List of works - Matthew A. Brown

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

scientific article

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article

Five years of GWAS discovery

scientific article

Genetics of rheumatoid arthritis contributes to biology and drug discovery

scientific article

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

scientific article

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

scientific article published in October 2013

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

scientific article

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

scientific article

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

scientific article

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

scientific article

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

scientific article

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

scientific article published on June 9, 2013

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

scientific article published on 10 January 2010

Promise and pitfalls of the Immunochip

scientific article published on February 2011

Genetic insights into common pathways and complex relationships among immune-mediated diseases

scientific article published on 06 August 2013

Susceptibility to ankylosing spondylitis in twins the role of genes, HLA, and the environment

article

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

scientific article

Bayesian refinement of association signals for 14 loci in 3 common diseases

scientific article published on 28 October 2012

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci

scientific article

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

scientific article

Efficacy and safety of adalimumab in patients with non-radiographic axial spondyloarthritis: results of a randomised placebo-controlled trial (ABILITY-1).

scientific article published on 7 July 2012

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

scientific article

Common variants at 12q14 and 12q24 are associated with hippocampal volume

scientific article

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

scientific article

Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer

scientific article

Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk

scientific article

A review of the MHC genetics of rheumatoid arthritis.

scientific article published on May 2004

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

scientific article published in July 2012

Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming

scientific article

Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans

scientific article

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Brief Report: Intestinal Dysbiosis in Ankylosing Spondylitis

scientific article published on 21 November 2014

Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

scientific article

Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease

scientific article

HLA class I associations of ankylosing spondylitis in the white population in the United Kingdom.

scientific article published on 01 April 1996

Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci

scientific article

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis

scientific article published on January 2014

β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice

article

Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom

article

Genome-wide association study to identify genetic determinants of severe asthma.

scientific article

Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1.

scientific article published on 21 May 2015

Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype

scientific article

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density

scientific article

Genetics of ankylosing spondylitis--insights into pathogenesis

scientific article published on 06 October 2015

Association ofERAP1, but notIL23R, with ankylosing spondylitis in a Han Chinese population

article

Common variants in the region around Osterix are associated with bone mineral density and growth in childhood

scientific article published on 30 January 2009

Investigating the genetic association between ERAP1 and ankylosing spondylitis

scientific article published on 18 August 2009

Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations

scientific article

List of works by Matthew A. Brown

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Five years of GWAS discovery

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

Promise and pitfalls of the Immunochip

Genetic insights into common pathways and complex relationships among immune-mediated diseases

Susceptibility to ankylosing spondylitis in twins the role of genes, HLA, and the environment

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

Bayesian refinement of association signals for 14 loci in 3 common diseases

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

Efficacy and safety of adalimumab in patients with non-radiographic axial spondyloarthritis: results of a randomised placebo-controlled trial (ABILITY-1).

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

Common variants at 12q14 and 12q24 are associated with hippocampal volume

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer

Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk

A review of the MHC genetics of rheumatoid arthritis.

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming

Defects in the IFT-B component IFT172 cause Jeune and Mainzer-Saldino syndromes in humans

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Brief Report: Intestinal Dysbiosis in Ankylosing Spondylitis

Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease

HLA class I associations of ankylosing spondylitis in the white population in the United Kingdom.

Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis

β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice

Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom

Genome-wide association study to identify genetic determinants of severe asthma.

Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1.

Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density

Genetics of ankylosing spondylitis--insights into pathogenesis

Association ofERAP1, but notIL23R, with ankylosing spondylitis in a Han Chinese population

Common variants in the region around Osterix are associated with bone mineral density and growth in childhood

Investigating the genetic association between ERAP1 and ankylosing spondylitis

Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations