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List of works by Helena E. Richardson

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Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation

scientific article published in April 1994
scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila

scientific article
A family of cyclin homologs that control the G1 phase in yeast

scientific article
Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms

scientific article published in April 2010
Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2

scientific article published on November 1, 1992
A cyclin B homolog in S. cerevisiae: Chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis

scientific article published on April 5, 1991
DRONC, an ecdysone-inducible Drosophila caspase

scientific article
Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module

scientific article
Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis

scientific article published in June 1995
Upstream regulation of the hippo size control pathway

scientific article published on July 2010
Using Drosophila melanogaster to map human cancer pathways

scientific article
The Drosophila Geminin homolog: roles for Geminin in limiting DNA replication, in anaphase and in neurogenesis

scientific article
An essential role for the caspase dronc in developmentally programmed cell death in Drosophila

scientific article published in December 2000
The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster

scientific article
Debcl, a proapoptotic Bcl-2 homologue, is a component of the Drosophila melanogaster cell death machinery.

scientific article
DECAY, a novel Drosophila caspase related to mammalian caspase-3 and caspase-7.

scientific article published in October 1999
Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions

scientific article
The Scribble-Dlg-Lgl polarity module in development and cancer: from flies to man.

scientific article published on January 2012
Death to flies: Drosophila as a model system to study programmed cell death

scientific article
APC/CFzr/Cdh1 promotes cell cycle progression during the Drosophila endocycle

scientific article
The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy

scientific article
hScrib is a functional homologue of the Drosophila tumour suppressor Scribble

scientific article (publication date: 18 December 2003)
Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling

scientific article
An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery.

scientific article published on 20 September 2012
Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye.

scientific article
Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs

scientific article published on 24 September 2009
Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis

scientific article
Characterization of the Drosophila caspase, DAMM.

scientific article published on 3 May 2001
The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages

scientific article published on 11 March 2014
STRICA, a novel Drosophila melanogaster caspase with an unusual serine/threonine-rich prodomain, interacts with DIAP1 and DIAP2.

scientific article
A fission yeast B-type cyclin functioning early in the cell cycle

scientific article published on July 12, 1991
Drosophila cyclin E interacts with components of the Brahma complex

scientific article
Dominant negative protein kinase mutations that confer a G1 arrest phenotype

scientific article
A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila.

scientific article
Lgl, the SWH pathway and tumorigenesis: It's a matter of context & competition!

scientific article published on 10 August 2010
Lgl/aPKC and Crb regulate the Salvador/Warts/Hippo pathway

scientific article published on 21 October 2010
Drosophila Hfp negatively regulates dmyc and stg to inhibit cell proliferation

scientific article published in March 2004
The Ecdysone-inducible zinc-finger transcription factor Crol regulates Wg transcription and cell cycle progression in Drosophila

scientific article published on 9 July 2008
Hfp inhibits Drosophila myc transcription and cell growth in a TFIIH/Hay-dependent manner

scientific article
The BTB-zinc finger transcription factor abrupt acts as an epithelial oncogene in Drosophila melanogaster through maintaining a progenitor-like cell state

scientific article (publication date: 2013)
Tissue growth and tumorigenesis in Drosophila: cell polarity and the Hippo pathway.

scientific article published on 28 March 2017
Lgl regulates Notch signaling via endocytosis, independently of the apical aPKC-Par6-Baz polarity complex.

scientific article published on 11 September 2014
The Scribble Cell Polarity Module in the Regulation of Cell Signaling in Tissue Development and Tumourigenesis.

scientific article published on 30 January 2018
BTB-Zinc Finger Oncogenes Are Required for Ras and Notch-Driven Tumorigenesis in Drosophila.

scientific article published on 24 July 2015
Analysis of Drosophila cyclin EI and II function during development: identification of an inhibitory zone within the morphogenetic furrow of the eye imaginal disc that blocks the function of cyclin EI but not cyclin EII.

scientific article published in January 2002
Geminin and Brahma act antagonistically to regulate EGFR-Ras-MAPK signaling in Drosophila.

scientific article published on 21 April 2010
Death takes a holiday--non-apoptotic role for caspases in cell migration and invasion.

scientific article published on 15 January 2013
Regulation of Notch signaling and endocytosis by the Lgl neoplastic tumor suppressor.

scientific article
When cell cycle meets development

scientific article
POSH regulates Hippo signaling through ubiquitin-mediated expanded degradation

scientific article published on 12 February 2018

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