List of works - Ana Fernández-Sesma

A mouse model for immunization with ex vivo virus-infected dendritic cells

scientific article

A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses

scientific article (publication date: 9 March 2017)

A prospective, comparative study of the immune response to inactivated influenza vaccine in pediatric liver transplant recipients and their healthy siblings

scientific article

An Aedes aegypti-Derived Ago2 Knockout Cell Line to Investigate Arbovirus Infections

scientific article published in 2021

Antiviral immunity and the role of dendritic cells

scientific article

Attenuation and immunogenicity in mice of temperature-sensitive influenza viruses expressing truncated NS1 proteins

scientific article published in October 2005

BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.

scientific article

Cell Receptors for Influenza a Viruses and the Innate Immune Response ⬇️

scientific article published on March 28, 2012

Characterization of swine-origin H1N1 canine influenza viruses

scientific article published on 01 January 2019

Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS

scientific article published on 15 October 2020

Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells

scientific article published on 2 August 2007

Cofactors required for TLR7- and TLR9-dependent innate immune responses

scientific article published in March 2012

DENV inhibits type I IFN production in infected cells by cleaving human STING

scientific article published on 4 October 2012

Defining Hsp70 Subnetworks in Dengue Virus Replication Reveals Key Vulnerability in Flavivirus Infection

scientific article published on 11 November 2015

Dengue Virus Inhibits the Production of Type I Interferon in Primary Human Dendritic Cells

Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling

scientific article

Dengue virus inhibits the production of type I interferon in primary human dendritic cells

scientific article published on 17 February 2010

Differential Modulation of Innate Immune Responses in Human Primary Cells by Influenza A Viruses Carrying Human or Avian Nonstructural Protein 1

scientific article published on 12 December 2019

Effects of receptor binding specificity of avian influenza virus on the human innate immune response

scientific article published on 23 February 2011

Estrogen inhibits dendritic cell maturation to RNA viruses.

scientific article published on 18 September 2008

Evasion of the human innate immune system by dengue virus

scientific article

Finding Clues for Congenital Zika Syndrome: Zika Virus Selective Infection of Immature Neurons

scientific article

H7N9 influenza viruses interact preferentially with α2,3-linked sialic acids and bind weakly to α2,6-linked sialic acids

scientific article published on 15 August 2013

HIV Vpu Interferes with NF-κB Activity but Not with Interferon Regulatory Factor 3.

scientific article

HIV-1 interacts with human endogenous retrovirus K (HML-2) envelopes derived from human primary lymphocytes

scientific article

Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus

scientific article published on July 2015

Herpes simplex virus 2 (HSV-2) prevents dendritic cell maturation, induces apoptosis, and triggers release of proinflammatory cytokines: potential links to HSV-HIV synergy

scientific article published on 14 November 2012

Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses

scientific article

Humoral and cell-mediated immune responses to monovalent 2009 influenza A/H1N1 and seasonal trivalent influenza vaccines in high-risk children

scientific article

IL-15 regulates susceptibility of CD4 T cells to HIV infection

article published in the Proceedings of the National Academy of Sciences of the United States of America

Imd pathway-specific immune assays reveal NF-κB stimulation by viral RNA PAMPs in Aedes aegypti Aag2 cells

scientific article published on 16 February 2021

Influenza virus evades innate and adaptive immunity via the NS1 protein

scientific article published on July 2006

Inhibition of the type I interferon response in human dendritic cells by dengue virus infection requires a catalytically active NS2B3 complex

scientific article

Innate Immune Response to Influenza Virus at Single-Cell Resolution in Human Epithelial Cells Revealed Paracrine Induction of Interferon Lambda 1

scientific article published on 30 September 2019

Innate Immunity to H5N1 Influenza Viruses in Humans ⬇️

scientific article published on December 1, 2012

Innate immune sensing of flaviviruses

scientific article

Innate immunity evasion by Dengue virus

scientific article

Interferon-beta pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus

scientific article

Message in a bottle: lessons learned from antagonism of STING signalling during RNA virus infection

scientific article published on 24 August 2014

Modulating the Innate Immune Response to Influenza A Virus: Potential Therapeutic Use of Anti-Inflammatory Drugs

scientific article (publication date: 2015)

Mouse STAT2 restricts early dengue virus replication

scientific article published in November 2010

Mucosal immunization with attenuated Shigella flexneri harboring an influenza hemagglutinin DNA vaccine protects mice against a lethal influenza challenge.

scientific article published in August 2004

Mutational analysis of the influenza virus vRNA promoter

scientific article published in May 1993

Myeloid dendritic cells stimulate both Th1 and Th2 immune responses depending on the nature of the antigen

scientific article

Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death.

scientific article

Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-γ.

scientific article

Protection against respiratory syncytial virus by a recombinant Newcastle disease virus vector

scientific article

Recombinant influenza A viruses with enhanced levels of PB1 and PA viral protein expression

scientific article published on 7 March 2012

Role of the influenza virus nonstructural 1 protein in evasion of immunity

SAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infection

scientific article published in December 2011

Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis

scientific article

Serological detection of West Nile virus in horses and chicken from Pantanal, Brazil

scientific article published on December 2012

Synthetic Toll-like receptor 4 (TLR4) and TLR7 ligands as influenza virus vaccine adjuvants induce rapid, sustained, and broadly protective responses

scientific article

Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection

scientific article published on January 2016

Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection

article

Th2 responses to inactivated influenza virus can Be converted to Th1 responses and facilitate recovery from heterosubtypic virus infection

scientific article published on September 1999

The DBA.2 mouse is susceptible to disease following infection with a broad, but limited, range of influenza A and B viruses

scientific article published on 14 September 2011

The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors

scientific article published on February 2013

The NS1 protein of a human influenza virus inhibits type I interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells

scientific article published on 29 April 2009

The burden of dengue and chikungunya worldwide: implications for the southern United States and California

scientific article published on November 2014

The influenza virus NS1 protein: inhibitor of innate and adaptive immunity

scientific article published on December 2007

The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein

scientific article

Tumor suppressor cylindromatosis (CYLD) controls HIV transcription in an NF-κB-dependent manner

scientific article published on 23 April 2014

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response

scientific article

Zika Virus: More Questions Than Answers

scientific article

mSphere of Influence: the View from the Microbiologists of the Future.

scientific article published on 19 June 2019

List of works by Ana Fernández-Sesma

A mouse model for immunization with ex vivo virus-infected dendritic cells

A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses

A prospective, comparative study of the immune response to inactivated influenza vaccine in pediatric liver transplant recipients and their healthy siblings

An Aedes aegypti-Derived Ago2 Knockout Cell Line to Investigate Arbovirus Infections

Antiviral immunity and the role of dendritic cells

Attenuation and immunogenicity in mice of temperature-sensitive influenza viruses expressing truncated NS1 proteins

BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency.

Cell Receptors for Influenza a Viruses and the Innate Immune Response ⬇️

Characterization of swine-origin H1N1 canine influenza viruses

Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS

Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells

Cofactors required for TLR7- and TLR9-dependent innate immune responses

DENV inhibits type I IFN production in infected cells by cleaving human STING

Defining Hsp70 Subnetworks in Dengue Virus Replication Reveals Key Vulnerability in Flavivirus Infection

Dengue Virus Inhibits the Production of Type I Interferon in Primary Human Dendritic Cells

Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling

Dengue virus inhibits the production of type I interferon in primary human dendritic cells

Differential Modulation of Innate Immune Responses in Human Primary Cells by Influenza A Viruses Carrying Human or Avian Nonstructural Protein 1

Effects of receptor binding specificity of avian influenza virus on the human innate immune response

Estrogen inhibits dendritic cell maturation to RNA viruses.

Evasion of the human innate immune system by dengue virus

Finding Clues for Congenital Zika Syndrome: Zika Virus Selective Infection of Immature Neurons

H7N9 influenza viruses interact preferentially with α2,3-linked sialic acids and bind weakly to α2,6-linked sialic acids

HIV Vpu Interferes with NF-κB Activity but Not with Interferon Regulatory Factor 3.

HIV-1 interacts with human endogenous retrovirus K (HML-2) envelopes derived from human primary lymphocytes

Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus

Herpes simplex virus 2 (HSV-2) prevents dendritic cell maturation, induces apoptosis, and triggers release of proinflammatory cytokines: potential links to HSV-HIV synergy

Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses

Humoral and cell-mediated immune responses to monovalent 2009 influenza A/H1N1 and seasonal trivalent influenza vaccines in high-risk children

IL-15 regulates susceptibility of CD4 T cells to HIV infection

Imd pathway-specific immune assays reveal NF-κB stimulation by viral RNA PAMPs in Aedes aegypti Aag2 cells

Influenza virus evades innate and adaptive immunity via the NS1 protein

Inhibition of the type I interferon response in human dendritic cells by dengue virus infection requires a catalytically active NS2B3 complex

Innate Immune Response to Influenza Virus at Single-Cell Resolution in Human Epithelial Cells Revealed Paracrine Induction of Interferon Lambda 1

Innate Immunity to H5N1 Influenza Viruses in Humans ⬇️

Innate immune sensing of flaviviruses

Innate immunity evasion by Dengue virus

Interferon-beta pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus

Message in a bottle: lessons learned from antagonism of STING signalling during RNA virus infection

Modulating the Innate Immune Response to Influenza A Virus: Potential Therapeutic Use of Anti-Inflammatory Drugs

Mouse STAT2 restricts early dengue virus replication

Mucosal immunization with attenuated Shigella flexneri harboring an influenza hemagglutinin DNA vaccine protects mice against a lethal influenza challenge.

Mutational analysis of the influenza virus vRNA promoter

Myeloid dendritic cells stimulate both Th1 and Th2 immune responses depending on the nature of the antigen

Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death.

Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-γ.

Protection against respiratory syncytial virus by a recombinant Newcastle disease virus vector

Recombinant influenza A viruses with enhanced levels of PB1 and PA viral protein expression

Role of the influenza virus nonstructural 1 protein in evasion of immunity

SAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infection

Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis

Serological detection of West Nile virus in horses and chicken from Pantanal, Brazil

Synthetic Toll-like receptor 4 (TLR4) and TLR7 ligands as influenza virus vaccine adjuvants induce rapid, sustained, and broadly protective responses

Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection

Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection

Th2 responses to inactivated influenza virus can Be converted to Th1 responses and facilitate recovery from heterosubtypic virus infection

The DBA.2 mouse is susceptible to disease following infection with a broad, but limited, range of influenza A and B viruses

The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors

The NS1 protein of a human influenza virus inhibits type I interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells

The burden of dengue and chikungunya worldwide: implications for the southern United States and California

The influenza virus NS1 protein: inhibitor of innate and adaptive immunity

The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein

Tumor suppressor cylindromatosis (CYLD) controls HIV transcription in an NF-κB-dependent manner

Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response

Zika Virus: More Questions Than Answers

mSphere of Influence: the View from the Microbiologists of the Future.