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List of works by Stephan A. Pless

A Cation-π Interaction at a Phenylalanine Residue in the Glycine Receptor Binding Site Is Conserved for Different Agonists ⬇️

scientific article published on January 25, 2011

A Conserved Residue Cluster That Governs Kinetics of ATP-dependent Gating of Kir6.2 Potassium Channels

scientific article published in May 2015

A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel.

scientific article published on January 2013

A selectivity filter at the intracellular end of the acid-sensing ion channel pore

scientific article

Acid-sensing ion channels emerged over 600 Mya and are conserved throughout the deuterostomes

scientific article published on 30 July 2018

Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains

scientific article published on May 2014

Atom-by-atom engineering of voltage-gated ion channels: magnified insights into function and pharmacology

scientific article

Atomic basis for therapeutic activation of neuronal potassium channels

scientific article

Caught in the act: multiple binding sites for memantine

scientific article published on 01 October 2014

Chemical modification of proteins by insertion of synthetic peptides using tandem protein trans-splicing

scientific article published on 08 May 2020

Conformational variability of the glycine receptor M2 domain in response to activation by different agonists

scientific article published on 2 October 2007

Contributions of conserved residues at the gating interface of glycine receptors.

scientific article

Contributions of counter-charge in a potassium channel voltage-sensor domain.

scientific article published on 24 July 2011

Determinants of ion selectivity in ASIC1a- and ASIC2a-containing acid-sensing ion channels

scientific article published on 01 February 2020

Distinct conformational changes in activated agonist-bound and agonist-free glycine receptor subunits

scientific article published on 24 January 2009

Evolutionarily Conserved Interactions within the Pore Domain of Acid-Sensing Ion Channels

scientific article published on 06 September 2019

Expression-dependent pharmacology of transient receptor potential vanilloid subtype 1 channels in Xenopus laevis oocytes

scientific article published on January 2013

Extracellular quaternary ammonium blockade of transient receptor potential vanilloid subtype 1 channels expressed in Xenopus laevis oocytes.

scientific article published on 6 September 2012

Four drug-sensitive subunits are required for maximal effect of a voltage sensor-targeted KCNQ opener

scientific article published on 30 August 2018

Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5

scientific article

High-Sensitivity Fluorometry to Resolve Ion Channel Conformational Dynamics.

scientific article published in February 2018

How an intrinsic ligand tunes the activity of a potassium channel

scientific article published on 22 March 2018

Hydrogen bonds as molecular timers for slow inactivation in voltage-gated potassium channels

scientific article published on 10 December 2013

Intermediate state trapping of a voltage sensor

scientific article

Introduction: Applying Chemical Biology to Ion Channels

scientific article published on 01 January 2015

Investigation of Agonist Recognition and Channel Properties in a Flatworm Glutamate-Gated Chloride Channel.

scientific article published on 7 February 2018

Ligand- and Subunit-specific Conformational Changes in the Ligand-binding Domain and the TM2-TM3 Linker of α1 β2 γ2 GABAA Receptors ⬇️

scientific article published on October 11, 2010

Ligand-specific conformational changes in the alpha1 glycine receptor ligand-binding domain

scientific article published on 13 March 2009

Magnitude of a conformational change in the glycine receptor beta1-beta2 loop is correlated with agonist efficacy

scientific article published on 30 July 2009

Mechanism and site of action of big dynorphin on ASIC1a

scientific article published on 12 March 2020

Molecular Basis for Allosteric Inhibition of Acid-Sensing Ion Channel 1a by Ibuprofen.

scientific article

Molecular basis for class Ib anti-arrhythmic inhibition of cardiac sodium channels

scientific article published on 14 June 2011

Molecular determinants for agonist recognition and discrimination in P2X2 receptors

scientific article published on 24 May 2019

One drug-sensitive subunit is sufficient for a near-maximal retigabine effect in KCNQ channels.

scientific article published on 30 August 2018

PIP2 mediates functional coupling and pharmacology of neuronal KCNQ channels

scientific article published on 23 October 2017

Peptide Inhibitors of the α-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction

scientific article published on 03 November 2020

Phenotypic Spectrum of HCN4 Mutations: A Clinical Case

scientific article published on 01 February 2018

Principles of agonist recognition in Cys-loop receptors

scientific article (publication date: 2014)

Role of an Absolutely Conserved Tryptophan Pair in the Extracellular Domain of Cys-Loop Receptors

scientific article published on 29 January 2016

Structure of the human sodium leak channel NALCN

scientific article published on 22 July 2020

The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium

scientific article published on 24 April 2020

The current chemical biology tool box to study ion channels

scientific article published on 26 July 2020

The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro

scientific article published in June 2011

Unexplained cardiac arrest: a tale of conflicting interpretations of KCNQ1 genetic test results

scientific article published on 26 March 2018

Unique Contributions of an Arginine Side Chain to Ligand Recognition in a Glutamate-gated Chloride Channel

scientific article published on 17 January 2017

Unnatural amino acids as probes of ligand-receptor interactions and their conformational consequences.

scientific article published on January 2013

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