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List of works by Shilpa Buch

A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection

scientific article published on October 2009

A growth factor attenuates HIV-1 Tat and morphine induced damage to human neurons: implication in HIV/AIDS-drug abuse cases

scientific article

Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers.

scientific article published on 27 October 2017

Accelerated evolution of SIV env within the cerebral compartment in the setting of morphine-dependent rapid disease progression

scientific article

Activation of Notch signaling pathway in HIV-associated nephropathy.

scientific article

Active simian immunodeficiency virus (strain smmPGm) infection in macaque central nervous system correlates with neurologic disease

scientific article published in April 2005

Analysis of the V1V2 region of the SIV envelope in the brains of morphine-dependent and control SIV/SHIV-infected macaques

scientific article

Angiotensin II increased neuronal stem cell proliferation: role of AT2R.

scientific article

Association of platelet-derived growth factor-B chain with simian human immunodeficiency virus encephalitis

scientific article

Astrocyte EV-Induced lincRNA-Cox2 Regulates Microglial Phagocytosis: Implications for Morphine-Mediated Neurodegeneration

scholarly article by Guoku Hu et al published 29 September 2018 in Molecular therapy. Nucleic acids

Bleomycin treatment causes enhancement of virus replication in the lungs of SHIV-infected macaques

scientific article published on 12 January 2007

CXCL10-induced cell death in neurons: role of calcium dysregulation

scientific article published in February 2006

CaMKIIalpha interacts with M4 muscarinic receptors to control receptor and psychomotor function

scientific journal article

Cannabinoid receptor 2 activation: a means to prevent monocyte-endothelium engagement

scientific article

Cationic surface modification of PLG nanoparticles offers sustained gene delivery to pulmonary epithelial cells

scientific article published on May 2010

Cellular Interactions and Signaling in neuroAIDS: Emerging Issues Colloquium

scientific article

Chronic SIV and morphine treatment increases heat shock protein 5 expression at the synapse

scientific article published on 3 June 2015

Chronic morphine exposure causes pronounced virus replication in cerebral compartment and accelerated onset of AIDS in SIV/SHIV-infected Indian rhesus macaques

scientific article published on 28 July 2006

Circulating Factors That Modify Lung Cell DNA Synthesis Following Exposure to Inhaled Oxidants. III. Effect of Plasma on Lung Pneumocyte and Fibroblast DNA Synthesis Following Exposure of Adult Rats to 85% Oxygen

scientific article published on 01 September 1991

Cocaine Exposure Results in Formation of Dendritic Varicosity in Rat Primary Hippocampal Neurons

scientific article published on January 2009

Cocaine Mediated Neuroinflammation: Role of Dysregulated Autophagy in Pericytes

scientific article published on 27 August 2018

Cocaine and HIV-1 interplay in CNS: cellular and molecular mechanisms

scientific article published on July 2012

Cocaine and HIV-1 interplay: molecular mechanisms of action and addiction

scientific article published on 16 July 2011

Cocaine and human immunodeficiency virus type 1 gp120 mediate neurotoxicity through overlapping signaling pathways

scientific article

Cocaine hijacks σ1 receptor to initiate induction of activated leukocyte cell adhesion molecule: implication for increased monocyte adhesion and migration in the CNS.

scientific article

Cocaine induces astrocytosis through ER stress-mediated activation of autophagy

scientific article published on 23 June 2016

Cocaine potentiates astrocyte toxicity mediated by human immunodeficiency virus (HIV-1) protein gp120

scientific article

Cocaine-Mediated Downregulation of miR-124 Activates Microglia by Targeting KLF4 and TLR4 Signaling.

scientific article

Cocaine-induced release of CXCL10 from pericytes regulates monocyte transmigration into the CNS

scientific article published on 09 January 2019

Cocaine-mediated alteration in tight junction protein expression and modulation of CCL2/CCR2 axis across the blood-brain barrier: implications for HIV-dementia

scientific article published on 29 November 2007

Cocaine-mediated downregulation of microglial miR-124 expression involves promoter DNA methylation.

scientific article published on 27 October 2016

Cocaine-mediated enhancement of virus replication in macrophages: implications for human immunodeficiency virus-associated dementia

scientific article published on December 2007

Cocaine-mediated induction of microglial activation involves the ER stress-TLR2 axis

scientific article published on 9 February 2016

Cocaine-mediated induction of platelet-derived growth factor: implication for increased vascular permeability

scientific journal article

Cocaine-mediated microglial activation involves the ER stress-autophagy axis.

scientific article

Cooperative induction of CXCL10 involves NADPH oxidase: Implications for HIV dementia.

scientific article

Deferoxamine mimics the pattern of hypoxia-related injury at the microvasculature

scientific article published in May 2009

Development of virus-specific immune responses in SHIV(KU)-infected macaques treated with PMPA.

scientific article

Differential regulation of platelet-derived growth factor genes in fetal rat lung fibroblasts

scientific article published in March 1994

Effect of cocaine on human immunodeficiency virus-mediated pulmonary endothelial and smooth muscle dysfunction

scientific article

Effect of morphine and SIV on dendritic cell trafficking into the central nervous system of rhesus macaques

scientific article published on 14 August 2013

Effects of Morphine on Behavioral Task Performance in SIV-Infected Rhesus Macaques

scientific article published on 2 April 2016

Emerging roles of extracellular vesicles in neurodegenerative disorders: focus on HIV-associated neurological complications

scientific article

Engineered Extracellular Vesicles Loaded With miR-124 Attenuate Cocaine-Mediated Activation of Microglia

scientific article published on 30 July 2020

Epigenetic Promoter DNA Methylation of miR-124 Promotes HIV-1 Tat-Mediated Microglial Activation via MECP2-STAT3 Axis

article

Exosomal miR-9 Released from HIV Tat Stimulated Astrocytes Mediates Microglial Migration

scientific article published in March 2018

Exosome-mediated shuttling of microRNA-29 regulates HIV Tat and morphine-mediated neuronal dysfunction.

scientific article

Growth factor signaling: implications for disease & therapeutics.

scientific article

HIV Tat 101-mediated loss of pericytes at the blood-brain barrier involves PDGF-BB

scientific article published on January 2015

HIV Tat induces expression of ICAM-1 in HUVECs: implications for miR-221/-222 in HIV-associated cardiomyopathy

scientific article

HIV Tat-Mediated Induction of Human Brain Microvascular Endothelial Cell Apoptosis Involves Endoplasmic Reticulum Stress and Mitochondrial Dysfunction.

scientific article published on 20 November 2014

HIV Tat-mediated induction of autophagy regulates the disruption of ZO-1 in brain endothelial cells

scientific article published on 16 April 2020

HIV gp120 induces mucus formation in human bronchial epithelial cells through CXCR4/α7-nicotinic acetylcholine receptors

scientific article

HIV neuropathogenesis: a tight rope walk of innate immunity.

scientific article

HIV-1 TAT-mediated microglial activation: role of mitochondrial dysfunction and defective mitophagy

article

HIV-1 Tat Primes and Activates Microglial NLRP3 Inflammasome-Mediated Neuroinflammation.

scientific article published on 07 March 2017

HIV-1 Tat co-operates with IFN-gamma and TNF-alpha to increase CXCL10 in human astrocytes

scientific article

HIV-1 Tat disrupts CX3CL1-CX3CR1 axis in microglia via the NF-κBYY1 pathway

scientific article published on January 2014

HIV-1 Tat-Induced Astrocytic Extracellular Vesicle miR-7 Impairs Synaptic Architecture

scientific article published on 10 August 2019

HIV-1 Tat-mediated astrocytic amyloidosis involves the HIF-1α/lncRNA BACE1-AS axis

scientific article published on 26 May 2020

HIV-1 Tat-mediated induction of platelet-derived growth factor in astrocytes: role of early growth response gene 1

scientific article

HIV-1 Tat-mediated neurotoxicity in retinal cells.

scientific article published on 28 January 2011

HIV-1 envelope protein gp120 up regulates CCL5 production in astrocytes which can be circumvented by inhibitors of NF-κB pathway

scientific article

HIV-1 gp120 induces expression of IL-6 through a nuclear factor-kappa B-dependent mechanism: suppression by gp120 specific small interfering RNA

scientific article

HIV-1 neuroimmunity in the era of antiretroviral therapy.

scientific article

HIV-1 transgenic rats display mitochondrial abnormalities consistent with abnormal energy generation and distribution

scientific article published on 3 February 2016

Hypoxia-inducible factor-1 α/platelet derived growth factor axis in HIV-associated pulmonary vascular remodeling

scientific article

IL-17A induces MIP-1α expression in primary astrocytes via Src/MAPK/PI3K/NF-kB pathways: implications for multiple sclerosis.

scientific article

Immunization of macaques with live simian human immunodeficiency virus (SHIV) vaccines conferred protection against AIDS induced by homologous and heterologous SHIVs and simian immunodeficiency virus

scientific article

Immunoprophylaxis against AIDS in macaques with a lentiviral DNA vaccine

scientific article published on 2 May 2006

Inhibition of pathogenic SHIV replication in macaques treated with antisense DNA of interleukin-4.

scientific article published on 23 December 2004

Inhibitory and enhancing effects of IFN-gamma and IL-4 on SHIV(KU) replication in rhesus macaque macrophages: correlation between Th2 cytokines and productive infection in tissue macrophages during late-stage infection

scientific article

Innate differences between simian-human immunodeficiency virus (SHIV)(KU-2)-infected rhesus and pig-tailed macaques in development of neurological disease

scientific article published on March 2002

Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders

scientific article published on February 2016

Investigations on four host response factors whose expression is enhanced in X4 SHIV encephalitis.

scientific article

Involvement of TRPC channels in CCL2-mediated neuroprotection against tat toxicity

scientific article published on February 2009

Involvement of miR-9/MCPIP1 axis in PDGF-BB-mediated neurogenesis in neuronal progenitor cells.

scientific article published on 12 December 2013

Involvement of sigma-1 receptor in astrocyte activation induced by methamphetamine via up-regulation of its own expression

scientific article

Lasting effects of transient postinoculation tenofovir [9-R-(2-Phosphonomethoxypropyl)adenine] treatment on SHIV(KU2) infection of rhesus macaques.

scientific article

Mechanisms of Platelet-Derived Growth Factor-BB in Restoring HIV Tat-Cocaine-Mediated Impairment of Neuronal Differentiation

scientific article published on 17 November 2015

Mechanisms of platelet-derived growth factor-mediated neuroprotection--implications in HIV dementia.

scientific article published on October 2008

MiR-9 promotes microglial activation by targeting MCPIP1.

scientific article

Mitigation of cocaine-mediated mitochondrial damage, defective mitophagy and microglial activation by superoxide dismutase mimetics

scientific article published on 28 April 2019

Molecular mechanism(s) involved in the synergistic induction of CXCL10 by human immunodeficiency virus type 1 Tat and interferon-gamma in macrophages

scientific article published on May 2008

Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration

scientific article

Molecular mechanisms of long noncoding RNAs and their role in disease pathogenesis.

scientific article

Monocytes-derived macrophages mediated stable expression of human brain-derived neurotrophic factor, a novel therapeutic strategy for neuroAIDS.

scientific article

More than two HANDs to tango

scientific article published on December 2013

Morphine enhances Tat-induced activation in murine microglia.

scientific article

Morphine induces expression of platelet-derived growth factor in human brain microvascular endothelial cells: implication for vascular permeability

scientific article

Morphine potentiates neuropathogenesis of SIV infection in rhesus macaques

scientific article published on 24 March 2011

Morphine-Mediated Brain Region-Specific Astrocytosis Involves the ER Stress-Autophagy Axis

scientific article published on 17 January 2018

Morphine-mediated release of miR-138 in astrocyte-derived extracellular vesicles promotes microglial activation

scientific article published on 01 October 2020

Multiple Faceted Roles of Cocaine in Potentiation of HAND.

scientific article published on 24 March 2016

NLRP3 Inflammasome Blockade Reduces Cocaine-Induced Microglial Activation and Neuroinflammation

scientific article published on 08 January 2021

Neuroimmune pharmacology as an emerging curriculum for pre-medical students

scientific article

Neuronal apoptosis is mediated by CXCL10 overexpression in simian human immunodeficiency virus encephalitis

scientific article

Neuronal-derived extracellular vesicles are enriched in the brain and serum of HIV-1 transgenic rats

scientific article published on 20 December 2019

Neuropathogenesis of lentiviral infection in macaques: roles of CXCR4 and CCR5 viruses and interleukin-4 in enhancing monocyte chemoattractant protein-1 production in macrophages.

scientific article published on September 2002

Nonhuman primate models of NeuroAIDS

scientific article published on August 2008

Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: involvement of β1 integrins.

scientific article published on 4 January 2013

Opiates, immune system, acquired immunodeficiency syndrome, and nonhuman primate model.

scientific article

Opioid-Mediated HIV-1 Immunopathogenesis

scientific article published on 08 October 2020

PDGF-mediated protection of SH-SY5Y cells against Tat toxin involves regulation of extracellular glutamate and intracellular calcium

scientific article published on 02 July 2009

PDGF/PDGFR axis in the neural systems

scientific article published on 31 January 2018

Pericytes contribute to the disruption of the cerebral endothelial barrier via increasing VEGF expression: implications for stroke

scientific article published on 17 April 2015

Platelet-derived growth factor (PDGF)-BB-mediated induction of monocyte chemoattractant protein 1 in human astrocytes: implications for HIV-associated neuroinflammation

scientific article published on December 2012

Platelet-derived growth factor B chain is a novel target gene of cocaine-mediated Notch1 signaling: implications for HIV-associated neurological disorders

scientific article published on August 2011

Platelet-derived growth factor CC-mediated neuroprotection against HIV Tat involves TRPC-mediated inactivation of GSK 3beta.

scientific article

Platelet-derived growth factor protects neurons against gp120-mediated toxicity

scientific article published on January 2008

Platelet-derived growth factor-BB restores HIV Tat -mediated impairment of neurogenesis: role of GSK-3β/β-catenin.

scientific article

Platelet-derived growth factor-BB restores human immunodeficiency virus Tat-cocaine-mediated impairment of neurogenesis: role of TRPC1 channels

scientific article

Platelet-derived growth factor-mediated induction of the synaptic plasticity gene Arc/Arg3.1.

scientific article

Presence of Intact vpu and nef genes in nonpathogenic SHIV is essential for acquisition of pathogenicity of this virus by serial passage in macaques

scientific article

Proceedings from the NIMH symposium on "NeuroAIDS in Africa: neurological and neuropsychiatric complications of HIV".

scientific article published on 29 July 2016

Proceedings of the 2017 ISEV symposium on "HIV, NeuroHIV, drug abuse, & EVs".

scientific article

Proceedings of the ISEV symposium on "HIV, NeuroAIDS, drug abuse & EVs".

scientific article published on 10 March 2017

Proinflammatory cytokines and HIV-1 synergistically enhance CXCL10 expression in human astrocytes.

scientific article

Protection of macaques against AIDS with a live attenuated SHIV vaccine is of finite duration

scientific article published on 7 November 2007

Reactive Oxygen Species/Hypoxia-Inducible Factor-1α/Platelet-Derived Growth Factor-BB Autocrine Loop Contributes to Cocaine-Mediated Alveolar Epithelial Barrier Damage

scientific article published on 08 July 2016

Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy.

scientific article published on 17 October 2016

Responses of Pulmonary Platelet-Derived Growth Factor Peptides and Receptors to Hyperoxia and Nitric Oxide in Piglet Lungs

article

Reversible palmitoylation regulates surface stability of AMPA receptors in the nucleus accumbens in response to cocaine in vivo

scientific article

Rodent models of HAND and drug abuse: exogenous administration of viral protein(s) and cocaine.

scientific article

Role of Sigma Receptor in Cocaine-Mediated Induction of Glial Fibrillary Acidic Protein: Implications for HAND

scientific article published on 29 January 2015

Role of Sigma-1 Receptor in Cocaine Abuse and Neurodegenerative Disease.

scientific article published on January 2017

Role of endoplasmic reticulum (ER) stress in cocaine-induced microglial cell death

scientific article published on 13 February 2013

Role of interleukin-4 and monocyte chemoattractant protein-1 in the neuropathogenesis of X4 simian human immunodeficiency virus infection in macaques

scientific article

Role of nicotinic receptors and acetylcholine in mucous cell metaplasia, hyperplasia, and airway mucus formation in vitro and in vivo.

scientific article

Roles of MCP-1 in development of HIV-dementia

scientific article published on May 2008

SNIP Members in a Recent International Conference: World Summit of Antivirals

scientific article published on 11 November 2008

Selective transmission of R5-tropic HIV type 1 from dendritic cells to resting CD4+ T cells

scientific article published on January 2001

Simian human immunodeficiency virus-associated pneumonia correlates with increased expression of MCP-1, CXCL10, and viral RNA in the lungs of rhesus macaques

scientific article

Stability of surface NMDA receptors controls synaptic and behavioral adaptations to amphetamine.

scientific article

TRPC channel-mediated neuroprotection by PDGF involves Pyk2/ERK/CREB pathway.

scientific article published on 14 August 2009

Tat 101-mediated enhancement of brain pericyte migration involves platelet-derived growth factor subunit B homodimer: implications for human immunodeficiency virus-associated neurocognitive disorders.

scientific article

Tat-Mediated Induction of miRs-34a & -138 Promotes Astrocytic Activation via Downregulation of SIRT1: Implications for Aging in HAND.

scientific article published on 24 February 2017

The HTLV-I p30 interferes with TLR4 signaling and modulates the release of pro- and anti-inflammatory cytokines from human macrophages.

scientific article published on 19 June 2006

The sigma-1 receptor chaperone as an inter-organelle signaling modulator

scientific article

Therapy of ‘SHIV’ infected macaques with liposomes delivering antisense interleukin-4 DNA

scientific article published on 01 May 2006

Transactivation of TrkB by Sigma-1 receptor mediates cocaine-induced changes in dendritic spine density and morphology in hippocampal and cortical neurons

scientific article published on 13 October 2016

Transpososomes: Stable protein-DNA complexes involved in the in vitro transposition of bacteriophage Mu DNA

scientific article published on 01 April 1987

Upregulation of expression of platelet-derived growth factor and its receptor in pneumonia associated with SHIV-infected macaques.

scientific article published in January 2007

VZV reactivation: a comorbid connection?

scientific article published on 8 February 2014

Variable region 4 of SIV envelope correlates with rapid disease progression in morphine-exposed macaques infected with SIV/SHIV.

scientific article

Vitamin D receptor activation and downregulation of renin-angiotensin system attenuate morphine-induced T cell apoptosis.

scientific article

Yin and Yang of PDGF-mediated signaling pathway in the context of HIV infection and drug abuse

scientific article published on 20 June 2013

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