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List of works by Jean Martinez

"Carba" peptide bond surrogates. Different approaches to Gly-psi(CH2-CH2)-D,L-Xaa pseudo-dipeptide units

scientific article published in March 1992

(L)-(Trimethylsilyl)alanine synthesis exploiting hydroxypinanone-induced diastereoselective alkylation.

scientific article published on 26 April 2013

(R)- or (S)-4-(3-hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl)benzoic acid as a new chiral auxiliary for solid phase asymmetric Diels–Alder reactions

scholarly article by Rhalid Akkari et al published August 2004 in Tetrahedron: Asymmetry

(R)-(4-(Benzyloxycarbonylphenyl)-3-hydroxy-4,4-dimethyl-2-pyrrolidinone) acrylate derivative as a chiral dienophile for the synthesis of enantiopure 2-aminocyclohexane carboxylic acids

(S)-(3-Hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl) acetic acid as a solid supported chiral auxiliary in the asymmetric synthesis of β2-homoarylglycines

(S)-ABOC: A Rigid Bicyclic β-Amino Acid as Turn Inducer

scientific article published on 31 January 2012

1,1′-Carbonyldiimidazole and Mechanochemistry: A Shining Green Combination

1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases

scientific article

12/14/14-Helix Formation in 2:1 α/β-Hybrid Peptides Containing Bicyclo[2.2.2]octane Ring Constraints.

scientific article

1H and 13C n.m.r. studies of pseudo-peptide analogues of the C-terminal tetrapeptide of gastrin

scientific article

1H n.m.r. conformational studies on the C-terminal octapeptide of oxyntomodulin, a β-turn locked by a salt bridge

scientific article published on 01 October 1989

2,5-IMIDAZOLIDINEDIONE FORMATION FROM SEVEN MEMBERED CYCLODIPEPTIDE REARRANGEMENT

2-(Trimethylsilyl)ethanesulfonyl (or SES) Group in Amine Protection and Activation

2-(Trimethylsilyl)ethanesulfonyl (or SES) Group in Amine Protection and Activation

2-Phenylethyl ester and 2-phenylethyl amide derivative analogues of the C-terminal hepta- and octapeptide of cholecystokinin

2-Trimethylsilylethanesulfonyl (SES) versus Tosyl (Ts) Protecting Group in the Preparation of Nitrogen-Containing Five-Membered Rings. A Novel Route for the Synthesis of Substituted Pyrrolines and Pyrrolidines

A C-terminal aldehyde analog of the insect kinins inhibits diuresis in the housefly

scientific article published on 28 November 2006

A C-terminal aldehyde insect kinin analog enhances inhibition of weight gain and induces significant mortality in Helicoverpa zea larvae

scientific article

A C-terminal cyclic 8-13 neurotensin fragment analog appears less exposed to neprilysin when it crosses the blood-brain barrier than the cerebrospinal fluid-brain barrier in mice

scientific article published in October 1996

A Divergent Synthetic Strategy Based on the Regioselective Reductive Ring-Opening of a Cyclic 1,2-p-Methoxybenzylidene Acetal

A General Approach to the Aza-Diketomorpholine Scaffold

scientific article published on 17 January 2017

A Microwave-Assisted Heck Reaction in Poly(ethylene glycol) for the Synthesis of Benzazepines

article

A New Highly Versatile Handle for Chemistry on a Solid Support: The Pipecolic Linker

article by Nicolas Masurier et al published 2 August 2012 in Chemistry—A European Journal

A New Way to Silicone-Based Peptide Polymers

A Novel Route to Pseudoproline (ΨH,HPro)-Containing Dipeptides Building Blocks

A Novel Series of Growth Hormone Secretagogues

A Rational Approach to the Design and Synthesis of a New Bradykinin B1Receptor Antagonist

scientific article published on 01 June 2000

A Route to “all-cis” 2-Methyl-6-Substituted Piperidin-3-ol Alkaloids from syn-(2R,1′S)-2-(1-Dibenzylaminomethyl)epoxide: Rapid Total Synthesis of (+)-Deoxocassine

A Straightforward Approach for Cellular-Uptake Quantification

A bicyclic unit reversal to stabilize the 12/14-helix in mixed homochiral oligoureas

scientific article published on 12 June 2020

A cholecystokinin agonist/antagonist according to dose and time of action: Effect on food intake

scientific article published on 01 December 1990

A concerted mechanism for opening the GDP binding pocket and release of the nucleotide in hetero-trimeric G-proteins

scientific article published on 30 May 2011

A facile synthesis of chiral N-protected β-amino alcohols

article published in 1991

A flexible synthesis of C33-C39 polyketide region of apratoxin: Synthesis of natural and unnatural analogues

A focus on the asymmetric synthesis of a novel threo-β-benzyl-β-hydroxy aspartate analogue

A general route to “carba” peptide bond replacements: Unequivocal synthesis of Boc--Phe-ψ(CH2-CH2)--Ala-OH and Boc--Phe-ψ(CH2-CH2)--Ala-OH

article published in 1990

A heterometallic (Fe6Na8) cage-like silsesquioxane: synthesis, structure, spin glass behavior and high catalytic activity

scholarly article in RSC Advances, vol. 6 no. 53, 2016

A mechanochemical approach to access the proline-proline diketopiperazine framework

scientific article

A more sustainable and efficient access to IMes·HCl and IPr·HCl by ball-milling

A new class of arylpiperazine derivatives: the library synthesis on SynPhase lanterns and biological evaluation on serotonin 5-HT(1A) and 5-HT(2A) receptors

scientific article published in September 2004

A new class of potent gastrin antagonists

scientific article published on 01 November 1984

A new generation of cross-linkers for selective detection by MALDI MS.

scientific article

A new high-loading water-soluble scavenger for anhydrides, acid chlorides and isocyanates

A new highly versatile handle for chemistry on a solid support: the pipecolic linker

scientific article published in July 2010

A new key intermediate in the synthesis of 6-oxopiperidine-2-carboxylate derivatives

A new way to silicone-based peptide polymers

scientific article published on 4 February 2015

A side-reaction in the SPPS of Trp-containing peptides

scientific article published on 01 October 1999

A specific protein disorder catalyzer of HIV-1 Nef

article

A straightforward approach for cellular-uptake quantification

scientific article

A study on application of impregnated synthetic peptide TLC stationary phases for the screening of 5-HT1A ligands. Part 2.

scientific article

A switchable stapled peptide

scientific article published on 19 January 2016

A synthetic glycine-extended bombesin analogue interacts with the GRP/bombesin receptor

scientific article published on September 2000

A tandem aza-Friedel–Crafts reaction/Hantzsch cyclization: a simple procedure to access polysubstituted 2-amino-1,3-thiazoles

A3 -Coupling Reaction and [Ag(IPr)2 ]PF6 : A Successful Couple

ACE-like hydrolysis of gastrin analogs and CCK-8 by fundic mucosal cells of different species with release of the amidated C-terminal dipeptide

scientific article published in June 1990

Abilities of some tryptophan and phenylalanine derivatives to inhibit gastric acid secretion

scientific article published on 01 May 1985

Ac-[3- and 4-Alkylthioproline31]-CCK4 Analogs: Synthesis and Implications for the CCK-B Receptor-Bound Conformation

scientific article published on 01 January 1995

Access to α,α-Disubstituted Disilylated Amino Acids and Their Use in Solid-Phase Peptide Synthesis

scientific article published on 08 September 2015

Activated N-nitrosocarbamates for regioselective synthesis of N-nitrosoureas

scientific article published on 01 February 1982

Activated sulfahydantoin as Boc-glycine enolate equivalent: highly diastereoselective α-hydroxyalkylation and application to the synthesis of aldopentonate analogues

Activation of the ghrelin receptor is described by a privileged collective motion: a model for constitutive and agonist-induced activation of a sub-class A G-protein coupled receptor (GPCR).

scientific article published on 25 September 2009

Active esters of 9-fluorenylmethyloxycarbonyl amino acids and their application in the stepwise lengthening of a peptide chain

article published in 1980

Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling

scientific article

All-L-Leu-Pro-Leu-Pro: a challenging cyclization

scientific article published on 01 November 2000

Allongement de la cha⌝ne peptidique du côté c-terminal d'un glycosylaminoacide

scientific article published on 01 August 1976

Alternative Energy Input for Transfer Hydrogenation using Iridium NHC Based Catalysts in Glycerol as Hydrogen Donor and Solvent

scholarly article by Arturo Azua et al published 7 May 2012 in Organometallics

Alternative Technologies That Facilitate Access to Discrete Metal Complexes

scientific article published on 06 May 2019

Amino acids as building blocks for the synthesis of substituted 1,2,4-triazoles

An efficient diastereoselective synthesis of β-1-formyl-2,3,4,6-tetra-O-benzyl-d-glucopyranoside

An efficient synthesis of pyrido-imidazodiazepinediones

An innovative strategy for sulfopeptides analysis using MALDI-TOF MS reflectron positive ion mode

article

An intermediate in a new synthesis approach to beta-substituted beta-hydroxyaspartame

scientific article published on 22 July 2003

Anorexigenic and electrophysiological actions of novel ghrelin receptor (GHS-R1A) antagonists in rats

scientific article published on 5 April 2009

Anticonvulsant effect of a ghrelin receptor agonist in 6Hz corneally kindled mice

scientific article published on 5 July 2016

Application of the ring-closing metathesis to the formation of 2-aryl-1 H -pyrrole-3-carboxylates as building blocks for biologically active compounds

Are C-terminal octapeptide of cholecystokinin and [Leu11]gastrin-(5–17) different in stimulating acid secretion in isolated rabbit gastric glands?

scientific article published on 01 December 1995

Arginine 336 and asparagine 333 of the human cholecystokinin-A receptor binding site interact with the penultimate aspartic acid and the C-terminal amide of cholecystokinin.

scientific article

Arylpiperazines with N-acylated amino acids as 5-HT1A receptor ligands

scientific article published on 3 May 2006

Asymmetric Baylis–Hillman reactions using (R)-4-(3-hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl) benzoic acid acrylate derivatives in solution and on solid support

Asymmetric Diels–Alder Cycloaddition of 1-Aminocyclohexadiene to Chiral Acrylate: Synthesis of Enantiopure Bridgehead-Aminobicyclo[2.2.2]octane-2-carboxylic Acid Derivatives

Asymmetric Diels–Alder Reaction of Aminodienes with a Nonracemic Acrylate Bound to Rink Resin: A Comparison of These Reactions with Their Solution-State Analogues

article by Olivier Songis et al published January 2008 in European Journal of Organic Chemistry

Asymmetric Diels–Alder reaction using a new chiral β-nitroacrylate for enantiopure trans-β-norbornane amino acid preparation

article published in 2007

Asymmetric Synthesis of β2-Tryptophan Analogues via Friedel–Crafts Alkylation of Indoles with a Chiral Nitroacrylate

Asymmetric synthesis of (2S,3R,4R)-ethoxycarbonylcyclopropyl phosphonoglycine

Attenuation of cocaine-induced locomotor sensitization in rats sustaining genetic or pharmacologic antagonism of ghrelin receptors

scientific article published on 25 July 2011

Automated monitoring of phosphatidylcholine biosyntheses in Plasmodium falciparum by electrospray ionization mass spectrometry through stable isotope labeling experiments

scientific article

Automated versus Manual Profiling of Peptide Libraries by Mass Spectrometry

Automated vs manual profiling of peptide libraries by mass spectrometry

BACE1- and BACE2-expressing human cells: characterization of beta-amyloid precursor protein-derived catabolites, design of a novel fluorimetric assay, and identification of new in vitro inhibitors

scientific article published on 7 May 2003

Bactericidal activity of tuftsin

scientific article published on 01 December 1981

Bactericidal activity of tuftsin

Behavioral effects of the cyclic cholecystokinin peptide analogue JMV-320.

scientific article published in January 1995

Behavioural effects of two cholecystokinin analogues: JMV 236 and JMV 179.

scientific article published in September 1994

Bioactive peptides grafted silicone dressings: A simple and specific method

Biocompatible Glycine-Assisted Catalysis of the Sol-Gel Process: Development of Cell-Embedded Hydrogels

scientific article published on 24 October 2019

Biological activities of cionin and some synthetic analogs

Biological activity of silylated amino acid containing substance P analogues.

scientific article published in March 2004

Biological effects of human gastrin I and II chemically modified at the tetrapeptide amide

scientific article published on 01 May 1992

Biological evaluation of JMV180 cholecystokinin analogs

scientific article

Bioorganic hybrid OMS by straightforward grafting of trialkoxysilyl peptides

scientific article published on 10 May 2013

Biophysical characterization of a binding site for TLQP-21, a naturally occurring peptide which induces resistance to obesity

scientific article

Biosynthesis and posttranslational processing of the neurotensin/neuromedin N precursor in the rat medullary thyroid carcinoma 6-23 cell line. Effect of dexamethasone

scientific journal article

C 1 -Symmetric 1,2-Diaminobicyclo[2.2.2]octane Ligands in Copper-Catalyzed Asymmetric Henry Reaction: Catalyst Development and DFT Studies

article

C-terminal heptapeptide of gastrin inhibits astrocytomas motility by interacting with a new gastrin binding site.

scientific article

C9/12 Ribbon-Like Structures in Hybrid Peptides Alternating α- and Thiazole-Based γ-Amino Acids.

scientific article published on 9 October 2017

CCK-JMV-180: a peptide that distinguishes high-affinity cholecystokinin receptors from low-affinity cholecystokinin receptors

article

Cage-like Copper(II) Silsesquioxanes: Transmetalation Reactions and Structural, Quantum Chemical, and Catalytic Studies

scientific article published on 07 May 2015

Carboxamidomethyl esters (CAM esters) as carboxyl protecting groups

Cathepsin D displays in vitro beta-secretase-like specificity.

scientific article published on March 1997

Cell surface expression of melanocortin-1 receptor on HaCaT keratinocytes and alpha-melanocortin stimulation do not affect the formation and repair of UVB-induced DNA photoproducts

scientific article published on 16 February 2007

Changes in brain neuropeptide Y induced by cholecystokinin peptides

scientific article

Changes in hypothalamic neuropeptide Y concentrations induced by cholecystokinin analogues

scientific article

Characterization of Soluble Polymer Supported Organic Compounds by LC/Electrospray Ionization MS Toward a Complete Automation of the Liquid-Phase Process in Combinatorial Chemistry

article

Characterization of the differentiation of human colorectal cancer cell lines by means of Voronoi diagrams

scientific article published on October 1993

Characterization of the novel CCK analogs JMV-180, JMV-320, and JMV-332 in H345 cells

scientific article published on November 1992

ChemInform Abstract: A New High-Loading Water-Soluble Scavenger for Anhydrides, Acid Chlorides and Isocyanates

ChemInform Abstract: A Silaproline-Containing Dipeptide

ChemInform Abstract: A Tandem Aza-Friedel-Crafts Reaction/Hantzsch Cyclization: A Simple Procedure to Access Polysubstituted 2-Amino-1,3-thiazoles

article published in 2011

ChemInform Abstract: Amino Acids and Peptides in Ball Milling

ChemInform Abstract: An Efficient Synthesis of Pyrido-Imidazodiazepinediones

ChemInform Abstract: An Improved Synthesis of (S)- or (R)-N-Boc-Protected 1,5-Benzothiazepine Derivatives

ChemInform Abstract: Asymmetric Synthesis of (S)-β2-Homoarylglycines

ChemInform Abstract: Chemistry in Ring-Fused Oxazine-2,4-diones

ChemInform Abstract: Chiral Sulfoxides as Building Blocks for Enantiopure 1,3-Diol Precursors in the Synthesis of Natural Products

ChemInform Abstract: Combinatorial Chemistry on Solid Support in the Search for Central Nervous System Agents

ChemInform Abstract: Comprehensive Study of the Organic-Solvent-Free CDI-Mediated Acylation of Various Nucleophiles by Mechanochemistry

ChemInform Abstract: Copper-Catalyzed Direct Synthesis of Benzamides from Alcohols and Amines

ChemInform Abstract: Cross-Claisen Condensation of N-Fmoc-Amino Acids - A Short Route to Heterocyclic γ-Amino Acids

ChemInform Abstract: Efficient Chemoenzymatic Synthesis of Enantiomerically Pure β-Heterocyclic Amino Acid Derivatives

ChemInform Abstract: Electrophilic Iodo-Mediated Cyclization in PEG under Microwave Irradiation: Easy Access to Highly Functionalized Furans and Pyrroles

article by Rosella Spina et al published 7 September 2012 in ChemInform

ChemInform Abstract: From Diketopiperazines to Hydantoins: An Unprecedented Rearrangement

ChemInform Abstract: From Thienodiazepinediones to Thienopyridinones: Flexible Synthesis of Substituted Thieno[3,2-e][1,4]diazepinones and 6-Aminothieno[3,2-b]pyridinones

ChemInform Abstract: Full Stereochemical Understanding in a New (2R,3R,4R)-4-Hydroxyisoleucine Synthesis

ChemInform Abstract: Highly Selective Intermolecular Heck Reaction for the Soluble Polymer Supported Synthesis of Glutamic Acid Analogues

ChemInform Abstract: Investigation into the Enantioselective Protonation of Enolate Schiff Bases with (R)-Pantolactone

ChemInform Abstract: Iron-Catalyzed Benzamide Formation. Application to the Synthesis of Moclobemide

ChemInform Abstract: Iron/Caffeine as a Catalytic System for Microwave-Promoted Benzamide Formation

ChemInform Abstract: Mechanosynthesis of Amides in the Total Absence of Organic Solvent from Reaction to Product Recovery

ChemInform Abstract: MgI2-Mediated Chemoselective Cleavage of Protecting Groups: An Alternative to Conventional Deprotection Methodologies

ChemInform Abstract: Microwave-Assisted Neat Procedure for the Petasis Reaction

ChemInform Abstract: Multi-Gram Scale Mercury-Free Synthesis of Optically Pure 3,4,5-Trisubstituted 1,2,4-Triazoles Using Silver Benzoate

ChemInform Abstract: N-Substituted Glycines with Functional Side-Chains for Peptoid Synthesis

ChemInform Abstract: PEG3400-Cu2O-Cs2CO3: An Efficient and Recyclable Microwave-Enhanced Catalytic System for Ligand-Free Ullmann Arylation of Indole and Benzimidazole

ChemInform Abstract: Palladium N-Heterocyclic Carbene Catalysts for the Ultrasound-Promoted Suzuki-Miyaura Reaction in Glycerol

ChemInform Abstract: Poly(ethylene glycol) as Reaction Medium for Mild Mizoroki-Heck Reaction in a Ball-Mill

ChemInform Abstract: Preparation of Chiral Amino Esters by Asymmetric Phase-Transfer Catalyzed Alkylations of Schiff Bases in a Ball Mill

ChemInform Abstract: Preparation of Enantioenriched Iodinated Pyrrolinones by Iodocyclization of α-Amino-ynones

ChemInform Abstract: Regioselective Reaction of Unprotected Sugars with Urethane N-Carboxyanhydrides for the Synthesis of New Surfactants

ChemInform Abstract: Selective [3 + 2] Huisgen Cycloaddition. Synthesis of trans-Disubstituted Triazolodiazepines from Aza-Baylis-Hillman Adducts

ChemInform Abstract: Silicon-Containing Amino Acids: Synthetic Aspects, Conformational Studies, and Applications to Bioactive Peptides

ChemInform Abstract: Solvent-Free Microwave-Assisted Suzukiâ Miyaura Coupling Catalyzed by PEPPSI-iPr

ChemInform Abstract: Solvent-Free Synthesis of Hydrazones and Their Subsequent N-Alkylation in a Ball-Mill

ChemInform Abstract: Solvent-Free Synthesis of Nitrones in a Ball-Mill

ChemInform Abstract: Solvent-Free Synthesis of Unsaturated Amino Esters in a Ball-Mill

ChemInform Abstract: Solventless Mechanosynthesis of N-Protected Amino Esters

ChemInform Abstract: Stereoselective Synthesis of Original Spirolactams Displaying Promising Folded Structures

ChemInform Abstract: Straightforward Synthesis of Chiral Silylated Amino Acids Through Hydrosilylation

ChemInform Abstract: Synthesis of (S)-N-Boc-3-amino-2-arylpropanol from Optically Active β-Amino Esters

ChemInform Abstract: Synthesis of Cyclic Amino Acid Derivatives via Ring Closing Metathesis on a Poly(ethylene glycol)-Supported Substrate

ChemInform Abstract: Synthesis of Novel Pyrrolo-[3,2-c]quinolines via Iron-Catalyzed Cross-Coupling Reaction of Grignard Reagents

ChemInform Abstract: Synthesis of Silaproline, a New Proline Surrogate

ChemInform Abstract: Synthesis of Thieno[3,2-e][1,4]diazepin-2-ones: Application of an Uncatalyzed Pictet-Spengler Reaction

ChemInform Abstract: Synthesis of Various Chiral 1,2,4-Triazole-Containing α-Amino Acids from Aspartic or Glutamic Acids

article published in 2011

ChemInform Abstract: Synthesis of a New Hydrophilic Poly(ethylene glycol)-ionic Liquid and Its Application in Peptide Synthesis

ChemInform Abstract: The Negishi Cross-Coupling in the Synthesis of Natural Products and Bioactive Molecules

ChemInform Abstract: Transannular Rearrangement of Activated Lactams: Stereoselective Synthesis of Substituted Pyrrolidine-2,4-diones from Diketopiperazines

ChemInform Abstract: Ultrasounds in Melted Poly(ethylene Glycol) Promote Copper-Catalyzed Cyanation of Aryl Halides with K4[Fe(CN)6]

ChemInform Abstract: aza-Baylis-Hillman Reaction

Chemical cross-linkers for protein structure studies by mass spectrometry

scientific article

Chemical insights into bioinks for 3D printing

scientific article published on 01 July 2019

Chemical optimization of new ligands of the low-density lipoprotein receptor as potential vectors for central nervous system targeting.

scientific article published on 14 February 2012

Chemistry of Ring-Fused Oxazine-2,4-diones

Chemo-enzymatic synthesis of new non ionic surfactants from unprotected carbohydrates

scientific article

Chemoenzymatic Synthesis of Enantiomerically Pure (2S,3R,4S)-4-Hydroxyisoleucine, an Insulinotropic Amino Acid Isolated from Fenugreek Seeds

Chemoenzymatic routes to enantiomerically pure 2-azatyrosine and 2-, 3- and 4-pyridylalanine derivatives

Chemoenzymatic synthesis of surfactants from carbohydrates, amino acids, and fatty acids

scientific article published in February 2001

Chemoenzymatic synthesis of the two enantiomers of 7-azatryptophan

scholarly article by L Lecointe et al published May 1998 in Tetrahedron: Asymmetry

Chemoselective cross-linking of alginate with thiol-terminated peptides for tissue engineering applications

scholarly article by Silvia Bubenikova et al published May 2012 in Carbohydrate Polymers

Chiral Sulfoxides as Building Blocks for Enantiopure 1,3-Diol Precursors in the Synthesis of Natural Products

Chiral synthetic pseudopeptidic derivatives as triplet excited state quenchers

Cholecystokinin (CCK)-induced desensitization of pancreatic enzyme secretion is mediated by low affinity CCK receptors

scientific article published in March 1989

Cholecystokinin (pancreozymin). 4. Synthesis and properties of a biologically active analog of the C-terminal heptapeptide with .epsilon.-hydroxynorleucine sulfate replacing tyrosine sulfate

scientific article published on 01 October 1978

Cholecystokinin (pancreozymin). 5. Hormonally active desamino derivative of Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2.

scientific article

Cholecystokinin 1 receptor modulates the MEKK1-induced c-Jun trans-activation: structural requirements of the receptor

scientific article published on April 2006

Cholecystokinin and gastrin are not equally sensitive to GTP gamma S at CCKB receptors: importance of the sulphated tyrosine.

scientific article published on July 1995

Cholecystokinin increases intracellular Ca2+ concentration in the Human JURKAT T Lymphocyte cell line

scientific article published on May 1993

Cholecystokinin receptors in cells of the immune system

scientific article published on March 1994

Cholecystokinin suppresses food intake in cats: Structure-activity characterization

scientific article published on 01 October 1988

Clinical use of p-proteasome in discriminating metastatic melanoma patients: Comparative study with LDH, MIA and S100B protein

Coarse-Grained Prediction of Peptide Binding to G-Protein Coupled Receptors.

scientific article published on 23 February 2017

Coarse-grained simulations of the HIV-1 matrix protein anchoring: revisiting its assembly on membrane domains

scientific article published on February 2014

Combinatorial chemistry on solid support in the search for central nervous system agents

scientific article

Combining sol-gel and microfluidics processes for the synthesis of protein-containing hybrid microgels

scientific article published on 01 October 2019

Comparative Study of In Vitro and In Vivo Activities of Bombesin Pseudopeptide Analogs Modified on the C-Terminal Dipeptide Fragment

scientific article published on 01 January 1998

Comparative activity of two cholecystokinin analogues with partial agonist activity: effects on food intake and brain monoamines

scientific article published in September 1990

Comparative study of oxyntomodulin and its C-terminal octapeptide on the gastric acid secretion in rat

Comparison of LID versus CID activation modes in tandem mass spectrometry of peptides

scientific article

Comparison of inert supports in laser desorption/ionization mass spectrometry of peptides: pencil lead, porous silica gel, DIOS-chip and NALDI target

scientific article

Comprehensive study of the organic-solvent-free CDI-mediated acylation of various nucleophiles by mechanochemistry

scientific article published on 14 July 2015

Comprehensive study on olefin metathesis in PEG as an alternative solvent under microwave irradiation

Concise Pathway to New Multifunctionalized Constrained Pentacin Derivatives by Means of Two Stereospecific Tandem Reactions

article by Thibault Coursindel et al published 15 July 2011 in European Journal of Organic Chemistry

Conformational Equilibrium of CDK/Cyclin Complexes by Molecular Dynamics with Excited Normal Modes

scientific article

Conformational restriction of G-proteins Coupled Receptors (GPCRs) upon complexation to G-proteins: a putative activation mode of GPCRs?

scientific article published on 10 July 2013

Conformational studies of proline-, thiaproline- and dimethylsilaproline-containing diketopiperazines

scholarly article by Florine Cavelier published in January 2006

Conformationally Constrained Peptidomimetics as Inhibitors of the Protein Arginine Methyl Transferases.

scientific article

Conformationally readdressed CCK-B/delta-opioid peptide ligands

scientific article

Constitutive expression of MC1R in HaCaT keratinocytes inhibits basal and UVB-induced TNF-alpha production.

scientific article

Continuous flow ring-closing metathesis, an environmentally-friendly route to 2,5-dihydro-1H-pyrrole-3-carboxylates

article published in 2017

Contribution of the proteasome to the alpha-secretase pathway in Alzheimer's disease

scientific article published on January 1997

Convenient Two-Step Preparation of [1,2,4]Triazolo[4,3-a]pyridines from 2-Hydrazinopyridine and Carboxylic Acids

Convenient two-step preparation of [1,2,4]triazolo[4,3-a]pyridines from 2-hydrazinopyridine and carboxylic acids

article by Aline Moulin et al published October 2006 in Tetrahedron Letters

Copper-Catalyzed Direct Synthesis of Benzamides from Alcohols and Amines

scholarly article by Xavier Bantreil et al published 20 September 2012 in ChemCatChem

Copper-Containing Rod-Shaped Nanosized Silica Particles for Microwave-Assisted Synthesis of Triazoles in Aqueous Solution

Correction to Mechanochemical Preparation of 3,5-Disubstituted Hydantoins from Dipeptides and Unsymmetrical Ureas of Amino Acid Derivatives

scientific article published on 15 November 2016

Correction: A heterometallic (Fe6Na8) cage-like silsesquioxane: synthesis, structure, spin glass behavior and high catalytic activity

scholarly article in RSC Advances, vol. 6 no. 57, 2016

Correlation between phospholipid breakdown, intracellular calcium mobulization and enzyme secretion in rat pancreatic acini treated with Boc-[Nle28, Nle31]-CCK-7 and JMV180, two cholecystokinin analogues

scientific article published on 01 January 1990

Cross-Claisen Condensation ofN-Fmoc-Amino Acids - A Short Route to Heterocyclic γ-Amino Acids

Cross-interactions of two p38 mitogen-activated protein (MAP) kinase inhibitors and two cholecystokinin (CCK) receptor antagonists with the CCK1 receptor and p38 MAP kinase

scientific article

Cu(0), O2 and mechanical forces: a saving combination for efficient production of Cu-NHC complexes.

scientific article published on 28 September 2016

Cyclic Peptides with a Diversely Substituted Guanidine Bridge: Solid-Phase Synthesis and Structural Analysis

article

Cyclic RGD peptide by ring-closing metathesis

Cyclic enkephalins with a diversely substituted guanidine bridge or a thiourea bridge: synthesis, biological and structural evaluations

scientific article published on 12 July 2013

Cyclization of peptides through a urea bond: application to the Arg-Gly-Asp tripeptide

scientific article

Cyclosulfamide as a chiral auxiliary: application to efficient asymmetric synthesis (alkylation/aldolization)

Cystatin C secretion by rat glomerular mesangial cells: autocrine loop for in vitro growth-promoting activity

scientific journal article

Cytotoxic activity of new racemic and optically active N-phosphonoalkyl bicyclic β-amino acids against human malignant cell lines

scientific article published on 12 January 2012

Decreased expression of thymidine phosphorylase/platelet-derived endothelial cell growth factor in basal cell carcinomas

scientific article

Decreased human epidermal antigen-presenting cell activity after ultraviolet A exposure: dose–response effects and protection by sunscreens

article

Degradation of cholecystokinin octapeptide by the neutral endopeptidase EC 3.4.24.11 and design of proteolysis-resistant analogues of the peptide

scientific article published on 01 January 1987

Dehydroxylation reaction induced by the matrix in the fast atom bombardment mass spectra of a peptide

scholarly article by J.-L. Aubagnac et al published May 1992 in Journal of Mass Spectrometry

Deprotective activity of nanosized globular partially quaternized poly(tertiary amine)s in peptide synthesis

Design and characterization of a new cell-permeant inhibitor of the beta-secretase BACE1.

scientific article

Design and characterization of a novel cellular prion-derived quenched fluorimetric substrate of alpha-secretase

scientific article published on 21 June 2006

Design and synthesis of potent bradykinin agonists containing a benzothiazepine moiety

scientific article

Design, synthesis, and biological evaluation of 1,5-benzothiazepine-4-one derivatives targeting factor VIIa/tissue factor

scientific article published on 19 January 2009

Detergent-free Isolation of Functional G Protein-Coupled Receptors into Nanometric Lipid Particles

scientific article published on 24 December 2015

Development of an oxyntomodulin/glicentin C-terminal radioimmunoassay using a "thiol-maleoyl" coupling method for preparing the immunogen

scientific article published in August 1988

Diagnostic value and prognostic significance of plasmatic proteasome level in patients with melanoma.

scientific article published on 12 August 2010

Diastereoselective Synthesis of N-Protected β-Amino-α-hydroxyacids (Norstatines) from Urethane N-Carboxyanhydrides (UNCAs)

Diastereoselective esterification of (±)-N-trifluoroacetyl pipecolic acid using (S)-α-methyl pantolactone: synthesis of (S)-N-Boc pipecolic acid and (S)-N-Boc-2-piperidinemethanol

Diastereoselective radical addition to dehydroalanine derivatives of pantolactone

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Diastereoselective synthesis of glycosyl-α-aminoacids

Diastereospecific synthesis of new 4-substituted l-theanine derivatives

scholarly article by Fatiha Sebih et al published April 2014 in Tetrahedron: Asymmetry

Different highly selective gastrin-releasing peptide receptor (GRPR) peptide antagonists interact with different receptor domains

Dimethyl 3-benzyl-2-(4-methyl-2,5-dioxoimidazolidin-1-yl)butanedioate

scientific article

Dipeptide mimic oligomer transporter mediates intracellular delivery of Cathepsin D inhibitors: a potential target for cancer therapy

scientific article published on 27 July 2013

Direct Access to L-Azetidine-2-carboxylic Acid

Directeurs salariés de laboratoires d’analyses médicales : attention à la requalification !

Discrimination and selective enhancement of signals in the MALDI mass spectrum of a protein by combining a matrix-based label for lysine residues with a neutral matrix

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Dissociation of membrane-anchored heterotrimeric G-protein induced by G(α) subunit binding to GTP.

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Dynamic kinetic resolution of racemic N-phthalyl amino acids using (S)-α-methylpantolactone as the chiral auxiliary

scholarly article by Monique Calmes et al published February 2000 in Tetrahedron: Asymmetry

Dystrophin and utrophin complexed with different associated proteins in cardiac Purkinje fibres

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EP1572: a novel peptido-mimetic GH secretagogue with potent and selective GH-releasing activity in man.

scientific article published in September 2002

ESI mass spectrometry of amino acid trimethylsilylethyl esters.

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Early-Blind Subjects' Spatial Representation of Manipulatory Space: Exploratory Strategies and Reaction to Change

scientific article (publication date: March 1997)

Easy Synthesis of Tunable Hybrid Bioactive Hydrogels

article by Cécile Echalier et al published 16 February 2016 in Chemistry of Materials

Easy saponification by metal silanolates: application in SPPS and in (S)-5-hydroxynorvaline preparation

article by Ewelina Minta et al published March 2005 in Tetrahedron Letters

Easy synthesis and ring-opening polymerization of 5-Z-amino-δ-valerolactone: New degradable amino-functionalized (Co)polyesters

article by Sebastien Blanquer et al published 3 November 2010 in Journal of Polymer Science Part A

Effect of glicentin, oxyntomodulin and related peptides on isolated gastric smooth muscle cells

article published in 1997

Effects of a new cholecystokinin analogue (JMV 236) on food intake and brain monoamines in the rat.

scientific article published in January 1990

Effects of thiorphan, bestatin and a novel metallopeptidase inhibitor JMV 390-1 on the recovery of neurotensin and neuromedin N released from mouse hypothalamus

scientific article published in August 1992

Efficient One-Pot Microwave-Assisted Synthesis of 3-(Thien-3-yl)imidazolidine-2,4-dione Analogues

Efficient Synthesis of Nicotianamine and Non-Natural Analogues

Efficient chemoenzymatic synthesis of enantiomerically pure β-heterocyclic amino acid derivatives

Efficient one-pot microwave-assisted synthesis of 3-(thien-3-yl)imidazolidine-2,4-dione analogs

Efficient solid-phase synthesis of 4,5-dihydro-1,2,4-triazin-6(1H)-ones

Efficient synthesis of functionalized α-aryl α-aminoesters via reaction of polyfunctional diarylzincs with a glycine cation equivalent

Efficient synthetic approach to heterocycles possessing the 3,3-disubstituted-2,3-dihydrobenzofuran skeleton via diverse palladium-catalyzed tandem reactions

Electrophilic Iodo-Mediated Cyclization in PEG under Microwave Irradiation: Easy Access to Highly Functionalized Furans and Pyrroles

article by Frédéric Lamaty et al published 25 May 2012 in Synlett

Electrospray mass spectrometry of 2-aminotroponimines and 2-aminotropones

scientific article published in January 2003

Enantiodivergent Transannular Rearrangement of 3-Isopropyl-1,4-benzodiazepine-2,5-dione by Memory of Chirality

Enantioselective Synthesis of N-Protected α-Amino Acid Hydrazides

Enantioselective synthesis of new 4-substituted glutamic acid derivatives

article published in 2004

Engineered Adhesion Peptides for Improved Silicon Adsorption

scientific article published on 6 October 2015

Enhancing the Antimicrobial Activity of Alamethicin F50/5 by Incorporating N-terminal Hydrophobic Triazole Substituents.

scientific article published on 18 September 2017

Environmentally benign peptide synthesis using liquid-assisted ball-milling: application to the synthesis of Leu-enkephalin

Epimerization-Free C-Term Activation of Peptide Fragments by Ball Milling

scientific article published on 04 January 2021

Evidence for a direct interaction between the penultimate aspartic acid of cholecystokinin and histidine 207, located in the second extracellular loop of the cholecystokinin B receptor

scientific article (publication date: 13 August 1999)

Evidence for a role of NTS2 receptors in the modulation of tonic pain sensitivity

scientific article published on 06 July 2009

Evidence for dopaminomimetic effect of intrastriatally injected cholecystokinin octapeptide in mice

scientific article published in March 1986

Expedient Mechanosynthesis of N,N-Dialkyl Imidazoliums and Silver(I)-Carbene Complexes in a Ball-Mill

scientific article published on 22 October 2015

Expedient Synthesis of Fmoc-(S)-γ-Fluoroleucine and Late-Stage Fluorination of Peptides

External pancreatic secretion in the rat: Supramaximal inhibition induced by the cholecystokinin octapeptide [CCK(26–33)] and analogs altered on the 28–29 bond

scientific article published on 01 September 1989

FT-IR and NMR structural markers for thiazole-based γ-peptide foldamers.

scientific article published in September 2016

Facile synthesis of tert-butyl ester of N-protected amino acids with tert-butyl bromide

Faster and cleaner dynamic kinetic resolution via mechanochemistry

First asymmetric synthesis of (R)-(−)-α-phenyl δ-amino valeric acid

scholarly article by Monique Calmes et al published April 2000 in Tetrahedron: Asymmetry

Fluorescence and mass spectrometry studies of the interaction between naproxen and synthetic pseudopeptidic models in organic media

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Formation of multiple complexes between beta-dystroglycan and dystrophin family products

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Fragment-based identification of a locus in the Sec7 domain of Arno for the design of protein-protein interaction inhibitors

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From Diketopiperazines to Hydantoins: An Unprecedented Rearrangement

From Thienodiazepinediones to Thienopyridinones: Flexible Synthesis of Substituted Thieno[3,2-e][1,4]diazepinones and 6-Aminothieno[3,2-b]pyridinones

From beta-N-tert-butyloxycarbonyl N-carboxyanhydrides to beta-aminoacid derivatives

scientific article published in December 2003

From polyesters to polyamides via O-N acyl migration: an original multi-transfer reaction

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From protected trialkoxysilyl-peptide building blocks to bioorganic–silica hybrid materials

scientific article published on 31 October 2013

Full stereochemical understanding in a new (2R,3R,4R)-4-hydroxyisoleucine synthesis

scientific article published on 6 December 2001

Functionalised mesoporous silica: a good opportunity for controlled peptide oligomerisation

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Fundamentals of Modern Peptide Synthesis

Fundamentals of modern peptide synthesis

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Further characterization of a putative serine protease contributing to the γ-secretase cleavage of β-amyloid precursor protein

scholarly article by Marine Peuchmaur published in February 2013

Fused Bis-lactams to Spirolactams: A New Member in the Family of Ring-Contraction Reaction

GDP release preferentially occurs on the phosphate side in heterotrimeric G-proteins

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GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation.

scientific article published on 9 April 2018

Gastrin induces over-expression of genes involved in human U373 glioblastoma cell migration

scientific article published in October 2001

Gastrin releasing peptide receptor-directed radioligands based on a bombesin antagonist: synthesis, (111)in-labeling, and preclinical profile

scientific article published on 8 March 2013

Gastrin13 and the C-terminal octapeptide of cholecystokinin are differently coupled to G-proteins in guinea-pig brain membranes

scientific article published on May 1994

Gastrin13 binds to CCKB brain membrane receptors coupled to G protein in guinea pig brain membranes.

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General approaches to carba peptide bond surrogates

Ghrelin Receptor Ligands: Design and Synthesis of Pseudopeptides and Peptidomimetics

Ghrelin agonists impact on Fos protein expression in brain areas related to food intake regulation in male C57BL/6 mice

scientific article published on 6 August 2011

Ghrelin knockout mice show decreased voluntary alcohol consumption and reduced ethanol-induced conditioned place preference

scientific article published on 18 February 2013

Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex

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Ghrelin stimulation of growth hormone-releasing hormone neurons is direct in the arcuate nucleus

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Glicentin and oxyntomodulin modulate both the phosphoinositide and cyclic adenosine monophosphate signaling pathways in gastric myocytes

scientific article published on 01 January 1999

Glutamate transporter blockers: enantiomerically pure (2S,3S)- and (2S,3R)-3-methyl glutamic acids

Glutamic acid as a new linker for attachment of alcohols to solid support

Growth hormone secretagogues hexarelin and JMV2894 protect skeletal muscle from mitochondrial damages in a rat model of cisplatin-induced cachexia

scientific article published on 12 October 2017

Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia.

scientific article published on 10 March 2017

Growth hormone secretagogues: past, present and future.

scientific article published on August 2002

H-Lys-Arg-Asn-Lys-Asn-Asn-OH is the minimal active structure of oxyntomodulin

scientific article published on 01 January 1996

Heating and microwave assisted SPPS of C-terminal acid peptides on trityl resin: the truth behind the yield

scientific article published on 19 October 2013

Helical Oligomers of Thiazole-Based γ-Amino Acids: Synthesis and Structural Studies

scientific article published on 25 April 2013

Heterodimerization with Its splice variant blocks the ghrelin receptor 1a in a non-signaling conformation: a study with a purified heterodimer assembled into lipid discs

scientific article published on 09 July 2013

Heteromultivalent targeting of integrin αvβ3 and neuropilin 1 promotes cell survival via the activation of the IGF-1/insulin receptors.

scientific article published on 29 October 2017

High Catalytic Activity of Heterometallic (Fe6Na7 and Fe6Na6) Cage Silsesquioxanes in Oxidations with Peroxides

High constitutive activity is an intrinsic feature of ghrelin receptor protein: a study with a functional monomeric GHS-R1a receptor reconstituted in lipid discs

scientific article published on 23 November 2011

Highly Enantioselective Access to α-Dibenzylamino Ketones from Chiral Nonracemic α-Bromo α′-Sulfinyl Ketones by Dynamic Kinetic Resolution: Synthesis of (2R,1′S)-2-[1-(Dibenzylamino)alkyl]oxiranes

article published in 2011

Highly resolutive separations of hardly soluble synthetic polypeptides by capillary electrophoresis

scientific article published in January 2010

Highly selective intermolecular Heck reaction for the soluble polymer supported synthesis of glutamic acid analogues

Homogeneous time-resolved fluorescence-based assay to screen for ligands targeting the growth hormone secretagogue receptor type 1a.

scientific article published on 24 September 2010

How are 1,2,3-triazoles accommodated in helical secondary structures?

scientific article published on 25 April 2018

How ligands and signalling proteins affect G-protein-coupled receptors' conformational landscape

scientific article published on February 2013

Hydrophobic α,α-Disubstituted Disilylated TESDpg Induces Incipient 310-Helix in Short Tripeptide Sequence.

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Identification of key residues for interaction of vasoactive intestinal peptide with human VPAC1 and VPAC2 receptors and development of a highly selective VPAC1 receptor agonist. Alanine scanning and molecular modeling of the peptide

scientific article (publication date: 4 August 2000)

Identification of two amino acids of the human cholecystokinin-A receptor that interact with the N-terminal moiety of cholecystokinin.

scientific article

Identification of tyrosine 189 and asparagine 358 of the cholecystokinin 2 receptor in direct interaction with the crucial C-terminal amide of cholecystokinin by molecular modeling, site-directed mutagenesis, and structure/affinity studies

scientific article (publication date: May 2003)

Imaging combinatorial libraries by mass spectrometry: from peptide to organic-supported syntheses

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Imaging heterogeneity of peptide delivery and binding in solid tumors using SPECT imaging and MRI

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Imaging time-of-flight secondary ion mass spectrometry of solid-phase peptide syntheses

scientific article published on 01 July 1999

Imidazopyridine-fused [1,3]-diazepinones part 2: Structure-activity relationships and antiproliferative activity against melanoma cells.

scientific article published on 11 November 2016

Imidazopyridine-fused [1,3]-diazepinones: synthesis and antiproliferative activity.

scientific article published on 30 January 2014

Immunopharmacological properties of tuftsin and of some analogues

scientific article published on January 1983

Importance of the leucine side-chain to the spasmogenic activity and binding of Substance P analogues

scientific article published on 01 September 1993

Improved solid phase synthesis of C-terminal peptide aldehydes

Impurity Detection in Solid-Phase Organic Chemistry: Scope and Limits of HR MAS NMR

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In Vivo Stabilization of a Gastrin-Releasing Peptide Receptor Antagonist Enhances PET Imaging and Radionuclide Therapy of Prostate Cancer in Preclinical Studies

scientific article published on January 2016

In vitro and in vivo application of radiolabeled gastrin-releasing peptide receptor ligands in breast cancer

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In vitro influence of gastrin, oestradiol and gonadotropin-releasing hormone on HCT-15 and LoVo human colorectal neoplastic cell proliferation

scientific article published on January 1991

In vivo activities of peptide and pseudo-peptide analogs of the C-terminal octapeptide of cholecystokinin on pancreatic secretion in the rat.

scientific article published in November 1987

Indoloazepinone-Constrained Oligomers as Cell-Penetrating and Blood-Brain Barrier Permeable Compounds.

scientific article published on 29 January 2018

Influence of gastrin on human astrocytic tumor cell proliferation.

scientific article published in May 1996

Influence of silaproline on peptide conformation and bioactivity

scientific article published in March 2002

Inhibitory Effect of the C-Terminal Octapeptide of Oxyntomodulin on Pentagastrin-Stimulated Gastric Acid Secretion in Man

scientific article published on 01 December 1989

Inorganic polymerization: an attractive route to biocompatible hybrid hydrogels

scientific article published on 30 April 2018

Investigation into the enantioselective protonation of enolate Schiff bases with (R)-pantolactone

Investigation of Elemental Mass Spectrometry in Pharmacology for Peptide Quantitation at Femtomolar Levels

scientific article

Investigation of silicon-based nanostructure morphology and chemical termination on laser desorption ionization mass spectrometry performance

scientific article

Involvement of PKA and ERK pathways in ghrelin-induced long-lasting potentiation of excitatory synaptic transmission in the CA1 area of rat hippocampus

scientific article published on 8 July 2015

Involvement of PPARγ in the Anticonvulsant Activity of EP-80317, a Ghrelin Receptor Antagonist

scientific article published on 22 September 2017

Involvement of tryptophan W276 and of two surrounding amino acid residues in the high constitutive activity of the ghrelin receptor GHS-R1a

scientific article published on 30 June 2010

Ionic Complexes of Tetra- and Nonanuclear Cage Copper(II) Phenylsilsesquioxanes: Synthesis and High Activity in Oxidative Catalysis

Iron-catalyzed benzamide formation. Application to the synthesis of moclobemide

Iron/Caffeine as a Catalytic System for Microwave-Promoted Benzamide Formation

article published in 2014

Is the vasoactive intestinal peptide (VIP) a prohormone?

Is there a relationship between angiotensin converting enzyme and the mechanism of action of gastrin?

Isoxazolidine: A Privileged Scaffold for Organic and Medicinal Chemistry

scientific article published on 16 December 2016

JLK inhibitors: isocoumarin compounds as putative probes to selectively target the gamma-secretase pathway

scientific article

JLK isocoumarin inhibitors: selective gamma-secretase inhibitors that do not interfere with notch pathway in vitro or in vivo

scientific article published on November 2003

JMV 449: a pseudopeptide analogue of neurotensin-(8-13) with highly potent and long-lasting hypothermic and analgesic effects in the mouse

scientific article published in August 1992

JMV2894, a novel growth hormone secretagogue, accelerates body mass recovery in an experimental model of cachexia.

scientific article published on 28 November 2016

JMV5656, A Novel Derivative of TLQP-21, Triggers the Activation of a Calcium-Dependent Potassium Outward Current in Microglial Cells

scientific article published on 23 February 2017

JMV641: a potent bombesin receptor antagonist that inhibits Swiss 3T3 cell proliferation

scientific article published on August 1996

Joseph Rudinger memorial lecture: Unexpected functions of angiotensin converting enzyme, beyond its enzymatic activity

scientific article

Kinetics, inhibition and oligomerization of Epstein-Barr virus protease

scientific article published on 14 November 2006

L-365,260 inhibits in vitro acid secretion by interacting with a PKA pathway.

scientific article published in May 1999

L-arginine binding to human inducible nitric oxide synthase: an antisymmetric funnel route toward isoform-specific inhibitors?

scientific article

Large and prolonged in vivo response of pancreatic secretion to phenylethylamide and phenylethylester derivatives of Boc-[Nle28-Nle31]CCK(26-33) in the rat.

scientific article published in November 1992

Laser desorption ionization mass spectrometry of peptides on a hybrid CHCA organic-inorganic matrix

scientific article

Laser desorption ionization mass spectrometry of protein tryptic digests on nanostructured silicon plates

scientific article

Laser desorption/ionization mass spectrometry on porous silica and alumina for peptide mass fingerprinting

scientific article

Le chloroformiate d'isopropenyle (ipcf) en chimie des amino-acides et des peptides - iii synthese d'esters actifs d' amino acides n-proteges

Lewis Acid Induced Switch of Torquoselectivity in the Nazarov Cyclization of Activated Dienones Bearing a Chiral Sulfoxide

scientific article published on 12 September 2016

Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor

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Low energy peptide fragmentations in an ESI-Q-Tof type mass spectrometer

scientific article published on 21 February 2007

MALDI-TOF MS analysis of soluble PEG based multi-step synthetic reaction mixtures with automated detection of reaction failure

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MC1R expression in HaCaT keratinocytes inhibits UVA-induced ROS production via NADPH oxidase- and cAMP-dependent mechanisms

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MSX-3D: a tool to validate 3D protein models using mass spectrometry.

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Mass Spectrometry and Soluble Polymeric Support

Mass spectrometry and combinatorial chemistry: new approaches for direct support-bound compound identification

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Mechanochemical 1,1′-Carbonyldiimidazole-Mediated Synthesis of Carbamates

Mechanochemical Preparation of 3,5-Disubstituted Hydantoins from Dipeptides and Unsymmetrical Ureas of Amino Acid Derivatives

scientific article published on 10 October 2016

Mechanochemical preparation of hydantoins from amino esters: application to the synthesis of the antiepileptic drug phenytoin

scientific article published on 17 October 2014

Mechanochemistry for facilitated access to N,N-diaryl NHC metal complexes

Mechanosynthesis of amides in the total absence of organic solvent from reaction to product recovery

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Melanin-concentrating hormone binding sites in human SVK14 keratinocytes

scientific article

Metabolic clearance rates of oxyntomodulin and glucagon in the rat: contribution of the kidney

scientific article published in October 1990

Methods and Protocols of Modern Solid-Phase Peptide Synthesis

Methods and protocols of modern solid phase Peptide synthesis

scientific article published on July 2006

MgI2 -chemoselective cleavage for removal of amino acid protecting groups: A fresh vision for peptide synthesis

scientific article published on 8 July 2016

MgI2 -mediated chemoselective cleavage of protecting groups: an alternative to conventional deprotection methodologies

scientific article

Micelles into Glycerol Solvent: Overcoming Side Reactions of Glycerol

Microgels of silylated HPMC as a multimodal system for drug co-encapsulation

scientific article

Microwave-Assisted Copper-Catalyzed Heck Reaction in PEG Solvent

Microwave-Assisted Copper-Catalyzed Heck Reaction in PEG Solvent

Microwave-Assisted Copper-Catalyzed Sonogashira Reaction in PEG Solvent

Microwave-Assisted Copper-Catalyzed Sonogashira Reaction in PEG Solvent

Microwave-Assisted Hydantoins Synthesis on Solid Support

Microwave-Assisted Neat Procedure for the Petasis Reaction

Microwave-assisted Solid Phase Peptide Synthesis on High Loaded Resins

Microwave-assisted Stereoselective Synthesis

Microwave-assisted aza-Baylis-Hillman Reaction. Preparation of Poly(ethylene Glycol) Supported α-methylene-β-Aminoester

Microwave-assisted multi-step synthesis of novel pyrrolo-[3,2-c]quinoline derivatives

article by Hafid Benakki et al published June 2008 in Tetrahedron

Microwave-assisted solid-phase synthesis of hydantoin derivatives

Microwave-mediated reduction of disulfide bridges with supported (tris(2-carboxyethyl)phosphine) as resin-bound reducing agent

scientific article published on 8 March 2013

Microwave-ultrasound simultaneous irradiation: a hybrid technology applied to ring closing metathesis

scholarly article in RSC Advances, vol. 5 no. 22, 2015

Mixed oligoureas based on constrained bicyclic and acyclic β-amino acids derivatives: on the significance of the subunit configuration for folding.

scientific article

Modification of receptor selectivity and functional activity of cyclic cholecystokinin analogues

article published in 1998

Modular bioink for 3D printing of biocompatible hydrogels: sol–gel polymerization of hybrid peptides and polymers

scholarly article in RSC Advances, vol. 7 no. 20, 2017

Modulation of phagocytosis-associated respiratory burst by human cystatin C: role of the N-terminal tetrapeptide Lys-Pro-Pro-Arg

scientific article published on May 1990

Molecular basis for selectivity of high affinity peptide antagonists for the gastrin-releasing peptide receptor

scientific journal article

Molecular mechanism underlying partial and full agonism mediated by the human cholecystokinin-1 receptor

scientific article published on 4 January 2005

Molecular modeling study for a novel structured oligomer subunit selection: the example of 2-aminomethyl-phenyl-acetic acid

Monitoring and quantification on solid support of a by-product formation during peptide synthesis by Tof-SIMS

Multi-gram scale mercury-free synthesis of optically pure 3,4,5-trisubstituted 1,2,4-triazoles using silver benzoate

N- and O-acetylation of threonine residues in the context of proteomics

N-Acyl Benzotriazole Derivatives for the Synthesis of Dipeptides and Tripeptides and Peptide Biotinylation by Mechanochemistry

N-Pyrrolidine-based α/β-peptides incorporating ABOC, a constrained bicyclic β-amino acid, for asymmetric aldol reaction catalysis

article by Pierre Milbeo et al published March 2016 in Tetrahedron

N-Substituted Glycines with Functional Side-Chains for Peptoid Synthesis

N-acetyl oxyntomodulin30?37: pharmacokinetics and activity on gastric acid secretion

scientific article published on 01 January 1992

N-benzhydryl-glycolamide esters (OBg esters) as carboxyl protecting groups in pept1de synthesis

article published in 1988

N-terminus FITC labeling of peptides on solid support: the truth behind the spacer

Neuroblastoma differentiation involves the expression of two isoforms of the alpha-subunit of Go.

scientific article published in April 1990

Neurotensin Receptor Down-Regulation Induced by Dexamethasone and Forskolin in Rat Hypothalamic Cultures is Mediated by Endogenous Neurotensin

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Neurotensin and its high affinity receptor 1 as a potential pharmacological target in cancer therapy

scientific article published on January 2012

Neurotensin modulates the electrical activity of frog pituitary melanotropes via activation of a G-protein-coupled receptor pharmacologically related to both the NTS1 and nts2 receptors of mammals.

scientific article

Neurotensin-mediated effects on astrocytic tumor cell proliferation

scientific article published in April 1996

Neutrophil chemotactic activity is modulated by human cystatin C, an inhibitor of cysteine proteases

scientific article published in June 1990

New 1,3-amino alcohols derived from enantiopure bridgehead β-aminobicyclo[2.2.2]oct-5-ene-2-carboxylic acids

New Soluble-Polymer Bound Ruthenium Carbene Catalysts: Synthesis, Characterization, and Application to Ring-Closing Metathesis

New Soluble-Polymer Bound Ruthenium Carbene Catalysts: Synthesis, Characterization, and Application to Ring-Closing Metathesis

scholarly article by Stéphane Varray et al published June 2003 in Organometallics

New Synthetic and Natural Tuftsin-related Compounds and Evaluation of Their Phagocytosis-stimulating Activity

scientific article published on 01 January 1983

New active series of growth hormone secretagogues

scientific article published on March 2003

New example of proline-induced fragmentation in electrospray ionization mass spectrometry of peptides

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New general strategy of dimerization of bioactive molecules

New ligands of the ghrelin receptor based on the 1,2,4-triazole scaffold by introduction of a second chiral center

scholarly article by Mathieu Maingot published in May 2016

New trisubstituted 1,2,4-triazole derivatives as potent ghrelin receptor antagonists. 3. Synthesis and pharmacological in vitro and in vivo evaluations

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New trisubstituted 1,2,4-triazoles as ghrelin receptor antagonists

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NewC-Glycosylated α-Amino Acid Synthesis by Addition Reaction of an Amino Acid Organozinc Reagent on Carbohydrate-Derived Aldehydes

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Noncationic dipeptide mimic oligomers as cell penetrating nonpeptides (CPNP).

scientific article published on October 2010

Novel 1H-Pyrrolo[3,2-c]quinoline Based 5-HT6 Receptor Antagonists with Potential Application for the Treatment of Cognitive Disorders Associated with Alzheimer's Disease

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Novel Cathepsin D Inhibitors Prevent the β-Secretase-Derived Intracellular Formation of a 12 kDa Potentially Amyloidogenic Product in Human Cells

Novel class of arylpiperazines containing N-acylated amino acids: their synthesis, 5-HT1A, 5-HT2A receptor affinity, and in vivo pharmacological evaluation

scientific article published on 13 February 2007

Novel preparation of N-protected amino acid active esters using 1,2,2,2-tetrachloroethyl carbonates

Occurrence of C-terminal residue exclusion in peptide fragmentation by ESI and MALDI tandem mass spectrometry

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On the central mechanism underlying ghrelin's chronic pro-obesity effects in rats: new insights from studies exploiting a potent ghrelin receptor antagonist

scientific article published in September 2009

On the significance of the C-terminal primary amide in cholecystokinin

scientific article published in 1993

On the use of carboxamidomethyl esters (cam esters) in the synthesis of model peptides. scope and limitations

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On-line synthesis of pseudopeptide library incorporating a benzodiazepinone turn mimic: biological evaluation on MC1 receptors

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Optically pure beta-substituted beta-hydroxy aspartates as glutamate transporter blockers

scientific article published in June 2003

Optimization of spiroimidazolidinone derivatives synthesis on solid phase using SynPhase™ Lanterns

Oxa-diketopiperazines: Access and Conformational Analysis of Potential Turn Inducers

Oxyfold: A Simple and Efficient Solid-Supported Reagent for Disulfide Bond Formation

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Oxyntomodulin (glucagon-37) and its C-terminal octapeptide inhibit gastric acid secretion

scholarly article by Claire Jarrousse published in August 1985

Oxyntomodulin and its (19–37) and (30–37) fragments inhibit histamine-stimulated gastric acid secretion in the conscious rat

scientific article published on 01 October 1991

Oxyntomodulin and its C-terminal octapeptide inhibit liquid meal-stimulated acid secretion

scientific article published in January 1986

Oxyntomodulin and related peptides control somatostatin secretion in RIN T3 cells

scientific article published on 01 November 1991

O–N-Acyl migration in N-terminal serine-containing peptides: mass spectrometric elucidation and subsequent development of site-directed acylation protocols

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P3-238

PEG as an alternative reaction medium in metal-mediated transformations

PEG3400–Cu2O–Cs2CO3: an efficient and recyclable microwave-enhanced catalytic system for ligand-free Ullmann arylation of indole and benzimidazole

Palatability Can Drive Feeding Independent of AgRP Neurons

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Palatability Can Drive Feeding Independent of AgRP Neurons

scholarly article by Raphaël G Denis published in April 2017

Palladium N-Heterocyclic Carbene Catalysts for the Ultrasound-Promoted Suzuki-Miyaura Reaction in Glycerol

scholarly article by Arturo Azua et al published 8 April 2013 in Advanced Synthesis & Catalysis

Palladium-Catalysed Cross-Coupling Reactions on Pyridazine Moieties

Palladium-Catalyzed Cross-Coupling Reactions on Pyridazine Moieties

Palladium-catalyzed cascade allylation/carbopalladation/cross coupling: a novel three-component reaction for the synthesis of 3,3-disubstituted-2,3-dihydrobenzofurans

scholarly article by Magali Szlosek-Pinaud et al published November 2003 in Tetrahedron Letters

Parallel Synthesis of New β-Amino Esters via Conjugate Nucleophilic Additions

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Parallel Synthesis of New β2-Amino Esters via Conjugate Nucleophilic Additions

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Parallel and Mixture Combined Approach: Rapid Cheap Synthesis and Characterization of a 4096-Tripeptides Library

Parallel solid-phase synthesis and characterization of new sulfonamide and carboxamide proline derivatives as potential CNS agents

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Parallel synthesis of a lipopeptide library by hydrazone-based chemical ligation

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Peptide Bond Formation Using Polymer-Bound BOP

article by Sorin V. Filip et al published May 2004 in European Journal of Organic Chemistry

Peptide Mechanosynthesis by Direct Coupling of N -Protected α-Amino Acids with Amino Esters

Peptide and pseudopeptide analogues of cholecystokinin, chemical modifications of the met28-gly29 region

Peptide hormones as prohormones

Peptide neurotoxins that affect voltage-gated calcium channels: a close-up on ω-agatoxins

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Peptide synthesis: ball-milling, in solution, or on solid support, what is the best strategy?

Peptide-poly(L-lysine citramide) conjugates and their in vitro anti-HIV behavior

scientific article published on April 2009

Pharmacologic antagonism of ghrelin receptors attenuates development of nicotine induced locomotor sensitization in rats

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Pharmacological activity of cholecystokinin analogues modified in the Met28-Gly29 region

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Pharmacological and Biochemical Characterization of TLQP-21 Activation of a Binding Site on CHO Cells

scientific article published on 30 March 2017

Pharmacological characterization of new cholecystokinin analogues.

scientific article published in November 1992

Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity

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Pharmacological profile of a new peptidic gastrin antagonist

scientific article published on September 1986

Pharmacological studies on CCKB receptors in guinea pig synaptoneurosomes

scientific article published in May 1992

Phenethyl ester derivative analogs of the C-terminal tetrapeptide of gastrin as potent gastrin antagonists

scientific article published on 01 November 1986

Phenylethylamide derivatives of the C-terminal tetrapeptide of gastrin

scientific article published on 01 November 1986

Poly(ethylene glycol) as a Reaction Matrix in Platinum- or Gold-Catalyzed Cycloisomerization: A Mechanistic Investigation

Poly(ethylene glycol) as reaction medium for mild Mizoroki–Heck reaction in a ball-mill

Poly(ethylene glycol) as solvent and polymer support in the microwave assisted parallel synthesis of aminoacid derivatives

Poly(ethylene glycol)-based ionic liquids: properties and uses as alternative solvents in organic synthesis and catalysis.

scientific article published on 05 December 2013

Poly(ethylene glycol)s as grinding additives in the mechanochemical preparation of highly functionalized 3,5-disubstituted hydantoins.

scientific article published on 4 January 2017

Poly(ethylene) glycols and mechanochemistry for the preparation of bioactive 3,5-disubstituted hydantoins

scholarly article in RSC Advances, vol. 6 no. 43, 2016

Poly(ethyleneglycol) in electrospray ionization (ESI) mass spectrometry

Polyethylene glycol (PEG) as polymeric support and phase-transfer catalyst in the soluble polymer liquid phase synthesis of α-amino esters

Post-synthesis incorporation of a lipidic side chain into a peptide on solid support

scientific article

Post-synthesis modification of aspartyl or glutamyl residue side-chains on solid support

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Potent spinal analgesia elicited through stimulation of NTS2 neurotensin receptors

scientific article

Preclinical comparison of Al18F- and 68Ga-labeled gastrin-releasing peptide receptor antagonists for PET imaging of prostate cancer

scientific article

Preliminary selection of 5-HT1Areceptor ligands by TLC on plates impregnated with synthetic peptides

scholarly article by Paweł Zajdeł et al published February 2002 in Journal of Planar Chromatography - Modern TLC

Preliminary study on application of impregnated synthetic peptide TLC stationary phases for the pre-screening of 5-HT1A ligands.

scientific article

Preparation of Chiral Amino Esters by Asymmetric Phase-Transfer Catalyzed Alkylations of Schiff Bases in a Ball Mill

Preparation of NHC–ruthenium complexes and their catalytic activity in metathesis reaction

scholarly article by Evelina Colacino et al published March 2007 in Coordination Chemistry Reviews

Preparation of Poly(Ethylene Glycol) Sulfonamide: Synthesis of N-Supported β-Aminoesters via the Aza-Baylis−Hillman Reaction

Preparation of Some Thiazolyl Hydrazone Derivatives and Evaluation of Their Antibacterial Activities

Preparation of enantioenriched iodinated pyrrolinones by iodocyclization of α-amino-ynones

Prevention of Spontaneous Tumors of Aged Mice by Immunopharmacologic Manipulation: Study of Immune Antitumor Mechanisms2

scientific article published on 01 June 1981

Probing the importance of π-stacking interactions in DNA-templated self-assembly of bisfunctionalized guanidinium compounds

Progressive Seizure Aggravation in the Repeated 6-Hz Corneal Stimulation Model Is Accompanied by Marked Increase in Hippocampal p-ERK1/2 Immunoreactivity in Neurons

scientific article published on 16 December 2016

Proteolytic activity and expression of the 20S proteasome are increased in psoriasis lesional skin

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Pyrido-imidazodiazepinones as a new class of reversible inhibitors of human kallikrein 7.

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Quality Control of Solid-Phase Synthesis by Mass Spectrometry

Quality control of solid-phase synthesis by mass spectrometry

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Quantitative MALDI-MS Binding Assays: An Alternative to Radiolabeling.

scientific article

Quantitative determination of rocuronium in human plasma by liquid chromatography-electrospray ionization mass spectrometry

scientific article

REGIOSELECTIVE REACTION OF UNPROTECTED SUGARS WITH URETHANEN-CARBOXYANHYDRIDES FOR THE SYNTHESIS OF NEW SURFACTANTS

Rapid sensing of circulating ghrelin by hypothalamic appetite-modifying neurons

scientific article published on 7 January 2013

Rapid solid phase synthesis of α-amino acids

Reactivity Study of 1H-Thieno[3,2-d][1,3]oxazine-2,4-dione toward the Synthesis of Bicyclic 3,4-Dihydro-1H-thieno[3,2-e][1,4]diazepine-2,5-dione Analogues

Reactivity of UNCAs with Grignard reagents

Recent Advances in the Synthesis of Hydantoins: The State of the Art of a Valuable Scaffold

scientific article

Recent Developments in Ghrelin Receptor Ligands

Recent developments in ghrelin receptor ligands

scientific article

Receptor-Ligand Interaction Measured by Inductively Coupled Plasma Mass Spectrometry and Selenium Labeling

scientific article published on 08 November 2018

Recycling the versatile Pipecolic linker

scientific article published on September 2010

Reduced peptide bond pseudopeptide analogues of neurotensin: binding and biological activities, and in vitro metabolic stability

scientific article

Reduction phenomenon in frit fast-atom bombardment mass spectrometry

scholarly article by Jean-Louis Aubagnac et al published 1995 in Rapid Communications in Mass Spectrometry

Regio-Controlled Nucleophilic Attack of 3-Thiaisatoic Anhydride by α-Amino Acids: One-Pot Synthesis of 3-(2-Thienyl)imidazolidine-2,4-dione and 3,4-Substituted Thieno[2,3-e][1,4]diazepine-2,5-dione Analogues

Regioselective and sequential reactivity of activated 2,5-diketopiperazines

Regulation of ERK1/2 activity by ghrelin-activated growth hormone secretagogue receptor 1A involves a PLC/PKCvarepsilon pathway

scientific article published in June 2006

Replacement of a Proline with Silaproline Causes a 20-Fold Increase in the Cellular Uptake of a Pro-Rich Peptide

scientific article published in 2006

Resolution of protected silaproline for a gram scale preparation

scientific article published on 15 October 2011

Ribbon-like Foldamers for Cellular Uptake and Drug Delivery

scientific article

Ring-closing metathesis in aqueous micellar medium

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Ring-closing metathesis in glycerol under microwave activation

Robust helix formation in a new family of oligoureas based on a constrained bicyclic building block.

scientific article

SIDE REACTIONS IN PEPTIDE SYNTHESIS

SIDE REACTIONS IN PEPTIDE SYNTHESIS

SYNTHESIS OF ANALOGS OF THE SERUM THYMIC NONAPEPTIDE, FACTEUR THYMIQUE SERIQUE (FTS) Part I

SYNTHESIS OF ANALOGS OF THE SERUM THYMIC NONAPEPTIDE, “FACTEUR THYMIQUE SERIQUE” (FTS) Part II

scientific article published on 01 October 1980

Saponification of esters of chiralα-amino acids anchored through their amine function on solid support

scholarly article by Sonia Cantel published in May 2004

Selective C-acylation of 2-aminoimidazo[1,2-a]pyridine: application to the synthesis of imidazopyridine-fused [1,3]diazepinones

scientific article

Selective [3 + 2] Huisgen Cycloaddition. Synthesis ofTrans-Disubstituted Triazolodiazepines fromAza-Baylis−Hillman Adducts

Selective homodimerization of unprotected peptides using hybrid hydroxydimethylsilane derivatives

scholarly article in RSC Advances, vol. 6 no. 39, 2016

Selenazolidine: a selenium containing proline surrogate in peptide science

scientific article published on 10 August 2016

Sequencing Lys-N proteolytic peptides by ESI and MALDI tandem mass spectrometry

scientific article

Sequential aza-Baylis-Hillman/ring closing metathesis/aromatization as a novel route for the synthesis of substituted pyrroles

scientific article published in November 2004

Serotonin Dimers: Application of the Bivalent Ligand Approach to the Design of New Potent and Selective 5-HT1B/1DAgonists

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Si10Cu6N4 Cage Hexacoppersilsesquioxanes Containing N Ligands: Synthesis, Structure, and High Catalytic Activity in Peroxide Oxidations.

scientific article published on 29 November 2017

Side Reactions in Peptide Synthesis

Side reactions in peptide synthesis. 11. Possible removal of the 9-fluorenylmethyloxycarbonyl group by the amino components during coupling

Side reactions in peptide synthesis. 12. Hydrogenolysis of the 9-fluorenylmethyloxycarbonyl group

Side reactions in peptide synthesis. 8. On the phenacyl group in the protection of the .beta.-carboxyl function of aspartyl residues

Silaproline Helical Mimetics Selectively Form an All-transPPII Helix

Silaproline, a Silicon-Containing Proline Surrogate

Silica nanoparticles pre-spotted onto target plate for laser desorption/ionization mass spectrometry analyses of peptides

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Silicon-Containing Amino Acids: Synthetic Aspects, Conformational Studies, and Applications to Bioactive Peptides

scientific article published on 16 August 2016

Simple and Specific Grafting of Antibacterial Peptides on Silicone Catheters.

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Site-specific grafting on titanium surfaces with hybrid temporin antibacterial peptides

scientific article published on 07 March 2018

Solid Phase Synthesis of C-Terminal Peptide Aldehydes

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Solid Phase Synthesis of a Hydroxypyrrolidine Derivative and its Use in Solid Phase Peptide Synthesis as Constrained Statine Mimic

article by Pascal Verdié et al published 9 March 2007 in International Journal of Peptide Research and Therapeutics

Solid phase synthesis of chiral 3-substituted quinazoline-2,4-diones

Solid phase synthesis of mono- or disubstituted arginine containing peptides from an isothiocitrulline precursor

Solid phase synthesis of peptide aldehydes

Solid-Phase Cross-Linking (SPCL): a new tool for protein structure studies

scientific article

Solid-Phase Synthesis of Aryl-Alkylamine Derivatives Using Protected Aminoalcohol Building Blocks on SynPhaseTM Lanterns

Solid-Phase Synthesis of Arylpiperazine Derivatives and Implementation of the Distributed Drug Discovery (D3) Project in the Search for CNS Agents

Solid-Phase Synthesis of Isocoumarins: A Traceless Halocyclization Approach

Solid-Supported Synthesis and 5-HT7 /5-HT1A Receptor Affinity of Arylpiperazinylbutyl Derivatives of 4,5-dihydro-1,2,4-triazine-6-(1H)-one

scientific article published on 12 February 2015

Solid-phase peptide synthesis of human(Nle-27)-oxyntomodulin

scientific article published on 01 May 1986

Solid-phase synthesis of 3,7-disubstituted perhydro-1,4-diazepine-2,5-diones from amino acids and β-amino acids

article published in 2001

Solid-phase synthesis of 4-methylcarboxy-1,4-benzodiazepine-2,5-diones

scientific article published on 27 September 2008

Solid-phase synthesis of 5-arylhistidines via a microwave-assisted Suzuki–Miyaura cross-coupling

Solid-phase synthesis of arginine-containing peptides and fluorogenic substrates using a side-chain anchoring approach

scientific article published in November 2004

Solid-phase synthesis of dipeptidic and pseudo-dipeptidic potential NOS inhibitors through a side-chain anchoring approach

Solid-phase synthesis of α-amino acids by radical addition to adehydroalanine derivative

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Solid-supported synthesis, molecular modeling, and biological activity of long-chain arylpiperazine derivatives with cyclic amino acid amide fragments as 5-HT(7) and 5-HT(1A) receptor ligands

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Soluble Polymer Supported Synthesis of α-Amino Acid Derivatives

scientific article published on 01 March 2000

Solution and Solid-Supported Synthesis of 3,4,5-Trisubstituted 1,2,4-Triazole-Based Peptidomimetics

Solution and Solid-Supported Synthesis of 3,4,5-Trisubstituted 1,2,4-Triazole-Based Peptidomimetics

scientific article published in 2003

Solvent-Free Microwave-Assisted Suzuki-Miyaura Coupling Catalyzed by PEPPSI-iPr

Solvent-Free Synthesis of Peptides

Solvent-Free Synthesis of Peptides

scientific article published on 01 January 2009

Solvent-free synthesis of hydrazones and their subsequent N-alkylation in a Ball-mill

Solvent-free synthesis of nitrones in a ball-mill

Solvent-free synthesis of unsaturated amino esters in a ball-mill

Solventless Mechanosynthesis of N-Protected Amino Esters

Solventless Synthesis of N-Protected Amino Acids in a Ball Mill

Sol–gel synthesis of collagen-inspired peptide hydrogel

Somatostatin enhances the inhibitory effect of oxyntomodulin and its C-terminal octapeptide on acid secretion

scientific article published on 01 January 1986

Some of the amino acid chemistry going on in the Laboratory of Amino Acids, Peptides and Proteins.

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Sonochemistry in non-conventional, green solvents or solvent-free reactions

Spectroscopic analysis of synthetic PrP helix2-binding peptide constructs

scientific article published in January 2009

Spinal NTS2 receptor activation reverses signs of neuropathic pain

scientific article published on 11 June 2013

Spiroimidazolidinone library derivatives on SynPhase lanterns

scientific article

Static secondary ion mass spectrometry to monitor solid-phase peptide synthesis

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Stereocontrolled Synthesis of 2,4-Diamino-3-hydroxyacids Starting from Diketopiperazines: A New Route for the Preparation of Statine Analogues

scientific article published in 2007

Stereoselective Synthesis of β-(5-Arylthiazolyl) α-Amino Acids and Use in Neurotensin Analogues

Stereoselective divergent synthesis of 1,2-aminoalcohol-containing heterocycles from a common chiral nonracemic building block

scholarly article by Pierre-Yves Géant et al published January 2016 in Tetrahedron: Asymmetry

Stereoselective ring contraction of 2,5-diketopiperazines: An innovative approach to the synthesis of promising bioactive 5-membered scaffolds

article published in 2010

Stereoselective synthesis of allyl- and homoallylglycines

Stereoselective synthesis of original spirolactams displaying promising folded structures.

scientific article published on 13 June 2013

Stereoselective synthesis of unsaturated α-amino acids

scientific article published on 26 February 2015

Straightforward Synthesis of Chiral Silylated Amino Acids through Hydrosilylation

Straightforward strategy to substitute amide bonds by 1,2,3-triazoles in peptaibols analogs using Aibψ[Tz]-Xaa dipeptides

scientific article published on 18 March 2015

Structural elucidation of the β-turn inducing (S)-[3-amino-4-oxo-2,3-dihydro-5H-benzo[b][1,4]thiazepin-5-yl] acetic acid (DBT) motif

Structural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix)

scientific article

Structure of cholecystokinin receptor binding sites and mechanism of activation/inactivation by agonists/antagonists.

scientific article published in December 2002

Structure-Activity Relationships of JMV4463, a Vectorized Cathepsin D Inhibitor with Antiproliferative Properties: The Unique Role of the AMPA-Based Vector

scientific article published on 07 December 2015

Structure-activity relationships of C-terminal tri- and tetrapeptide fragments that inhibit gastrin activity

scientific article published on 01 March 1985

Structure-activity relationships of novel peptide agonists of the human bradykinin B2 receptor

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Structure-activity relationships of phenyl-furanyl-rhodanines as inhibitors of RNA polymerase with antibacterial activity on biofilms

scientific article published in August 2007

Study of a lipophilic captopril analogue binding to angiotensin I converting enzyme

scientific article published on 01 February 2010

Study of the states and populations of the rat pancreatic cholecystokinin receptor using the full peptide antagonist JMV 179

scientific article published on 01 March 1993

Sulfonamides with the N-alkyl-N'-dialkylguanidine moiety as 5-HT7 receptor ligands.

scientific article published on 13 June 2009

Supported oligomethionine sulfoxide and Ellman's reagent for cysteine bridges formation

scientific article published on 12 September 2012

Supported synthesis of oxoapratoxin A.

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Switchable polymer-grafted mesoporous silica's: from polyesters to polyamides biosilica hybrid materials

Synthese d'esters “actives” d'acides amines avec l'hexachlorocyclotriphosphatriazene

Syntheses and biological activities of bombesin analogs modified in the C-terminal dipeptide part

Syntheses and biological activities of potent bombesin receptor antagonists

scientific article published on March 1999

Synthesis and Anti-HIV Activity of d-peptide Analogs as HIV Fusion Inhibitors

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Synthesis and Biological Evaluation of New CRH Analogues

scientific article published on 28 June 2010

Synthesis and Characterization in Vitro and in Vivo of (l)-(Trimethylsilyl)alanine Containing Neurotensin Analogues.

scientific article published on 8 September 2015

Synthesis and TGF-β Receptor Binding Inhibition of Multibranched Compounds

Synthesis and activity of HIV protease inhibitors

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Synthesis and analgesic effects of novel β2-tryptophan hexapeptide analogs

Synthesis and anti-Candida activity of novel 2-hydrazino-1,3-thiazole derivatives

scientific article published on 23 January 2013

Synthesis and antibacterial activity of tert-butyl [1-benzyl-2[(4-aryl-2-thiazolyl)hydrazono]ethyl]carbamate derivatives

scientific article published in June 2007

Synthesis and antitumor evaluation of some nitrosourea and nitrogen mustard amino acid derivatives

scientific article published on September 1984

Synthesis and biological activities of cholecystokinin analogues substituted in position 30 by 3-(1-naphthyl)-l-alanine [Nal(1)] or 3-(2-naphthyl)-l-alanine [Nal(2)]

Synthesis and biological activities of peptidomimetic analogues of compound A71623, a potent and selective CCK-A receptor agonist

Synthesis and biological activities of some cholecystokinin analogues substituted in position 29 by a β-alanine

scientific article published on 01 November 1989

Synthesis and biological activities of some pseudo-peptide analogs of tetragastrin: the importance of the peptide backbone

scientific article published on 01 December 1985

Synthesis and biological activity of 2-phenylethyl ester analogues of C-terminal heptapeptide of cholecystokinin modified in Trp 30 region

scientific article published in August 1991

Synthesis and biological activity of CCK peptides with antagonist activity for CCK-A-receptor

Synthesis and biological activity of glutamic acid derivatives

scientific article published in January 1998

Synthesis and biological activity of new peptide segments of gastrin exhibiting gastrin antagonist property

scientific article published on 01 December 1984

Synthesis and biological activity of nicotianamine and analogues.

scientific article published in January 2009

Synthesis and biological effects of c(Lys-Lys-Pro-Tyr-Ile-Leu-Lys-Lys-Pro-Tyr-Ile-Leu) (JMV2012), a new analogue of neurotensin that crosses the blood-brain barrier

scientific article

Synthesis and biological evaluation of C-terminal hydroxamide analogues of bombesin

scientific article published on April 1999

Synthesis and biological evaluation of bombesin constrained analogues

scientific article published on June 2000

Synthesis and biological evaluation of bradykinin B(1)/B(2) and selective B(1) receptor antagonists

scientific article published in June 2000

Synthesis and changes in affinity for NOP and opioid receptors of novel hexapeptides containing β(2)-tryptophan analogues

scientific article

Synthesis and characterization of a cyclooctapeptide analogue of ω-agatoxin IVB enhancing the activity of Cav2.1 calcium channels activity in cultured hippocampal neurons

scientific article published on 20 July 2012

Synthesis and characterization of bradykinin B(2) receptor agonists containing constrained dipeptide mimics

scientific article published on October 1999

Synthesis and in Vivo pharmacological profile of dimeric HOE 140 bradykinin antagonists

scholarly article

Synthesis and pharmacological evaluation of a new series of bombesin analogs

scholarly article

Synthesis and pharmacological in vitro and in vivo evaluations of novel triazole derivatives as ligands of the ghrelin receptor. 1.

scientific article published on 22 March 2007

Synthesis and post-synthetic modification of UiO-67 type metal-organic frameworks by mechanochemistry

Synthesis and reactivity of pyrrolo[3,2-d][1,3]oxazine-2,4-dione. Access to new pyrrolo[3,2-e][1,4]diazepine-2,5-diones

Synthesis and some pharmacological properties of 8-L-methionine-oxytocin

scientific article published on March 1979

Synthesis and some pharmacological properties of Z-Tyr(SO3H)-Met-Gly-Trp-Met-Asp(Phe-NH2)-OH, a 32-beta-aspartyl analogue of cholecystokinin (pancreozymin) 27-33.

scientific article published in May 1982

Synthesis and structure of symmetrical bicyclic hexapeptides bridged by metathesis reaction

scientific article published in September 2004

Synthesis of (R) and (S) enantiomers of Fmoc-protected 1,2,4-oxadiazole-containing β3-amino acids from Fmoc-(R)-β-HAsp(OtBu)-OH

Synthesis of (S)-N-Boc-3-Amino-2-Arylpropanol from Optically Active β-Amino Esters

Synthesis of 2,6-Disubstituted Piperidine-Bearing α-Amino Acid Side-Chains

Synthesis of 2,6-Disubstituted Piperidine-Bearing α-Amino Acid Side-Chains

Synthesis of 3,4,5-trisubstituted-1,2,4-triazoles

scientific article published on April 2010

Synthesis of C5-tetrazole derivatives of 2-amino-adipic acid displaying NMDA glutamate receptor antagonism

scientific article published on 13 August 2010

Synthesis of Chiral α-Amino-diazoketones on Solid Support: An Access to β-Homologated Amino Acid Derivatives

Synthesis of Cyclic Amino Acid Derivatives via Ring Closing Metathesis on a Poly(ethylene glycol) Supported Substrate

scientific article published on 01 October 2000

Synthesis of Enantiopure 1,2-Diaminobicyclo[2.2.2]octane Derivatives, C1-Symmetric Chiral 1,2-Diamines with a Rigid Bicyclic Backbone.

scientific article published on 15 February 2017

Synthesis of N- and side chain protected aspartyl and glutamyl aldehyde derivatives. Reinvestigation of the reduction of Weinreb amides

Synthesis of N-Boc-(R)-α-phenyl-γ-aminobutyric acid using an in situ diastereoselective protonation strategy

Synthesis of N-protected α-amino aldehydes from their morpholine amide derivatives

Synthesis of N-protected γ-amino-β-keto-esters from urethane N-carboxyanhydrides (UNCAs)

Synthesis of N-urethane protected α-alkyl-γ-amino-β-keto-esters from urethane N-carboxyanhydrides (UNCAs)

Synthesis of New Functionalized Cyclic Dipeptide

Synthesis of New Tetrazole-Substituted Pyroaminoadipic and Pipecolic Acid Derivatives

article published in 2005

Synthesis of New α-Heterocyclic α-Aminophosphonates

Synthesis of Novel Pyrrolo-[3,2-c]quinolines via Iron-Catalyzed Cross-Coupling Reaction of Grignard Reagents

Synthesis of Peptide Aldehydes

Synthesis of Phosphonic Analogues of 4-Hydroxyproline and 5-Hydroxypipecolic Acid

scientific article published in 2000

Synthesis of Pyrrolin-4-ones by Pt-Catalyzed Cycloisomerization in PEG under Microwaves

Synthesis of Structurally Diversified α-Substituted β-Amino Acids and Derivatives via Conjugate Radical Additions and Heck Reactions

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Synthesis of Substituted Imidazo[1,5-a]pyridines Starting from N-2-Pyridylmethylamides Using Lawesson’s Reagent and Mercury(II) Acetate

Synthesis of Thieno[3,2-e][1,4]diazepin-2-ones: Application of an Uncatalysed Pictet-Spengler Reaction

Synthesis of Various 3-Substituted 1,2,4-Oxadiazole-Containing Chiral β3- and α-Amino Acids from Fmoc-Protected Aspartic Acid

Synthesis of Various Chiral 1,2,4-Triazole-Containing α-Amino Acids from Aspartic or Glutamic Acids

Synthesis of Z-CCK-27-32-NH2, Z-Tyr(SO-3)-Met-Gly-Trp-Met-Asp-NH2, a cholecystokinin receptor antagonist and an inhibitor of gastrin-induced acid secretion

scientific article published in September 1985

Synthesis of a new hydrophilic poly(ethylene glycol)-ionic liquid and its application in peptide synthesis

article

Synthesis of a new insoluble polymer-supported chiral alcohol auxiliary and its first application to nucleophilic addition to ketenes.

scientific article published in August 2001

Synthesis of a novel pyrrolo-[3,2-c]quinoline N-oxide by aza-Baylis–Hillman adduct of o-nitrobenzaldehyde

Synthesis of an 8-Benzyl-4-(p-substituted-benzyl)-1,4,8-triazaspiro[4.5]decan-2-one Library on SynPhase TMLanterns

Synthesis of an IgG fragment decapeptide exhibiting phagocytosis stimulating activity of polymorphonuclear leucocytes

scientific article published on 01 July 1983

Synthesis of analogues of the Des-Phe-NH2C-terminal hexapeptide of cholecystokinin showing gastrin antagonist activity

scientific article published on 01 April 1986

Synthesis of chiral N-protected amino acid esters by the use of UNCAs

Synthesis of chiral N-protected α-amino aldehydes by reduction of N-protected N-carboxyanhydrides (UNCAs)

Synthesis of chiral N-protected β-amino alcohols by the use of UNCAs

Synthesis of chiral urethane N-alkoxycarbonyl tetramic acids from urethane N-carboxyanhydrides (UNCAs)

Synthesis of chiralα-amino aldehydes linked by their amine function to solid support

scholarly article by Sonia Cantel published in August 2004

Synthesis of cyanoketophosphoranes, precursors of β-amino-α-keto-esters from UNCAs

Synthesis of cyclic analogues of cholecystokinin highly selective for central receptors

Synthesis of cyclic peptides via O–N-acyl migration

article

Synthesis of cyclooctapeptides: constraints analogues of the peptidic neurotoxin, ω-agatoxine IVB—an experimental point of view

Synthesis of enantiomerically pure (3R,4R,5R)-4-hydroxy isoleucine lactone

Synthesis of enantiopure trans-N-Boc-3-aminobicyclo[2.2.2]octane-2-carboxylic acids and their bicyclic 1,3-amino alcohol derivatives via the [4+2] cycloaddition of 1,3-cyclohexadiene to a chiral β-nitroacrylate

Synthesis of gastrin antagonists, analogs of the C-terminal tetrapeptide of gastrin, by introduction of a .beta.-homo residue

scientific article published on 01 March 1989

Synthesis of gem-diamino derivatives on solid support

Synthesis of homopolypeptides with PPII structure

Synthesis of new racemic and optically active N-phosphonoalkyl bicyclic β-amino acids via the kabachnik-fields reaction as potential biologically active compounds

Synthesis of new tetrazole and triazole substituted pyroglutamic acid and proline derivatives

Synthesis of new triazole substituted pyroaminoadipic and pipecolic acid derivatives

Synthesis of novel multi-cationic PEG-based ionic liquids

Synthesis of novel poly(ethylene glycol) supported benzazepines: the crucial role of PEG on the selectivity of an intramolecular Heck reaction

article published in 2006

Synthesis of peptide T analogues

Synthesis of peptide alcohols on the basis of an O-N acyl-transfer reaction

scientific article published in January 2010

Synthesis of peptide aldehydes

scientific article published on January 2007

Synthesis of peptide aldehydes on solid support

Synthesis of peptide aldehydes on solid support using ozonolysis

Synthesis of peptide-grafted comb polypeptidesviapolymerisation of NCA-peptides

Synthesis of perhydrodiazepinones as new putative peptidomimetics

Synthesis of pyrrolidine-2,4-diones from urethane N-carboxyanhydrides (UNCAs)

Synthesis of the C-terminal octapeptide of pig oxyntomodulin. Lys-Arg-Asn-Lys-Asn-Asn-Ile-Ala: a potent inhibitor of pentagastrin-induced acid secretion

Synthesis of tritium labelled delta sleep-inducing peptide

scholarly article by Matthieu Giraud et al published 2001 in Journal of Labelled Compounds and Radiopharmaceuticals

Synthesis of tuftsin and postin by the combined use of Mtr and Pmc arginine side chain protections and OBg ester C-terminal protection

Synthesis of various 3-substituted 1,2,4-oxadiazole-containing chiral beta 3- and alpha-amino acids from Fmoc-protected aspartic acid

scientific article published in September 2003

Synthesis of α-Heterocyclic α-Aminophosphonates, Part II: Morpholine, Piperidine, Pyrrolidine, Tetrahydrofurylmethylamine, N-Benzyl-N-Methylamine, and Aniline Derivatives

Synthetic therapeutic peptides: science and market

scientific article published on 30 October 2009

Synthèse d'un O-glycodipeptide par allongement de la chaîne peptidique du côté N-terminal d'un glycosylaminoacide

scientific article published on 01 August 1976

Systemic Delivery of Tumor-Targeted Bax-Derived Membrane-Active Peptides for the Treatment of Melanoma Tumors in a Humanized SCID Mouse Model.

scientific article published on February 2017

Tandem mass spectrometry of amidated peptides

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The 1,2,4-triazole as a scaffold for the design of ghrelin receptor ligands: development of JMV 2959, a potent antagonist

scientific article published on 14 July 2012

The GHR-R antagonist JMV 2959 neither induces malaise nor alters the malaise property of LiCl in the adult male rat.

scientific article published on 19 October 2017

The Negishi Cross-Coupling in the Synthesis of Natural Products and Bioactive Molecules

The asymmetric synthesis of non-peptide CCK-A receptor agonists

The crystallographic structure of thermoNicotianamine synthase with a synthetic reaction intermediate highlights the sequential processing mechanism

scientific article

The design and synthesis of the high efficacy, non-peptide CCK 1 receptor agonist PD 170292

scientific article published on 01 June 2000

The effect of gastrin on growth of human stomach cancer cells

scientific article published on May 1992

The epimerization of peptide aldehydes—a systematic study

scholarly article by Cécile Ganneau published in January 2006

The importance of the amino acid in position 27 of cholecystokinin in determining its biological activity on pancreatic acini

scientific article published in July 1980

The importance of the amino acid in position 32 of cholecystokinin in determining its interaction with cholecystokinin receptors on pancreatic acini

scientific article

The influence of an ethylene spacer on the 5-HT(1A) and 5-HT(2A) receptor affinity of arylpiperazine derivatives of amides with N-acylated amino acids and 3-differently substituted pyrrolidine-2,5-diones

scientific article

The influence of gastrin and/or cholecystokinin antagonists on the proliferation of three human astrocytic tumor cell lines

scientific article published in October 1996

The iodolactone approach to enantiopure oxiranes of constrained chiral cyclic β-amino acids

article by Olivier Songis et al published September 2008 in Tetrahedron: Asymmetry

The novel nonapeptide acein targets angiotensin converting enzyme in the brain and induces dopamine release

scientific article published on 8 March 2016

The pipecolic linker—an acid-labile handle for derivatization of secondary amines on a solid-support. Part 3

article by Paweł Zajdel et al published February 2013 in Tetrahedron Letters

The role of aspartyl-rich pentapeptides in comparative complexation of actinide(iv) and iron(iii). Part 1

The role of the Asp-32 residue of cholecystokinin in gastric acid secretion and gastrin receptor recognition

scientific article published on 01 March 1983

The use of N-urethane-protected N-carboxyanhydrides (UNCAs) in amino acid and peptide synthesis

scientific article published in March 1995

Thiazole-Based γ-Building Blocks as Reverse-Turn Mimetic to Design a Gramicidin S Analogue: Conformational and Biological Evaluation

scientific article published on 25 March 2014

Thieno[3,2-e]diazepinediones and 3-thienylimidazolidinediones syntheses: regio-controlled ring opening of thiaisatoic anhydride by alpha-amino acids.

scientific article published in January 2009

Tof-SIMS Analysis of Polymer Bound Fmoc-protected Peptides

article by C Drouot et al published April 1997 in Tetrahedron Letters

Torquoselective Nazarov Cyclization Mediated by a Chiral Sulfoxide: First Enantioselective Synthesis of two Known Anticancer Agents

Toward Diels−Alder Reactions on a Solid Support Using Polymer BoundN-Substituted 3-Hydroxy-4,4-dimethyl-2-pyrrolidinone Acrylate Derivatives

Toward potent ghrelin receptor ligands based on trisubstituted 1,2,4-triazole structure. 2. Synthesis and pharmacological in vitro and in vivo evaluations

scientific article

Towards a Selective Boc Deprotection on Acid Cleavable Resin

Towards a selective Boc deprotection on acid cleavable Wang resin

Transannular Rearrangement of Activated Lactams: Stereoselective Synthesis of Substituted Pyrrolidine-2,4-diones from Diketopiperazines

article published in 2007

Transannular rearrangement of activated 2,5-diketopiperazines: a key route to original scaffolds

Triazole GHS-R1a antagonists JMV4208 and JMV3002 attenuate food intake, body weight, and adipose tissue mass in mice.

scientific article published on 20 June 2014

Trisubstituted 1,2,4-triazoles as ligands for the ghrelin receptor: On the significance of the orientation and substitution at position 3

scientific article published in 2008

Turning Peptide Sequences into Ribbon Foldamers by a Straightforward Multicyclization Reaction

scientific article published on 23 September 2015

Turning Peptide Sequences into Ribbon Foldamers by a Straightforward Multicyclization Reaction

Turning peptides in comb silicone polymers

scientific article

Two key chiral intermediates in a new 4-hydroxyisoleucine synthesis

scientific article published on 01 August 2000

Ultrasounds in Melted Poly(ethylene glycol) Promote Copper-Catalyzed Cyanation of Aryl Halides with K4[Fe(CN)6]

scientific article published on 01 March 2014

Unambiguous and Controlled One-Pot Synthesis of Multifunctional Silica Nanoparticles

article published in 2016

Unprecedented Chain-Length-Dependent Conformational Conversion Between 11/9 and 18/16 Helix in α/β-Hybrid Peptides

scientific article published on 26 September 2014

Unprecedented directed oxidative cross-coupling of sulfahydantoins with aldehydes via a radical sulfonate–sulfinate conversion

Unraveling the synthesis of homoleptic [Ag(N,N-diaryl-NHC)2]Y (Y = BF4, PF6) complexes by ball-milling

article published in 2016

Unusual behavior of gem-diamino peptides in fast atom bombardment and electrospray ionization mass spectrometry

Urethane N-carboxyanhydrides from beta-amino acids

scientific article published in October 2001

Use of Molecular Modeling to Design Selective NTS2 Neurotensin Analogues.

scientific article published on 3 April 2017

Use of coated capillaries for the electrophoretic separation of stereoisomers of a growth hormone secretagogue

scientific article published in November 2009

Use of ozonolysis in the synthesis of C-terminal peptide aldehydes on solid support

Utilization of charge and mass labeling for the structural identification of heterocyclic quaternary salts by mass spectrometry

Utrophin localization in normal and dystrophin-deficient heart

article

Valuable Versatile Reactivity of Thiaisatoic Anhydrides: Expedient SolidPhase Synthesis of Thieno[1,4]diazepine-2,5-diones

Variations in Dystrophin Complex in Red and White Caudal Muscles from Torpedo marmorata

article by Mar Royuela et al published July 2001 in Journal of Histochemistry and Cytochemistry

Vitamin E protection of obesity-enhanced vascular calcification in uremic rats

scientific article

[15N]-Isotopic labeling: a suitable tool to study the reactivity of bis lactams

[2-(tert-Butylcarbonylmethylamino)phenyl]acetic acid

alpha,alpha'-disubstituted amino acids with silylated side chains as lipophilic building blocks for the synthesis of peptaibol analogues

scientific article published in July 2008

aza-Baylis-Hillman reaction

scientific article published on January 2009

cis-Apa: A Practical Linker for the Microwave-Assisted Preparation of Cyclic Pseudopeptides via RCM Cyclative Cleavage

α-tocopherol and α-tocopheryl phosphate interact with the cannabinoid system in the rodent hippocampus

scientific article published on 4 August 2011

β-Trimethylsilylethanesulfonyl Chloride

“Carba” peptide bond surrogates: synthesis of Boc--Leu-…(CH2-CH2)--Phe-OH and Boc-Leu-ψ-(CH2-CH2)--Phe-OH through a horner-emmons reaction

scientific article

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