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List of works by Francis J. McMahon

A Novel Mixture Model to Estimate the Time to Drug Effect Onset and Its Association with Covariates

scientific article

A Success at the End of an Era, and a Glimpse of Things to Come

A Success at the End of an Era, and a Glimpse of Things to Come

A functional alternative splicing mutation in human tryptophan hydroxylase-2.

scientific article

A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation

scientific article published on 12 September 2012

A genome-wide association study of amygdala activation in youths with and without bipolar disorder

scientific article

A network-based approach to prioritize results from genome-wide association studies

scientific article

A novel, heritable, expanding CTG repeat in an intron of the SEF2-1 gene on chromosome 18q21.1.

scientific article published on October 1997

A population-specific reference panel empowers genetic studies of Anabaptist populations

scientific article

A rare truncating mutation in ADH1C (G78Stop) shows significant association with Parkinson disease in a large international sample

scientific article published in January 2005

A tree-based model for allele-sharing-based linkage analysis in human complex diseases.

scientific article published in February 2006

Additional, physically ordered markers increase linkage signal for bipolar disorder on chromosome 18q22

scientific article published on 01 February 2003

Amish revisited: next-generation sequencing studies of psychiatric disorders among the Plain people

scientific article

An Integrative Genomic Study Implicates the Postsynaptic Density in the Pathogenesis of Bipolar Disorder

scientific article

Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder.

scientific article published on 31 May 2018

Apparent replication of suggestive linkage on chromosome 16 in the NIMH genetics initiative bipolar pedigrees

scientific article published in May 2002

Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report

scientific article published on 19 June 2013

Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression

scientific article published in July 2007

Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort

scientific article

Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.

scientific article published on 9 November 2017

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

scientific article published on 16 March 2020

Association study of 83 candidate genes for bipolar disorder in chromosome 6q selected using an evidence-based prioritization algorithm

scientific article

Association study of Wnt signaling pathway genes in bipolar disorder

scientific article

Association study of phosphodiesterase genes in the Sequenced Treatment Alternatives to Relieve Depression sample

scientific article

Association study of serotonin pathway genes in attempted suicide

scientific article

Attempted Suicide and Alcoholism in Bipolar Disorder: Clinical and Familial Relationships

scientific article published on 01 December 2000

Attempted Suicide in Bipolar Disorder Pedigrees: Evidence for Linkage to 2p12

article

Author Correction: A population-specific reference panel empowers genetic studies of Anabaptist populations.

scientific article published on 25 April 2018

Bcl-2 polymorphism influences gray matter volume in the ventral striatum in healthy humans

scientific article published on 09 July 2009

Bipolar disorder as a phenotype in genetic studies

Brain-derived neurotrophic factor ( BDNF) gene: no major impact on antidepressant treatment response

scientific article published on 23 February 2009

Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients.

scientific article published on 06 July 2012

Can long-range microsatellite data be used to predict short-range linkage disequilibrium?

scientific article

Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy

scientific article published on February 2013

Candidate endophenotypes for genetic studies of suicidal behavior

scientific article published on 7 February 2009

Case-control association study of TGOLN2 in attempted suicide

scientific article published on July 2010

Circadian genes and lithium response in bipolar disorders: associations with PPARGC1A (PGC-1α) and RORA.

scientific article published on 21 June 2016

Clinical and genetic validity of quantitative bipolarity

scientific article published on 16 September 2019

Clinically Useful Genetic Markers of Antidepressant Response: How Do We Get There From Here?

scientific article

Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm

scientific article published on October 2008

Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q

scientific article

Coming to grips with complex disorders: genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics

scientific article published on June 2010

Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder.

scientific article published on 29 April 2013

Common and rare variant analysis in early-onset bipolar disorder vulnerability

scientific article published on 11 August 2014

Common and rare variants of DAOA in bipolar disorder

scientific article published on October 2009

Common genetic variants influence human subcortical brain structures

scientific article

Common genetic variation in the indoleamine-2,3-dioxygenase genes and antidepressant treatment outcome in major depressive disorder.

scientific article published on 26 January 2012

Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms.

scientific article

Convergent genome wide association results for bipolar disorder and substance dependence

scientific article published in March 2009

Corpus callosum size is highly heritable in humans, and may reflect distinct genetic influences on ventral and rostral regions

scientific article

Correction: Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression

scientific article published on 05 March 2019

Cutaneous cryptococcosis without evidence of systemic involvement

scientific article

Defining haplotype blocks and tag single-nucleotide polymorphisms in the human genome

scientific article published on 17 December 2003

Defining the phenotype in human genetic studies: forward genetics and reverse phenotyping

scientific article

Detecting significant genotype-phenotype association rules in bipolar disorder: market research meets complex genetics

article

Diagnostic reliability of bipolar II disorder

scientific article published in August 2002

Do participants in genome sequencing studies of psychiatric disorders wish to be informed of their results? A survey study

scientific article

Dr. McMahon Replies ⬇️

scientific article published on 01 March 2008

Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder

scientific article published on 29 November 2018

Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.

scientific article published on 3 January 2012

Erratum to “Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder”, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics”, April 1; 156(3):370-378

article

Evidence for association of bipolar disorder to haplotypes in the 22q12.3 region near the genes stargazin, IFT27 and parvalbumin

scientific article published on 4 October 2012

Evidence of association between bipolar disorder and Citron on chromosome 12q24.

scientific article published in September 2005

Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder

scientific article published on December 2008

Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression

scientific article published on 14 December 2018

Familial aggregation of postpartum mood symptoms in bipolar disorder pedigrees

scientific article published in February 2008

Familial aggregation of psychotic symptoms in a replication set of 69 bipolar disorder pedigrees

scientific article published in January 2003

Familial variation in episode frequency in bipolar affective disorder

scientific article published in July 2005

Familiality of Polarity at Illness Onset in Bipolar Affective Disorder

article

Family-based association study of Neuregulin 1 with psychotic bipolar disorder

scientific article

Fever therapy: an educational intervention for parents

scientific article

Findings in an independent sample support an association between bipolar affective disorder and the G72/G30 locus on chromosome 13q33

scientific article published on 01 January 2004

Frequency Finder: a multi-source web application for collection of public allele frequencies of SNP markers

scientific article published on 22 January 2004

From genetics to biology: advancing mental health research in the Genomics ERA

scientific article published on 04 June 2019

G72/G30 in schizophrenia and bipolar disorder: review and meta-analysis

scientific article

Gene expression and genetic variation data implicate PCLO in bipolar disorder

scientific article

Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1.

scientific article

Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients

scientific article published on 18 March 2009

Genetic association mapping at the crossroads: which test and why? Overview and practical guidelines

scientific article

Genetic association studies in mood disorders: issues and promise

scientific article

Genetic association studies in psychiatry: time for pay-off

scientific article published on 22 February 2016

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

scientific article published on February 2016

Genetic linkage and association studies in bipolar affective disorder: a time for optimism

scientific article published on November 2003

Genetic markers of suicidal ideation emerging during citalopram treatment of major depression

scientific article

Genetic pleiotropy between mood disorders, metabolic, and endocrine traits in a multigenerational pedigree

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

scientific article published on 21 January 2016

Genetic variation in HTR2A influences serotonin transporter binding potential as measured using PET and [11C]DASB.

scientific article published on 05 January 2010

Genetic variation in cholinergic muscarinic-2 receptor gene modulates M2 receptor binding in vivo and accounts for reduced binding in bipolar disorder.

scientific article

Genetics of Bipolar Disorder

article

Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder

scientific article

Genome scan of a second wave of NIMH genetics initiative bipolar pedigrees: chromosomes 2, 11, 13, 14, and X.

scientific article published in May 2003

Genome scan of the fifty-six bipolar pedigrees from the NIMH genetics initiative replication sample: chromosomes 4, 7, 9, 18, 19, 20, and 21.

scientific article published on August 2003

Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder

scientific article

Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes

scientific journal article

Genome-wide association studies of antidepressant outcome: a brief review

scientific article

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

scientific article

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

article

Genome-wide association study of bipolar disorder in European American and African American individuals

scientific article

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

scientific article published in June 2021

Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression

scientific article published on 11 November 2019

Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients

scientific article

Genome-wide association study of suicide attempts in mood disorder patients

scientific article

Genome-wide linkage scan of 98 bipolar pedigrees and analysis of clinical covariates.

scientific article published on 15 May 2007

Genome-wide parametric linkage analyses of 644 bipolar pedigrees suggest susceptibility loci at chromosomes 16 and 20

scientific article published on August 2008

Genome-wide scan and conditional analysis in bipolar disorder: evidence for genomic interaction in the National Institute of Mental Health genetics initiative bipolar pedigrees

scientific article published in December 2003

Genome-wide scan of bipolar disorder in 65 pedigrees: supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12

article

Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1.

scientific article published on 25 September 2012

Genomewide linkage analyses of bipolar disorder: a new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative.

scientific article

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

scientific article published on 8 August 2017

Genomic survey of bipolar illness in the NIMH genetics initiative pedigrees: A preliminary report

article

Genotype-phenotype association mining in bipolar disorder: market research meets complex genetics

article

Genotype-phenotype studies in bipolar disorder showing association between the DAOA/G30 locus and persecutory delusions: a first step toward a molecular genetic classification of psychiatric phenotypes

scientific article published in November 2005

High frequencies of de novo CNVs in bipolar disorder and schizophrenia

scientific article published on December 2011

Hyperactivity following posterior cortical injury in lateralized, sensitive to lesion size and independent of the nigrostriatal dopamine system

article

Identification of common variants associated with human hippocampal and intracranial volumes

scientific article published on 15 April 2012

Identity-by-descent filtering as a tool for the identification of disease alleles in exome sequence data from distant relatives

scientific article

In vivo radioligand binding to translocator protein correlates with severity of Alzheimer's disease.

scientific article published on 17 June 2013

Inconsistent designs of association studies: a missed opportunity

scientific article published in September 2003

Increased gene expression of diacylglycerol kinase η in bipolar disorder

scientific article

Increased levels of a mitochondrial DNA deletion in the brain of patients with bipolar disorder

scientific article published in November 1997

Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 1, 6, 8, 10, and 12.

scientific article published in May 1997

Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 4, 7, 9, 18, 19, 20, and 21q.

scientific article published on May 1997

Initial genome screen for bipolar disorder in the NIMH genetics initiative pedigrees: chromosomes 2, 11, 13, 14, and X.

scientific article published in May 1997

Initial genomic scan of the NIMH genetics initiative bipolar pedigrees: Chromosomes 3, 5, 15, 16, 17, and 22

article

Integrating clinical and laboratory data in genetic studies of complex phenotypes: A network-based data management system

article by Francis J. McMahon et al published 8 May 1998 in American Journal of Medical Genetics Part A

Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling ⬇️

scientific article published on March 8, 2011

Introduction

Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study

It is time to take a stand for medical research and against terrorism targeting medical scientists

scientific article

Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin

scientific article published in August 2004

Linkage of bipolar affective disorder to chromosome 18 markers in a new pedigree series.

scientific article published in December 1997

Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigrees

scientific article published in July 2004

Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.

scientific article

Microduplications of 16p11.2 are associated with schizophrenia

scientific article

Mitochondrial DNA Sequence Diversity in Bipolar Affective Disorder

scientific article published on 01 July 2000

Molecular genetic overlap in bipolar disorder, schizophrenia, and major depressive disorder

scientific article

Mood-incongruent psychotic features in bipolar disorder: familial aggregation and suggestive linkage to 2p11-q14 and 13q21-33.

scientific article published on February 2007

NEDD4L on human chromosome 18q21 has multiple forms of transcripts and is a homologue of the mouse Nedd4-2 gene.

scientific article

Neither single-marker nor haplotype analyses support an association between genetic variation near NOTCH4 and bipolar disorder

Nested association between genetic variation in tryptophan hydroxylase II, bipolar affective disorder, and suicide attempts

scientific article published on 27 June 2006

Neurotransmission and bipolar disorder: a systematic family-based association study

scientific article published on October 2008

Novel genetic loci associated with hippocampal volume

scientific article published on 18 January 2017

Novel genetic loci underlying human intracranial volume identified through genome-wide association

scientific article (publication date: 3 October 2016)

Panic disorder with familial bipolar disorder

scientific article published on 01 July 1997

Parental diagnoses in youth with narrow phenotype bipolar disorder or severe mood dysregulation

scientific article published in August 2007

Pharmacogenetics of antidepressants, mood stabilizers, and antipsychotics in diverse human populations

scientific article published on September 2013

Pharmacogenetics of major depression: insights from level 1 of the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial

scientific article

Pharmacogenetics studies in STAR*D: strengths, limitations, and results

scientific article

Pharmacogenomics and personalized medicine in neuropsychiatry

scientific article

Pioneering first steps and cautious conclusions

scientific article published in January 2010

Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder

scientific article published on 24 August 2020

Prediction of treatment outcomes in psychiatry--where do we stand ?

scientific article

Quantitative analysis of leukocyte mitochondrial DNA deletion in affective disorders

article

RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder

scientific article published on 07 January 2014

Race, genetic ancestry and response to antidepressant treatment for major depression

scientific article published on 05 July 2013

Rapid mood switching and suicidality in familial bipolar disorder

scientific article published in October 2005

Rare variants in neuronal excitability genes influence risk for bipolar disorder

scientific article

Rediscovering the value of families for psychiatric genetics research

article

Reply to Asherson and Owen

scientific article published in February 1994

Reply to Petronis et al

Reply to “Replication of association of 3p21.1 with susceptibility to bipolar disorder but not major depression”

Response to Zhang et al. (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16.

scientific article

Retention and attrition among African Americans in the STAR*D study: what causes research volunteers to stay or stray?

scientific article published on 30 May 2013

Risk factors for suicide in bipolar I disorder in two prospectively studied cohorts

scientific article published on 13 October 2015

SERT Ileu425Val in autism, Asperger syndrome and obsessive-compulsive disorder

scientific article

SSRI response in depression may be influenced by SNPs in HTR1B and HTR1A.

scientific article published on December 2009

Sequence variation in DOCK9 and heterogeneity in bipolar disorder.

scientific article

Sodium valproate rescues expression of TRANK1 in iPSC-derived neural cells that carry a genetic variant associated with serious mental illness

scientific article published on 22 August 2018

Sodium valproate rescues expression of TRANK1 in iPSC-derived neural cells that carry a genetic variant associated with serious mental illness

Suggestive Linkage to Chromosomal Regions 13q31 and 22q12 in Families With Psychotic Bipolar Disorder

scientific article published on 01 April 2003

Suggestive evidence of a locus on chromosome 10p using the NIMH genetics initiative bipolar affective disorder pedigrees

article

Test-retest reliability of a new questionnaire for the retrospective assessment of long-term lithium use in bipolar disorder

scientific article

The Bcl-2 gene polymorphism rs956572AA increases inositol 1,4,5-trisphosphate receptor-mediated endoplasmic reticulum calcium release in subjects with bipolar disorder

scientific article

The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations

scientific article published on 04 May 2009

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

scientific article

The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort

scientific article published on 11 January 2008

The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatment

scientific article

The antidepressant efficacy of subanesthetic-dose ketamine does not correlate with baseline subcortical volumes in a replication sample with major depressive disorder.

scientific article

The bipolar disorder phenome database: a resource for genetic studies

scientific article (publication date: August 2007)

The genetic interacting landscape of 63 candidate genes in Major Depressive Disorder: an explorative study.

scientific article

The genetics of bipolar disorder

scientific article published on 06 January 2020

The genetics of panic disorder

article

The pharmacogenetics of major depression: past, present, and future

scientific article

Trapping and sequence analysis of 1138 putative exons from human chromosome 18

scientific article (publication date: June 2003)

Using duplicate genotyped data in genetic analyses: testing association and estimating error rates

scientific article

Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment

scientific article

What is familial about familial bipolar disorder? Resemblance among relatives across a broad spectrum of phenotypic characteristics

scientific article published in December 2006

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