List of works - Jeffrey Barrett

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

scientific article

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

scientific article

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

scientific article

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

scientific article (publication date: June 2007)

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

scientific article

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

scientific article

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

scientific article

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

scientific article (publication date: July 2007)

Guidelines for investigating causality of sequence variants in human disease

scientific article

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

scientific article published on 20 July 2015

Common deletion polymorphisms in the human genome

scientific article

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

Multiple common variants for celiac disease influencing immune gene expression

scientific article

A reference panel of 64,976 haplotypes for genotype imputation

scientific article

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

scientific article published on 29 September 2013

The UK10K project identifies rare variants in health and disease

scientific article

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

scientific article

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

scientific article

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

scientific article

Common variants at five new loci associated with early-onset inflammatory bowel disease

scientific article

Genetic diagnosis of developmental disorders in the DDD study: a scalable analysis of genome-wide research data

scientific article

Pervasive sharing of genetic effects in autoimmune disease

scientific article

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

scientific article

Evaluating coverage of genome-wide association studies

scientific article published on 21 May 2006

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

scientific article published on 27 April 2008

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

scientific article

Haploview: Visualization and analysis of SNP genotype data

scientific article

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

scientific article

Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage

scientific article

Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1.

scientific article

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.

scientific article published on 9 January 2017

Distribution and medical impact of loss-of-function variants in the Finnish founder population

scientific article

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

scientific article

A genome-wide association study of anorexia nervosa

scientific article

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.

scientific article

Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis

scientific article

Fine-mapping inflammatory bowel disease loci to single-variant resolution

scientific article

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

scientific article

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

scientific article

Genetic risk prediction in complex disease

scientific article

Open Targets: a platform for therapeutic target identification and validation

scientific article

Class II HLA interactions modulate genetic risk for multiple sclerosis

scientific article published on 07 September 2015

Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship

scientific article

Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing.

scientific article published in August 2016

An integrated haplotype map of the human major histocompatibility complex

scientific article

Making new genetic diagnoses with old data: iterative reanalysis and reporting from genome-wide data in 1,133 families with developmental disorders

scientific article published on 11 January 2018

Synthetic associations are unlikely to account for many common disease genome-wide association signals

scientific article

Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration

scientific article published on 16 March 2015

Evaluating the effects of imputation on the power, coverage, and cost efficiency of genome-wide SNP platforms

scientific article published on 26 June 2008

List of works by Jeffrey Barrett

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

Guidelines for investigating causality of sequence variants in human disease

Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

Common deletion polymorphisms in the human genome

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

Multiple common variants for celiac disease influencing immune gene expression

A reference panel of 64,976 haplotypes for genotype imputation

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

The UK10K project identifies rare variants in health and disease

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

Common variants at five new loci associated with early-onset inflammatory bowel disease

Genetic diagnosis of developmental disorders in the DDD study: a scalable analysis of genome-wide research data

Pervasive sharing of genetic effects in autoimmune disease

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

Evaluating coverage of genome-wide association studies

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

Haploview: Visualization and analysis of SNP genotype data

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage

Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1.

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.

Distribution and medical impact of loss-of-function variants in the Finnish founder population

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

A genome-wide association study of anorexia nervosa

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.

Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis

Fine-mapping inflammatory bowel disease loci to single-variant resolution

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

Genetic risk prediction in complex disease

Open Targets: a platform for therapeutic target identification and validation

Class II HLA interactions modulate genetic risk for multiple sclerosis

Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship

Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing.

An integrated haplotype map of the human major histocompatibility complex

Making new genetic diagnoses with old data: iterative reanalysis and reporting from genome-wide data in 1,133 families with developmental disorders

Synthetic associations are unlikely to account for many common disease genome-wide association signals

Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration

Evaluating the effects of imputation on the power, coverage, and cost efficiency of genome-wide SNP platforms