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List of works by Renato V. Iozzo

A central function for perlecan in skeletal muscle and cardiovascular development

scientific article

A central role for decorin during vertebrate convergent extension

scientific article published on 10 February 2009

A composite element binding the vitamin D receptor and the retinoic X receptor alpha mediates the transforming growth factor-beta inhibition of decorin gene expression in articular chondrocytes

scientific article published on 13 June 2001

A current view of perlecan in physiology and pathology: A mosaic of functions

scientific article

A decorin-deficient matrix affects skin chondroitin/dermatan sulfate levels and keratinocyte function.

scientific article published on 18 January 2014

A giant of matrix biology: a celebration of Dick Heinegård's life

scientific article

A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis.

scientific article

A mouse model of spontaneous preterm birth based on the genetic ablation of biglycan and decorin

scientific article

A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia

scientific article

A novel interaction between perlecan protein core and progranulin: potential effects on tumor growth

scientific article

A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival.

scientific article published on July 2005

A role for decorin in a murine model of allergen-induced asthma

scientific article published on 04 March 2011

A role for decorin in controlling proliferation, adhesion, and migration of murine embryonic fibroblasts

scientific article

A role for decorin in cutaneous wound healing and angiogenesis.

scientific article published in July 2006

A role for decorin in the remodeling of myocardial infarction.

scientific article published in June 2005

A role for the perlecan protein core in the activation of the keratinocyte growth factor receptor

scientific article published on October 2001

Ablation of the decorin gene enhances experimental hepatic fibrosis and impairs hepatic healing in mice.

scientific article published on 18 October 2010

Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction

scientific article published on March 2002

Achilles tendons from decorin- and biglycan-null mouse models have inferior mechanical and structural properties predicted by an image-based empirical damage model

scientific article published on 31 March 2015

Activation of extracellular signal-regulated protein kinase1,2 results in down-regulation of decorin expression in fibroblasts

scientific article published on July 2000

Alterations in lung mechanics in decorin-deficient mice

scientific article published on 24 September 2004

Altered glycosaminoglycan composition in reactive and neoplastic human liver

article

Altered methylation of versican proteoglycan gene in human colon carcinoma

scientific article published in September 1990

Altered proteoglycan gene expression and the tumor stroma

scientific article

An Anti-oncogenic Role for Decorin

scientific article published in Journal of Biological Chemistry

An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis

scientific article

An antimetastatic role for decorin in breast cancer.

scientific article published on 7 August 2008

Analysis of proteoglycans by high-performance liquid chromatography: A rapid micromethod for the separation of proteoglycans from tissue and cell culture

article

Anatomic and hemodynamic effects of catheter-delivered ablation energies in the ventricle

scientific article published on 01 August 1985

Androgen receptor expression induces FGF2, FGF-binding protein production, and FGF2 release in prostate carcinoma cells: role of FGF2 in growth, survival, and androgen receptor down-modulation

scientific article published on December 2002

Angiogenesis in collagen I requires alpha2beta1 ligation of a GFP*GER sequence and possibly p38 MAPK activation and focal adhesion disassembly

scientific article

Angiostatic cues from the matrix: endothelial cell autophagy meets hyaluronan biology

scientific article published on 05 October 2020

Autophagic degradation of HAS2 in endothelial cells: A novel mechanism to regulate angiogenesis

scientific article published on 19 February 2020

Autophagic tumor stroma: A biofuel for cancer growth

scientific article published on 01 October 2011

BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan

scientific article

Basement membrane proteoglycans: from cellar to ceiling

scientific article

Basement membrane proteoglycans: modulators Par Excellence of cancer growth and angiogenesis.

scientific article published on 15 May 2009

Biglycan and decorin differentially regulate signaling in the fetal membranes

scientific article

Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury

scientific article published on 31 January 2019

Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury.

scientific article

Bimodal role of NADPH oxidases in the regulation of biglycan-triggered IL-1β synthesis.

scientific article published on 12 December 2015

Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction.

scientific article published on 6 May 2008

Biological interplay between proteoglycans and their innate immune receptors in inflammation

scientific article

Biologically active decorin is a monomer in solution.

scientific article published on 3 December 2003

Caspase-3 activation triggers extracellular cathepsin L release and endorepellin proteolysis

scientific article

Catabolic degradation of endothelial VEGFA via autophagy

scientific article published on 24 March 2020

Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts

scientific article

Cell surface heparan sulfate proteoglycan and the neoplastic phenotype

scientific article

Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer.

scientific article

Cerebral infarction complicating umbilical vein catheterization

scientific article published on 01 July 1979

Characterization of the complete genomic structure of the human WNT-5A gene, functional analysis of its promoter, chromosomal mapping, and expression in early human embryogenesis

scientific article (publication date: 29 December 1995)

Chondroitin sulfate proteoglycan is a constituent of the basement membrane in the rat embryo parietal yolk sac.

scientific article published in January 1987

Collagen fibril organization in the pregnant endometrium of decorin-deficient mice.

scientific article published on 9 November 2009

Collagen matrix influences the morphologic features and steroid secretion of human granulosa cells

scientific article published on 01 December 1988

Compensatory fetal membrane mechanisms between biglycan and decorin in inflammation.

scientific article published on 23 April 2015

Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis

scientific article

Cosmetics for the matrix: An attractive new style for Matrix Biology

scientific article published on 04 March 2015

De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways

scientific article published on 18 December 2013

Decoding the Matrix: Instructive Roles of Proteoglycan Receptors

scientific article

Decorin Activates the Epidermal Growth Factor Receptor and Elevates Cytosolic Ca2+in A431 Carcinoma Cells

scientific article published in Journal of Biological Chemistry

Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells

scientific article

Decorin antagonizes IGF receptor I (IGF-IR) function by interfering with IGF-IR activity and attenuating downstream signaling

scientific article

Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels

scientific article

Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.

scientific article published on 22 December 2011

Decorin as a multivalent therapeutic agent against cancer.

scientific article published on 29 October 2015

Decorin binds near the C terminus of type I collagen

scientific article

Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope

scientific article (publication date: 20 September 2002)

Decorin causes autophagy in endothelial cells via Peg3

scientific article

Decorin deficiency enhances progressive nephropathy in diabetic mice.

scientific article

Decorin deficiency leads to impaired angiogenesis in injured mouse cornea.

scientific article published on 28 October 2004

Decorin deficiency promotes epithelial-mesenchymal transition and colon cancer metastasis

scientific article published on 13 October 2020

Decorin deficiency promotes hepatic carcinogenesis

scientific article

Decorin differentially modulates the activity of insulin receptor isoform A ligands.

scientific article

Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis

scientific article published on July 2005

Decorin expression is important for age-related changes in tendon structure and mechanical properties.

scientific article published on 23 November 2012

Decorin has an appetite for endothelial cell autophagy

scientific article published on 13 August 2013

Decorin induces mitophagy in breast carcinoma cells via peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitostatin

scientific article

Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1.

scientific article published on 15 February 2013

Decorin interacting network: A comprehensive analysis of decorin-binding partners and their versatile functions.

scientific article

Decorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis.

scientific article published on 25 March 2013

Decorin is a biological ligand for the epidermal growth factor receptor

scientific article

Decorin is a devouring proteoglycan: Remodeling of intracellular catabolism via autophagy and mitophagy

scientific article published on 25 October 2017

Decorin is a novel antagonistic ligand of the Met receptor

scientific article published on 11 May 2009

Decorin is an autophagy-inducible proteoglycan and is required for proper in vivo autophagy

scientific article

Decorin potentiates interferon-γ activity in a model of allergic inflammation

scientific article published on 4 March 2013

Decorin prevents metastatic spreading of breast cancer.

scientific article published on February 2005

Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model

scientific article

Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation

scientific article published on 11 July 2006

Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development

scientific article

Decorin suppresses tumor cell-mediated angiogenesis

scientific article published on 01 July 2002

Decorin, a novel player in the insulin-like growth factor system.

scientific article published on 8 February 2005

Decorin, epiphycan, and lumican genes are closely linked on murine Chromosome 10 and are deleted in lethal steel mutants

article

Decorin-TGFβ axis in hepatic fibrosis and cirrhosis

scientific article

Decorin-evoked paternally expressed gene 3 (PEG3) is an upstream regulator of the transcription factor EB (TFEB) in endothelial cell autophagy.

scientific article published on 10 August 2017

Decorin-induced Growth Suppression Is Associated with Up-regulation of p21, an Inhibitor of Cyclin-dependent Kinases

scientific article published in Journal of Biological Chemistry

Decorin-inducible Peg3 Evokes Beclin 1-mediated Autophagy and Thrombospondin 1-mediated Angiostasis

scientific article published on 07 February 2017

Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in mice

scientific article published on 8 December 2011

Decorin-transforming growth factor- interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices

scientific article published on 17 October 2007

Decorin: a guardian from the matrix

scientific article

Deficiency of decorin induces expression of Foxp3 in CD4⁺CD25⁺ T cells in a murine model of allergic asthma

scientific article published on 25 February 2015

Developmental expression of perlecan during murine embryogenesis ⬇️

scientific article published on October 1, 1997

Dichotomy of decorin activity on the insulin-like growth factor-I system

scientific article published on 15 February 2013

Dissecting the role of hyaluronan synthases in the tumor microenvironment

scientific article published on 22 April 2019

Diverse cell signaling events modulated by perlecan.

scientific article published on October 2008

Early diagnosis of experimental necrotizing enterocolitis using proton nuclear magnetic resonance

scientific article

Ectopic expression of A-myb in transgenic mice causes follicular hyperplasia and enhanced B lymphocyte proliferation.

scientific article

Effect of PEEP on induced constriction is enhanced in decorin-deficient mice

scientific article published on 17 August 2007

Effect of altered matrix proteins on quasilinear viscoelastic properties in transgenic mouse tail tendons

scientific article published on May 2003

Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear fact

scientific article

Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin.

scientific article

Endorepellin evokes an angiostatic stress signaling cascade in endothelial cells

scientific article published on 23 March 2020

Endorepellin evokes autophagy in endothelial cells

scientific article

Endorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cells

scientific article

Endorepellin remodels the endothelial transcriptome toward a pro-autophagic and pro-mitophagic gene signature

scientific article published on 19 June 2018

Endorepellin, a novel inhibitor of angiogenesis derived from the C terminus of perlecan

scientific article (publication date: 7 February 2003)

Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism

scientific article

Endorepellin-evoked Autophagy Contributes to Angiostasis.

scientific article published on 19 July 2016

Endostatin and endorepellin: A common route of action for similar angiostatic cancer avengers

scientific article published on 27 October 2015

Endothelial cells provide feedback control for vascular remodeling through a mechanosensitive autocrine TGF-beta signaling pathway

scientific article

EphA2 is a functional receptor for the growth factor progranulin.

scientific article

Estrogen treatment changes the cellular distribution of apolipoprotein E in the liver

scientific article published on 01 September 1982

Evidence of a small hydrophobic domain in the core protein of the heparan sulfate proteoglycan from human colon carcinoma cells

scientific article published on 01 October 1986

Experimental Myocardial Cryoinjury: Local Electromechanical Changes, Arrhythmogenicity, and Methods for Determining Depth of Injury

scientific article published on 01 July 1987

Expression pattern and mapping of the murine versican gene (Cspg2) to chromosome 13.

scientific article

Extracellular matrix proteoglycans control the fate of bone marrow stromal cells.

scientific article published on 17 June 2005

Extracellular matrix: The driving force of mammalian diseases

scientific article published on 3 April 2018

FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney

scientific article

Fez1/Lzts1-deficient mice are more susceptible to N-butyl-N-(4-hydroxybutil) nitrosamine (BBN) carcinogenesis

scientific article published on 12 January 2008

Fibroblast growth factor-2.

scientific article

Fibroblast growth factor-binding protein is a novel partner for perlecan protein core

scientific article (publication date: 30 March 2001)

Forced exercise-induced osteoarthritis is attenuated in mice lacking the small leucine-rich proteoglycan decorin

scientific article published on 4 July 2016

Formation of nodular structures resembling mature articular cartilage in long–term primary cultures of human fetal epiphyseal chondrocytes on a hydrogel substrate

article

Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation

scientific article

Genetic evidence for key roles of decorin and biglycan in dentin mineralization.

scientific article published on 12 February 2009

Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan

scientific article published on 09 January 2009

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation

scientific article published on 24 August 2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

Heparan sulfate proteoglycan of human colon: partial molecular cloning, cellular expression, and mapping of the gene (HSPG2) to the short arm of human chromosome 1.

scientific article published in July 1991

Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena

scientific article

Heparan sulfate proteoglycans: intricate molecules with intriguing functions.

scientific article

Heparan sulfate-dependent signaling of fibroblast growth factor 18 by chondrocyte-derived perlecan.

scientific article

Heparanase: multiple functions in inflammation, diabetes and atherosclerosis

scientific article published on 07 March 2013

Heparin and endothelial cell growth factor modulate collagen and proteoglycan production in human smooth muscle cells

scientific article published on 01 August 1989

Human clathrin heavy chain (CLTC): partial molecular cloning, expression, and mapping of the gene to human chromosome 17q11-qter

scientific article

Human perlecan immunopurified from different endothelial cell sources has different adhesive properties for vascular cells.

scientific article published on April 1999

Identification of a bimodal regulatory element encompassing a canonical AP-1 binding site in the proximal promoter region of the human decorin gene.

scientific article

Identification of the precursor protein for the heparan sulfate proteoglycan of human colon carcinoma cells and its post-translational modifications

scientific article published on 01 February 1989

Impaired posterior frontal sutural fusion in the biglycan/decorin double deficient mice.

scientific article published on 26 December 2006

In vivo selective and distant killing of cancer cells using adenovirus-mediated decorin gene transfer.

scientific article

Influence of Decorin and Biglycan on Mechanical Properties of Multiple Tendons in Knockout Mice

scientific article published on 01 February 2005

Influence of Decorin and Biglycan on Tensile Viscoelastic Properties in Knockout Mice

Influence of cyclic strain and decorin deficiency on 3D cellularized collagen matrices.

scientific article published on 3 April 2008

Influence of decorin on the mechanical, compositional, and structural properties of the mouse patellar tendon.

scientific article published on March 2012

Inhibition of DNA topoisomerase I activity by heparan sulfate and modulation by basic fibroblast growth factor.

scientific article published in June 1998

Insights into the key roles of proteoglycans in breast cancer biology and translational medicine

scientific article

Instructive roles of extracellular matrix on autophagy.

scientific article published on 26 June 2014

Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A

scientific article published on 8 February 2012

Integrin alpha2beta1 is the required receptor for endorepellin angiostatic activity

scientific article published on 15 November 2007

Intracellularly-retained decorin lacking the C-terminal ear repeat causes ER stress: a cell-based etiological mechanism for congenital stromal corneal dystrophy.

scientific article published on 15 May 2013

Investigating Tendon Fascicle Structure–Function Relationships in a Transgenic-Age Mouse Model Using Multiple Regression Models

scientific article published on 01 July 2004

Isolation and purification of proteoglycans.

scientific article published on January 2002

Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology

scientific article

Large animal model of left ventricular aneurysm

scientific article published on 01 December 1989

Larsen's syndrome with novel congenital anomalies

scientific article published on 01 October 1991

Leukemia treatment in severe combined immunodeficiency mice by antisense oligodeoxynucleotides targeting cooperating oncogenes

scientific article

Ligand-mediated endocytosis and trafficking of the insulin-like growth factor receptor I and insulin receptor modulate receptor function.

scientific article

MITOSTATIN, a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer

scientific article

MURCS association with additional congenital anomalies

scientific article published in January 1986

Mapping of the versican proteoglycan gene (CSPG2) to the long arm of human chromosome 5 (5q12-5q14)

scientific article (publication date: December 1992)

Mast cells produce novel shorter forms of perlecan that contain functional endorepellin: a role in angiogenesis and wound healing.

scientific article published on 12 December 2012

Matrix proteoglycans: from molecular design to cellular function

scientific article

Mechanisms of Progranulin Action and Regulation in Genitourinary Cancers

scientific article

Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin.

scientific article

Methods for Monitoring Matrix-Induced Autophagy

scientific article published on 01 January 2019

Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis

scientific article

Mitostatin Is Down-Regulated in Human Prostate Cancer and Suppresses the Invasive Phenotype of Prostate Cancer Cells ⬇️

scientific article published on May 6, 2011

Model structure of decorin and implications for collagen fibrillogenesis

scientific article

Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan

scientific article

Myristoylation of heparan sulfate proteoglycan and proteins occurs post-translationally in human colon carcinoma cells

scientific article published on 01 October 1990

Neoplastic modulation of extracellular matrix: Stimulation of chondroitin sulfate proteoglycan and hyaluronic acid synthesis in co-cultures of human colon carcinoma and smooth muscle cells

article

Novel interactions of perlecan: unraveling perlecan's role in angiogenesis.

scientific article published on May 2008

Oncogenic activin C interacts with decorin in colorectal cancer in vivo and in vitro

scientific article published on 28 October 2015

Oncosuppressive functions of decorin

scientific article published on 25 February 2015

Osteoblastic cell secretome: a novel role for progranulin during risedronate treatment

scientific article

Overexpression of bamacan/SMC3 causes transformation

scientific article (publication date: 7 July 2000)

Pancreatic injury in rats induced by fatty acid ethyl ester, a nonoxidative metabolite of alcohol

scientific article published on 01 July 1997

Pathophysiological mechanisms of autosomal dominant congenital stromal corneal dystrophy: C-terminal-truncated decorin results in abnormal matrix assembly and altered expression of small leucine-rich proteoglycans

scientific article

Perlecan Proteolysis Induces an α2β1 Integrin- and Src Family Kinase-dependent Anti-apoptotic Pathway in Fibroblasts in the Absence of Focal Adhesion Kinase Activation

scientific article published in Journal of Biological Chemistry

Perlecan heparan sulfate proteoglycan: a novel receptor that mediates a distinct pathway for ligand catabolism

scientific article published on August 2000

Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis.

scientific article

Perlecan: a gem of a proteoglycan

scientific article (publication date: April 1994)

Perlecan: the multidomain heparan sulphate proteoglycan of basement membrane and extracellular matrix

scientific article published in January 1993

Proepithelin Promotes Migration and Invasion of 5637 Bladder Cancer Cells through the Activation of ERK1/2 and the Formation of a Paxillin/FAK/ERK Complex

scientific article published on 01 July 2006

Proepithelin is an autocrine growth factor for bladder cancer

scientific article published on 23 February 2009

Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth.

scientific article published on 29 January 2009

Progranulin/EphA2 axis: A novel oncogenic mechanism in bladder cancer

scientific article published on 14 May 2020

Proteoglycan form and function: A comprehensive nomenclature of proteoglycans

scientific article

Proteoglycan neofunctions: regulation of inflammation and autophagy in cancer biology.

scientific article published on 17 November 2016

Proteoglycan signaling in tumor angiogenesis and endothelial cell autophagy

scientific article published on 09 May 2019

Proteoglycan-driven Autophagy: A Nutrient-independent Mechanism to Control Intracellular Catabolism

scientific article published on 06 July 2020

Proteoglycans and neoplasia

scientific article published on April 1988

Proteoglycans in cancer biology, tumour microenvironment and angiogenesis ⬇️

scientific article published on May 1, 2011

Proteoglycans in health and disease: emerging concepts and future directions ⬇️

scientific article published on October 1, 2010

Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine‐rich proteoglycans ⬇️

scientific article published on August 31, 2010

Proteoglycans regulate autophagy via outside-in signaling: an emerging new concept

scientific article published on 10 October 2015

Proteomic profiling of endorepellin angiostatic activity on human endothelial cells

scientific article published on 12 February 2008

Receptors for and bioresponses to 1,25-dihydroxyvitamin D in a human colon carcinoma cell line (HT-29)

scientific article published on 01 November 1989

Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury ⬇️

scientific article

Reprint of: Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells

scientific article published on 12 April 2014

Retracted: Proline-Rich Tyrosine Kinase 2 (Pyk2) Regulates IGF-I-Induced Cell Motility and Invasion of Urothelial Carcinoma Cells

retracted article

Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity

scientific article published on 29 September 2009

Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis

scientific article

Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21

scientific article

Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation.

scientific article

Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation ⬇️

scientific article published on 09 February 2012

Soluble biglycan as a biomarker of inflammatory renal diseases

scientific article

Sortilin regulates progranulin action in castration-resistant prostate cancer cells

scientific article

Stimulation of protein synthesis in isolated pancreatic acini from chronically ethanol-fed rats is due to alterations in post-transcriptional regulation

scientific article published on 01 October 1993

Strain-rate sensitive mechanical properties of tendon fascicles from mice with genetically engineered alterations in collagen and decorin

scientific article published in April 2004

Structural and functional characterization of the human perlecan gene promoter. Transcriptional activation by transforming growth factor-beta via a nuclear factor 1-binding element

scientific article

Systemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone Metastases

scientific article

Targeted disruption of two small leucine-rich proteoglycans, biglycan and decorin, excerpts divergent effects on enamel and dentin formation

scientific article published on 5 November 2005

Targeting heparanase for cancer therapy at the tumor–matrix interface

scientific article published on 01 June 2012

Targeting perlecan in human keratinocytes reveals novel roles for perlecan in epidermal formation

scientific article

The biology of small leucine-rich proteoglycans in bone pathophysiology

scientific article

The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins

scientific article (publication date: 2 July 1999)

The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases

scientific article

The dermatan sulfate proteoglycan decorin modulates α2β1 integrin and the vimentin intermediate filament system during collagen synthesis

scientific article

The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis

scientific article

The human decorin gene: intron-exon organization, discovery of two alternatively spliced exons in the 5' untranslated region, and mapping of the gene to chromosome 12q23

scientific article

The injury response of aged tendons in the absence of biglycan and decorin.

scientific article published on 21 October 2013

The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-activated protein kinase-dependent activation of paxillin

scientific article

The location-specific role of proteoglycans in the flexor carpi ulnaris tendon

scientific article published on 10 October 2013

The murine biglycan: complete cDNA cloning, genomic organization, promoter function, and expression

scientific article published in November 1995

The proteoglycan perlecan is expressed in the erythroleukemia cell line K562 and is upregulated by sodium butyrate and phorbol ester

scientific article published on April 1995

The role for decorin in delayed-type hypersensitivity

scientific article published on 31 October 2011

The role of decorin in collagen fibrillogenesis and skin homeostasis

scientific article

The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy

scientific article (publication date: 2015)

The role of proteomics in the assessment of premature rupture of fetal membranes.

scientific article

The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling.

scientific article published on 06 February 2014

The systemic delivery of an oncolytic adenovirus expressing decorin inhibits bone metastasis in a mouse model of human prostate cancer.

scientific article

The tendon injury response is influenced by decorin and biglycan

scientific article published on 27 September 2013

The αvβ6 integrin is transferred intercellularly via exosomes

scientific article

Thrombospondins in physiology and disease: new tricks for old dogs

scientific article

Topographical variation in the distributions of versican, aggrecan and perlecan in the foetal human spine reflects their diverse functional roles in spinal development

scientific article published on 11 August 2009

Transcriptional Silencing of Perlecan Gene Expression by Interferon-γ ⬇️

scientific article published on February 20, 1998

Tumor microenvironment: Modulation by decorin and related molecules harboring leucine-rich tandem motifs.

scientific article published on December 2008

Ultrastructural localization of the major proteoglycan and type II procollagen in organelles and extracellular matrix of cultured chondroblasts

scientific article published in January 1986

Urinary proteomic analysis of chronic allograft nephropathy

scientific article

Uterine dysfunction in biglycan and decorin deficient mice leads to dystocia during parturition

scientific article

c-Src, Insulin-Like Growth Factor I Receptor, G-Protein-Coupled Receptor Kinases and Focal Adhesion Kinase are Enriched Into Prostate Cancer Cell Exosomes

scientific article published on 27 May 2016

αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor

scientific article

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