List of works - Georgios Pollakis

A new class of free radical scavengers reducing adriamycin mitochondrial toxicity

article

Adriamycin and derivatives interaction with the mitochondrial membrane: O2 consumption and free radicals formation

scientific article published on 01 June 1984

Altered dynamics and differential infection profiles of lymphoid and myeloid cell subsets during acute and chronic HIV-1 infection

scientific article

Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.

scientific article

Association between gp120 envelope V1V2 and V4V5 variable loop profiles in a defined HIV-1 transmission cluster

scientific article

Bile salt-stimulated lipase from human milk binds DC-SIGN and inhibits human immunodeficiency virus type 1 transfer to CD4+ T cells

scientific article published in October 2006

Binding of human milk to pathogen receptor DC-SIGN varies with bile salt-stimulated lipase (BSSL) gene polymorphism

scientific article

Broad cross-clade T-cell responses to gag in individuals infected with human immunodeficiency virus type 1 non-B clades (A to G): importance of HLA anchor residue conservation

scientific article

CTL escape and increased viremia irrespective of HIV-specific CD4+ T-helper responses in two HIV-infected individuals

article

Characterization of an HIV-1 group M variant that is distinct from the known subtypes

scientific article published on March 2007

Colorectal mucus binds DC-SIGN and inhibits HIV-1 trans-infection of CD4+ T-lymphocytes

scientific article

Competition between inhibitors of the trypanosome alternative oxidase (TAO) and reduced coenzyme Q9.

scientific article

Damages of the mitochondrial membrane in adriamycin treated mice

scientific article published on 01 November 1984

Dendritic cell-induced activation of latent HIV-1 provirus in actively proliferating primary T lymphocytes

scientific article

Dendritic cells preferentially transfer CXCR4-using human immunodeficiency virus type 1 variants to CD4+ T lymphocytes in trans

scientific article published on 4 June 2008

Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020

scientific article published on 01 October 2020

Development of a nucleic acid sequence-based amplification assay that uses gag-based molecular beacons to distinguish between human immunodeficiency virus type 1 subtype C and C' infections in Ethiopia

scientific article published on April 2004

Differences in HIV Type 1 RNA Plasma Load Profile of Closely Related Cocirculating Ethiopian Subtype C Strains: C and C′

article

During Stably Suppressive Antiretroviral Therapy Integrated HIV-1 DNA Load in Peripheral Blood is Associated with the Frequency of CD8 Cells Expressing HLA-DR/DP/DQ

scientific article

Effect of chloroquine on reducing HIV-1 replication in vitro and the DC-SIGN mediated transfer of virus to CD4+ T-lymphocytes.

scientific article

Effects of helminths and Mycobacterium tuberculosis infection on HIV-1: a cellular immunological perspective

scientific article published on May 2012

Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4+ T lymphocytes

scientific article published on March 2007

Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence

article

Evidence of genetic variability of human immunodeficiency virus type 1 in plasma and cervicovaginal lavage in ethiopian women seeking care for sexually transmitted infections

scientific article

Generation of HIV-1 primary isolates representative of plasma variants using the U87.CD4 cell line

scientific article

Generation of representative primary virus isolates from blood plasma after isolation of HIV-1 with CD44 MicroBeads

scientific article

HIV RNA levels in transmission sources only weakly predict plasma viral load in recipients

article

HIV type 1 C and C' subclusters based on long terminal repeat sequences in the Ethiopian type 1 subtype C epidemic

scientific article published in October 2003

HIV type 1 mother-to-child transmission facilitated by distinctive glycosylation sites in the gp120 envelope glycoprotein

scientific article published on 24 October 2011

HIV-1 (co)receptors: implications for vaccine and therapy design

scientific article published on January 2010

HIV-1 autologous antibody neutralization associates with mother to child transmission

scientific article

HIV-1 disease progression is associated with bile-salt stimulated lipase (BSSL) gene polymorphism

article

HIV-1 disease progression is associated with bile-salt stimulated lipase (BSSL) gene polymorphism.

scientific article

HIV-1 subtype C in commercial sex workers in Addis Ababa, Ethiopia

scientific article published in February 2000

HIV-1 subtype C syncytium- and non-syncytium-inducing phenotypes and coreceptor usage among Ethiopian patients with AIDS

article

Human immunodeficiency virus type 1 gp120 envelope characteristics associated with disease progression differ in family members infected with genetically similar viruses

scientific article published on 26 September 2012

Human immunodeficiency virus type 1 subtypes have a distinct long terminal repeat that determines the replication rate in a host-cell-specific manner

scientific article published on April 2004

Identification of a genetic subcluster of HIV type 1 subtype C (C') widespread in Ethiopia

scientific article

Improved metastasis-free survival in nonadjuvantly treated postmenopausal breast cancer patients with chemokine receptor 5 del32 frameshift mutations

scientific article published on 20 May 2014

In vivo and in vitro modifications of the mitochondrial membrane induced by 4' Epi-adriamycin

scientific article published on 01 September 1986

Increased HIV-1 activity in anal high-grade squamous intraepithelial lesions compared with unaffected anal mucosa in men who have sex with men.

scientific article published on 5 March 2014

Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19

scholarly article by Ryan S Thwaites published in 2021

Innate immune factors associated with HIV-1 transmission

scientific article published on September 2011

Interaction of HIV-1 with dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-expressing cells is influenced by gp120 envelope modifications associated with disease progression

scientific article published on 28 September 2006

Intrapatient alterations in the human immunodeficiency virus type 1 gp120 V1V2 and V3 regions differentially modulate coreceptor usage, virus inhibition by CC/CXC chemokines, soluble CD4, and the b12 and 2G12 monoclonal antibodies

scientific article

Lack of in vivo compartmentalization among HIV-1 infected naïve and memory CD4+ T cell subsets

scientific article published on 20 August 2009

Latency profiles of full length HIV-1 molecular clone variants with a subtype specific promoter

scientific article published on 16 September 2011

Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T lymphocytes

scientific article

Mapping of SARS-CoV-2 IgM and IgG in gingival crevicular fluid: Antibody dynamics and linkage to severity of COVID-19 in hospital inpatients

scientific article published in 2022

Mitochondrial development in Trypanosoma brucei brucei transitional bloodstream forms

scientific article published in April 1991

Mitochondrial membrane modifications induced by adriamycin-mediated electron transport

scientific article published on 01 March 1983

Mucin 6 in seminal plasma binds DC-SIGN and potently blocks dendritic cell mediated transfer of HIV-1 to CD4(+) T-lymphocytes

scientific article

N-Linked Glycosylation of the HIV Type-1 gp120 Envelope Glycoprotein as a Major Determinant of CCR5 and CXCR4 Coreceptor Utilization

scientific article published in Journal of Biological Chemistry

Non-cytochrome mediated mitochondrial ATP production in bloodstream form Trypanosoma brucei brucei

article

Optimization of human immunodeficiency virus type 1 envelope glycoproteins with V1/V2 deleted, using virus evolution

scientific article published on 15 October 2008

Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease: An International Multicenter Study

scientific article published on 02 October 2020

P07-10. Natural compounds in bodily fluids which bind DC-SIGN and prevent HIV-1 capture and transfer to CD4 cells.

scientific article

Phenotypic and genotypic comparisons of CCR5- and CXCR4-tropic human immunodeficiency virus type 1 biological clones isolated from subtype C-infected individuals

scientific article published on March 2004

Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection

scientific article

Primary HIV-1 subtype C infection in Ethiopia

scientific article published in August 2002

Quantitation of HIV-1 DNA with a sensitive TaqMan assay that has broad subtype specificity

scientific article

RNA detection and subtype C assessment of HIV-1 in infants with diarrhea in Ethiopia

scientific article published on 20 May 2009

Rapid CD4+ T-lymphocyte depletion in rhesus monkeys infected with a simian-human immunodeficiency virus expressing the envelope glycoproteins of a primary dual-tropic Ethiopian Clade C HIV type 1 isolate

scientific article

Real-time, portable genome sequencing for Ebola surveillance

scientific article

Recombination of HIV type 1C (C'/C") in Ethiopia: possible link of EthHIV-1C' to subtype C sequences from the high-prevalence epidemics in India and Southern Africa

scientific article published on November 2003

Respiration of bloodstream forms of the parasite Trypanosoma brucei brucei is dependent on a plant-like alternative oxidase

scientific article

Role of the quinone structure in the mitochondrial damage induced by antitumor anthracyclines

scientific article published on 01 May 1983

Schistosoma mansoni soluble egg antigen (SEA) and recombinant Omega-1 modulate induced CD4+ T-lymphocyte responses and HIV-1 infection in vitro

scientific article published on 05 September 2019

Selective packaging of cellular miRNAs in HIV-1 particles

scientific article

Statins disrupt CCR5 and RANTES expression levels in CD4(+) T lymphocytes in vitro and preferentially decrease infection of R5 versus X4 HIV-1

scientific article

Surveillance technology for HIV-1 subtype C in Ethiopia: an env-based NASBA molecular beacon assay to discriminate between subcluster C and C'.

scientific article

Temporal and spatial analysis of the 2014-2015 Ebola virus outbreak in West Africa

scientific article published on 17 June 2015

Timing of the HIV-1 subtype C epidemic in Ethiopia based on early virus strains and subsequent virus diversification

scientific article published in August 2001

Timing of the Introduction into Ethiopia of Subcluster C′ of HIV Type 1 Subtype C

article

Transmission of two distinct HIV type 1 strains to an individual that were harbored for many years by another

scientific article published on 26 July 2011

Use of (alternative) coreceptors for HIV entry

scientific article published on September 2012

Use of dried spots of whole blood, plasma, and mother's milk collected on filter paper for measurement of human immunodeficiency virus type 1 burden

scientific article published on 24 January 2007

Varied sensitivity to therapy of HIV-1 strains in CD4+ lymphocyte sub-populations upon ART initiation

scientific article

Virus genomes reveal factors that spread and sustained the Ebola epidemic

scientific article (publication date: 12 April 2017)

List of works by Georgios Pollakis

A new class of free radical scavengers reducing adriamycin mitochondrial toxicity

Adriamycin and derivatives interaction with the mitochondrial membrane: O2 consumption and free radicals formation

Altered dynamics and differential infection profiles of lymphoid and myeloid cell subsets during acute and chronic HIV-1 infection

Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.

Association between gp120 envelope V1V2 and V4V5 variable loop profiles in a defined HIV-1 transmission cluster

Bile salt-stimulated lipase from human milk binds DC-SIGN and inhibits human immunodeficiency virus type 1 transfer to CD4+ T cells

Binding of human milk to pathogen receptor DC-SIGN varies with bile salt-stimulated lipase (BSSL) gene polymorphism

Broad cross-clade T-cell responses to gag in individuals infected with human immunodeficiency virus type 1 non-B clades (A to G): importance of HLA anchor residue conservation

CTL escape and increased viremia irrespective of HIV-specific CD4+ T-helper responses in two HIV-infected individuals

Characterization of an HIV-1 group M variant that is distinct from the known subtypes

Colorectal mucus binds DC-SIGN and inhibits HIV-1 trans-infection of CD4+ T-lymphocytes

Competition between inhibitors of the trypanosome alternative oxidase (TAO) and reduced coenzyme Q9.

Damages of the mitochondrial membrane in adriamycin treated mice

Dendritic cell-induced activation of latent HIV-1 provirus in actively proliferating primary T lymphocytes

Dendritic cells preferentially transfer CXCR4-using human immunodeficiency virus type 1 variants to CD4+ T lymphocytes in trans

Detection of neutralising antibodies to SARS-CoV-2 to determine population exposure in Scottish blood donors between March and May 2020

Development of a nucleic acid sequence-based amplification assay that uses gag-based molecular beacons to distinguish between human immunodeficiency virus type 1 subtype C and C' infections in Ethiopia

Differences in HIV Type 1 RNA Plasma Load Profile of Closely Related Cocirculating Ethiopian Subtype C Strains: C and C′

During Stably Suppressive Antiretroviral Therapy Integrated HIV-1 DNA Load in Peripheral Blood is Associated with the Frequency of CD8 Cells Expressing HLA-DR/DP/DQ

Effect of chloroquine on reducing HIV-1 replication in vitro and the DC-SIGN mediated transfer of virus to CD4+ T-lymphocytes.

Effects of helminths and Mycobacterium tuberculosis infection on HIV-1: a cellular immunological perspective

Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4+ T lymphocytes

Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence

Evidence of genetic variability of human immunodeficiency virus type 1 in plasma and cervicovaginal lavage in ethiopian women seeking care for sexually transmitted infections

Generation of HIV-1 primary isolates representative of plasma variants using the U87.CD4 cell line

Generation of representative primary virus isolates from blood plasma after isolation of HIV-1 with CD44 MicroBeads

HIV RNA levels in transmission sources only weakly predict plasma viral load in recipients

HIV type 1 C and C' subclusters based on long terminal repeat sequences in the Ethiopian type 1 subtype C epidemic

HIV type 1 mother-to-child transmission facilitated by distinctive glycosylation sites in the gp120 envelope glycoprotein

HIV-1 (co)receptors: implications for vaccine and therapy design

HIV-1 autologous antibody neutralization associates with mother to child transmission

HIV-1 disease progression is associated with bile-salt stimulated lipase (BSSL) gene polymorphism

HIV-1 disease progression is associated with bile-salt stimulated lipase (BSSL) gene polymorphism.

HIV-1 subtype C in commercial sex workers in Addis Ababa, Ethiopia

HIV-1 subtype C syncytium- and non-syncytium-inducing phenotypes and coreceptor usage among Ethiopian patients with AIDS

Human immunodeficiency virus type 1 gp120 envelope characteristics associated with disease progression differ in family members infected with genetically similar viruses

Human immunodeficiency virus type 1 subtypes have a distinct long terminal repeat that determines the replication rate in a host-cell-specific manner

Identification of a genetic subcluster of HIV type 1 subtype C (C') widespread in Ethiopia

Improved metastasis-free survival in nonadjuvantly treated postmenopausal breast cancer patients with chemokine receptor 5 del32 frameshift mutations

In vivo and in vitro modifications of the mitochondrial membrane induced by 4' Epi-adriamycin

Increased HIV-1 activity in anal high-grade squamous intraepithelial lesions compared with unaffected anal mucosa in men who have sex with men.

Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19

Innate immune factors associated with HIV-1 transmission

Interaction of HIV-1 with dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-expressing cells is influenced by gp120 envelope modifications associated with disease progression

Intrapatient alterations in the human immunodeficiency virus type 1 gp120 V1V2 and V3 regions differentially modulate coreceptor usage, virus inhibition by CC/CXC chemokines, soluble CD4, and the b12 and 2G12 monoclonal antibodies

Lack of in vivo compartmentalization among HIV-1 infected naïve and memory CD4+ T cell subsets

Latency profiles of full length HIV-1 molecular clone variants with a subtype specific promoter

Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4+ T lymphocytes

Mapping of SARS-CoV-2 IgM and IgG in gingival crevicular fluid: Antibody dynamics and linkage to severity of COVID-19 in hospital inpatients

Mitochondrial development in Trypanosoma brucei brucei transitional bloodstream forms

Mitochondrial membrane modifications induced by adriamycin-mediated electron transport

Mucin 6 in seminal plasma binds DC-SIGN and potently blocks dendritic cell mediated transfer of HIV-1 to CD4(+) T-lymphocytes

N-Linked Glycosylation of the HIV Type-1 gp120 Envelope Glycoprotein as a Major Determinant of CCR5 and CXCR4 Coreceptor Utilization

Non-cytochrome mediated mitochondrial ATP production in bloodstream form Trypanosoma brucei brucei

Optimization of human immunodeficiency virus type 1 envelope glycoproteins with V1/V2 deleted, using virus evolution

Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease: An International Multicenter Study

P07-10. Natural compounds in bodily fluids which bind DC-SIGN and prevent HIV-1 capture and transfer to CD4 cells.

Phenotypic and genotypic comparisons of CCR5- and CXCR4-tropic human immunodeficiency virus type 1 biological clones isolated from subtype C-infected individuals

Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection

Primary HIV-1 subtype C infection in Ethiopia

Quantitation of HIV-1 DNA with a sensitive TaqMan assay that has broad subtype specificity

RNA detection and subtype C assessment of HIV-1 in infants with diarrhea in Ethiopia

Rapid CD4+ T-lymphocyte depletion in rhesus monkeys infected with a simian-human immunodeficiency virus expressing the envelope glycoproteins of a primary dual-tropic Ethiopian Clade C HIV type 1 isolate

Real-time, portable genome sequencing for Ebola surveillance

Recombination of HIV type 1C (C'/C") in Ethiopia: possible link of EthHIV-1C' to subtype C sequences from the high-prevalence epidemics in India and Southern Africa

Respiration of bloodstream forms of the parasite Trypanosoma brucei brucei is dependent on a plant-like alternative oxidase

Role of the quinone structure in the mitochondrial damage induced by antitumor anthracyclines

Schistosoma mansoni soluble egg antigen (SEA) and recombinant Omega-1 modulate induced CD4+ T-lymphocyte responses and HIV-1 infection in vitro

Selective packaging of cellular miRNAs in HIV-1 particles

Statins disrupt CCR5 and RANTES expression levels in CD4(+) T lymphocytes in vitro and preferentially decrease infection of R5 versus X4 HIV-1

Surveillance technology for HIV-1 subtype C in Ethiopia: an env-based NASBA molecular beacon assay to discriminate between subcluster C and C'.

Temporal and spatial analysis of the 2014-2015 Ebola virus outbreak in West Africa

Timing of the HIV-1 subtype C epidemic in Ethiopia based on early virus strains and subsequent virus diversification

Timing of the Introduction into Ethiopia of Subcluster C′ of HIV Type 1 Subtype C

Transmission of two distinct HIV type 1 strains to an individual that were harbored for many years by another

Use of (alternative) coreceptors for HIV entry

Use of dried spots of whole blood, plasma, and mother's milk collected on filter paper for measurement of human immunodeficiency virus type 1 burden

Varied sensitivity to therapy of HIV-1 strains in CD4+ lymphocyte sub-populations upon ART initiation

Virus genomes reveal factors that spread and sustained the Ebola epidemic