific article

Walnut polyphenol metabolites, urolithins A and B, inhibit the expression of the prostate-specific antigen and the androgen receptor in prostate cancer cells

scientific article published on November 2014

g-Nomic: a new pharmacogenetics interpretation software

scientific article published on 29 May 2019

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