List of works - Onn Min Kon

A UK-based resource to support the monitoring and safe use of anti-TB drugs and second-line treatment of multidrug-resistant TB.

scientific article published on 13 June 2014

A comparison between interferon gamma release assays and the tuberculin skin test in the contact tracing of patients with chronic kidney disease

scientific article published on 14 October 2010

A comparison between two strategies for monitoring hepatic function during antituberculous therapy

scientific article published on 28 December 2011

A mycolic acid-specific CD1-restricted T cell population contributes to acute and memory immune responses in human tuberculosis infection

scientific article

A novel flow cytometric assay of human whole blood neutrophil and monocyte CD11b levels: Upregulation by chemokines is related to receptor expression, comparison with neutrophil shape change, and effects of a chemokine receptor (CXCR2) antagonist

scientific article published on 06 January 2006

A presentation of Poncet's disease identified following immunosuppressive steroid therapy [Correspondence]

scientific article published on 01 May 2012

Airway inflammation and illness severity in response to experimental rhinovirus infection in asthma

scientific article

An experimental model of rhinovirus induced chronic obstructive pulmonary disease exacerbations: a pilot study

scientific article

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis ⬇️

scientific article (publication date: 19 August 2010)

Anticholinergic Bronchodilators

Author's reply to Clifford and colleagues

scientific article published in the British Medical Journal

Authors' response

Breath metabolite response to major upper gastrointestinal surgery

scientific article

Bronchoscopic Techniques for Treating Emphysema

CXC chemokines and antimicrobial peptides in rhinovirus-induced experimental asthma exacerbations.

scientific article

Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium

scientific article

Community-based evaluation of immigrant tuberculosis screening using interferon γ release assays and tuberculin skin testing: observational study and economic analysis

scientific article published on 12 June 2012

Concomitant use of nonnucleoside analogue reverse transcriptase inhibitors and rifampicin in TB/HIV type 1-coinfected patients

scientific article published in July 2008

Cystic lung lesions as an immune reconstitution inflammatory syndrome (IRIS) in HIV-TB co-infection?

scientific article

Cytokine production by bronchoalveolar lavage T lymphocytes in chronic obstructive pulmonary disease

article

Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort.

scientific article published on 15 May 2018

Do we need bacteriological confirmation of cure in uncomplicated tuberculosis?

scientific article published in September 2013

Don’t blame the bones!

scientific article published on 09 October 2010

ESX1-dependent fractalkine mediates chemotaxis and Mycobacterium tuberculosis infection in humans

scientific article

Effect of treatment of latent tuberculosis infection on the T cell response to Mycobacterium tuberculosis antigens

scientific article published on 29 December 2005

Enumeration of functional T-cell subsets by fluorescence-immunospot defines signatures of pathogen burden in tuberculosis

scientific article

Erratum: RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

scientific article published on 9 March 2016

Evaluation of screening methods for identification of patients with chronic rheumatological disease requiring tuberculosis chemoprophylaxis prior to commencement of TNF-α antagonist therapy

scientific article published on 23 August 2013

Exhaled breath acetone for therapeutic monitoring in pneumonia using selected ion flow tube mass spectrometry (SIFT-MS)

scholarly article by Juzheng Huang et al published 2013 in Analytical Methods

Experimental rhinovirus infection as a human model of chronic obstructive pulmonary disease exacerbation

scientific article

Expression of high-affinity IgE receptors (FcϵRI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: Relationship to total serum IgE concentrations

scientific article published on 01 May 1997

Expression of transient receptor potential C6 channels in human lung macrophages.

scientific article published on 20 October 2009

Fluoroquinolones and isoniazid-resistant tuberculosis: implications for the 2018 WHO guidance

scientific article published on 10 October 2019

GeneXpert® MTB/RIF in low prevalence settings: A UK laboratory perspective

article

Granulomatous mediastinal adenopathy: can endoscopic ultrasound-guided fine-needle aspiration differentiate between tuberculosis and sarcoidosis?

scientific article published on 10 August 2011

IFN gamma and CXCR-1 gene polymorphisms in idiopathic bronchiectasis

scientific article

IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo.

scientific article

Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons

scientific article

Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways.

scientific article

International spread of MDR TB from Tugela Ferry, South Africa

scientific article published in November 2011

Letter in response to TB during TNF- inhibitor therapy, despite screening

scientific article published on 29 October 2014

Lymphocyte subsets in experimental rhinovirus infection in chronic obstructive pulmonary disease

scientific article published on 22 September 2013

Multidrug- and extensively drug-resistant tuberculosis: an emerging threat

scientific article published on 01 December 2009

Multidrug-resistant tuberculosis (MDR-TB) treatment in the UK: a study of injectable use and toxicity in practice

scientific article

Mycobacterium vaccae: a study of safety and outcome measures

scientific article published on 01 March 1998

Nasal Lipopolysaccharide Challenge and Cytokine Measurement Reflects Innate Mucosal Immune Responsiveness

scientific article published on 14 September 2015

Neutrophil adhesion molecules in experimental rhinovirus infection in COPD.

scientific article published on 08 July 2013

New Drugs for the Treatment of Allergy and Asthma

Optimized dialysis and protease inhibition of sputum dithiothreitol supernatants

scientific article published on 25 October 2007

Outgrowth of the bacterial airway microbiome after rhinovirus exacerbation of chronic obstructive pulmonary disease.

scientific article

Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD.

scientific article

PD-1 Expression and Cytokine Secretion Profiles of Mycobacterium tuberculosis-Specific CD4+ T-Cell Subsets; Potential Correlates of Containment in HIV-TB Co-Infection

scientific article published on 12 January 2016

Paradoxical reactions in non-HIV tuberculosis presenting as endobronchial obstruction

article

Parasitic infections of the lung: a guide for the respiratory physician.

scientific article published on 29 September 2010

Patterns of systemic and local inflammation in patients with asthma hospitalised with influenza

scientific article published on 24 October 2019

Performance of Xpert MTB/RIF in the diagnosis of tuberculous mediastinal lymphadenopathy by endobronchial ultrasound

scientific article

Post-bronchoscopy sputum: improving the diagnostic yield in smear negative pulmonary TB.

scientific article published on 15 August 2011

Primary nodal anthracosis identified by EBUS-TBNA as a cause of FDG PET/CT positive mediastinal lymphadenopathy

scientific article published on 27 September 2013

Prognostic value of interferon-γ release assays and tuberculin skin test in predicting the development of active tuberculosis (UK PREDICT TB): a prospective cohort study

scholarly article by Ibrahim Abubakar et al published October 2018 in Lancet Infectious Diseases

Programmed death ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosis

scientific article

Protocol for a human in vivo model of acute cigarette smoke inhalation challenge in smokers with COPD: monitoring the nasal and systemic immune response using a network biology approach

scientific article

Pulmonary infection with Cryptococcus neoformans in the face of underlying sarcoidosis

scientific article

Pulmonary venous stenosis after treatment for atrial fibrillation.

scientific article published on April 2008

RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

scientific article

Randomised, dose-ranging, placebo-controlled study of chimeric antibody to CD4 (keliximab) in chronic severe asthma

scientific article

Rapid effect of inhaled ciclesonide in asthma: a randomized, placebo-controlled study

scientific article published on 10 April 2008

Reduction of persistent air leak with endoscopic valve implants

scientific article

Rhinovirus 16-induced IFN-α and IFN-β are deficient in bronchoalveolar lavage cells in asthmatic patients.

scientific article

Rhinovirus induces MUC5AC in a human infection model and in vitro via NF-κB and EGFR pathways.

scientific article

Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary disease

scientific article

Rhinovirus-induced interferon production is not deficient in well controlled asthma

scientific article published on 14 October 2013

Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production

scholarly article

Risk factors for the misdiagnosis of tuberculosis in the UK, 2001–2011: TABLE 1

scholarly article by Debora Pedrazzoli et al published 16 April 2015 in European Respiratory Journal

Role of deficient type III interferon-λ production in asthma exacerbations

article

Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection.

scientific article

Sarcoidosis and tuberculosis cytokine profiles: indistinguishable in bronchoalveolar lavage but different in blood.

scientific article

Screening for latent tuberculosis before tumour necrosis factor antagonist therapy.

scientific article

Screening of immigrants in the UK for imported latent tuberculosis: a multicentre cohort study and cost-effectiveness analysis

scientific article published on 20 April 2011

Screening tests for tuberculosis before starting biological therapy

scientific article

Smoking cessation in COPD causes a transient improvement in spirometry and decreases micronodules on high-resolution CT imaging.

scientific article

Soluble major histocompatibility complex class I-related chain B molecules are increased and correlate with clinical outcomes during rhinovirus infection in healthy subjects

scientific article

Subretinal Pseudomonas abscess in a patient with bronchiectasis

scientific article published in February 2004

T-cell immunophenotyping distinguishes active from latent tuberculosis

scientific article published on September 2013

TLR3, TLR4 and TLRs7-9 Induced Interferons Are Not Impaired in Airway and Blood Cells in Well Controlled Asthma

scientific article

The cardiopulmonary effects of physical restraint in subjects with chronic obstructive pulmonary disease

scientific article published on 23 December 2004

The effects of a monoclonal antibody directed against tumor necrosis factor-alpha in asthma

scientific article published on 13 July 2006

The effects of an anti-CD4 monoclonal antibody, keliximab, on peripheral blood CD4+ T-cells in asthma

scientific article published on 01 July 2001

The effects of an anti-IL-13 mAb on cytokine levels and nasal symptoms following nasal allergen challenge

scientific article published on 29 June 2011

The national TB strategy: jointly taking responsibility for TB control?

scientific article published on 3 February 2015

The pulmonary physician in critical care * Illustrative case 5: HIV associated pneumonia.

scientific article

The role of IL-15 deficiency in the pathogenesis of virus-induced asthma exacerbations

scientific article

The use of thoracic computed tomography scanning and EBUS-TBNA to diagnose tuberculosis of the central nervous system: two case reports.

scientific article published in December 2010

Time for a preventative strategy for TB in the UK: further evidence for new entrant screening in primary care

scientific article published on 2 January 2014

Time to diagnosis of tuberculosis is greater in older patients: a retrospective cohort review

scientific article published on 01 October 2019

Toll-like receptor 2, 3, and 4 expression and function in human airway smooth muscle

scientific article published on 03 July 2006

Two cases of culture proven Mycobacterium tuberculosis presenting with a broad-complex tachycardia and non-caseating granulomas

scientific article published on 16 April 2014

Two interferon gamma release assays for predicting active tuberculosis: the UK PREDICT TB prognostic test study

article by Ibrahim Abubakar et al published October 2018 in Health Technology Assessment

Update on tuberculosis: TB in the early 21st century

scientific article published on June 2011

Utility of endobronchial ultrasound-guided transbronchial needle aspiration in patients with tuberculous intrathoracic lymphadenopathy: a multicentre study

scientific article

Viral hepatitis prevalence in patients with active and latent tuberculosis

scientific article published in August 2015

Vitamin D deficiency and TB disease phenotype

scientific article

γδT cells suppress inflammation and disease during rhinovirus-induced asthma exacerbations.

scientific article published on 06 February 2013

List of works by Onn Min Kon

A UK-based resource to support the monitoring and safe use of anti-TB drugs and second-line treatment of multidrug-resistant TB.

A comparison between interferon gamma release assays and the tuberculin skin test in the contact tracing of patients with chronic kidney disease

A comparison between two strategies for monitoring hepatic function during antituberculous therapy

A mycolic acid-specific CD1-restricted T cell population contributes to acute and memory immune responses in human tuberculosis infection

A novel flow cytometric assay of human whole blood neutrophil and monocyte CD11b levels: Upregulation by chemokines is related to receptor expression, comparison with neutrophil shape change, and effects of a chemokine receptor (CXCR2) antagonist

A presentation of Poncet's disease identified following immunosuppressive steroid therapy [Correspondence]

Airway inflammation and illness severity in response to experimental rhinovirus infection in asthma

An experimental model of rhinovirus induced chronic obstructive pulmonary disease exacerbations: a pilot study

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis ⬇️

Anticholinergic Bronchodilators

Author's reply to Clifford and colleagues

Authors' response

Breath metabolite response to major upper gastrointestinal surgery

Bronchoscopic Techniques for Treating Emphysema

CXC chemokines and antimicrobial peptides in rhinovirus-induced experimental asthma exacerbations.

Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium

Community-based evaluation of immigrant tuberculosis screening using interferon γ release assays and tuberculin skin testing: observational study and economic analysis

Concomitant use of nonnucleoside analogue reverse transcriptase inhibitors and rifampicin in TB/HIV type 1-coinfected patients

Cystic lung lesions as an immune reconstitution inflammatory syndrome (IRIS) in HIV-TB co-infection?

Cytokine production by bronchoalveolar lavage T lymphocytes in chronic obstructive pulmonary disease

Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort.

Do we need bacteriological confirmation of cure in uncomplicated tuberculosis?

Don’t blame the bones!

ESX1-dependent fractalkine mediates chemotaxis and Mycobacterium tuberculosis infection in humans

Effect of treatment of latent tuberculosis infection on the T cell response to Mycobacterium tuberculosis antigens

Enumeration of functional T-cell subsets by fluorescence-immunospot defines signatures of pathogen burden in tuberculosis

Erratum: RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

Evaluation of screening methods for identification of patients with chronic rheumatological disease requiring tuberculosis chemoprophylaxis prior to commencement of TNF-α antagonist therapy

Exhaled breath acetone for therapeutic monitoring in pneumonia using selected ion flow tube mass spectrometry (SIFT-MS)

Experimental rhinovirus infection as a human model of chronic obstructive pulmonary disease exacerbation

Expression of high-affinity IgE receptors (FcϵRI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: Relationship to total serum IgE concentrations

Expression of transient receptor potential C6 channels in human lung macrophages.

Fluoroquinolones and isoniazid-resistant tuberculosis: implications for the 2018 WHO guidance

GeneXpert® MTB/RIF in low prevalence settings: A UK laboratory perspective

Granulomatous mediastinal adenopathy: can endoscopic ultrasound-guided fine-needle aspiration differentiate between tuberculosis and sarcoidosis?

IFN gamma and CXCR-1 gene polymorphisms in idiopathic bronchiectasis

IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo.

Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons

Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways.

International spread of MDR TB from Tugela Ferry, South Africa

Letter in response to TB during TNF- inhibitor therapy, despite screening

Lymphocyte subsets in experimental rhinovirus infection in chronic obstructive pulmonary disease

Multidrug- and extensively drug-resistant tuberculosis: an emerging threat

Multidrug-resistant tuberculosis (MDR-TB) treatment in the UK: a study of injectable use and toxicity in practice

Mycobacterium vaccae: a study of safety and outcome measures

Nasal Lipopolysaccharide Challenge and Cytokine Measurement Reflects Innate Mucosal Immune Responsiveness

Neutrophil adhesion molecules in experimental rhinovirus infection in COPD.

New Drugs for the Treatment of Allergy and Asthma

Optimized dialysis and protease inhibition of sputum dithiothreitol supernatants

Outgrowth of the bacterial airway microbiome after rhinovirus exacerbation of chronic obstructive pulmonary disease.

Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD.

PD-1 Expression and Cytokine Secretion Profiles of Mycobacterium tuberculosis-Specific CD4+ T-Cell Subsets; Potential Correlates of Containment in HIV-TB Co-Infection

Paradoxical reactions in non-HIV tuberculosis presenting as endobronchial obstruction

Parasitic infections of the lung: a guide for the respiratory physician.

Patterns of systemic and local inflammation in patients with asthma hospitalised with influenza

Performance of Xpert MTB/RIF in the diagnosis of tuberculous mediastinal lymphadenopathy by endobronchial ultrasound

Post-bronchoscopy sputum: improving the diagnostic yield in smear negative pulmonary TB.

Primary nodal anthracosis identified by EBUS-TBNA as a cause of FDG PET/CT positive mediastinal lymphadenopathy

Prognostic value of interferon-γ release assays and tuberculin skin test in predicting the development of active tuberculosis (UK PREDICT TB): a prospective cohort study

Programmed death ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosis

Protocol for a human in vivo model of acute cigarette smoke inhalation challenge in smokers with COPD: monitoring the nasal and systemic immune response using a network biology approach

Pulmonary infection with Cryptococcus neoformans in the face of underlying sarcoidosis

Pulmonary venous stenosis after treatment for atrial fibrillation.

RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

Randomised, dose-ranging, placebo-controlled study of chimeric antibody to CD4 (keliximab) in chronic severe asthma

Rapid effect of inhaled ciclesonide in asthma: a randomized, placebo-controlled study

Reduction of persistent air leak with endoscopic valve implants

Rhinovirus 16-induced IFN-α and IFN-β are deficient in bronchoalveolar lavage cells in asthmatic patients.

Rhinovirus induces MUC5AC in a human infection model and in vitro via NF-κB and EGFR pathways.

Rhinovirus infection induces degradation of antimicrobial peptides and secondary bacterial infection in chronic obstructive pulmonary disease

Rhinovirus-induced interferon production is not deficient in well controlled asthma

Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production

Risk factors for the misdiagnosis of tuberculosis in the UK, 2001–2011: TABLE 1

Role of deficient type III interferon-λ production in asthma exacerbations

Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection.

Sarcoidosis and tuberculosis cytokine profiles: indistinguishable in bronchoalveolar lavage but different in blood.

Screening for latent tuberculosis before tumour necrosis factor antagonist therapy.

Screening of immigrants in the UK for imported latent tuberculosis: a multicentre cohort study and cost-effectiveness analysis

Screening tests for tuberculosis before starting biological therapy