List of works - Mariano A Garcia-Blanco

5' exon replacement and repair by spliceosome-mediated RNA trans-splicing

scientific article

A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection

scientific article

A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation

scientific article published on 13 August 2020

A rapid and simple quantitative method for specific Detection of Smaller Co-terminal RNA by PCR (DeSCo-PCR): Application to the detection of viral subgenomic RNAs

scientific article published on 01 April 2020

Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity

scholarly article

Alternative splicing in multiple sclerosis and other autoimmune diseases

scientific article

Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer

scientific article

Biochemistry and Molecular Biology of Flaviviruses.

scientific article published on 13 April 2018

Cellular migration and invasion uncoupled: increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition

scientific article

Circulating tumor cells from patients with advanced prostate and breast cancer display both epithelial and mesenchymal markers

scientific article

Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6.

scientific article

Comparative Loss-of-Function Screens Reveal ABCE1 as an Essential Cellular Host Factor for Efficient Translation of and

scientific article published on 14 May 2019

Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness

scientific article published on 2 July 2015

Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission

scientific article published on 28 July 2017

Discovery of insect and human dengue virus host factors

scientific article

Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis

scientific article published on 04 July 2019

Factors affecting reproducibility between genome-scale siRNA-based screens

scientific article

Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing

scientific article

Flaviviral RNAs: weapons and targets in the war between virus and host

scientific article

Flavivirus RNA transactions from viral entry to genome replication

scientific article published on 22 September 2016

Fluorescence-based alternative splicing reporters for the study of epithelial plasticity in vivo

scientific article

Fox-2 mediates epithelial cell-specific fibroblast growth factor receptor 2 exon choice

scientific article (publication date: February 2006)

Fragile X mental retardation protein is a Zika virus restriction factor that is antagonized by subgenomic flaviviral RNA

scholarly article by Ruben Soto-Acosta et al published 4 December 2018 in eLife

Functional genomics approach for the identification of human host factors supporting dengue viral propagation

scientific article

G Protein-Coupled Receptor Kinase 2 Promotes Flaviviridae Entry and Replication ⬇️

scientific article published on September 13, 2012

G3BP1, G3BP2 and CAPRIN1 are required for translation of interferon stimulated mRNAs and are targeted by a dengue virus non-coding RNA.

scientific article

Human genetic variation and yellow fever mortality during 19th century U.S. epidemics

scientific article

Human transcription elongation factor CA150 localizes to splicing factor-rich nuclear speckles and assembles transcription and splicing components into complexes through its amino and carboxyl regions.

scientific article

Identification and characterization of host proteins bound to dengue virus 3' UTR reveal an antiviral role for quaking proteins.

scientific article

Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication.

scientific article

Inefficient recruitment of DDX39B impedes pre-spliceosome assembly on FOXP3 introns

scientific article published in 2024

Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis

scientific article

MHC Class III RNA Binding Proteins and Immunity

scientific article published on 06 December 2020

Making antisense of splicing.

scientific article

Messenger RNA reprogramming by spliceosome-mediated RNA trans-splicing

scientific article

N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection

scientific article (publication date: October 2016)

Of urchins and men: evolution of an alternative splicing unit in fibroblast growth factor receptor genes

scientific article

Provider-patient communication about Zika during prenatal visits

scientific article (publication date: September 2017)

RPLP1 and RPLP2 Are Essential Flavivirus Host Factors That Promote Early Viral Protein Accumulation

scientific article (publication date: 15 February 2017)

Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs

scientific article

Reprogramming of tau alternative splicing by spliceosome-mediated RNA trans-splicing: implications for tauopathies

scientific article

Reversible cross-linking combined with immunoprecipitation to study RNA-protein interactions in vivo

scientific article

SplicerAV: a tool for mining microarray expression data for changes in RNA processing

scientific article

SplicerEX: a tool for the automated detection and classification of mRNA changes from conventional and splice-sensitive microarray expression data

scientific article

Targeting host factors to treat West Nile and dengue viral infections

scientific article published on 10 February 2014

Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs

scientific article

The 5' and 3' Untranslated Regions of the Flaviviral Genome

scientific article

The Golgi associated ERI3 is a Flavivirus host factor

scientific article

The RNA binding protein Quaking represses host interferon response by downregulating MAVS

scientific article published on 19 December 2019

The RNA binding protein Quaking represses splicing of the Fibronectin EDA exon and downregulates the interferon response

scientific article published on 01 September 2021

The anti-immune dengue subgenomic flaviviral RNA is present in vesicles in mosquito saliva and is associated with increased infectivity ⬇️

scientific article published on 30 March 2023

The kinase inhibitor SFV785 dislocates dengue virus envelope protein from the replication complex and blocks virus assembly

scientific article

The polypyrimidine tract binding protein is required for efficient picornavirus gene expression and propagation

scientific article

The polypyrimidine tract-binding protein is required for efficient dengue virus propagation and associates with the viral replication machinery

scientific article

The role of epithelial plasticity in prostate cancer dissemination and treatment resistance

scientific article

Topoisomerase III-beta is required for efficient replication of positive-sense RNA viruses

scientific article (preprint)

Trans-splicing into highly abundant albumin transcripts for production of therapeutic proteins in vivo

scientific article

Using circulating tumor cells to inform on prostate cancer biology and clinical utility

scientific article

Zika Virus: Diagnosis, Therapeutics, and Vaccine

scientific article

Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network

scientific article

Zika virus: History, emergence, biology, and prospects for control

scientific article

List of works by Mariano A Garcia-Blanco

5' exon replacement and repair by spliceosome-mediated RNA trans-splicing

A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection

A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation

A rapid and simple quantitative method for specific Detection of Smaller Co-terminal RNA by PCR (DeSCo-PCR): Application to the detection of viral subgenomic RNAs

Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity

Alternative splicing in multiple sclerosis and other autoimmune diseases

Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer

Biochemistry and Molecular Biology of Flaviviruses.

Cellular migration and invasion uncoupled: increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition

Circulating tumor cells from patients with advanced prostate and breast cancer display both epithelial and mesenchymal markers

Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6.

Comparative Loss-of-Function Screens Reveal ABCE1 as an Essential Cellular Host Factor for Efficient Translation of and

Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness

Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission

Discovery of insect and human dengue virus host factors

Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis

Factors affecting reproducibility between genome-scale siRNA-based screens

Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing

Flaviviral RNAs: weapons and targets in the war between virus and host

Flavivirus RNA transactions from viral entry to genome replication

Fluorescence-based alternative splicing reporters for the study of epithelial plasticity in vivo

Fox-2 mediates epithelial cell-specific fibroblast growth factor receptor 2 exon choice

Fragile X mental retardation protein is a Zika virus restriction factor that is antagonized by subgenomic flaviviral RNA

Functional genomics approach for the identification of human host factors supporting dengue viral propagation

G Protein-Coupled Receptor Kinase 2 Promotes Flaviviridae Entry and Replication ⬇️

G3BP1, G3BP2 and CAPRIN1 are required for translation of interferon stimulated mRNAs and are targeted by a dengue virus non-coding RNA.

Human genetic variation and yellow fever mortality during 19th century U.S. epidemics

Human transcription elongation factor CA150 localizes to splicing factor-rich nuclear speckles and assembles transcription and splicing components into complexes through its amino and carboxyl regions.

Identification and characterization of host proteins bound to dengue virus 3' UTR reveal an antiviral role for quaking proteins.

Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication.

Inefficient recruitment of DDX39B impedes pre-spliceosome assembly on FOXP3 introns

Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis

MHC Class III RNA Binding Proteins and Immunity

Making antisense of splicing.

Messenger RNA reprogramming by spliceosome-mediated RNA trans-splicing

N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection

Of urchins and men: evolution of an alternative splicing unit in fibroblast growth factor receptor genes

Provider-patient communication about Zika during prenatal visits

RPLP1 and RPLP2 Are Essential Flavivirus Host Factors That Promote Early Viral Protein Accumulation

Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs

Reprogramming of tau alternative splicing by spliceosome-mediated RNA trans-splicing: implications for tauopathies

Reversible cross-linking combined with immunoprecipitation to study RNA-protein interactions in vivo

SplicerAV: a tool for mining microarray expression data for changes in RNA processing

SplicerEX: a tool for the automated detection and classification of mRNA changes from conventional and splice-sensitive microarray expression data

Targeting host factors to treat West Nile and dengue viral infections

Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs

The 5' and 3' Untranslated Regions of the Flaviviral Genome

The Golgi associated ERI3 is a Flavivirus host factor

The RNA binding protein Quaking represses host interferon response by downregulating MAVS

The RNA binding protein Quaking represses splicing of the Fibronectin EDA exon and downregulates the interferon response

The anti-immune dengue subgenomic flaviviral RNA is present in vesicles in mosquito saliva and is associated with increased infectivity ⬇️

The kinase inhibitor SFV785 dislocates dengue virus envelope protein from the replication complex and blocks virus assembly

The polypyrimidine tract binding protein is required for efficient picornavirus gene expression and propagation

The polypyrimidine tract-binding protein is required for efficient dengue virus propagation and associates with the viral replication machinery

The role of epithelial plasticity in prostate cancer dissemination and treatment resistance

Topoisomerase III-beta is required for efficient replication of positive-sense RNA viruses

Trans-splicing into highly abundant albumin transcripts for production of therapeutic proteins in vivo

Using circulating tumor cells to inform on prostate cancer biology and clinical utility

Zika Virus: Diagnosis, Therapeutics, and Vaccine

Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network

Zika virus: History, emergence, biology, and prospects for control