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List of works by Scott C Blanchard

A Much-Needed Boost for the Dwindling Antibiotic Pipeline.

scientific article published in April 2018

A facile approach for the in vitro assembly of multimeric membrane transport proteins.

scientific article

A fast dynamic mode of the EF-G-bound ribosome.

scientific article

A new view of protein synthesis: mapping the free energy landscape of the ribosome using single-molecule FRET.

scientific article

A partially-open inward-facing intermediate conformation of LeuT is associated with Na+ release and substrate transport.

scientific article published on 15 January 2018

A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS

scientific article published on 03 September 2019

ADAM10 controls the differentiation of the coronary arterial endothelium

scientific article published on 16 November 2018

Allosteric control of the ribosome by small-molecule antibiotics.

scientific article

Aminoglycoside interactions and impacts on the eukaryotic ribosome.

scientific article published on 5 December 2017

Approaching translation at atomic resolution.

scientific article

Assembly and diploid architecture of an individual human genome via single-molecule technologies

scientific article published on 29 June 2015

Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET

scientific article published on 10 April 2019

Breaking the barriers of translation

scientific article published on May 2008

Cargo adaptors regulate stepping and force generation of mammalian dynein-dynactin

scientific article published on 09 September 2019

Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions

scientific article published on 30 July 2015

Conformational capture of the SAM-II riboswitch

scientific article

Conformational dynamics between transmembrane domains and allosteric modulation of a metabotropic glutamate receptor.

scientific article

Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

scientific article

Conformational sampling of aminoacyl-tRNA during selection on the bacterial ribosome.

scientific article

Connecting the kinetics and energy landscape of tRNA translocation on the ribosome

scientific article

Correction to: Implications of sequence variation on the evolution of rRNA

scientific article published on 01 September 2019

Cryoelectron microscopy structures of the ribosome complex in intermediate states during tRNA translocation

scientific article

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

scientific article

Cyanine fluorophore derivatives with enhanced photostability

scientific article published on 13 November 2011

Direct Detection of α-Synuclein Dimerization Dynamics: Single-Molecule Fluorescence Analysis

scientific article published on April 2015

Direct evidence of an elongation factor-Tu/Ts·GTP·Aminoacyl-tRNA quaternary complex.

scientific article

Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements

scientific article published on 24 January 2020

Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A

scientific article published on 28 May 2015

Dynamics of P-type ATPase transport revealed by single-molecule FRET.

scientific article published on 8 November 2017

ERASE: a novel surface reconditioning strategy for single-molecule experiments

scientific article published on 01 February 2019

Effect of acidic pH on the stability of α-synuclein dimers

scientific article published on 14 May 2016

Electronic tuning of self-healing fluorophores for live-cell and single-molecule imaging.

scientific article published on 07 September 2016

Elongation Factor Ts Directly Facilitates the Formation and Disassembly of the Escherichia coli Elongation Factor Tu·GTP·Aminoacyl-tRNA Ternary Complex ⬇️

scientific article published on March 28, 2013

Elongation factor-Tu can repetitively engage aminoacyl-tRNA within the ribosome during the proofreading stage of tRNA selection

scientific article published on 05 February 2020

Engineering a Prototypic P-type ATPase Listeria monocytogenes Ca(2+)-ATPase 1 for Single-Molecule FRET Studies.

scientific article published on 8 August 2016

Enhanced photostability of cyanine fluorophores across the visible spectrum ⬇️

scientific article published on April 27, 2012

Folding and ligand recognition of the TPP riboswitch aptamer at single-molecule resolution.

scientific article

Functional Dynamics within the Human Ribosome Regulate the Rate of Active Protein Synthesis.

scientific article

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

scientific article

Genome Sequence and Analysis of Escherichia coli MRE600, a Colicinogenic, Nonmotile Strain that Lacks RNase I and the Type I Methyltransferase, EcoKI

scientific article published on 22 January 2016

HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations

scientific article published on 21 March 2018

High-resolution structure of the Escherichia coli ribosome.

scientific article published on 16 March 2015

Identification of two distinct hybrid state intermediates on the ribosome

scientific article

Implications of sequence variation on the evolution of rRNA

scientific article published on 05 February 2019

Insights into the molecular determinants of EF-G catalyzed translocation.

scientific article published on 27 October 2011

Intra-molecular triplet energy transfer is a general approach to improve organic fluorophore photostability

scientific article published on 23 December 2015

Mechanistic insights into antibiotic action on the ribosome through single‐molecule fluorescence imaging ⬇️

scientific article published on December 1, 2011

Miscoding-induced stalling of substrate translocation on the bacterial ribosome

scientific article published on 25 September 2017

Multiperspective smFRET reveals rate-determining late intermediates of ribosomal translocation.

scientific article published on 29 February 2016

Navigating the ribosome's metastable energy landscape

scientific article

Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome

scientific article

On the Mechanisms of Cyanine Fluorophore Photostabilization.

scientific article

Pseudoknot Formation Seeds the Twister Ribozyme Cleavage Reaction Coordinate

scientific article published on 09 June 2017

Publisher Correction: The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions.

scientific article published on 8 January 2018

Quantifying secondary transport at single-molecule resolution

scientific article published on 13 November 2019

Quantitative comparison between sub-millisecond time resolution single-molecule FRET measurements and 10-second molecular simulations of a biosensor protein

scientific article published on 05 November 2020

Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles

scientific article

Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles

scientific article published on 13 September 2020

Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins

scientific article published on 25 October 2016

Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors

scientific article published on 05 July 2016

Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease

scientific article published on 08 May 2019

Single-molecule analysis of ligand efficacy in β2AR-G-protein activation

scientific article published on 07 June 2017

Single-molecule dynamics of gating in a neurotransmitter transporter homologue

scientific article

Single-molecule imaging of non-equilibrium molecular ensembles on the millisecond timescale

scientific article

Single-molecule transport kinetics of a glutamate transporter homolog shows static disorder

scientific article published on 29 May 2020

Site-specific labeling of the ribosome for single-molecule spectroscopy

scientific article

Small-Molecule Photostabilizing Agents are Modifiers of Lipid Bilayer Properties ⬇️

scientific article published on June 4, 2013

Solution structure of the A loop of 23S ribosomal RNA

scientific article

Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis

scientific article

Structure and Dynamics of the Mammalian Ribosomal Pretranslocation Complex

scientific article

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

scientific article

Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic

scientific article

Structures of the bacterial ribosome in classical and hybrid states of tRNA binding

scientific article

Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome

scientific article published on 21 June 2016

Subnanometer structures of HIV-1 envelope trimers on aldrithiol-2-inactivated virus particles

scientific article published on 29 June 2020

The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor

scientific article published on 19 July 2019

The bright future of single-molecule fluorescence imaging

scientific article (publication date: June 2014)

The central role of protein S12 in organizing the structure of the decoding site of the ribosome

scientific article

The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma

scientific article published on 09 November 2021

The contribution of reactive oxygen species to the photobleaching of organic fluorophores.

scientific article published on 02 December 2013

The high-energy transition state of the glutamate transporter homologue GltPh

scientific article published on 13 November 2020

The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions

scientific article published on 19 October 2017

Transport domain unlocking sets the uptake rate of an aspartate transporter.

scientific article

Transport dynamics in a glutamate transporter homologue.

scientific article published on 23 June 2013

Tuning a riboswitch response through structural extension of a pseudoknot.

scientific article

Tuning the Baird aromatic triplet-state energy of cyclooctatetraene to maximize the self-healing mechanism in organic fluorophores

scientific article published on 10 September 2020

Ultra-stable organic fluorophores for single-molecule research

scientific article

Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome

scientific article published on 01 April 2019

Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression

scientific article published on 28 February 2018

When starting over makes more sense.

scientific article published on February 2009

Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I.

scientific article

X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release

scientific article published on 21 February 2020

rRNA chemical groups required for aminoglycoside binding.

scientific article

tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis

scientific article published on 01 December 2018

tRNA selection and kinetic proofreading in translation

scientific article published on 26 September 2004

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