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List of works by Jeffrey R. Deschamps

(1R)-2-[(3R,4S)-3-Methyl-4-(N-phenyl-N-propionylamino)piperidin-1-yl]-1-phenylethyl p-bromobenzoate and N-[(3R,4S)-1-[(2S)-2-(4-bromophenyl)-2-hydroxyethyl]-3-methyl-piperidin-4-yl]-N-phenylacrylamide

scientific article published on 31 May 2002

1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors

scientific article

A concise method for the preparation of deuterium-labeled cortisone: synthesis of [6,7-2H]cortisone

scientific article published on October 2005

A fluorescence resonance energy transfer-derived structure of a quantum dot-protein bioconjugate nanoassembly

scholarly article

A hybrid quantum dot-antibody fragment fluorescence resonance energy transfer-based TNT sensor

scientific article published in May 2005

A new synthesis of the ORL-1 antagonist 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay

scientific article

A novel series of piperidin-4-yl-1,3-dihydroindol-2-ones as agonist and antagonist ligands at the nociceptin receptor

scientific article published on June 2004

A partial primary structure of squid hepatopancreas organophosphorus acid anhydrolase

scientific article published on 01 June 1993

A study of the structure-activity relationship of GABA(A)-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis

scientific article published on 02 September 2008

A topographically and conformationally constrained, spin-labeled, alpha-amino acid: crystallographic characterization in peptides*

scientific article published on 01 June 2005

Adamantyl cannabinoids: a novel class of cannabinergic ligands

scientific article

Analyzing Nanomaterial Bioconjugates: A Review of Current and Emerging Purification and Characterization Techniques ⬇️

scientific article published on 05 May 2011

Application of silver N-heterocyclic carbene complexes in O-glycosidation reactions

scientific article published on 2 August 2011

Boc-protected 1-(3-oxocycloalkyl)ureas via a one-step Curtius rearrangement: mechanism and scope

scientific article published on January 2014

Brønsted acid mediated cyclization of enaminones. Rapid and efficient access to the tetracyclic framework of the Strychnos alkaloids

scientific article published on 18 January 2012

C4-alkylthiols with activity against Moraxella catarrhalis and Mycobacterium tuberculosis

scientific article published on October 2011

CJ-1639: A Potent and Highly Selective Dopamine D3 Receptor Full Agonist

scientific article

Characterization and performance evaluation of in vivo and in vitro produced monoclonal anti-TNT antibodies for the detection of TNT.

scientific article

Chemistry of the diazeniumdiolates. O- versus N-alkylation of the RNH[N(O)NO](-) ion.

scientific article published in October 2004

Chiral Resolution and Serendipitous Fluorination Reaction for the Selective Dopamine D3 Receptor Antagonist BAK2-66

scientific article

Chiral resolution and absolute configuration of the enantiomers of the psychoactive "designer drug" 3,4-methylenedioxypyrovalerone.

scientific article

Comparison of organophosphorous acid anhydrolases from different species using monoclonal antibodies

scientific article published on 01 November 1993

Competition between Förster resonance energy transfer and electron transfer in stoichiometrically assembled semiconductor quantum dot-fullerene conjugates

scientific article

Concise Total Synthesis of (-)-Affinisine Oxindole, (+)-Isoalstonisine, (+)-Alstofoline, (-)-Macrogentine, (+)-Na -Demethylalstonisine, (-)-Alstonoxine A, and (+)-Alstonisine

scientific article

Configurational reassignment and improved preparation of the competitive IL-6 receptor antagonist 20R,21R-epoxyresibufogenin-3-formate

scientific article

Conformational Details of Quantum Dot-DNA Resolved by Förster Resonance Energy Transfer Lifetime Nanoruler

scientific article published on 06 December 2018

Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities

scientific article

Crystal structure of biphalin sulfate: a multireceptor opioid peptide.

scientific article

Crystal structures of dipeptides containing the Dmt-Tic pharmacophore

scientific article published in December 2002

Crystal structures of the three closely related compounds: bis-[(1H-tetra-zol-5-yl)meth-yl]nitramide, tri-amino-guanidinium 5-({[(1H-tetra-zol-5-yl)meth-yl](nitro)-amino}-meth-yl)tetra-zol-1-ide, and di-ammonium bis-[(tetra-zol-1-id-5-yl)meth-yl]nit

scientific article published on 20 June 2017

Delivery and tracking of quantum dot peptide bioconjugates in an intact developing avian brain

scientific article (publication date: 18 March 2015)

Design and synthesis of novel antimicrobials with activity against Gram-positive bacteria and mycobacterial species, including M. tuberculosis

scientific article published on 21 October 2013

Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro-mannich ring-opening-cyclization reaction mechanism in spiro-oxindoles.

scientific article published on 12 December 2014

Design, Synthesis, and Biological Evaluation of Structurally Rigid Analogues of 4-(3-Hydroxyphenyl)piperidine Opioid Receptor Antagonists.

scientific article published on 27 July 2016

Detection of explosives in a dynamic marine environment using a moored TNT immunosensor.

scientific article published on 27 February 2014

Diastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors

scientific article published on 03 May 2013

Diastereoselective one-pot synthesis of 7- and 8-substituted 5-phenylmorphans

scientific article

Direct reaction of amides with nitric oxide to form diazeniumdiolates.

scientific article

Discovery of a novel small molecule agonist scaffold for the APJ receptor.

scientific article published on 11 June 2016

Efficacy, but not antibody titer or affinity, of a heroin hapten conjugate vaccine correlates with increasing hapten densities on tetanus toxoid, but not on CRM197 carriers

scientific article published on 5 June 2015

Elucidating Surface Ligand-Dependent Kinetic Enhancement of Proteolytic Activity at Surface-Modified Quantum Dots.

scientific article published on 12 June 2017

Enantiomerically pure hexahydropyrazinoquinolines as potent and selective dopamine 3 subtype receptor ligands

scientific article published in May 2005

Enantioselective synthesis of (2R,3R)- and (2S,3S)-2- [(3-chlorophenyl)-(2-methoxyphenoxy)methyl]morpholine

scientific article

Enantiospecific Allosteric Modulation of Cannabinoid 1 Receptor.

scientific article

Enantiospecific synthesis of (+)-alstonisine via a stereospecific osmylation process

scientific article published on 9 July 2008

Engineering Immunological Tolerance Using Quantum Dots to Tune the Density of Self-Antigen Display

scientific article published on 3 April 2017

Expeditious synthesis, enantiomeric resolution, and enantiomer functional characterization of (4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP-TQS): an allosteric agonist-positive allosteric modulator of α7 nicoti

scientific article published on 25 October 2013

Extraction of Perchlorate Using Porous Organosilicate Materials.

scientific article published on 02 April 2013

Facile Synthesis of Spirocyclic Lactams from β-Keto Carboxylic Acids.

scientific article published on 4 June 2015

Fluorescent silicate materials for the detection of paraoxon.

scientific article published on 19 March 2010

Functionalization of the 6,14-bridge of the orvinols. Part 3: preparation and pharmacological evaluation of 18- and 19-hydroxyl substituted orvinols

scientific article

General Approach for the Synthesis of Sarpagine Indole Alkaloids. Enantiospecific Total Synthesis of (+)-Vellosimine, (+)-Normacusine B, (−)-Alkaloid Q3, (−)-Panarine, (+)-Na-Methylvellosimine, and (+)-Na-Methyl-16-epipericyclivine ⬇️

scientific article published on October 3, 2003

General strategy for synthesis of C-19 methyl-substituted sarpagine/macroline/ajmaline indole alkaloids including total synthesis of 19(S),20(R)-dihydroperaksine, 19(S),20(R)-dihydroperaksine-17-al, and peraksine

scientific article published on 15 October 2014

Growth and development of the barnacle Amphibalanus amphitrite: time and spatially resolved structure and chemistry of the base plate.

scientific article

Hydrolytic reactivity trends among potential prodrugs of the O2-glycosylated diazeniumdiolate family. Targeting nitric oxide to macrophages for antileishmanial activity

scientific article published on 06 June 2008

Identification of neuropeptide S antagonists: structure-activity relationship studies, X-ray crystallography, and in vivo evaluation

scientific article

Integrated metagenomic and metaproteomic analyses of marine biofilm communities.

scientific article published on January 2014

Investigation of Zr(IV) and 89Zr(IV) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging.

scientific article published on 19 December 2012

Iodobenzene-Catalyzed Synthesis of Phenanthridinones via Oxidative C-H Amidation

scientific article published on 28 February 2017

Maltose-binding protein: a versatile platform for prototyping biosensing

scientific article

Method development for metaproteomic analyses of marine biofilms.

scientific article published on 11 April 2012

Modulation of opioid receptor affinity and efficacy via N-substitution of 9β-hydroxy-5-(3-hydroxyphenyl)morphan: Synthesis and computer simulation study

scientific article

Monitoring botulinum neurotoxin a activity with peptide-functionalized quantum dot resonance energy transfer sensors

scientific article published on 28 February 2011

Multi-channeled single chain variable fragment (scFv) based microfluidic device for explosives detection

scientific article published on 20 June 2015

Multiplex charge-transfer interactions between quantum dots and peptide-bridged ruthenium complexes.

scientific article published in June 2009

N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists

scientific article

N-substituted cis-4a-(3-hydroxyphenyl)-8a-methyloctahydroisoquinolines are opioid receptor pure antagonists

scientific article

Nanoparticle cellular uptake by dendritic wedge peptides: achieving single peptide facilitated delivery.

scientific article published on 13 July 2017

Nature-inspired stereospecific total synthesis of P-(+)-dispegatrine and four other monomeric sarpagine indole alkaloids

scientific article published on 16 October 2012

Nitrogen-bound diazeniumdiolated amidines.

scientific article published on 30 June 2010

Non-transpeptidase binding arylthioether β-lactams active against Mycobacterium tuberculosis and Moraxella catarrhalis

scientific article published on 12 December 2014

Nonpeptidic and potent small-molecule inhibitors of cIAP-1/2 and XIAP proteins

scientific article

North- and south-bicyclo[3.1.0]hexene nucleosides: the effect of ring planarity on anti-HIV activity.

scientific article

Novel adamantyl cannabinoids as CB1 receptor probes

scientific article published on 14 May 2013

Novel anticholinesterases based on the molecular skeletons of furobenzofuran and methanobenzodioxepine.

scientific article published on February 2005

O2-Functionalized Methylamine Diazeniumdiolates: Evidence for E ⇄ Z Equilibration in an Acyclic System

article

One-pot sequential reaction to 2-substituted-phenanthridinones from N-methoxybenzamides

scientific article published on 01 May 2017

Optimizing protein coordination to quantum dots with designer peptidyl linkers

scientific article

PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.

scientific article published on February 2006

PABA/NO lead optimization: Improved targeting of cytotoxicity to glutathione S-transferase P1-overexpressing cancer cells.

scientific article published on 19 May 2015

PROBES FOR NARCOTIC RECEPTOR MEDIATED PHENOMENA. 38. AN EXPEDITIOUS SYNTHESIS OF RAC-CIS-4a-ETHYL-2-METHYL-1,2,3,4,4a,9a-HEXAHYDROBENZOFURO[2,3-c]PYRIDIN-6-OL AND RAC-CIS-2-METHYL-4a-PHENETHYL-1,2,3,4,4a,9a-HEXAHYDROBENZOFURO[2,3-c]PYRIDIN-6-OL

scientific article published on January 2009

Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance

scientific article

Polyvalent display and packing of peptides and proteins on semiconductor quantum dots: predicted versus experimental results

scientific article published in February 2010

Porphyrin-embedded silicate materials for detection of hydrocarbon solvents

scientific article

Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor

scientific article

Preparation and initial characterization of crystals of the photoprotein aequorin from Aequorea victoria

scientific article published on 01 January 1993

Probes for narcotic receptor mediated phenomena. 37. Synthesis and opioid binding affinity of the final pair of oxide-bridged phenylmorphans, the ortho- and para-b-isomers and their N-phenethyl analogues, and the synthesis of the N-phenethyl analogu

scientific article published on December 2008

Probes for narcotic receptor mediated phenomena. 40. N-substituted cis-4a-ethyl-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-8-ols

scientific article

Probes for narcotic receptor mediated phenomena. 43. Synthesis of the ortho-a and para-a, and improved synthesis and optical resolution of the ortho-b and para-b oxide-bridged phenylmorphans: compounds with moderate to low opioid-receptor affinity

scientific article

Probes for narcotic receptor mediated phenomena. 44. Synthesis of an N-substituted 4-hydroxy-5-(3-hydroxyphenyl)morphan with high affinity and selective μ-antagonist activity

scientific article published on 20 January 2012

Probes for narcotic receptor mediated phenomena. 46. N-substituted-2,3,4,9,10,10a-hexahydro-1H-1,4a-(epiminoethano)phenanthren-6- and 8-ols - carbocyclic relatives of f-oxide-bridged phenylmorphans

scientific article published on 30 October 2012

Probes for narcotic receptor mediated phenomena. 48. C7- and C8-substituted 5-phenylmorphan opioids from diastereoselective alkylation

scientific article published on 25 June 2013

Probes for narcotic receptor mediated phenomena. Part 42: synthesis and in vitro pharmacological characterization of the N-methyl and N-phenethyl analogues of the racemic ortho-c and para-c oxide-bridged phenylmorphans

scientific article

Probing the Quenching of Quantum Dot Photoluminescence by Peptide-Labeled Ruthenium(II) Complexes

scientific article

Proteolytic Activity at Quantum Dot-Conjugates: Kinetic Analysis Reveals Enhanced Enzyme Activity and Localized Interfacial “Hopping”

scientific article published on 25 June 2012

Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates

scientific article published on 25 June 2006

Quantum Dot-Peptide-Fullerene Bioconjugates for Visualization of in Vitro and in Vivo Cellular Membrane Potential.

scientific article published on 17 May 2017

Quantum dot DNA bioconjugates: attachment chemistry strongly influences the resulting composite architecture

scientific article published on 17 November 2010

Quantum dot display enhances activity of a phosphotriesterase trimer

scientific article published in April 2015

REMUS100 AUV with an integrated microfluidic system for explosives detection

scientific article published on 29 March 2013

Regiospecific, Enantiospecific Total Synthesis of C-19 Methyl Substituted Sarpagine Alkaloids Dihydroperaksine-17-al and Dihydroperaksine ⬇️

scientific article published on August 30, 2011

Regiospecific, Enantiospecific Total Synthesis of the Alkoxy-Substituted Indole Bases, 16-epi-Na-Methylgardneral, 11-Methoxyaffinisine, and 11-Methoxymacroline as Well as the Indole Alkaloids Alstophylline and Macralstonine

scientific article published on 01 October 2002

Reprint of "Which metaproteome? The impact of protein extraction bias on metaproteomic analyses".

scientific article

Resonance Energy Transfer Between Luminescent Quantum Dots and Diverse Fluorescent Protein Acceptors

scientific article

Resonance Energy Transfer in DNA Duplexes Labeled with Localized Dyes

scientific article published on 05 December 2014

Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonist

scientific article published on 4 July 2010

Salvinicins A and B, new neoclerodane diterpenes from Salvia divinorum ⬇️

scientific article published on July 2005

Selecting improved peptidyl motifs for cytosolic delivery of disparate protein and nanoparticle materials

scientific article published on May 2013

Sensing caspase 3 activity with quantum dot-fluorescent protein assemblies

scientific article published in March 2009

Slow-onset, long-duration, alkyl analogues of methylphenidate with enhanced selectivity for the dopamine transporter

scientific article

Solution- and Solid-State Conformations of C(α)-Alkyl Analogues of Methylphenidate (Ritalin) Salts: Avoidance of gauche+gauche– Interactions ⬇️

scientific article published on October 14, 2011

Stereospecific total synthesis of the indole alkaloid ervincidine. Establishment of the C-6 hydroxyl stereochemistry

scientific article published on 18 April 2014

Strain analysis of a chiral smectic-A elastomer

scientific article published on 21 September 2010

Structural Basis of Species-Dependent Differential Affinity of 6-Alkoxy-5-Aryl-3-Pyridinecarboxamide Cannabinoid-1 Receptor Antagonists

scientific article published on 26 May 2015

Structure-activity relationships comparing N-(6-methylpyridin-yl)-substituted aryl amides to 2-methyl-6-(substituted-arylethynyl)pyridines or 2-methyl-4-(substituted-arylethynyl)thiazoles as novel metabotropic glutamate receptor subtype 5 antagonist

scientific article

Structure-activity relationships for a novel series of dopamine D2-like receptor ligands based on N-substituted 3-aryl-8-azabicyclo[3.2.1]octan-3-ol

scientific article

Structure-based design of potent non-peptide MDM2 inhibitors

scientific article published in July 2005

Study of the cis to trans isomerization of 1-phenyl-2,3-disubstituted tetrahydro-beta-carbolines at C(1). Evidence for the carbocation-mediated mechanism

scientific article published on April 2009

Synthesis and immunological effects of heroin vaccines

scientific article published in October 2014

Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans.

scientific article published on 13 June 2008

Synthesis of 1,2-dihydro-2-oxo-4-quinolinyl phosphates from 2-acyl-benzoic acids.

scientific article

Synthesis of 8-thiabicyclo[3.2.1]octanes and their binding affinity for the dopamine and serotonin transporters

scientific article

Synthesis of a 2,2'-bipyridyl functionalized oligovinylene-phenylene using Heck and Horner-Wadsworth-Emmons reactions and X-ray crystal structure of E-(4-(4-bromostyryl)phenyl)(methyl)sulfane

scientific article published on 14 May 2012

Synthesis of aza and carbocyclic β-carbolines for the treatment of alcohol abuse. Regiospecific solution to the problem of 3,6-disubstituted β- and aza-β-carboline specificity

scientific article published on 9 September 2015

Synthesis of bicyclo[3.1.0]hexanes functionalized at the tip of the cyclopropane ring. Application to the synthesis of carbocyclic nucleosides

scientific article published in February 2006

Synthesis of conformationally locked L-deoxythreosyl phosphonate nucleosides built on a bicyclo[3.1.0]hexane template

scientific article

Synthesis of enantiopure 10-nornaltrexones in the search for Toll-like receptor 4 antagonists and opioid ligands

scientific article

Synthesis of salvinorin A analogues as opioid receptor probes

scientific article

Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product

scientific article

Synthetic studies of neoclerodane diterpenes from Salvia divinorum: preparation and opioid receptor activity of salvinicin analogues

scientific article

The role of crystallography in drug design

scientific article published on 07 December 2005

Total Synthesis of Macrocarpines D and E via an Enolate-Driven Copper-Mediated Cross-Coupling Process: Replacement of Catalytic Palladium with Copper Iodide

scientific article published on 16 August 2016

Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D3 Receptor

scientific article

Tyrosinium-D-tetrahydroisoquinoline-3-carboxylate 1.5-Hydrate and Tyrosyl-D-tetrahydroisoquinoline-3-carboxamide Hydrate

scientific article published on 01 October 1997

Understanding How Nanoparticle Attachment Enhances Phosphotriesterase Kinetic Efficiency.

scientific article published on 31 July 2015

Using click chemistry toward novel 1,2,3-triazole-linked dopamine D3 receptor ligands

scientific article published on 17 January 2015

Using conformationally locked nucleosides to calibrate the anomeric effect: Implications for glycosyl bond stability

scientific article

Vinylogous amide analogs of methylphenidate

scientific article

X-ray crystallography of chemical compounds.

scientific article

X-ray studies on ligands

scientific article published on 01 January 2002

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