List of works - Ghader Bashiri

A NADH-accepting imine reductase variant: Immobilization and cofactor regeneration by oxidative deamination

scientific article published on 6 May 2016

A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography

scientific article

A new Gateway vector and expression protocol for fast and efficient recombinant protein expression in Mycobacterium smegmatis

scientific article published on 14 September 2007

A revised biosynthetic pathway for the cofactor F in prokaryotes

scientific article published on 05 April 2019

Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2

scientific article published on 11 October 2019

Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogen Mycobacterium tuberculosis

scientific article published on 06 February 2020

Biosynthesis of the Thiopeptins and Identification of an F420H2-Dependent Dehydropiperidine Reductase

scientific article published on 17 August 2018

Characterization of the proline-utilization pathway in Mycobacterium tuberculosis through structural and functional studies

scientific article

Cloning, expression, purification, crystallization and preliminary X-ray studies of the C-terminal domain of Rv3262 (FbiB) from Mycobacterium tuberculosis ⬇️

scientific article published on September 30, 2011

Comparative bioactivation of the novel anti-tuberculosis agent PA-824 in Mycobacteria and a subcellular fraction of human liver

scientific article

Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein

scientific article

Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding

scientific article

Development of NMR and thermal shift assays for the evaluation of isocitrate lyase inhibitors

scientific article published in November 2017

Different Reaction Specificities of F420H2-Dependent Reductases Facilitate Pyrrolobenzodiazepines and Lincomycin To Fit Their Biological Targets

scientific article published on 28 January 2020

Elongation of the Poly-γ-glutamate Tail of F420 Requires Both Domains of the F420:γ-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis

scientific article

Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system

scientific article

Mass spectral determination of phosphopantetheinylation specificity for carrier proteins in Mycobacterium tuberculosis

scientific article published on 24 October 2016

Metabolic engineering of cofactor F420 production in Mycobacterium smegmatis

scientific article

PdxH proteins of mycobacteria are typical members of the classical pyridoxine/pyridoxamine 5'-phosphate oxidase family

scientific article published on 29 January 2016

Production of recombinant proteins in Mycobacterium smegmatis for structural and functional studies

scientific article

Regulation and Quality Control of Adiponectin Assembly by Endoplasmic Reticulum Chaperone ERp44.

scientific article published on 9 June 2015

Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms

scientific article

Structural biology of enzymes involved in the activation of the anti-TB prodrug PA-824

2009 doctoral thesis by Ghader Bashiri at University of Auckland

Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex

scientific article

Tat-dependent translocation of an F420-binding protein of Mycobacterium tuberculosis

scientific article

The active site of the Mycobacterium tuberculosis branched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster

scientific article published on 16 July 2019

Uncovering the enzymes that catalyze the final steps in oxytetracycline biosynthesis

scientific article

Use of a "silver bullet" to resolve crystal lattice dislocation disorder: a cobalamin complex of Δ1-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis

scientific article

List of works by Ghader Bashiri

A NADH-accepting imine reductase variant: Immobilization and cofactor regeneration by oxidative deamination

A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography

A new Gateway vector and expression protocol for fast and efficient recombinant protein expression in Mycobacterium smegmatis

A revised biosynthetic pathway for the cofactor F in prokaryotes

Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2

Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogen Mycobacterium tuberculosis

Biosynthesis of the Thiopeptins and Identification of an F420H2-Dependent Dehydropiperidine Reductase

Characterization of the proline-utilization pathway in Mycobacterium tuberculosis through structural and functional studies

Cloning, expression, purification, crystallization and preliminary X-ray studies of the C-terminal domain of Rv3262 (FbiB) from Mycobacterium tuberculosis ⬇️

Comparative bioactivation of the novel anti-tuberculosis agent PA-824 in Mycobacteria and a subcellular fraction of human liver

Crystal structure of the essential Mycobacterium tuberculosis phosphopantetheinyl transferase PptT, solved as a fusion protein with maltose binding protein

Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding

Development of NMR and thermal shift assays for the evaluation of isocitrate lyase inhibitors

Different Reaction Specificities of F420H2-Dependent Reductases Facilitate Pyrrolobenzodiazepines and Lincomycin To Fit Their Biological Targets

Elongation of the Poly-γ-glutamate Tail of F420 Requires Both Domains of the F420:γ-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis

Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system

Mass spectral determination of phosphopantetheinylation specificity for carrier proteins in Mycobacterium tuberculosis

Metabolic engineering of cofactor F420 production in Mycobacterium smegmatis

PdxH proteins of mycobacteria are typical members of the classical pyridoxine/pyridoxamine 5'-phosphate oxidase family

Production of recombinant proteins in Mycobacterium smegmatis for structural and functional studies

Regulation and Quality Control of Adiponectin Assembly by Endoplasmic Reticulum Chaperone ERp44.

Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms

Structural biology of enzymes involved in the activation of the anti-TB prodrug PA-824

Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex

Tat-dependent translocation of an F420-binding protein of Mycobacterium tuberculosis

The active site of the Mycobacterium tuberculosis branched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster

Uncovering the enzymes that catalyze the final steps in oxytetracycline biosynthesis

Use of a "silver bullet" to resolve crystal lattice dislocation disorder: a cobalamin complex of Δ1-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis