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List of works by James Birchall

An anisotropic, hyperelastic model for skin: experimental measurements, finite element modelling and identification of parameters for human and murine skin

scientific article published on 19 November 2012

Changes in human Langerhans cells following intradermal injection of influenza virus-like particle vaccines

scientific article

Chitosan-modified dry powder formulations for pulmonary gene delivery

scientific article published on 2 May 2006

Clinical administration of microneedles: skin puncture, pain and sensation.

scientific article published in February 2009

Cutaneous DNA delivery and gene expression in ex vivo human skin explants via wet-etch micro-fabricated micro-needles

scientific article published in August 2005

Cutaneous gene expression of plasmid DNA in excised human skin following delivery via microchannels created by radio frequency ablation

scientific article published on 15 February 2006

Development of an ex vivo human skin model for intradermal vaccination: tissue viability and Langerhans cell behaviour.

scientific article published on 11 August 2009

Dynamic visualization of dendritic cell-antigen interactions in the skin following transcutaneous immunization

scientific article

Enhanced dispersibility and deposition of spray-dried powders for pulmonary gene therapy

scientific article published on August 2003

Examination of the biophysical interaction between plasmid DNA and the polycations, polylysine and polyornithine, as a basis for their differential gene transfection in-vitro.

scientific article published in December 2000

Gene delivery to the epidermal cells of human skin explants using microfabricated microneedles and hydrogel formulations

scientific article published on 2 August 2007

Gene expression in an intact ex-vivo skin tissue model following percutaneous delivery of cationic liposome-plasmid DNA complexes

scientific article published in March 2000

Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept

scientific article published on 8 January 2013

Host responses in human skin after conventional intradermal injection or microneedle administration of virus-like-particle influenza vaccine

scientific article

In vitro reporter gene transfection via plasmid DNA delivered by metered dose inhaler

scientific article

In vivo, in situ imaging of microneedle insertion into the skin of human volunteers using optical coherence tomography

scientific article published on 13 May 2010

Influenza virus-like particles coated onto microneedles can elicit stimulatory effects on Langerhans cells in human skin.

scientific article

Inhaled extended-release microparticles of heparin elicit improved pulmonary pharmacodynamics against antigen-mediated airway hyper-reactivity and inflammation

scientific article published on 16 July 2012

Low temperature fabrication of biodegradable sugar glass microneedles for transdermal drug delivery applications

scientific article published on 29 October 2011

Microfabricated silicon microneedles for nonviral cutaneous gene delivery

scientific article published in May 2004

Microneedle array technology: the time is right but is the science ready?

scientific article published on 01 January 2006

Microneedle delivery of H5N1 influenza virus-like particles to the skin induces long-lasting B- and T-cell responses in mice

scientific article

Microneedle mediated delivery of nanoparticles into human skin.

scientific article published on 4 September 2008

Microneedles in clinical practice--an exploratory study into the opinions of healthcare professionals and the public

scientific article published on 18 March 2010

Nuclear localisation and pDNA condensation in non-viral gene delivery

scientific article published on April 2007

Physical stability and in-vitro gene expression efficiency of nebulised lipid-peptide-DNA complexes

scientific article published in March 2000

Physico-chemical characterisation and transfection efficiency of lipid-based gene delivery complexes

scientific article published on June 1999

Preparation of dry powder dispersions for non-viral gene delivery by freeze-drying and spray-drying.

scientific article

Pulmonary delivery of nucleic acids

scientific article published in November 2007

Quantifying the mechanical properties of human skin to optimise future microneedle device design.

scientific article published on 12 July 2011

The development of a sensitive methodology to characterise hard shell capsule puncture by dry powder inhaler pins

scientific article published on 18 August 2013

The use of absorption enhancers to enhance the dispersibility of spray-dried powders for pulmonary gene therapy.

scientific article

Transcutaneous immunization using microneedles and cubosomes: Mechanistic investigations using Optical Coherence Tomography and Two-Photon Microscopy

scientific article published on 23 August 2013

Visualization of plasmid delivery to keratinocytes in mouse and human epidermis

scientific article published on 15 November 2011