List of works - Giuseppe Perugino

A comparative infrared spectroscopic study of glycoside hydrolases from extremophilic archaea revealed different molecular mechanisms of adaptation to high temperatures

scientific article published in June 2007

A novel fatty acid binding protein produced by teratocytes of the aphid parasitoid Aphidius ervi.

scientific article

A novel thermophilic glycosynthase that effects branching glycosylation

scientific article published in February 2000

A novel thermostable protein-tag: optimization of the Sulfolobus solfataricus DNA- alkyl-transferase by protein engineering

scientific article published on 23 October 2015

Activity and regulation of archaeal DNA alkyltransferase: conserved protein involved in repair of DNA alkylation damage

scientific article published on 13 December 2011

Activity of hyperthermophilic glycosynthases is significantly enhanced at acidic pH.

scientific article

An AGT-based protein-tag system for the labelling and surface immobilization of enzymes on E. coli outer membrane

scientific article published on 01 December 2019

Applications in Biocatalysis of Glycosyl Hydrolases from the Hyperthermophilic ArchaeonSulfolobus solfataricus

article published in 2003

Biochemical and Structural Studies of the Mycobacterium tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants

scientific article

Chromatin structure and dynamics in hot environments: architectural proteins and DNA topoisomerases of thermophilic archaea.

scientific article

Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA

scientific article

Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe.

scientific article published on 20 April 2018

Dissection of reverse gyrase activities: insight into the evolution of a thermostable molecular machine

scientific article published on 9 July 2008

Effects of Random Mutagenesis and In Vivo Selection on the Specificity and Stability of a Thermozyme

scientific article published in 2019

Engineering the stability and the activity of a glycoside hydrolase

scientific article published on 27 October 2010

Enzymatic Synthesis of 2-Deoxyglycosides Using the ß-Glycosidase of the Archaeon Sulfolobus solfataricus

Every OGT Is Illuminated … by Fluorescent and Synchrotron Lights.

scientific article published on 5 December 2017

Folding-upon-repair DNA nanoswitches for monitoring DNA repair enzymes activity

scientific article published on 08 January 2021

Folding‐upon‐Repair DNA Nanoswitches for Monitoring the Activity of DNA Repair Enzymes

scientific article

Genome stability: recent insights in the topoisomerase reverse gyrase and thermophilic DNA alkyltransferase

scientific article published on 08 August 2014

Glycosynthase-catalysed syntheses at pH below neutrality

scientific article published in November 2003

Highly productive autocondensation and transglycosylation reactions with Sulfolobus solfataricus glycosynthase

scientific article published in August 2005

In vivo and in vitro protein imaging in thermophilic archaea by exploiting a novel protein tag.

scientific article published on 3 October 2017

Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase.

scientific article

Isolation and characterization of a new family 42 beta-galactosidase from the thermoacidophilic bacterium Alicyclobacillus acidocaldarius: identification of the active site residues

scientific article

O6-alkylguanine-DNA Alkyltransferases in Microbes Living on the Edge: From Stability to Applicability

scientific article published on 20 April 2020

Oligosaccharide synthesis by glycosynthases

scientific article published on January 2004

Optimization of an In Vitro Transcription/Translation System Based on Cell Lysate

scientific article published on 11 February 2019

Positive supercoiling in thermophiles and mesophiles: of the good and evil.

scientific article

Probing the role of an invariant active site His in family GH1 β-glycosidases

Recent Advances in the Oligosaccharide Synthesis Promoted by Catalytically Engineered Glycosidases

scholarly article by Giuseppe Perugino et al published June 2005 in Advanced Synthesis & Catalysis

Restoration of the Activity of Active-Site Mutants of the Hyperthermophilic β-Glycosidase fromSulfolobus solfataricus: Dependence of the Mechanism on the Action of External Nucleophiles†

scientific article published on 01 December 1998

Reverse gyrase and genome stability in hyperthermophilic organisms

scientific article published on February 2009

Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors

scientific article

Structural, Kinetic, and Thermodynamic Analysis of Glucoimidazole-Derived Glycosidase Inhibitors†,‡

scientific article published on 01 October 2006

Structure and Properties of DNA Molecules Over The Full Range of Biologically Relevant Supercoiling States.

scientific article

Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein

scientific article

Synergic and opposing activities of thermophilic RecQ-like helicase and topoisomerase 3 proteins in Holliday junction processing and replication fork stabilization.

scientific article published on 21 June 2012

The DNA Alkylguanine DNA Alkyltransferase-2 (AGT-2) Of Caenorhabditis Elegans Is Involved In Meiosis And Early Development Under Physiological Conditions

scientific article published on 03 May 2019

The archaeal topoisomerase reverse gyrase is a helix-destabilizing protein that unwinds four-way DNA junctions

scientific article published on 17 September 2010

The reverse gyrase from Pyrobaculum calidifontis, a novel extremely thermophilic DNA topoisomerase endowed with DNA unwinding and annealing activities

scientific article published on 17 December 2013

Thermophilic glycosynthases for oligosaccharides synthesis

scientific article published in January 2012

Thermostability enhancement of the α-carbonic anhydrase from Sulfurihydrogenibium yellowstonense by using the anchoring-and-self-labelling-protein-tag system (ASL)

scientific article published on 01 December 2019

List of works by Giuseppe Perugino

A comparative infrared spectroscopic study of glycoside hydrolases from extremophilic archaea revealed different molecular mechanisms of adaptation to high temperatures

A novel fatty acid binding protein produced by teratocytes of the aphid parasitoid Aphidius ervi.

A novel thermophilic glycosynthase that effects branching glycosylation

A novel thermostable protein-tag: optimization of the Sulfolobus solfataricus DNA- alkyl-transferase by protein engineering

Activity and regulation of archaeal DNA alkyltransferase: conserved protein involved in repair of DNA alkylation damage

Activity of hyperthermophilic glycosynthases is significantly enhanced at acidic pH.

An AGT-based protein-tag system for the labelling and surface immobilization of enzymes on E. coli outer membrane

Applications in Biocatalysis of Glycosyl Hydrolases from the Hyperthermophilic ArchaeonSulfolobus solfataricus

Biochemical and Structural Studies of the Mycobacterium tuberculosis O6-Methylguanine Methyltransferase and Mutated Variants

Chromatin structure and dynamics in hot environments: architectural proteins and DNA topoisomerases of thermophilic archaea.

Crystal structure of Mycobacterium tuberculosis O6-methylguanine-DNA methyltransferase protein clusters assembled on to damaged DNA

Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe.

Dissection of reverse gyrase activities: insight into the evolution of a thermostable molecular machine

Effects of Random Mutagenesis and In Vivo Selection on the Specificity and Stability of a Thermozyme

Engineering the stability and the activity of a glycoside hydrolase

Enzymatic Synthesis of 2-Deoxyglycosides Using the ß-Glycosidase of the Archaeon Sulfolobus solfataricus

Every OGT Is Illuminated … by Fluorescent and Synchrotron Lights.

Folding-upon-repair DNA nanoswitches for monitoring DNA repair enzymes activity

Folding‐upon‐Repair DNA Nanoswitches for Monitoring the Activity of DNA Repair Enzymes

Genome stability: recent insights in the topoisomerase reverse gyrase and thermophilic DNA alkyltransferase

Glycosynthase-catalysed syntheses at pH below neutrality

Highly productive autocondensation and transglycosylation reactions with Sulfolobus solfataricus glycosynthase

In vivo and in vitro protein imaging in thermophilic archaea by exploiting a novel protein tag.

Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase.

Isolation and characterization of a new family 42 beta-galactosidase from the thermoacidophilic bacterium Alicyclobacillus acidocaldarius: identification of the active site residues

O6-alkylguanine-DNA Alkyltransferases in Microbes Living on the Edge: From Stability to Applicability

Oligosaccharide synthesis by glycosynthases

Optimization of an In Vitro Transcription/Translation System Based on Cell Lysate

Positive supercoiling in thermophiles and mesophiles: of the good and evil.

Probing the role of an invariant active site His in family GH1 β-glycosidases

Recent Advances in the Oligosaccharide Synthesis Promoted by Catalytically Engineered Glycosidases

Restoration of the Activity of Active-Site Mutants of the Hyperthermophilic β-Glycosidase fromSulfolobus solfataricus: Dependence of the Mechanism on the Action of External Nucleophiles†

Reverse gyrase and genome stability in hyperthermophilic organisms

Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors

Structural, Kinetic, and Thermodynamic Analysis of Glucoimidazole-Derived Glycosidase Inhibitors†,‡

Structure and Properties of DNA Molecules Over The Full Range of Biologically Relevant Supercoiling States.

Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein

Synergic and opposing activities of thermophilic RecQ-like helicase and topoisomerase 3 proteins in Holliday junction processing and replication fork stabilization.

The DNA Alkylguanine DNA Alkyltransferase-2 (AGT-2) Of Caenorhabditis Elegans Is Involved In Meiosis And Early Development Under Physiological Conditions

The archaeal topoisomerase reverse gyrase is a helix-destabilizing protein that unwinds four-way DNA junctions

The reverse gyrase from Pyrobaculum calidifontis, a novel extremely thermophilic DNA topoisomerase endowed with DNA unwinding and annealing activities

Thermophilic glycosynthases for oligosaccharides synthesis

Thermostability enhancement of the α-carbonic anhydrase from Sulfurihydrogenibium yellowstonense by using the anchoring-and-self-labelling-protein-tag system (ASL)