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List of works by Samia J. Khoury

A critical role for the programmed death ligand 1 in fetomaternal tolerance

scientific article

A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis

scientific article

A randomized controlled double-masked trial of albuterol add-on therapy in patients with multiple sclerosis.

scientific article

A tale of two STAT6 knock out mice in the induction of experimental autoimmune encephalomyelitis

scientific article published on 18 December 2008

Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis

scientific article published on 17 August 2009

An RNA profile identifies two subsets of multiple sclerosis patients differing in disease activity

scientific article

Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis

scientific article

Antigen-specific TGF-beta1 secretion with bovine myelin oral tolerization in multiple sclerosis

scientific article published on February 1996

Assessment by flow cytometry of intracellular cytokine production in the peripheral blood cells of renal transplant recipients

scientific article

Biomarkers

Brain MRI lesion load at 1.5T and 3T versus clinical status in multiple sclerosis.

scientific article

CD200R1 agonist attenuates mechanisms of chronic disease in a murine model of multiple sclerosis

scientific article

CTLA-4 is required for the induction of high dose oral tolerance.

scientific article

CTLA4Ig treatment in patients with multiple sclerosis: an open-label, phase 1 clinical trial.

scientific article published in September 2008

Cerebral pseudoatrophy or real atrophy after therapy in multiple sclerosis

scientific article published on 01 December 2010

Circulating microRNAs as biomarkers for disease staging in multiple sclerosis

scientific article

Class II MHC allopeptide-specific T-cell clones transfer delayed type hypersensitivity responses in vivo

article

Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus

scientific article published on 30 October 2013

Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis.

scientific article

Consensus guidelines for the diagnosis and treatment of multiple sclerosis

scientific article published on 22 April 2013

Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

scientific article

Cumulative administrations of gadolinium-based contrast agents: risks of accumulation and toxicity of linear vs macrocyclic agents

scientific article published on 01 March 2019

Cyclophosphamide modulates CD4+ T cells into a T helper type 2 phenotype and reverses increased IFN-gamma production of CD8+ T cells in secondary progressive multiple sclerosis

scientific article published on 01 January 2004

Cytokine shifts and tolerance in experimental autoimmune encephalomyelitis

scientific article published on January 2003

Cytokines in multiple sclerosis: from bench to bedside

scientific article

Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells

scientific article published on 21 June 2008

Daclizumab in treatment of multiple sclerosis patients

scientific article published on 09 January 2009

Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis

scientific article published on January 2009

Development, psychometric properties, and pilot norms of the first Arabic indigenous memory test: The Verbal Memory Arabic Test (VMAT)

scientific article published on 22 June 2020

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function

scientific article

Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway

scientific article

Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis

scientific article published on 26 June 2008

Effect of vitamin D replacement on immunological biomarkers in patients with multiple sclerosis

scientific article published on 20 May 2017

Efficacy and safety of natalizumab extended interval dosing

Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration

scientific article published on May 2007

Erratum: IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ Foxp3− effector T cells

scholarly article published in Nature Immunology

Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex

scientific article published in November 2004

Foxo1 Promotes Th9 Cell Differentiation and Airway Allergy

scientific article published on 16 January 2018

Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration

scientific article

HLA (A-B-C and -DRB1) alleles and brain MRI changes in multiple sclerosis: a longitudinal study

article

IL-18 is linked to raised IFN-gamma in multiple sclerosis and is induced by activated CD4(+) T cells via CD40-CD40 ligand interactions

scientific article published on 01 April 2002

IL-4 and retinoic acid synergistically induce regulatory dendritic cells expressing Aldh1a2.

scientific article published on 19 August 2013

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

scientific journal article

IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells

scholarly article

Immune deviation following pulse cyclophosphamide/methylprednisolone treatment of multiple sclerosis: Increased interleukin-4 production and associated eosinophilia

article

Immune modulation by Lacto-N-fucopentaose III in experimental autoimmune encephalomyelitis.

scientific article published on 30 December 2011

Immunopathogenesis of multiple sclerosis

Immunotherapy for neurological diseases

scientific article published on 04 June 2008

In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity

scientific article published on 02 September 2012

In vivo mechanisms of acquired thymic tolerance

scientific article published on 01 August 1997

Incidence and factors associated with treatment failure in the CLIMB multiple sclerosis cohort study.

scientific article published on 9 May 2009

Increased Th17 response to myelin peptides in pediatric MS.

scientific article published on 28 December 2012

Increased leptin and A-FABP levels in relapsing and progressive forms of MS

scientific article

Increased percentage of IL-12+ monocytes in the blood correlates with the presence of active MRI lesions in MS

scientific article published on 01 September 2001

Insights into the molecular pathogenesis of progression in multiple sclerosis: potential implications for future therapies

scientific article

Interferon-beta treatment alters peripheral blood monocytes chemokine production in MS patients

scientific article published on 01 May 2002

Kappa light chains in spinal fluid for diagnosing multiple sclerosis

scientific article published in The Journal of the American Medical Association

Kinin B1 receptor expression on multiple sclerosis mononuclear cells: correlation with magnetic resonance imaging T2-weighted lesion volume and clinical disability.

scientific article published in May 2005

Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis

scientific article

MECHANISMS OF INDIRECT ALLORECOGNITION

scientific article published on 01 April 1998

Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study

scientific article published on 28 December 2011

Mechanisms of oral tolerance by MHC peptides

scientific article published on February 1996

Medication Treatment in Multiple Sclerosis

Medulla Oblongata Volume: A Biomarker of Spinal Cord Damage and Disability in Multiple Sclerosis: Fig 1

scientific article published on 12 June 2008

Modulating co-stimulation

scientific article published on October 2007

Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice

scientific article

Multiple Sclerosis

Multiple sclerosis: what have we learned from magnetic resonance imaging studies?

scientific article published on March 1998

Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex

scientific article (publication date: 2004)

Myelin basic protein-reactive autoantibodies in the serum and cerebrospinal fluid of multiple sclerosis patients are characterized by low-affinity interactions

scientific article published on 01 March 2003

Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells.

scientific article published on June 2009

Neural stem cell biology may be well suited for improving brain tumor therapies.

scientific article

Neural stem cells and the future treatment of neurological diseases: raising the standard

scientific article

No sex-specific difference in disease trajectory in multiple sclerosis patients before and after age 50

scientific article

Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development

scientific article published on 3 August 2011

Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells

scientific article published on 12 April 2012

One year activity on subtraction MRI predicts subsequent 4 year activity and progression in multiple sclerosis

scientific article published on 22 March 2011

Oral administration of OKT3 monoclonal antibody to human subjects induces a dose-dependent immunologic effect in T cells and dendritic cells

scientific article published on 16 September 2009

Oral administration of myelin induces antigen-specific TGF-beta 1 secreting T cells in patients with multiple sclerosis

scientific article published in December 1997

Oral administration of myelin induces antigen-specific TGF-beta 1-secreting T cells in multiple sclerosis patients

scientific article published on April 1997

Oral salbutamol decreases IL-12 in patients with secondary progressive multiple sclerosis.

scientific article

Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, ⬇️

scientific article published on 01 November 1992

Paradoxical dysregulation of the neural stem cell pathway sonic hedgehog-Gli1 in autoimmune encephalomyelitis and multiple sclerosis

scientific article

Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing--remitting experimental autoimmune encephalomyelitis

scientific article published on 22 September 2007

Persistent inflammation alters the function of the endogenous brain stem cell compartment

scientific article published on 30 August 2008

Plasticity of Ly-6C(hi) myeloid cells in T cell regulation

scientific article

Population structure and HLA DRB1 1501 in the response of subjects with multiple sclerosis to first-line treatments

scientific article published on 27 November 2010

Potential application of tregitopes as immunomodulating agents in multiple sclerosis

scientific article published on 15 September 2011

Predicting clinical progression in multiple sclerosis with the magnetic resonance disease severity scale.

scientific article

Predicting short-term disability in multiple sclerosis

scientific article

Progressive Multiple Sclerosis

scientific article published on 06 July 2020

Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models.

scientific article

Pulse cyclophosphamide plus methylprednisolone induces myelin-antigen-specific IL-4-secreting T cells in multiple sclerosis patients

scientific article published on July 1998

Rate of brain atrophy in benign vs early multiple sclerosis.

scientific article

Regulatory functions of CD8+CD28– T cells in an autoimmune disease model

scientific article published in October 2003

Reversible neural stem cell niche dysfunction in a model of multiple sclerosis.

scientific article

Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells

scientific article

Role of costimulatory pathways in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis

scientific article published on November 2003

SARS-CoV-2 and Multiple Sclerosis: Not all immune depleting DMTs are equal or bad

scientific article published on 08 May 2020

Safety and Efficacy of Rituximab in Multiple Sclerosis: A Retrospective Observational Study

scientific article published on 12 November 2018

Serial blood T cell repertoire alterations in multiple sclerosis patients; correlation with clinical and MRI parameters

scientific article published on 27 June 2006

Serial magnetic resonance imaging in multiple sclerosis: correlation with attacks, disability, and disease stage

scientific article published on 01 May 2000

Sex influences in autoimmune disease

scientific article published on 9 August 2013

Smoking and disease progression in multiple sclerosis

scientific article published on July 2009

Stem cells: cross-talk and developmental programs

scientific article

Subventricular zone microglia transcriptional networks

scientific article

T cell costimulatory blockade as a novel immune intervention in autoimmune diseases

scientific article published on 01 September 2001

T cell costimulatory pathways: blockade for autoimmunity

scientific article

TGF-beta induces IL-9 production from human Th17 cells.

scientific article

Th17 and Treg balance in systemic sclerosis ⬇️

scientific article published on March 22, 2011

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

scientific article

The cell cycle associated protein, HTm4, is expressed in differentiating cells of the hematopoietic and central nervous system in mice

scientific journal article

The impact of lesion in-painting and registration methods on voxel-based morphometry in detecting regional cerebral gray matter atrophy in multiple sclerosis

scientific article

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

scientific article

The relationship between normal cerebral perfusion patterns and white matter lesion distribution in 1,249 patients with multiple sclerosis

scientific article published on 29 March 2011

The roles of the new negative T cell costimulatory pathways in regulating autoimmunity

scientific article published on May 2004

Therapeutic strategies in multiple sclerosis

scientific article published on 02 December 2011

Therapeutic strategies to prevent neurodegeneration and promote regeneration in multiple sclerosis.

scientific article

Three-year open protocol continuation study of oral tolerization with myelin antigens in multiple sclerosis and design of a phase III pivotal trial

scientific article published in February 1996

Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis.

scientific article published in July 2005

Type17 T-cells in central nervous system autoimmunity and tumors.

scientific article

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