List of works by Mary Jackson

2-aminoimidazoles collapse mycobacterial proton motive force and block the electron transport chain

scientific article published in Scientific Reports

2-aminoimidazoles potentiate ß-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing ß-lactamase secretion and increasing cell envelope permeability.

scientific article

A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in <i>Mycobacterium tuberculosis</i>

scientific article published on 22 February 2021

A Noncompetitive Inhibitor for Mycobacterium tuberculosis ’s Class IIa Fructose 1,6-Bisphosphate Aldolase

scientific article

A common mechanism of inhibition of the Mycobacterium tuberculosis mycolic acid biosynthetic pathway by isoxyl and thiacetazone

scientific article

A glycomic approach reveals a new mycobacterial polysaccharide

scientific article

A point mutation in the two-component regulator PhoP-PhoR accounts for the absence of polyketide-derived acyltrehaloses but not that of phthiocerol dimycocerosates in Mycobacterium tuberculosis H37Ra

scientific article

A single arabinan chain is attached to the phosphatidylinositol mannosyl core of the major immunomodulatory mycobacterial cell envelope glycoconjugate, lipoarabinomannan

scientific article

A small multidrug resistance-like transporter involved in the arabinosylation of arabinogalactan and lipoarabinomannan in mycobacteria

scientific article

AftD, a novel essential arabinofuranosyltransferase from mycobacteria

scientific article published on 04 August 2009

Aldehyde-resistant mycobacteria bacteria associated with the use of endoscope reprocessing systems

scientific article published on 10 February 2012

An oligopeptide transporter of Mycobacterium tuberculosis regulates cytokine release and apoptosis of infected macrophages

scientific journal article

Analysing nonsynonymous mutations between two Mycobacterium bovis strains with contrasting pathogenic profiles

scientific article published on 04 November 2019

Analysis of a panel of rapidly growing mycobacteria for resistance to aldehyde-based disinfectants

scientific article

Analysis of uracil phosphoribosyltransferase expression in Mycobacterium tuberculosis and evaluation of upp knockout strain in infected mice

scientific article published on 26 January 2017

Assembling of the Mycobacterium tuberculosis Cell Wall Core

scientific article published on 14 July 2016

Bacterial protein-O-mannosylating enzyme is crucial for virulence of Mycobacterium tuberculosis

scientific article published on 2 April 2013

Biochemical and microbiological evaluation of N-aryl urea derivatives against mycobacteria and mycobacterial hydrolases

scientific article published on 04 June 2019

Biosynthesis and translocation of unsulfated acyltrehaloses in Mycobacterium tuberculosis

scientific article

Biosynthesis of mycobacterial lipoarabinomannan: role of a branching mannosyltransferase

scientific journal article

Biosynthesis of the Methylthioxylose Capping Motif of Lipoarabinomannan in Mycobacterium tuberculosis

scientific article published on 11 January 2017

Biosynthetic origin of the galactosamine substituent of Arabinogalactan in Mycobacterium tuberculosis

scientific journal article

Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice

scientific journal article

Cell wall core galactofuran synthesis is essential for growth of mycobacteria

scientific article

Chapter 2: Biogenesis of the cell wall and other glycoconjugates of Mycobacterium tuberculosis

scientific article published on January 2009

Characterization of Arabinosyl Transfer Reactions in the Biosynthesis of Mycobacterial Cell Envelope (Lipo)Polysaccharides

scientific article published on 01 January 2019

Cloning and Partial Characterization of an Endo-α-(1→6)-d-Mannanase Gene from Bacillus circulans ⬇️

scientific article published on 11 December 2019

Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives

scientific article

Cooccurrence of free-living amoebae and nontuberculous Mycobacteria in hospital water networks, and preferential growth of Mycobacterium avium in Acanthamoeba lenticulata

scientific article published on 08 March 2013

Covalent modification of the Mycobacterium tuberculosis FAS-II dehydratase by Isoxyl and Thiacetazone

scientific article

Covalent modifications of polysaccharides in mycobacteria

scientific article published in February 2018

CpsA, a LytR-CpsA-Psr Family Protein in Mycobacterium marinum, Is Required for Cell Wall Integrity and Virulence

scientific article published on 4 May 2015

Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis

scientific article published on 22 April 2005

Cytokinin Signaling in Mycobacterium tuberculosis.

scientific article published on 19 June 2018

DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells

scientific article

Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity

scientific article published on December 2005

Deciphering the molecular basis of mycobacteria and lipoglycan recognition by the C-type lectin Dectin-2

scientific article published in Scientific Reports

Deficiency in mycolipenate- and mycosanoate-derived acyltrehaloses enhances early interactions of Mycobacterium tuberculosis with host cells

scientific article published in June 2003

Definition of the first mannosylation step in phosphatidylinositol mannoside synthesis. PimA is essential for growth of mycobacteria

scientific journal article

Design, synthesis and anti-tuberculosis activity of 1-adamantyl-3-heteroaryl ureas with improved in vitro pharmacokinetic properties

scientific article published on 26 February 2013

Design, synthesis and evaluation of indole-2-carboxamides with pan anti-mycobacterial activity

scientific article

Direct Inhibition of MmpL3 by Novel Antitubercular Compounds

scientific article published on 28 March 2019

Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.

scientific article

Disinfectant Susceptibility Profiling of Glutaraldehyde-Resistant Nontuberculous Mycobacteria

scientific article published on 2 May 2017

Disruption of the SucT acyltransferase in Mycobacterium smegmatis abrogates succinylation of cell envelope polysaccharides

scientific article published on 20 May 2019

Draft Genome Sequence of Mycobacterium chelonae Type Strain ATCC 35752.

scientific article published on 28 May 2015

Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis

scientific article published on September 1997

Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos.

scientific article published on 28 June 2018

Gene replacement in Mycobacterium chelonae: application to the construction of porin knock-out mutants

scientific article (publication date: 2014)

Genetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosis

scientific journal article

Genetics of Capsular Polysaccharides and Cell Envelope (Glyco)lipids

scientific article

Genome Sequence of an Epidemic Isolate of Mycobacterium abscessus subsp. bolletii from Rio de Janeiro, Brazil

scientific article published on 15 August 2013

Glycolytic and Non-glycolytic Functions of Mycobacterium tuberculosis Fructose-1,6-bisphosphate Aldolase, an Essential Enzyme Produced by Replicating and Non-replicating Bacilli

scientific article

Green Fluorescent Protein as a protein localization and topological reporter in mycobacteria

scientific article published on 10 April 2017

HLA-E Presents Glycopeptides from the Mycobacterium tuberculosis Protein MPT32 to Human CD8+ T cells

scientific article published on 4 July 2017

High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors

scientific article

High-level relatedness among Mycobacterium abscessus subsp. massiliense strains from widely separated outbreaks

scientific article published on March 2014

Identification and functional analysis of a galactosyltransferase capable of cholesterol glycolipid formation in the Lyme disease spirochete Borrelia burgdorferi

scientific article published on 01 June 2021

Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance

scientific article published on 23 September 2019

Identification of a Novel Mycobacterial Arabinosyltransferase Activity Which Adds an Arabinosyl Residue to α-d-Mannosyl Residues

scientific article published on 05 April 2016

Identification of a polyprenylphosphomannosyl synthase involved in the synthesis of mycobacterial mannosides

scientific journal article

Identification of the required acyltransferase step in the biosynthesis of the phosphatidylinositol mannosides of mycobacterium species

scientific journal article

Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis

scientific article

Impact of the deletion of the six mce operons in Mycobacterium smegmatis

scientific article published on 8 February 2012

Impact of the epoxide hydrolase EphD on the metabolism of mycolic acids in mycobacteria.

scientific article published on 22 February 2018

Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence

scientific journal article

Inactivation of fructose-1,6-bisphosphate aldolase prevents optimal co-catabolism of glycolytic and gluconeogenic carbon substrates in Mycobacterium tuberculosis

scientific article (publication date: May 2014)

Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope

scientific journal article

Increased virulence of an epidemic strain of Mycobacterium massiliense in mice

scientific article (publication date: 2011)

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

scientific journal article

Initiation of methylglucose lipopolysaccharide biosynthesis in mycobacteria

scientific article

Interactions of free-living amoebae with rice bacterial pathogens Xanthomonas oryzae pathovars oryzae and oryzicola

scientific article published in PLoS ONE

Interactions of free-living amoebae with the rice fungal pathogen, Rhizoctonia solani

scientific article published on 15 November 2019

Investigation of ABC transporter from mycobacterial arabinogalactan biosynthetic cluster

scientific article published on September 2011

Isoxyl activation is required for bacteriostatic activity against Mycobacterium tuberculosis

scientific article

Lipoarabinomannan of Mycobacterium: mannose capping by a multifunctional terminal mannosyltransferase

scientific journal article

Long-chain multiple methyl-branched fatty acid-containing lipids of Mycobacterium tuberculosis: biosynthesis, transport, regulation and biological activities

scientific article published on 9 October 2006

Long-term survival and virulence of Mycobacterium leprae in amoebal cysts

scientific article (publication date: December 2014)

LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis

scientific journal article

LprG-mediated surface expression of lipoarabinomannan is essential for virulence of Mycobacterium tuberculosis

scientific article

Mce3R, a TetR-type transcriptional repressor, controls the expression of a regulon involved in lipid metabolism in Mycobacterium tuberculosis

scientific journal article

Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen

scientific article

Mechanisms of Resistance Associated with the Inhibition of the Dehydration Step of Type II Fatty Acid Synthase in Mycobacterium tuberculosis

scientific article published on 11 December 2019

Mechanistic Insights into the Retaining Glucosyl-3-phosphoglycerate Synthase from Mycobacteria

scientific article

Metabolic profile of Mycobacterium smegmatis reveals Mce4 proteins are relevant for cell wall lipid homeostasis

MmpL3 as a Target for the Treatment of Drug-Resistant Nontuberculous Mycobacterial Infections.

scientific article published on 10 July 2018

Molecular basis of phosphatidyl-myo-inositol mannoside biosynthesis and regulation in mycobacteria

scientific article

Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria

scientific article

Mycobacterium bovis hosted by free-living-amoebae permits their long-term persistence survival outside of host mammalian cells and remain capable of transmitting disease to mice.

scientific article published on 5 June 2017

Mycobacterium talmoniae sp. nov., a slowly growing mycobacterium isolated from human respiratory samples

scientific article published on 15 August 2017

Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA.

scientific article published on 27 September 2017

Mycobacterium tuberculosis lipoprotein LprG binds lipoarabinomannan and determines its cell envelope localization to control phagolysosomal fusion

scientific article

N-D-aldopentofuranosyl-N'-[p-(isoamyloxy)phenyl]-thiourea derivatives: potential anti-TB therapeutic agents

scientific article

New insights into the biosynthesis of mycobacterial lipomannan arising from deletion of a conserved gene

scientific article

New insights into the early steps of phosphatidylinositol mannoside biosynthesis in mycobacteria: PimB' is an essential enzyme of Mycobacterium smegmatis

scientific journal article

Novel insights into the mechanism of inhibition of MmpL3, a target of multiple pharmacophores in Mycobacterium tuberculosis

scientific article

Optimization and Lead Selection of Benzothiazole Amide Analogs Toward a Novel Antimycobacterial Agent

scientific article published on 20 September 2018

Partial Saturation of Menaquinone in Mycobacterium tuberculosis: Function and Essentiality of a Novel Reductase, MenJ

scientific journal article

Phosphatidylinositol is an essential phospholipid of mycobacteria

scientific journal article

Phospholipases C are involved in the virulence of Mycobacterium tuberculosis

scientific journal article

Phylogenomics of Brazilian epidemic isolates of Mycobacterium abscessus subsp. bolletii reveals relationships of global outbreak strains

scientific article published on 18 September 2013

Polymethylated polysaccharides from Mycobacterium species revisited

scientific article published on 11 September 2008

Preliminary crystallographic analysis of GpgS, a key glucosyltransferase involved in methylglucose lipopolysaccharide biosynthesis in Mycobacterium tuberculosis

scientific article

Production of phthiocerol dimycocerosates protects Mycobacterium tuberculosis from the cidal activity of reactive nitrogen intermediates produced by macrophages and modulates the early immune response to infection

scientific article published in March 2004

Progress in targeting cell envelope biogenesis in Mycobacterium tuberculosis

scientific article published on July 2013

Purification and characterization of the acyltransferase involved in biosynthesis of the major mycobacterial cell envelope glycolipid--monoacylated phosphatidylinositol dimannoside.

scientific article published on 6 May 2014

RND transporters protect Corynebacterium glutamicum from antibiotics by assembling the outer membrane

scientific article

Rational Design, Synthesis, and Evaluation of New Selective Inhibitors of Microbial Class II (Zinc Dependent) Fructose Bis-phosphate Aldolases

scientific article

Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors

scientific article

Reduced local growth and spread but preserved pathogenicity of a DeltapurC Mycobacterium tuberculosis auxotrophic mutant in gamma interferon receptor-deficient mice after aerosol infection

scientific article

Regulation of mycolactone, the Mycobacterium ulcerans toxin, depends on nutrient source

scientific article (publication date: November 2013)

Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs

scientific article published on 6 July 2009

Role of the Mce1 transporter in the lipid homeostasis of Mycobacterium tuberculosis

scientific article published on 02 January 2014

Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability

scientific article

Signature-tagged transposon mutagenesis identifies novel Mycobacterium tuberculosis genes involved in the parasitism of human macrophages

scientific article published on 9 October 2006

Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA.

scientific article published on 11 March 2016

Structure-Function Profile of MmpL3, the Essential Mycolic Acid Transporter from Mycobacterium tuberculosis

scientific article published on September 2016

Structure-function relationships of membrane-associated GT-B glycosyltransferases

scientific article

Subfractionation and analysis of the cell envelope (lipo)polysaccharides of Mycobacterium tuberculosis

scientific article

Substrate-induced conformational changes in the essential peripheral membrane-associated mannosyltransferase PimA from mycobacteria: implications for catalysis

scientific article published on 11 June 2009

Sulfolipid deficiency does not affect the virulence of Mycobacterium tuberculosis H37Rv in mice and guinea pigs

scientific article

Synergistic Interactions of MmpL3 Inhibitors with Antitubercular Compounds In Vitro

scientific article published on 23 January 2017

Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics

scientific article

Synthesis and evaluation of new 2-aminothiophenes against Mycobacterium tuberculosis

scientific article

Synthesis, biological activity, and evaluation of the mode of action of novel antitubercular benzofurobenzopyrans substituted on A ring

scientific article published on October 2010

Taxonomic characterization of nine strains isolated from clinical and environmental specimens, and proposal of Corynebacterium tuberculostearicum sp. nov.

scientific article

The MmpL3 interactome reveals a complex crosstalk between cell envelope biosynthesis and cell elongation and division in mycobacteria

scientific article published on 24 July 2019

The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth

scientific journal article

The cell envelope glycoconjugates of Mycobacterium tuberculosis

scientific article

The cell surface receptor DC-SIGN discriminates between Mycobacterium species through selective recognition of the mannose caps on lipoarabinomannan

scientific article

The glycosyltransferases of Mycobacterium tuberculosis - roles in the synthesis of arabinogalactan, lipoarabinomannan, and other glycoconjugates

scientific article published on 29 January 2007

The immunomodulatory lipoglycans, lipoarabinomannan and lipomannan, are exposed at the mycobacterial cell surface

scientific article published on 09 June 2008

The mycobacterial cell envelope-lipids

scientific article

The presence of a galactosamine substituent on the arabinogalactan of Mycobacterium tuberculosis abrogates full maturation of human peripheral blood monocyte-derived dendritic cells and increases secretion of IL-10.

scientific article published on 14 May 2015

The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria

scientific article published on 27 April 2006

The structure-activity relationship of urea derivatives as anti-tuberculosis agents

scientific article

The virulence-associated two-component PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosis

scientific journal article

Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3

scientific article published on 13 June 2016

Transient requirement of the PrrA-PrrB two-component system for early intracellular multiplication of Mycobacterium tuberculosis

scientific journal article

Transporters Involved in the Biogenesis and Functionalization of the Mycobacterial Cell Envelope

scientific article published on 10 November 2020

Two-Way Regulation of MmpL3 Expression Identifies and Validates Inhibitors of MmpL3 Function in <i>Mycobacterium tuberculosis</i>

scientific article published on 15 December 2020

Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis

scientific article (publication date: 26 December 2003)

Updating and curating metabolic pathways of TB.

scientific article published on January 2013

Use of Synthetic Glycolipids to Probe the Number and Position of Arabinan Chains on Mycobacterial Arabinogalactan

scientific article published on 31 December 2020

Virulence attenuation of two Mas-like polyketide synthase mutants of Mycobacterium tuberculosis

scientific journal article

Yersinia pestis Survival and Replication in Potential Ameba Reservoir.

scientific article published in February 2018

p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis

scientific journal article

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