List of works by Stephan von Hörsten

A Mutation in Aminopeptidase N (CD13) Isolated from a Patient Suffering from Leukemia Leads to an Arrest in the Endoplasmic Reticulum

scientific article published in Journal of Biological Chemistry

A Sphingosine-1-Phosphate Receptor Modulator Attenuated Secondary Brain Injury and Improved Neurological Functions of Mice after ICH

scientific article published on 04 September 2020

A dopaminergic mechanism of antipsychotic drug efficacy, failure, and failure reversal: the role of the dopamine transporter

scientific article published on 23 July 2018

A role for neuropeptide Y (NPY) in phagocytosis: implications for innate and adaptive immunity

scientific article published on 19 January 2007

Age-dependent development of the splenic marginal zone in human infants is associated with different causes of death

scientific article published in January 2004

Age-dependent gene expression profile and protein expression in a transgenic rat model of Huntington's disease

scientific article published on 22 October 2008

Age-related effect of peptide YY (PYY) on paw edema in the rat: The function of Y1 receptors on inflammatory cells

scientific article published on 30 June 2006

Airway-specific recruitment of T cells is reduced in a CD26-deficient F344 rat substrain

scientific article published on 01 October 2009

Altered diffusion tensor imaging measurements in aged transgenic Huntington disease rats

scientific article published on 23 May 2012

Altered emotional and motivational processing in the transgenic rat model for Huntington's disease.

scientific article published on 25 November 2010

Altered hypothalamic protein expression in a rat model of Huntington's disease

scientific article

Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro

scientific article published on 29 January 2020

Assessing the potential clinical utility of transplantations of neural and mesenchymal stem cells for treating neurodegenerative diseases

scientific article published in January 2012

Automated behavioral phenotyping reveals presymptomatic alterations in a SCA3 genetrap mouse model

scientific article published on 15 May 2012

Automated phenotyping and advanced data mining exemplified in rats transgenic for Huntington's disease

scientific article

Behavioral abnormalities precede neuropathological markers in rats transgenic for Huntington's disease.

scientific article published on 19 September 2006

Behavioral and in vivo electrophysiological evidence for presymptomatic alteration of prefrontostriatal processing in the transgenic rat model for huntington disease

scientific article

Behavioral effects of neuropeptide Y in F344 rat substrains with a reduced dipeptidyl-peptidase IV activity

scientific article published in July 2003

Behavioral phenotyping of mice in pharmacological and toxicological research

scientific article

Behaviorally conditioned immunosuppression using cyclosporine A: central nervous system reduces IL-2 production via splenic innervation

scientific article

Brain NPY Y1 receptors rapidly mediate the behavioral response to novelty and a compartment-specific modulation of granulocyte function in blood and spleen

scientific article published in September 1998

CD26 expression determines lung metastasis in mutant F344 rats: involvement of NK cell function and soluble CD26.

scientific article published on September 2003

CD26/dipeptidyl peptidase 4-deficiency alters thymic emigration patterns and leukcocyte subsets in F344-rats age-dependently.

scientific article published in December 2008

Capturing schizophrenia-like prodromal symptoms in a spinocerebellar ataxia-17 transgenic rat.

scientific article published on 8 November 2016

Cellular and subcellular localization of Huntingtin [corrected] aggregates in the brain of a rat transgenic for Huntington disease

scientific article

Central NPY receptor-mediated alteration of heart rate dynamics in mice during expression of fear conditioned to an auditory cue.

scientific article

Centrally applied NPY mimics immunoactivation induced by non-analgesic doses of met-enkephalin

scientific article published on 01 December 1998

Conditioned taste aversion produced by cyclosporine A: concomitant reduction in lymphoid organ weight and splenocyte proliferation

scientific article published in January 1998

Correction: Altered Hypothalamic Protein Expression in a Rat Model of Huntington's Disease

Cut to the chase: a review of CD26/dipeptidyl peptidase-4's (DPP4) entanglement in the immune system

scientific article published on 25 February 2016

Cyclosporine A affects open field behavior in DA rats

scientific article

DPP4 inhibitors increase differentially the expression of surfactant proteins in Fischer 344 rats.

scientific article published on 15 September 2014

DPP4-deficient congenic rats display blunted stress, improved fear extinction and increased central NPY.

scientific article

Differential OVA-induced pulmonary inflammation and unspecific reaction in Dark Agouti (DA) rats contingent on CD26/DPPIV deficiency

scientific article published on 22 July 2014

Differential effects of neuropeptide Y (NPY) on leukocyte subsets in the blood: mobilization of B-1-like B-lymphocytes and activated monocytes

scientific article published on 01 July 2001

Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies

scientific article published on 29 July 2016

Dipeptidyl peptidase IV (DPP4) deficiency increases Th1-driven allergic contact dermatitis

scientific article published on 14 June 2011

Dipeptidyl peptidase IV (DPP4)-deficiency attenuates diet-induced obesity in rats: Possible implications for the hypothalamic neuropeptidergic system

scientific article published on September 29, 2010

Dipeptidyl peptidase expression during experimental colitis in mice

scientific article published on 01 August 2010

Dipeptidylpeptidase 4 as a Marker of Activated Fibroblasts and a Potential Target for the Treatment of Fibrosis in Systemic Sclerosis

scientific article published on 01 January 2020

Disrupted-in-Schizophrenia 1 (DISC1) Overexpression and Juvenile Immune Activation Cause Sex-Specific Schizophrenia-Related Psychopathology in Rats

Dose-dependent recruitment of CD25+ and CD26+ T cells in a novel F344 rat model of asthma

scientific article published on 09 March 2007

Dynamic footprint based locomotion sway assessment in α-synucleinopathic mice using Fast Fourier Transform and Low Pass Filter

scientific article published on 15 December 2017

Dynamic footprints of α-synucleinopathic mice recorded by CatWalk gait analysis.

scientific article published on 3 January 2018

Dysregulation of coordinated neuronal firing patterns in striatum of freely behaving transgenic rats that model Huntington's disease

scientific article published on 08 October 2009

Early Alterations in Operant Performance and Prominent Huntingtin Aggregation in a Congenic F344 Rat Line of the Classical CAGn51trunc Model of Huntington Disease

scientific article published on 25 January 2018

Early cognitive dysfunction in the HD 51 CAG transgenic rat model of Huntington's disease

scientific article published in June 2012

Early deficits in declarative and procedural memory dependent behavioral function in a transgenic rat model of Huntington's disease.

scientific article published on 5 November 2012

Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition

article published in the Proceedings of the National Academy of Sciences of the United States of America

Early postnatal hyperalimentation impairs renal function via SOCS-3 mediated renal postreceptor leptin resistance.

scientific article

Effect of early experience on behavior and immune response in the rat.

scientific article

Effect of neuropeptide Y on inflammatory paw edema in the rat: involvement of peripheral NPY Y1 and Y5 receptors and interaction with dipeptidyl-peptidase IV (CD26)

scientific journal article

Effects of dipeptidyl peptidase-4 inhibition in an animal model of experimental asthma: a matter of dose, route, and time

scientific article published on 2 October 2013

Effects of in-utero environment and maternal behaviour on neuroendocrine and behavioural alterations in a mouse model of prenatal trauma

scientific article

Endogenous mouse huntingtin is highly abundant in cranial nerve nuclei, co-aggregates to Abeta plaques and is induced in reactive astrocytes in a transgenic mouse model of Alzheimer's disease

Enhanced Y1-receptor-mediated vasoconstrictive action of neuropeptide Y (NPY) in superior mesenteric arteries in portal hypertension

scientific article published on 23 September 2005

Enhanced susceptibility to periodontitis in an animal model of depression: reversed by chronic treatment with the anti-depressant tianeptine

scientific article published in July 2006

Experimental allergic encephalomyelitis in adult DA rats subjected to neonatal handling or gentling.

scientific article published in April 1995

Extreme reduction of dipeptidyl peptidase IV activity in F344 rat substrains is associated with various behavioral differences

scientific article published in October 2003

FDG μPET Fails to Detect a Disease-Specific Phenotype in Rats Transgenic for Huntington's Disease – A 15 Months Follow-up Study

scientific article published in January 2015

Factors influencing behavior of group-housed male rats in the social interaction test: focus on cohort removal.

scientific article published in October 2001

From Kratom to mitragynine and its derivatives: physiological and behavioural effects related to use, abuse, and addiction

scientific article

Generalization of contextual fear depends on associative rather than non-associative memory components

scientific article published on 30 May 2012

Genotype specific age related changes in a transgenic rat model of Huntington's disease

scientific article

Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug development

scientific article

Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration

scientific article

Guidelines for preclinical animal research in ALS/MND: A consensus meeting

scientific article published on January 2010

Identification and characterization of Huntington related pathology: an in vivo DKI imaging study

scientific article published on 25 June 2012

Identifying neuropeptide Y (NPY) as the main stress-related substrate of dipeptidyl peptidase 4 (DPP4) in blood circulation.

scientific article published on 27 February 2016

Impaired Decision Making and Loss of Inhibitory-Control in a Rat Model of Huntington Disease

scientific article published on 26 October 2016

Impaired regulation of brain mitochondria by extramitochondrial Ca2+ in transgenic Huntington disease rats

scientific article published on 07 July 2008

In situ enzymatic activity of transglutaminase isoforms on brain tissue sections of rodents: A new approach to monitor differences in post-translational protein modifications during neurodegeneration.

scientific article published on 23 November 2015

In vivo monitoring of natural killer cell-dependent clearance of lung metastasis using dynamic positron emission tomography.

scientific article

Increased numbers of motor activity peaks during light cycle are associated with reductions in adrenergic alpha(2)-receptor levels in a transgenic Huntington's disease rat model.

scientific article published on 30 June 2009

Inhibition of CD26/dipeptidyl peptidase IV enhances CCL11/eotaxin-mediated recruitment of eosinophils in vivo.

scientific article published in July 2008

Inhibition of glutaminyl cyclase prevents pGlu-Abeta formation after intracortical/hippocampal microinjection in vivo/in situ.

scientific article

Intratracheal macrophage-activating lipopeptide-2 reduces metastasis in the rat lung

scientific article published on March 2003

IsoQC (QPCTL) knock-out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes.

scientific article published on 20 August 2015

Kinetics of the early recruitment of leukocyte subsets at the sites of tumor cells in the lungs: natural killer (NK) cells rapidly attract monocytes but not lymphocytes in the surveillance of micrometastasis

scientific article

Localization, transmission, spontaneous mutations, and variation of function of the Dpp4 (Dipeptidyl-peptidase IV; CD26) gene in rats

scientific article published in September 2003

Maternal deprivation decelerates postnatal morphological lung development of F344 rats.

scientific article

Memory deficits in the transgenic rat model of Huntington's disease

scientific article

Metabolic and electrophysiological changes in the basal ganglia of transgenic Huntington's disease rats

scientific article published on 17 July 2012

Microstructural changes observed with DKI in a transgenic Huntington rat model: evidence for abnormal neurodevelopment

scientific article

Modified impact of emotion on temporal discrimination in a transgenic rat model of Huntington disease

scientific article published on 26 September 2013

Modulation of innate immune functions by intracerebroventricularly applied neuropeptide Y: dose and time dependent effects

scientific article published on 01 January 1998

Molecular crosstalk between Y5 receptor and neuropeptide Y drives liver cancer

scientific article published on 13 April 2020

More sympathy for autoimmunity with neuropeptide Y?

scientific article published in October 2004

Motor and cognitive improvement by deep brain stimulation in a transgenic rat model of Huntington's disease

scientific article published on 14 August 2006

Motor function and dopamine release measurements in transgenic Huntington's disease model rats

scientific article published on 24 February 2012

Myofibrillar instability exacerbated by acute exercise in filaminopathy.

scientific article published on 15 October 2015

NPY modulates epinephrine-induced leukocytosis via Y-1 and Y-5 receptor activation in vivo: sympathetic co-transmission during leukocyte mobilization

scientific article published in November 2002

Neonatal sound stress and development of experimental allergic encephalomyelitis in Lewis and DA rats

scientific article

Neurobehavioral tests in rat models of degenerative brain diseases

scientific article published in January 2010

Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease.

scientific article published in March 2008

Neuropeptide Y (NPY) cleaving enzymes: structural and functional homologues of dipeptidyl peptidase 4.

scientific article

Neuropeptide Y (NPY) in cerebrospinal fluid from patients with Huntington's Disease: increased NPY levels and differential degradation of the NPY1-30 fragment

scientific article

Neuropeptide Y (NPY) modulates oxidative burst and nitric oxide production in carrageenan-elicited granulocytes from rat air pouch

scientific article published on 28 September 2006

Neuropeptide Y (NPY) suppresses experimental autoimmune encephalomyelitis: NPY1 receptor-specific inhibition of autoreactive Th1 responses in vivo.

scientific article published in October 2003

Neuropeptide Y Cotransmission with Norepinephrine in the Sympathetic Nerve-Macrophage Interplay

scientific article published on 01 December 2000

Neuropeptide Y Y1 receptor-mediated anxiolysis in the dorsocaudal lateral septum: functional antagonism of corticotropin-releasing hormone-induced anxiety.

scientific article published in January 2001

Neuropeptide Y and its receptor subtypes specifically modulate rat peritoneal macrophage functions in vitro: counter regulation through Y1 and Y2/5 receptors

scientific article published on 01 January 2005

Neuropeptide Y receptor-specifically modulates human neutrophil function.

scientific article

Neuropeptide Y stabilizes body temperature and prevents hypotension in endotoxaemic rats.

scientific article

Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis

scientific article published on 01 February 2009

Nicotinic acetylcholine receptor activation mediates nicotine-induced enhancement of experimental periodontitis.

scientific article

Normal sensitivity to excitotoxicity in a transgenic Huntington's disease rat.

scientific article published on 20 January 2006

Novel role of NPY in neuroimmune interaction and lung growth after intrauterine growth restriction.

scientific article published in June 2017

Olfactory neuron-specific expression of A30P α-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages

scientific article

Opioid receptor-mediated suppression of humoral immune response in vivo and in vitro: involvement of kappa opioid receptors.

scientific article

Peritoneal exudate cells from long-lived rats exhibit increased IL-10/IL-1β expression ratio and preserved NO/urea ratio following LPS-stimulation in vitro

scientific article

Persistent changes within the intrinsic kidney-associated NPY system and tubular function by litter size reduction.

scientific article published on 2 March 2011

Phenotyping of congenic dipeptidyl peptidase 4 (DP4) deficient Dark Agouti (DA) rats suggests involvement of DP4 in neuro-, endocrine, and immune functions

scientific article

Postnatal experiences influence the behavior in adult male and female Fischer and Lewis rats

scientific article

Postnatal life events affect the severity of asthmatic airway inflammation in the adult rat.

scientific article

Postnatal lipopolysaccharide-induced illness predisposes to periodontal disease in adulthood

scientific article published in August 2002

Postnatal maternal deprivation aggravates experimental autoimmune encephalomyelitis in adult Lewis rats: reversal by chronic imipramine treatment

scientific article published in April 2002

Postnatal morphological lung development of wild type and CD26/DPP4 deficient rat pups in dependency of LPS exposure

scientific article published on 22 October 2019

Postnatally induced differences in adult pain sensitivity depend on genetics, gender and specific experiences: reversal of maternal deprivation effects by additional postnatal tactile stimulation or chronic imipramine treatment

scientific article published in July 2002

Progressive deterioration of reaction time performance and choreiform symptoms in a new Huntington's disease transgenic ratmodel

scientific article published on 29 March 2006

Proteolytic degradation of neuropeptide Y (NPY) from head to toe: Identification of novel NPY-cleaving peptidases and potential drug interactions in CNS and Periphery.

scientific article published on 7 October 2015

Reduced airway inflammation in CD26/DPP4-deficient F344 rats is associated with altered recruitment patterns of regulatory T cells and expression of pulmonary surfactant proteins

scientific article published on 01 December 2010

Reduced tissue immigration of monocytes by neuropeptide Y during endotoxemia is associated with Y2 receptor activation

scientific journal article

Reduction in subventricular zone-derived olfactory bulb neurogenesis in a rat model of Huntington's disease is accompanied by striatal invasion of neuroblasts

scientific article

Regional and subtype selective changes of neurotransmitter receptor density in a rat transgenic for the Huntington's disease mutation

scientific article published in August 2005

Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats.

scientific article published on 29 October 2007

Relevance of neuropeptide Y for the neuroimmune crosstalk.

scientific article

Role of hypothalamus-pituitary-adrenal axis modulation in the stress-resilient phenotype of DPP4-deficient rats

scientific article published on 31 August 2018

Selective hippocampal neurodegeneration in transgenic mice expressing small amounts of truncated Aβ is induced by pyroglutamate-Aβ formation.

scientific article published in September 2011

Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats

scientific article published on 9 February 2006

Serum levels of a subset of cytokines show high interindividual variability and are not altered in rats transgenic for Huntington´s disease

scientific article

Sex differences in a transgenic rat model of Huntington's disease: decreased 17beta-estradiol levels correlate with reduced numbers of DARPP32+ neurons in males

scientific article published on 23 May 2008

Silhouette-Length-Scaled Gait Parameters for Motor Functional Analysis in Mice and Rats

scientific article published on 01 November 2019

Soluble DPP4 originates in part from bone marrow cells and not from the kidney.

scientific article

Spontaneous in vitro transformation of adult neural precursors into stem-like cancer cells.

scientific article published on 10 July 2008

Stem cell quiescence in the hippocampal neurogenic niche is associated with elevated transforming growth factor-beta signaling in an animal model of Huntington disease

scientific article published on July 2010

Stereological quantification of carboxyfluorescein-labeled rat lung metastasis: a new method for the assessment of natural killer cell activity and tumor adhesion in vivo and in situ

scientific article

Stress-induced hyperthermia in the rat: comparison of classical and novel recording methods

scientific article published on 01 April 2006

Strumpellin is a novel valosin-containing protein binding partner linking hereditary spastic paraplegia to protein aggregation diseases.

scientific article published on 9 September 2010

Subtle but progressive cognitive deficits in the female tgHD hemizygote rat as demonstrated by operant SILT performance.

scientific article

Suppression of experimental autoimmune encephalomyelitis by ghrelin

scientific article

Synthetic retinoid AM80 inhibits Th17 cells and ameliorates experimental autoimmune encephalomyelitis

scientific article published on 23 April 2009

Systematic data analysis and data mining in CatWalk gait analysis by heat mapping exemplified in rodent models for neurodegenerative diseases

scientific article published on 24 July 2019

Temporal sensitivity changes with extended training in a bisection task in a transgenic rat model

scientific article published on 28 September 2011

The neurocircuitry and receptor subtypes mediating anxiolytic-like effects of neuropeptide Y.

scientific article

Transferred T cells preferentially adhere in the BALT of CD26-deficient recipient lungs during asthma

scientific article published on 07 June 2009

Transgenic Rat Models of Huntington's Disease

scientific article published on January 2015

Transgenic rat model of Huntington's disease

scientific article published in March 2003

Transglutaminase 6 Is Colocalized and Interacts with Mutant Huntingtin in Huntington Disease Rodent Animal Models

scholarly article

Unravelling the immunological roles of dipeptidyl peptidase 4 (DPP4) activity and/or structure homologue (DASH) proteins

scientific article published on 16 December 2015

Up-regulation of platelet-derived growth factor by peripheral-blood leukocytes during experimental allergic encephalomyelitis

scientific article published on 01 February 2008

Use of cryostat sections from snap-frozen nervous tissue for combining stereological estimates with histological, cellular, or molecular analyses on adjacent sections

article

Y1 receptors regulate aggressive behavior by modulating serotonin pathways

scholarly article