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List of works by Youngjae You

(E) -6-(1-alkyloxyiminoalkyl)-5,8-dimethoxy-1,4-naphthoquinones: synthesis, cytotoxic activity and antitumor activity.

scientific article

2-cyano-lup-1-en-3-oxo-20-oic acid, a cyano derivative of betulinic acid, activates peroxisome proliferator-activated receptor gamma in colon and pancreatic cancer cells

scientific article published on 27 August 2007

Alkyl and carboxylalkyl esters of 4'-demethyl-4-deoxypodophyllotoxin: synthesis, cytotoxic, and antitumor activity

scientific article published on February 2004

Antiangiogenic activity of lupeol from Bombax ceiba

scientific article published in April 2003

Anticancer drug released from near IR-activated prodrug overcomes spatiotemporal limits of singlet oxygen

scientific article published on 21 February 2016

Antitumor activity of unsaturated fatty acid esters of 4'-demethyldeoxypodophyllotoxin

scientific article published in August 2003

Asymmetric ZnPc-rhodamine B conjugates for mitochondrial targeted photodynamic therapy

scientific article published on 07 August 2014

Click and photo-unclick chemistry of aminoacrylate for visible light-triggered drug release

scientific article published on 23 May 2012

Combretoxazolones: synthesis, cytotoxicity and antitumor activity

article published in 2001

Core-modified porphyrins. Part 5: Electronic effects on photophysical and biological properties in vitro

scientific article published in November 2005

Core-modified porphyrins. Part 6: Effects of lipophilicity and core structures on physicochemical and biological properties in vitro

scientific article published on 27 December 2007

Crystal structures of glutathione- and inhibitor-bound human GGT1: Critical interactions within the cysteinylglycine binding site

scientific article published on 13 November 2020

Cytotoxic 2',5'-dihydroxychalcones with unexpected antiangiogenic activity

scientific article published in February 2003

Deoxypodophyllotoxin; the cytotoxic and antiangiogenic component from Pulsatilla koreana

scientific article published in March 2002

Dithiaporphyrin derivatives as photosensitizers in membranes and cells.

scientific article

Dual Functioning Thieno-Pyrrole Fused BODIPY Dyes for NIR Optical Imaging and Photodynamic Therapy: Singlet Oxygen Generation without Heavy Halogen Atom Assistance

scientific article published on 23 April 2015

Efficient activation of a visible light-activatable CA4 prodrug through intermolecular photo-unclick chemistry in mitochondria.

scientific article published on 23 January 2017

Enhanced singlet oxygen generation from a porphyrin-rhodamine B dyad by two-photon excitation through resonance energy transfer

scientific article published on 5 April 2013

Esters of 2-(1-hydroxyalkyl)-1,4-dihydroxy-9,10-anthraquinones with melphalan as multifunctional anticancer agents

scientific article

Esters of chlorambucil with 2-substituted 1,4-dihydroxy-9,10-anthraquinones as multifunctional anticancer agents

scientific article published in April 2001

Evaluation of delocalized lipophilic cationic dyes as delivery vehicles for photosensitizers to mitochondria

scientific article

Far-Red Light-Activatable Prodrug of Paclitaxel for the Combined Effects of Photodynamic Therapy and Site-Specific Paclitaxel Chemotherapy

scientific article published on 14 March 2016

Far-red light activatable, multifunctional prodrug for fluorescence optical imaging and combinational treatment

scientific article published on 14 April 2014

Folate receptor-mediated enhanced and specific delivery of far-red light-activatable prodrugs of combretastatin A-4 to FR-positive tumor

scientific article

Folate-PEG Conjugates of a Far-Red Light-Activatable Paclitaxel Prodrug to Improve Selectivity toward Folate Receptor-Positive Cancer Cells.

scientific article published on 4 October 2017

Identification of novel drugs to target dormant micrometastases

scientific article

In vitro and in vivo photodynamic activity of core-modified porphyrin IY69 using 690 nm diode laser.

scientific article

Inhibitory effect of Adonis amurensis components on tube-like formation of human umbilical venous cells

scientific article published on May 2003

Local and Systemic Antitumor Effects of Photo-activatable Paclitaxel Prodrug on Rat Breast Tumor Models

scientific article published on 28 December 2019

Mechanistic studies of the tellurium(II)/tellurium(IV) redox cycle in thiol peroxidase-like reactions of diorganotellurides in methanol

scientific article published in April 2003

Naphthazarin derivatives (II): formation of glutathione conjugate, inhibition of DNA topoisomerase-I and cytotoxicity

scientific article published on 01 August 1999

Naphthazarin derivatives (IV): synthesis, inhibition of DNA topoisomerase I and cytotoxicity of 2- or 6-acyl-5,8-dimethoxy-1, 4-naphthoquinones

scientific article published on 01 March 2000

Naphthazarin derivatives (VI): synthesis, inhibitory effect on DNA topoisomerase-I and antiproliferative activity of 2- or 6-(1-oxyiminoalkyl)-5,8-dimethoxy-1,4-naphthoquinones

scientific article published on 01 April 2000

Naphthazarin derivatives (VIII): Synthesis, inhibitory effect on DNA topoisomerase-I, and antiproliferative activity of 6-(1-acyloxyalkyl)-5,8-dimethoxy-1,4-naphthoquinones

scientific article published in October 2001

New constituents from Crinum latifolium with inhibitory effects against tube-like formation of human umbilical venous endothelial cells.

scientific article

Photodynamic therapy via FRET following bioorthogonal click reaction in cancer cells

scientific article published on 10 November 2015

Phototoxicity of a core-modified porphyrin and induction of apoptosis

scientific article published on 14 August 2006

Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents

scientific article

Polymer photovoltaics from all-water-solution processing

Preliminary structure-antiangiogenic activity relationships of 4-senecioyloxymethyl-6,7-dimethoxycoumarin

scientific article published in September 2002

Prodrugs of 4'-demethyl-4-deoxypodophyllotoxin: synthesis and evaluation of the antitumor activity

scientific article published in December 2002

Quantitative modeling of the dynamics and intracellular trafficking of far-red light-activatable prodrugs: implications in stimuli-responsive drug delivery system.

scientific article

SAR of L-ABBA analogs for GGT1 inhibitory activity and L-ABBA's effect on plasma cysteine and GSH species

scientific article published in 2023

Singlet oxygen generation by novel NIR BODIPY dyes

scientific article published on 06 July 2011

Singlet oxygen-activatable Paclitaxel prodrugs via intermolecular activation for combined PDT and chemotherapy

scientific article published on 02 April 2019

Site-specific and far-red-light-activatable prodrug of combretastatin A-4 using photo-unclick chemistry.

scientific article

Stimulation of P-glycoprotein ATPase by analogues of tetramethylrosamine: coupling of drug binding at the "R" site to the ATP hydrolysis transition state

scientific article published in July 2006

Structure-activity studies of uptake and phototoxicity with heavy-chalcogen analogues of tetramethylrosamine in vitro in chemosensitive and multidrug-resistant cells.

scientific article

Syntheses of certain 3-aryl-2-propenoates and evaluation of their cytotoxicity

scientific article

Synthesis and anti-tumor activity of novel combretastatins: combretocyclopentenones and related analogues

scientific article

Synthesis and cytotoxic activity of A-ring modified betulinic acid derivatives

scientific article published on October 2003

Synthesis and cytotoxicity of 3,4-diaryl-2(5H)-furanones

scientific article published in February 2002

Synthesis and in vitro biological evaluation of lipophilic cation conjugated photosensitizers for targeting mitochondria

scientific article published on 3 December 2012

Synthesis and singlet oxygen reactivity of 1,2-diaryloxyethenes and selected sulfur and nitrogen analogs

scientific article published on 21 February 2012

Thieno-pyrrole-fused 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-fullerene dyads: utilization of near-infrared sensitizers for ultrafast charge separation in donor-acceptor systems

scientific article published on 15 May 2014

Thieno-pyrrole-fused BODIPY intermediate as a platform to multifunctional NIR agents

scientific article

Visible Light Controlled Release of Anticancer Drug through Double Activation of Prodrug

scientific article

Water soluble prodrugs of the antitumor agent 3-[(3-amino-4-methoxy)phenyl]-2-(3,4,5-trimethoxyphenyl)cyclopent-2-ene-1-one.

scientific article