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List of works by David H. Ellison

A SPAK isoform switch modulates renal salt transport and blood pressure

scientific journal article

A quest--halting the progression of autosomal dominant polycystic kidney disease

scientific article published on 15 November 2014

Adaptation in Gitelman syndrome: "we just want to pump you up"

scientific article published on 16 February 2012

Advancing Nephrology: Division Leaders Advise ASN

scientific article published on 12 August 2020

Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway.

scientific article published on 17 August 2009

Altered renal FGF23-mediated activity involving MAPK and Wnt: effects of the Hyp mutation

scientific article

Calcineurin and Sorting-Related Receptor with A-Type Repeats Interact to Regulate the Renal Na⁺-K⁺-2Cl⁻ Cotransporter

scientific article

Calcineurin inhibitor cyclosporine A activates renal Na-K-Cl cotransporters via local and systemic mechanisms

scientific article published on 21 December 2016

Clinical practice. The syndrome of inappropriate antidiuresis.

scientific article

Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension

scientific article

Distal convoluted tubule

scientific article

Distal convoluted tubule.

scientific article published in January 2015

Diuretic Resistance.

scientific article

Diuretic drugs and the treatment of edema: from clinic to bench and back again

scientific article published on May 1994

Diuretic therapy and resistance in congestive heart failure

scientific article published in January 2001

Diuretics and salt transport along the nephron

scientific article

Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform

scientific journal article

Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension

scientific article published on 13 June 2018

Enemy Action in the Distal Convoluted Tubule

scientific article published on 08 July 2019

Enhanced phosphorylation of Na(+)-Cl- co-transporter in experimental metabolic syndrome: role of insulin

scientific article published on December 2012

Evaluating hyponatremia

scientific article

Gitelman syndrome: consensus and guidance from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

scientific article

Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter

scientific article

High tail-cuff blood pressure in mice 1 week after shipping: the need for longer acclimation

scientific article published on 3 February 2011

Hyperkalemia and trimethoprim-sulfamethoxazole

scientific article published on 01 June 1997

Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3

scientific article

Hypertension after kidney transplantation: calcineurin inhibitors increase salt-sensitivity

scientific article published on 01 April 2012

Hypertension-causing cullin 3 mutations disrupt COP9 signalosome binding

scientific article published on 09 December 2019

Improved graft survival after renal transplantation in the United States, 1988 to 1996

scientific article published on 01 June 2000

Infusion of bovine parathyroid hormone1-34 attenuates the pressor response to angiotensin II in spontaneously hypertensive rats.

scientific article

Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter

scientific journal article

Kidney Is Essential for Blood Pressure Modulation by Dietary Potassium

scientific article published on 13 August 2020

Kidney-specific WNK1 isoform (KS-WNK1) is a potent activator of WNK4 and NCC.

scientific article

Kir4.1/Kir5.1 in the DCT plays a role in the regulation of renal K+ excretion

scientific article published on 09 January 2019

Management of cirrhotic ascites: physiological basis of diuretic action

scientific article

Mechanistic Insights into Loop Diuretic Responsiveness in Heart Failure

scientific article published on 22 April 2019

Osmotic activity of dimethyl sulfoxide in the renal distal tubule

scientific article published on 01 October 1984

Outstanding translational science at American Society of Hypertension 2015.

scientific article published on 8 September 2015

Pathophysiology of functional mutations of the thiazide-sensitive Na-Cl cotransporter in Gitelman disease

scientific article

Patients with hypokalemia develop WNK bodies in the distal convoluted tubule of the kidney

scientific article published on 28 November 2018

Potassium and Its Discontents: New Insight, New Treatments

scientific article published on 28 October 2015

Potassium modulates electrolyte balance and blood pressure through effects on distal cell voltage and chloride

scientific article

Protein phosphatase 1 inhibitor-1 deficiency reduces phosphorylation of renal NaCl cotransporter and causes arterial hypotension

scientific article

Rabbit distal convoluted tubule coexpresses NaCl cotransporter and 11 beta-hydroxysteroid dehydrogenase II mRNA.

scientific article

Regulation of Renal Electrolyte Transport by WNK and SPAK-OSR1 Kinases.

scientific article published on February 2016

Renal Deletion of 12 kDa FK506-Binding Protein Attenuates Tacrolimus-Induced Hypertension.

scientific article published on 2 October 2015

Renal mineralocorticoid receptor and electrolyte homeostasis

scientific article published on July 2015

Renal nerves, WNK4, glucocorticoids, and salt transport

scientific article published on June 2011

Renal tubular resistance is the primary driver for loop diuretic resistance in acute heart failure.

scientific article published on 19 January 2017

Renal-Tubule Epithelial Cell Nomenclature for Single-Cell RNA-Sequencing Studies ⬇️

scientific article published on 28 June 2019

SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na(+)-K(+)-Cl(-) cotransporter 2.

scientific article

SPAK differentially mediates vasopressin effects on sodium cotransporters.

scientific article published on 7 February 2013

Salt sensitivity: a review with a focus on non-Hispanic blacks and Hispanics

scientific article

Salt-sensitive transcriptome of isolated kidney distal tubule cells

scientific article published on 15 March 2019

Separate and interacting effects of the endogenous circadian system and behaviors on plasma aldosterone in humans

scientific article published on 06 December 2018

Sorting out lysosomal trafficking of the thiazide-sensitive Na-Cl Co-transporter.

scientific article

Sympathetic stimulation of thiazide-sensitive sodium chloride cotransport in the generation of salt-sensitive hypertension.

scientific article

Tacrolimus-induced hypomagnesemia and hypercalciuria requires FKBP12 suggesting a role for calcineurin

scientific article published on 01 January 2020

The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway

scientific article published on 30 May 2018

The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride

scientific article published on 26 December 2014

The WNK kinase network regulating sodium, potassium, and blood pressure

scientific article published on 24 March 2011

The WNKs: atypical protein kinases with pleiotropic actions.

scientific article

The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension

scientific article

The physiologic basis of diuretic synergism: its role in treating diuretic resistance

scientific article published on May 1991

The voltage-gated K+ channel subunit Kv1.1 links kidney and brain

scientific article published on April 2009

Thiazide effects and adverse effects: insights from molecular genetics

scientific article published on 29 June 2009

Through a glass darkly: salt transport by the distal tubule

scientific article published on January 2011

Training the next generation's nephrology workforce.

scientific article

Treatment of Disorders of Sodium Balance in Chronic Kidney Disease

scientific article published in September 2017

Ubiquitylation and the pathogenesis of hypertension

scientific article published on 25 January 2013

Unique chloride-sensing properties of WNK4 permit the distal nephron to modulate potassium homeostasis

scientific article

WNK Kinase Signaling in Ion Homeostasis and Human Disease.

scientific article published on February 2017

WNK bodies cluster WNK4 and SPAK/OSR1 to promote NCC activation in hypokalemia

scientific article published on 18 November 2019

WNK kinases and the kidney

scientific article published on 03 March 2012

WNK kinases regulate sodium chloride and potassium transport by the aldosterone-sensitive distal nephron

scientific article

WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.

scientific article published on 11 August 2014

WNK1 and WNK4 modulate CFTR activity

scientific article published on 15 December 2006

WNK1 kinase isoform switch regulates renal potassium excretion.

scholarly article

WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction

scientific article published on 28 April 2009

Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule

scientific article published on 10 September 2006

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