List of works - Anders Albrechtsen

A -243A-->G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects.

scientific article

A Bayesian multilocus association method: allowing for higher-order interaction in association studies

scientific article published on 15 April 2007

A common Greenlandic Inuit BRCA1 RING domain founder mutation

scientific article published on 26 May 2008

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

scientific article

A genomic history of Aboriginal Australia

scientific article (publication date: 21 September 2016)

A likelihood method for estimating present-day human contamination in ancient DNA samples using low-depth haploid chromosome data

article

A likelihood method for estimating present-day human contamination in ancient male samples using low-depth X-chromosome data

scientific article published on 01 February 2020

A method for detecting IBD regions simultaneously in multiple individuals--with applications to disease genetics

scientific article

A novel -192c/g mutation in the proximal P2 promoter of the hepatocyte nuclear factor-4 alpha gene (HNF4A) associates with late-onset diabetes

scientific article published in June 2006

A reference‐free approach to analyse RADseq data using standard next generation sequencing toolkits

scientific article published in 2021

A southern African origin and cryptic structure in the highly mobile plains zebra

scientific article published in 2018

A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads

scientific article

ANGSD: Analysis of Next Generation Sequencing Data.

scientific article

Allele frequency-free inference of close familial relationships from genotypes or low depth sequencing data

Allele frequency-free inference of close familial relationships from genotypes or low-depth sequencing data

scientific article published on 01 January 2019

An Aboriginal Australian genome reveals separate human dispersals into Asia

scientific article (publication date: 7 October 2011)

Ancestry-specific association mapping in admixed populations

scientific article published on 18 March 2019

Ancient genomes revisit the ancestry of domestic and Przewalski's horses

scientific article published on 22 February 2018

Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers

scientific article published on 5 October 2017

Ancient genomic changes associated with domestication of the horse

scientific article

Ancient human genome sequence of an extinct Palaeo-Eskimo

scientific article

Archaic Adaptive Introgression in TBX15/WARS2.

scientific article

Ascertainment biases in SNP chips affect measures of population divergence

scientific article

Association Testing for Next‐Generation Sequencing Data Using Score Statistics ⬇️

scientific article published on May 8, 2012

Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged D

article by Niels Grarup et al published September 2008 in Diabetes

Calculation of Tajima's D and other neutrality test statistics from low depth next-generation sequencing data.

scientific article

Combined analyses of 20 common obesity susceptibility variants ⬇️

scientific article

Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene–gene interaction

article

DamMet: ancient methylome mapping accounting for errors, true variants, and post-mortem DNA damage

article by Kristian Ebbesen Hanghøj et al published 1 April 2019 in GigaScience

Darwinian and demographic forces affecting human protein coding genes

scientific article published on 11 March 2009

Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing

scientific article published on 01 November 2019

Diabetes in Population Isolates: Lessons from Greenland

scientific article published on September 2015

Erratum: The origin and evolution of maize in the Southwestern United States

scholarly article published in Nature Plants

Estimating inbreeding coefficients from NGS data: Impact on genotype calling and allele frequency estimation

scientific article

Estimating individual admixture proportions from next generation sequencing data

scientific article

Estimating narrow-sense heritability using family data from admixed populations

scientific article published on 09 April 2020

Estimation of allele frequency and association mapping using next-generation sequencing data

scientific article

Evolutionary Genomics and Conservation of the Endangered Przewalski's Horse

scientific article published on 22 September 2015

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.

scientific article published on 19 November 2012

Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity

scientific article

Founder Effect of the RETC611Y Mutation in Multiple Endocrine Neoplasia 2A in Denmark: A Nationwide Study

scientific article published on 12 October 2017

Functional SOCS1 polymorphisms are associated with variation in obesity in whites.

scientific article published in March 2009

GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal

scientific article published on 30 October 2023

Genetic analysis of the estrogen-related receptor α and studies of association with obesity and type 2 diabetes

article

Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis

Genetic architecture of obesity and related metabolic traits — recent insights from isolated populations

article by Mette Korre Andersen et al published June 2018 in Current Opinion in Genetics & Development

Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets

scientific article

Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population

scientific article published on 26 February 2018

Genetic screening of the FLCN gene identify six novel variants and a Danish founder mutation

scientific article published on 13 October 2016

Genetic study of the Arctic CPT1A variant suggests that its effect on fatty acid levels is modulated by traditional Inuit diet

scientific article published on 19 June 2020

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

scientific article published on 6 September 2009

Genetics of Type 2 Diabetes: the Power of Isolated Populations

scientific article

Genome-Wide Association Study of Genetic Variants in LPS-Stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α Cytokine Response in a Danish Cohort

scientific article

Genomic Analyses from Non-invasive Prenatal Testing Reveal Genetic Associations, Patterns of Viral Infections, and Chinese Population History

Genomic diversity and novel genome-wide association with fruit morphology in Capsicum, from 746k polymorphic sites

scientific article published on 11 July 2019

Genomic evidence for the Pleistocene and recent population history of Native Americans

scientific article

Genotype and SNP calling from next-generation sequencing data

scientific article

Greenlandic Inuit show genetic signatures of diet and climate adaptation

scientific article

High genetic diversity and low differentiation reflect the ecological versatility of the African leopard

scientific article published in 2021

Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders

scientific article published on 24 June 2016

Identification of a novel BRCA1 nucleotide 4803delCC/c.4684delCC mutation and a nucleotide 249T>A/c.130T>A (p.Cys44Ser) mutation in two Greenlandic Inuit families: implications for genetic screening of Greenlandic Inuit families with high risk for br

Identification of a novel locus for a USH3 like syndrome combined with congenital cataract

scientific article published in October 2010

Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation

scientific article published on 21 June 2008

Inferring Population Structure and Admixture Proportions in Low Depth NGS Data

Inferring Population Structure and Admixture Proportions in Low-Depth NGS Data

article

Interleukin-6 autoantibodies are involved in the pathogenesis of a subset of type 2 diabetes

scientific article published on 16 December 2009

Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovarian cancer families

scientific article published on 12 June 2008

Large-scale study of the ?232C�>�G polymorphism of PCK1 in Type�2 diabetes

Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic

scientific article published on 20 April 2022

Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

scientific article

Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation

scientific article published on 17 October 2007

Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome.

scientific article

Natural selection and the distribution of identity-by-descent in the human genome

scientific article

Next-generation biology: Sequencing and data analysis approaches for non-model organisms

scientific article

Novel de novo BRCA2 mutation in a patient with a family history of breast cancer

scientific article

Partial USH2A deletions contribute to Usher syndrome in Denmark

scientific article published on 25 March 2015

Population genomics of the Viking world

scientific article published on 16 September 2020

Powerful Inference with the D-Statistic on Low-Coverage Whole-Genome Data

scientific article published in December 2017

Prehistoric genomes reveal the genetic foundation and cost of horse domestication

scientific article

Quantifying population genetic differentiation from next-generation sequencing data

scientific article

Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse

scientific article

RelateAdmix: a software tool for estimating relatedness between admixed individuals

scientific article

Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium

scientific article

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

SNP calling, genotype calling, and sample allele frequency estimation from New-Generation Sequencing data

scientific article (publication date: 2012)

Segregation distortion in chicken and the evolutionary consequences of female meiotic drive in birds

scientific article published on 27 January 2010

Speciation with gene flow in equids despite extensive chromosomal plasticity

scientific article

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies

scientific article published on 7 September 2007

Studies of associations between the Arg389Gly polymorphism of the beta1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects.

scientific article

Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes.

scientific article

Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects

scientific article published on 31 October 2006

Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects

scientific article published on 25 July 2006

Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans.

scientific article

Testing for Hardy-Weinberg equilibrium in structured populations using genotype or low-depth next generation sequencing data

scientific article published on 12 June 2019

The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects.

scientific article published on 25 March 2008

The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation: Insights from the Greenlandic Inuit

scientific article published on 30 November 2016

The ancestry and affiliations of Kennewick Man

scientific article

The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders

scientific article published on 24 January 2020

The genetic prehistory of the New World Arctic

scientific article

The genome of a Late Pleistocene human from a Clovis burial site in western Montana

scientific article

The origin and evolution of maize in the American Southwest

The origin and evolution of maize in the Southwestern United States

scientific article

The validation and assessment of machine learning: a game of prediction from high-dimensional data

scientific article

Uncovering the genetic history of the present-day Greenlandic population. ⬇️

scientific article

Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans

scientific article

Variants in the 5′ region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects

article

Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population

scientific article published on 22 January 2014

Variation in the peroxisome proliferator-activated receptor delta gene in relation to common metabolic traits in 7,495 middle-aged white people

scientific article published on 13 April 2007

Weighting sequence variants based on their annotation increases power of whole-genome association studies

scientific article published on 8 February 2016

Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes

scientific article

fastNGSadmix: admixture proportions and principal component analysis of a single NGS sample

scientific article published in October 2017

List of works by Anders Albrechtsen

A -243A-->G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects.

A Bayesian multilocus association method: allowing for higher-order interaction in association studies

A common Greenlandic Inuit BRCA1 RING domain founder mutation

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

A genomic history of Aboriginal Australia

A likelihood method for estimating present-day human contamination in ancient DNA samples using low-depth haploid chromosome data

A likelihood method for estimating present-day human contamination in ancient male samples using low-depth X-chromosome data

A method for detecting IBD regions simultaneously in multiple individuals--with applications to disease genetics

A novel -192c/g mutation in the proximal P2 promoter of the hepatocyte nuclear factor-4 alpha gene (HNF4A) associates with late-onset diabetes

A reference‐free approach to analyse RADseq data using standard next generation sequencing toolkits

A southern African origin and cryptic structure in the highly mobile plains zebra

A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads

ANGSD: Analysis of Next Generation Sequencing Data.

Allele frequency-free inference of close familial relationships from genotypes or low depth sequencing data

Allele frequency-free inference of close familial relationships from genotypes or low-depth sequencing data

An Aboriginal Australian genome reveals separate human dispersals into Asia

Ancestry-specific association mapping in admixed populations

Ancient genomes revisit the ancestry of domestic and Przewalski's horses

Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers

Ancient genomic changes associated with domestication of the horse

Ancient human genome sequence of an extinct Palaeo-Eskimo

Archaic Adaptive Introgression in TBX15/WARS2.

Ascertainment biases in SNP chips affect measures of population divergence

Association Testing for Next‐Generation Sequencing Data Using Score Statistics ⬇️

Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged D

Calculation of Tajima's D and other neutrality test statistics from low depth next-generation sequencing data.

Combined analyses of 20 common obesity susceptibility variants ⬇️

Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene–gene interaction

DamMet: ancient methylome mapping accounting for errors, true variants, and post-mortem DNA damage

Darwinian and demographic forces affecting human protein coding genes

Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing

Diabetes in Population Isolates: Lessons from Greenland

Erratum: The origin and evolution of maize in the Southwestern United States

Estimating inbreeding coefficients from NGS data: Impact on genotype calling and allele frequency estimation

Estimating individual admixture proportions from next generation sequencing data

Estimating narrow-sense heritability using family data from admixed populations

Estimation of allele frequency and association mapping using next-generation sequencing data

Evolutionary Genomics and Conservation of the Endangered Przewalski's Horse

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.

Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity

Founder Effect of the RETC611Y Mutation in Multiple Endocrine Neoplasia 2A in Denmark: A Nationwide Study

Functional SOCS1 polymorphisms are associated with variation in obesity in whites.

GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal

Genetic analysis of the estrogen-related receptor α and studies of association with obesity and type 2 diabetes

Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis

Genetic architecture of obesity and related metabolic traits — recent insights from isolated populations

Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets

Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population

Genetic screening of the FLCN gene identify six novel variants and a Danish founder mutation

Genetic study of the Arctic CPT1A variant suggests that its effect on fatty acid levels is modulated by traditional Inuit diet

Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

Genetics of Type 2 Diabetes: the Power of Isolated Populations

Genome-Wide Association Study of Genetic Variants in LPS-Stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α Cytokine Response in a Danish Cohort

Genomic Analyses from Non-invasive Prenatal Testing Reveal Genetic Associations, Patterns of Viral Infections, and Chinese Population History

Genomic diversity and novel genome-wide association with fruit morphology in Capsicum, from 746k polymorphic sites

Genomic evidence for the Pleistocene and recent population history of Native Americans

Genotype and SNP calling from next-generation sequencing data

Greenlandic Inuit show genetic signatures of diet and climate adaptation

High genetic diversity and low differentiation reflect the ecological versatility of the African leopard

Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders

Identification of a novel BRCA1 nucleotide 4803delCC/c.4684delCC mutation and a nucleotide 249T>A/c.130T>A (p.Cys44Ser) mutation in two Greenlandic Inuit families: implications for genetic screening of Greenlandic Inuit families with high risk for br

Identification of a novel locus for a USH3 like syndrome combined with congenital cataract

Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation

Inferring Population Structure and Admixture Proportions in Low Depth NGS Data

Inferring Population Structure and Admixture Proportions in Low-Depth NGS Data

Interleukin-6 autoantibodies are involved in the pathogenesis of a subset of type 2 diabetes

Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovarian cancer families

Large-scale study of the ?232C�>�G polymorphism of PCK1 in Type�2 diabetes

Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic

Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation

Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome.

Natural selection and the distribution of identity-by-descent in the human genome

Next-generation biology: Sequencing and data analysis approaches for non-model organisms

Novel de novo BRCA2 mutation in a patient with a family history of breast cancer

Partial USH2A deletions contribute to Usher syndrome in Denmark

Population genomics of the Viking world

Powerful Inference with the D-Statistic on Low-Coverage Whole-Genome Data