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List of works by Brian D Evavold

A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells

scientific article published on 13 December 2019

A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery

scientific article published on 05 December 2019

A cytokine promoter/yellow fluorescent protein reporter transgene serves as an early activation marker of lymphocyte subsets.

scientific article published in October 2005

A unique unresponsive CD4+ T cell phenotype post TCR antagonism

scientific article published on 23 December 2009

Accessory cell function of Th2 clones

scientific article published in September 1989

Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling.

scientific article published on April 2014

Accumulation of serial forces on TCR and CD8 frequently applied by agonist antigenic peptides embedded in MHC molecules triggers calcium in T cells

scientific article

Amelioration of established experimental autoimmune encephalomyelitis by an MHC anchor-substituted variant of proteolipid protein 139-151.

scientific article published on March 2005

An MHC anchor-substituted analog of myelin oligodendrocyte glycoprotein 35-55 induces IFN-gamma and autoantibodies in the absence of experimental autoimmune encephalomyelitis and optic neuritis

scientific article published on 01 February 2004

Antigenicity of passively acquired major histocompatibility antigens on T cells

scientific article published on 01 July 1988

CD4 T Cell Affinity Diversity Is Equally Maintained during Acute and Chronic Infection

scientific article published on 18 May 2018

CD43 modulates severity and onset of experimental autoimmune encephalomyelitis

scientific article published on 01 December 2003

CD8+ T cell responses to a viral escape mutant epitope: active suppression via altered SHP-1 activity

scientific article published in February 2009

CIITA promoter I CARD-deficient mice express functional MHC class II genes in myeloid and lymphoid compartments

scientific article published on January 5, 2012

Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.

scientific article

Complete dissection of the Hb(64-76) determinant using T helper 1, T helper 2 clones, and T cell hybridomas

scientific article published on 01 January 1992

Conserved Region C Functions To Regulate PD-1 Expression and Subsequent CD8 T Cell Memory.

scientific article published on 28 November 2016

Conserved T Cell Receptor Repertoire in Primary and Memory CD8 T Cell Responses to an Acute Viral Infection

scientific article published on July 6, 1998

Correction to: Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells.

scientific article published on 20 December 2017

Cutting Edge: Resident Memory CD8 T Cells Express High-Affinity TCRs

scientific article

Cutting edge: dependence of TCR antagonism on Src homology 2 domain-containing protein tyrosine phosphatase activity

scientific article published in May 2003

Cutting edge: dueling TCRs: peptide antagonism of CD4+ T cells with dual antigen specificities.

scientific article published on August 1999

DNA-based nanoparticle tension sensors reveal that T-cell receptors transmit defined pN forces to their antigens for enhanced fidelity

scientific article

DO11.10 and OT-II T cells recognize a C-terminal ovalbumin 323-339 epitope

scientific article published on 01 May 2000

Defining the parameters necessary for T-cell recognition of ligands that vary in potency.

scientific article published on January 2004

Degenerate recognition of T cell epitopes: impact of T cell receptor reserve and stability of peptide:MHC complexes.

scientific article published on February 2004

Delayed antigen presentation by epidermal Langerhans cells to cloned T h1 and T h2 cells

scientific article published in October 1990

Destabilization of peptide:MHC interaction induces IL-2 resistant anergy in diabetogenic T cells

scientific article published on 26 July 2013

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells.

scientific article

Direct activation of murine resting T cells by con A or anti-CD3 Ig.

scientific article published on January 1989

Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes

scientific article published on 21 August 2019

Dissection of the Hb(64-76) determinant reveals that the T cell receptor may have the capacity to differentially signal.

scientific article published on January 1992

Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.

scientific article published on 10 November 2017

Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM

scientific journal article

Estimating the diversity, completeness, and cross-reactivity of the T cell repertoire

scientific article

Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells.

scientific article

High prevalence of low affinity peptide–MHC II tetramer–negative effectors during polyclonal CD4+ T cell responses

scientific article published on January 10, 2011

IL-21 from high-affinity CD4 T cells drives differentiation of brain-resident CD8 T cells during persistent viral infection

scientific article published on 01 September 2020

Identification of T cell clones without the need for sequencing.

scientific article

Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

scientific article published in Nature

Induction of anergy by antibody blockade of TCR in myelin oligodendrocyte glycoprotein-specific cells

scientific article published on 01 June 2008

Insights from in situ analysis of TCR-pMHC recognition: response of an interaction network

scientific article published on January 2013

Insights into T cell recognition of antigen: significance of two-dimensional kinetic parameters

scientific article published on 20 April 2012

Kinetics of MHC-CD8 interaction at the T cell membrane.

scientific article published in December 2007

Loss of IFN-gamma enables the expansion of autoreactive CD4+ T cells to induce experimental autoimmune encephalomyelitis by a nonencephalitogenic myelin variant antigen

scientific article published on 01 April 2008

Low 2-dimensional CD4 T cell receptor affinity for myelin sets in motion delayed response kinetics

scientific article

Low-Affinity Memory CD8+ T Cells Mediate Robust Heterologous Immunity.

scientific article published on 10 February 2016

Low-affinity CD4+ T cells are major responders in the primary immune response

scientific article published on 15 December 2016

Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response

scientific article

MHC Bias by T Cell Receptors: Genetic Evidence for MHC and TCR Coevolution.

scientific article published on 8 December 2016

MHC variant peptide-mediated anergy of encephalitogenic T cells requires SHP-1.

scientific article published in November 2008

Modification of peptide interaction with MHC creates TCR partial agonists

scientific article

Modulation of MOG 37-50-specific CD8+ T cell activation and expansion by CD43

scientific article published on 01 March 2006

Modulation of T cell development by an endogenous altered peptide ligand

scientific article

NFM Cross-Reactivity to MOG Does Not Expand a Critical Threshold Level of High-Affinity T Cells Necessary for Onset of Demyelinating Disease

scientific article

Pathogenic MOG-reactive CD8+ T cells require MOG-reactive CD4+ T cells for sustained CNS inflammation during chronic EAE.

scientific article published on 21 June 2009

Peptide immunization elicits polyomavirus-specific MHC class ib-restricted CD8 T cells in MHC class ia allogeneic mice.

scientific article published on February 2013

Persistence of peptide-induced CD4+ T cell anergy in vitro

scientific article published in January 1998

Pillars article: separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand. Science. 1991. 252: 1308-1310.

scientific article published in January 2011

Production of IL-2 and IFN by TH2 clones

scientific article published on 01 May 1989

Progression of relapsing-remitting demyelinating disease does not require increased TCR affinity or epitope spread

scientific article

Ratiometric Tension Probes for Mapping Receptor Forces and Clustering at Intermembrane Junctions.

scientific article published on 18 May 2016

Regulation of polyclonal T cell responses by an MHC anchor-substituted variant of myelin oligodendrocyte glycoprotein 35-55.

scientific article published in August 2003

Regulatory B Cells Induce Formation of IL-10-Expressing T Cells in Mice with Autoimmune Neuroinflammation.

scientific article

Regulatory and T Effector Cells Have Overlapping Low to High Ranges in TCR Affinities for Self during Demyelinating Disease

scientific article

Self-reactive human CD4 T cell clones form unusual immunological synapses

scientific article published on 6 February 2012

Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand

scientific article

Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides

scientific article published on 01 April 1993

Specific T cell recognition of minimally homologous peptides: evidence for multiple endogenous ligands

scientific article published on June 1995

Specificity, magnitude, and kinetics of MOG-specific CD8+ T cell responses during experimental autoimmune encephalomyelitis

scientific article published on 01 January 2005

Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response.

scientific article published on 5 January 2016

Stimulation of peripheral blood T cells by an activated T-cell line: a novel human autologous T-T lymphocyte reaction

scientific article published on December 1991

Sustained Rap1 activation in autoantigen-specific T lymphocytes attenuates experimental autoimmune encephalomyelitis

scientific article published on 10 June 2012

T Cell Receptor-Major Histocompatibility Complex Interaction Strength Defines Trafficking and CD103+ Memory Status of CD8 T Cells in the Brain.

scientific article

T cell inducing determinants contain a hierarchy of residues contacting the T cell receptor

scientific article published on July 1, 1991

T cell recognition of weak ligands: roles of signaling, receptor number, and affinity

scientific article

T helper 2 (Th2) but not Th1 clones co-stimulate resting T cells in the presence of anti-CD3 monoclonal antibody

scientific article published on 01 January 1989

TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.

scientific article

TCR antagonism by peptide requires high TCR expression

scientific article published on 01 August 2008

TCR reserve: a novel principle of CD4 T cell activation by weak ligands

scientific article published on February 2003

Targeted loss of SHP1 in murine thymocytes dampens TCR signaling late in selection

scientific article published on 29 June 2016

Targeting transcriptional coregulator OCA-B/Pou2af1 blocks activated autoreactive T cells in the pancreas and type 1 diabetes

scientific article published on 01 March 2021

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness.

scientific article

The processing and presentation of the self-antigen hemoglobin. Self-reactivity can be limited by antigen availability and costimulator expression

scientific article published on 01 November 1991

The syngeneic T-T lymphocyte reaction (STTLR). I. Induction of primary T anti-T cell proliferative responses in T cell cultures stimulated with self- and antigen-reactive T cells.

scientific article published on January 1986

Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands

scientific article published on December 1993

Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity.

scientific article published on March 2009

Two-Stage Cooperative T Cell Receptor-Peptide Major Histocompatibility Complex-CD8 Trimolecular Interactions Amplify Antigen Discrimination

scientific article (publication date: 28 January 2011)

Viral Escape Mutant Epitope Maintains TCR Affinity for Antigen yet Curtails CD8 T Cell Responses

scientific article